Healthcare Unfiltered artwork

Healthcare Unfiltered

182 episodes - English - Latest episode: 9 days ago - ★★★★★ - 125 ratings

Healthcare Unfiltered is an honest, raw, timely podcast tackling any and all topics in healthcare that affect stakeholders. Dr. Chadi Nabhan uses his dynamic conversational skills to challenge his guests to address controversial and important topics. He also brings on world renowned experts to discuss clinical advances in medicine.

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Episodes

Reducing Out-of-Pocket Prescription Costs With Kyle Kiser

May 02, 2023 10:49 - 41 minutes - 76.3 MB

Kyle Kiser, CEO of Arrive Health, joins the show to highlight his company’s unique approach to lowering costs of prescription drugs for patients in the US. He explains how physicians often make changes to their prescription recommendations based on Arrive Health’s presence as an “invisible component within the EMR,” how they aggregate data to generate clinical alternatives and relevant alternatives to payer preferences, how they maneuver around prior authorizations, the need (or lack thereof)...

Quality of Life, Patient-Reported Outcomes, and Clinical Trials

April 25, 2023 11:02 - 1 hour - 120 MB

Chadi hosts a duo of Canadiens to discuss quality of life and patient-reported outcomes in clinical trials: Christopher Booth, MD, and Michael Brundage, MSc, FRCPC, MD, both of Queen's University. They begin by pontificating on whether quality of life is a “must” endpoint in designing interventional clinical trials today, the timeline of how “PROs” came to be a term and an important component of clinical trials, how PRO measures should differ across disease types and trials, and how PROs shou...

“The Fun Habit” With Mike Rucker

April 18, 2023 10:53 - 51 minutes - 93.7 MB

Mike Rucker, PhD, a behavioral scientist and organizational psychologist, joins the show to discuss his writing and publishing of the book “The Fun Habit: How the Pursuit of Joy and Wonder Can Change Your Life.” Dr. Rucker explains how you can build having fun into an “actionable and effortless habit” and simultaneously reduce burnout. He shares why Americans have a difficult time enjoying themselves outside of work, what it means to “stop chasing happiness and start having fun,” what kind of...

Debate of the Decade: RCTs in the Era of Precision Oncology

April 11, 2023 10:39 - 1 hour - 146 MB

How do you design clinical trials in the era of precision oncology? Are prospective randomized controlled trials necessary anymore? Drs. Ray Kurzrock, Vivek Subbiah, and Christopher Booth drop the gloves and debate these questions - beginning with the definition of “precision oncology,” what phase the trials should be when initially designing, and whether accelerated approval and surrogate endpoints are truly helping patients in the precision oncology era. The group also analyzes specific exa...

“Toxic Exposure” Review With Kelly Ryerson and Mikkael Sekeres

April 04, 2023 10:42 - 56 minutes - 103 MB

In a change-of-pace episode, Chadi has the tables turned on him as he is interviewed by two supporters and reviewers of his new book “Toxic Exposure: The True Story behind the Monsanto Trials and the Search for Justice.” Kelly Ryerson, MBA, GlyphosateGirl.com, and Mikkael Sekeres, author of “Drugs and the FDA: Safety, Efficacy, and the Public's Trust” and “When Blood Breaks Down: Life Lessons from Leukemia,” ask Chadi to comment on why he was chosen as an expert witness, how glyphosate causes...

Pharma and Academia: Dr. Charles Bennett's Battle

March 28, 2023 10:52 - 51 minutes - 93.4 MB

In the latest book review, Chadi hosts the authors of the successful expose of his former colleague in “Taking On Big Pharma: Dr. Charles Bennett's Battle.” Julius Getman and Terri LeClercq share how they met Dr. Bennett on a cruise and became interested in his story about his massive achievements and legal charges against him - mishandling government grant money and violating the False Claims Act. They begin with their reasons for believing that the case against Dr. Bennett was baseless and ...

A Shocking Whistleblower Story With Linda Martin

March 21, 2023 10:51 - 1 hour - 113 MB

A story about adverse reactions, the FDA, the FBI, and patients - Linda Martin, a healthcare executive, shares with Chadi a riveting dialogue about the events in her life that have transpired since she got sick and started taking a standard prescribed antibiotic. Linda tells the story of when and why she was prescribed the antibiotic, how it made her feel worse than before, and how she found similar stories of bad reactions to this drug online. Then, she explains the series of events that led...

Integrating APPs Into Oncology Care

March 14, 2023 10:52 - 51 minutes - 94.8 MB

To better understand the role and importance of Advanced Practice Providers in oncology care, Chadi hosts Sarah Wyman, MSN, ACNP-BC, and Katie Simon, MMSc, PA-C, both co-leads of the APPs on the inpatient malignant hematology services team at Emory University Winship Cancer Institute. They begin by explaining the similar training and skill sets of NPs and PAs, the history of these positions over the past 25 years, and the day-to-day responsibilities for inpatient APPs. Then, they share how di...

Cytogenetics and Cancer Care With Linda Baughn and Yassmine Akkari

March 07, 2023 11:57 - 58 minutes - 106 MB

In the world of whole-genome sequencing, do we really need cytogenetics anymore? To answer this question, Chadi brings on two cytogeneticists: Linda Baughn, PhD, and Yassmine Akkari, PhD. They begin by describing their unique career paths to becoming cytogeneticists, their day-to-day responsibilities, and what tests they perform and on what specimens. They then simplify the commonly used assays in their labs, how cytogenetic techniques are evolving (rather than dying), what whole genome seque...

The Monsanto Saga and Launch of “Toxic Exposure” With Nassim Nicholas Taleb

February 28, 2023 12:00 - 1 hour - 129 MB

Today is the day of the official launch of Chadi’s first book “Toxic Exposure: The True Story behind the Monsanto Trials and the Search for Justice.” Throughout the book, Chadi details his experience as an expert physician witness and the true story of the first three litigation trials against Monsanto and their herbicide "Roundup" which is linked to the development of Non-Hodgkin Lymphoma. The special guest on this unique day is the amazing icon and legend Dr. Nassim Nicholas Taleb. Dr. Tal...

A Conversation With an ASH President

February 21, 2023 11:42 - 49 minutes - 89.8 MB

In this special episode, Chadi hosts his previous mentor from his days as a fellow at Northwestern: Martin Tallman, MD, previous president of the American Society of Hematology (ASH) and world renowned leukemia expert. Together, they discuss mentorship and what makes a good mentor, where Dr. Tallman’s interest in leukemia came from and why he decided to begin his career in Seattle, his road to becoming an ASH president and how his day-to-day responsibilities changed after his election, reason...

For Blood and Money: A Biotech Story

February 14, 2023 11:58 - 59 minutes - 108 MB

Nathan Vardi, managing editor at MarketWatch, and author of the new book “For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug,” is the guest of honor on today’s show. Nathan divulges on what happened behind closed doors for the creation of BTK inhibitors. Everything at the intersection of Wall Street, investigators, doctors, regulatory agencies, investors, and VC is detailed. He begins by explaining the inspiration to cover this story and how willing individuals w...

BTK-Inhibitor Development: A Researcher's Perspective

February 07, 2023 11:50 - 55 minutes - 101 MB

Few drugs in oncology have transformed the way we take care of patients. Ibrutinib is one such drug, and it belongs to a class called "BTK inhibitors" In this episode, Chadi captures the story of developing the drug through the eyes of Dr. Jeff Sharman, a prolific investigator and researcher; he is the director of research at the Willamette Valley Cancer Institute as well as the medical director of hematology research for The US Oncology Network. Dr. Sharman begins by discussing the dynami...

The Journey of a Healthcare Startup CEO With Jennifer Fried

January 31, 2023 11:47 - 51 minutes - 94.9 MB

Jennifer Fried, MBA, most recently the CEO of ExplORer Surgical, joins the show to share her story as a co-founder of a successful startup health technology company. She begins by telling her inspiration to start the company with her partner, when and how operating room workflow and efficiency was discovered as an area of unmet need, the steps she took to create the software platform solution and how it functions, struggles she faced when facing potential investors, how the pandemic propelled...

Diet, Exercise, and Lifestyle Decisions for Cancer Patients With Urvi Shah and Neil Lyengar

January 24, 2023 11:41 - 1 hour - 125 MB

What do we know about various diets and their association with cancer? Have you ever wondered what the evidence shows? To answer this important question, Chadi hosts two specialists from Memorial Sloan Kettering Cancer Center: Urvi Shah, MD, hematologist oncologist (myeloma expert and a cancer survivor herself), and Neil Lyengar, MD, medical oncologist (breast cancer expert). They discuss whether there’s a direct cause-and-effect relationship between lack of exercise and cancer diagnoses and...

Should Low-Grade Prostate Cancer Be Considered Cancer?

January 17, 2023 11:48 - 56 minutes - 104 MB

Scott Eggener, MD, University of Chicago, and Jonathan Epstein, MD, The Johns Hopkins Medical Institutions, join the show to debate whether Gleason Score 6 prostate cancer should be renamed to non-cancer. The trio hit on what should happen upon diagnosis and Gleason grade 6, which patients should be offered active surveillance, the benefits and risks of not calling this diagnosis “cancer,” how often and how frequently to biopsy, overscreening, and many other discussion points. Read Dr. Eggen...

The History and Future of Precision Medicine with Ray Kurzrock

January 10, 2023 12:20 - 1 hour - 115 MB

Chadi is delighted and honored to host an icon and pioneer in precision medicine and the molecular understanding of cancer as we know it: Ray Kurzrock, MD, FACP, Center Associate Director and Professor at the Medical College of Wisconsin as well as CMO of the WIN consortium. Nobody knows the history of precision medicine like Ray does. She was doubted when she started, but her resilience and perseverance led to unprecedented progress that she led along with her mentors, mentees, and colleag...

Cancer in the Arab World with Humaid AlShamsi

January 03, 2023 11:45 - 1 hour - 111 MB

To educate on oncology in the Arab world—home to over 400 million people—Chadi welcomes a new and renowned guest: Humaid AlShamsi, MD, President of the Emirates Oncology Society and Adjunct Clinical Professor of Oncology at the University of Sharjah (UAE). Dr AlShamsi shares his unique journey training as an oncologist all over the world before returning to the UAE, initial challenges he encountered transforming care upon returning to his home country, and his detailed experience writing his ...

Access to Optimal Care: Disparities Between EU and US

December 27, 2022 11:56 - 52 minutes - 96.9 MB

To shed light on the differences in oncologic care between the US and the EU, Chadi invites a returning guest as well as a newcomer: Jarushka Naidoo, MBBCH, MD, Chair of the Thoracic Oncology Division, Beaumont RCSI Cancer Centre (Dublin, Ireland), and Marina Chiara Garassino, MD, Professor of Medicine, University of Chicago Medicine. The trio discuss discrepancies in diagnostics and pathology, how tissue samples are handled at molecular laboratories, treatment (oral and intravenous) and biop...

COIs and Pharma Physician Payments with Christopher Booth

December 20, 2022 11:52 - 57 minutes - 105 MB

In his second appearance on the show, Christopher Booth, MD, Professor in the Departments of Oncology and Medicine as well as a Health Services Researcher, Queen's University (Canada), shares his unique career path and early considerations of conflicts of interest in the medical world, how the influences of pharma relationships are more subtle than expected, whether you can be a clinical trialist without working with pharma, and how the system can be changed to truly benefit patients. Additio...

AI in Global Medicine and Underserved Countries

December 06, 2022 11:59 - 1 hour - 112 MB

To tackle some of the burning questions and concerns in global medicine—specifically in radiology, diagnostics, and AI—Chadi hosts a Healthcare Unfiltered mainstay as well as a new guest: Saurabh Jha, MD, radiologist at the University of Pennsylvania and self-proclaimed “global radiology enthusiast,” and Prashant Warier, co-founder and the CEO of Qure AI. The trio begin by detailing the development of AI in underserved countries for the diagnosis of tuberculosis and other diseases, continue b...

Surrogate Endpoints in Solid and Liquid Tumors

November 29, 2022 11:48 - 1 hour - 127 MB

Brothers Rakesh Popat, PhD, multiple myeloma expert, and Sanjay Popat, PhD, thoracic oncologist, join the show for a special discourse on surrogate endpoints and patient benefit. The conversation fluctuates between the “assumption” that surrogate endpoints translate to better survival; breakdowns of the utility and association with overall survival of PFS, ORR, and MRD in the latest literature; reimbursement intricacies and issues surrounding surrogate endpoint criteria; and the need for stro...

Podcasting for Patients: Adam Cifu’s Latest Venture

November 22, 2022 03:07 - 41 minutes - 76.5 MB

Returning to the show is Adam Cifu, MD, University of Chicago, to tell us about his exciting new podcast venture. “The Clinical Excellence Podcast” is dedicated to discussing issues with clinicians, patients, and researchers studying the doctor-patient relationship. Dr. Cifu shares the tricky conversations that doctors and patients have (eg, terminating patient relationships, burnout, second opinions, caring for colleagues, and others), how those will be featured on the podcast, topics that m...

Challenges and Bias against IMGs in America

November 15, 2022 07:14 - 1 hour - 152 MB

Chadi hosts a roundtable of five guests—four first-timers and one recurring guest—to discuss the challenges of international medical graduates (IMGs) in oncology and medicine in general in the US. Led by Ayesha Butt, MBBS, Department of Internal Medicine, Yale School of Medicine, the group discusses the findings of a recent nationwide survey, published in JCO Oncology Practice, that uncovered bias against IMGs in the hem/onc fellowship recruitment process. Additionally, they cover the strug...

Challenges and Bias against IMGs in America

November 15, 2022 07:14 - 1 hour - 152 MB

Chadi hosts a roundtable of five guests—four first-timers and one recurring guest—to discuss the challenges of international medical graduates (IMGs) in oncology and medicine in general in the US. Led by Ayesha Butt, MBBS, Department of Internal Medicine, Yale School of Medicine, the group discusses the findings of a recent nationwide survey, published in JCO Oncology Practice, that uncovered bias against IMGs in the hem/onc fellowship recruitment process. Additionally, they cover the strug...

The Inflation Reduction Act: What's Next?

November 08, 2022 00:42 - 57 minutes - 105 MB

Making her long-awaited return to the show is Stacie Dusetzina, PhD, Professor of Health Policy and the Ingram Professor of Cancer Research, Vanderbilt University Medical Center – this time to discuss and simplify the Inflation Reduction Act that was recently signed into law. She begins by giving the background inspiration of the Act, whether reducing inflation is the true purpose of the Act, how the Act impacts Medicare and negotiating drug prices, how the drugs to be negotiated are select...

Twitter's Most Admired Couple: Aaron and Amalia

November 01, 2022 11:05 - 1 hour - 134 MB

In this change-of-pace episode, Chadi hosts show-regular Aaron Goodman and his wife: Amalia Aleck, MD, UC San Diego. The couple sit down for a casual conversation on how they met and their love story, applying for residencies and full-time employment as a couple, balancing their professional and family lives together and the inherent sacrifices they’ve had to make, the dynamics of “Papa Hem” on Twitter and their relationship on this platform, her support of his musical ambitions, and many oth...

Separating Hype from Hope for Cancer Patients

October 25, 2022 10:57 - 59 minutes - 109 MB

Christopher Booth, MD, Professor in the Departments of Oncology and Medicine as well as a Health Services Researcher, Queen's University (Canada), brings a different perspective to the show on healthcare policy and where the cancer system may be failing patients. Dr. Booth shares the “desert island” hypothetical scenario he used in a previous publication in which he asked oncologists all over the world for their 10 cancer drugs they would take to the “island” to help their patients. Then, he ...

ESMO-GI Update: The Amazing Chalabi Plot

October 18, 2022 10:54 - 57 minutes - 105 MB

Dr. Myriam Chalabi, a GI oncologist at the Netherlands Cancer Institute, joins the show after making waves at the latest ESMO Congress for her NICHE-2 study – an assessment of neoadjuvant immune checkpoint inhibition in locally advanced dMMR colon cancer. She shares the initial inspiration to give neoadjuvant immunotherapy for dMMR tumors, the surprisingly positive early results that led to expanding the study, her feelings and expectations leading up to her talk at ESMO, and her reaction to ...

Hyperemesis Gravidarum: The Truth and the Myths

October 11, 2022 10:50 - 1 hour - 150 MB

To tackle the relatively unknown topic of Hyperemesis Gravidarum (HG), Chadi invites four experts from the Hyperemesis Education & Research (HER) Foundation: Kimber MacGibbon, RN, executive director and co-founder; Aimee Brecht-Doscher, MD, adviser and long-time supporter; Kelly Ryerson, MBA, chair of the board of directors; and Marlena Fejzo, PhD, survivor of HG and research advisor. The group begins by defining HG—with respect to the traditional definition as well as the modern understandin...

Drugs and the FDA: A New Book With Mikkael Sekeres

October 04, 2022 10:53 - 1 hour - 125 MB

Recurring guest Mikkael A. Sekeres, MD, Professor of Medicine and Chief of the Division of Hematology, Sylvester Comprehensive Cancer Center, is today’s guest of honor to discuss and spotlight his just-published book: Drugs and the FDA: Safety, Efficacy, and the Public's Trust. Dr. Sekeres begins by sharing an anecdote of his experience on the FDA Oncologic Drugs Advisory Committee (ODAC) for Avastin as an inspiration to write the book. Then, he delves into the detailed process of becoming an...

OVERDOSE: A Real Tragedy Needing Solutions

September 27, 2022 10:43 - 1 hour - 124 MB

In this somber and forewarning episode, Chadi hosts Jodi Odell, mother of the late Jackson Odell – actor and victim of an accidental drug overdose. Jodi tells the background of Jackson’s life—from his early childhood days up through his final days at 20 years old—as a backdrop for a commentary on the drug overdose pandemic and addiction. Then, she shares his journey from rehab to a sober home, recounts the harrowing details of his final moments alive, and details the weeks that followed, up t...

Synthetic Control Arms and the Regulatory Maze

September 20, 2022 11:04 - 1 hour - 116 MB

Vivek Subbiah, MD, executive director of medical oncology research, MD Anderson Cancer Network, makes his triumphant return to the show to break down designing clinical trials for investigative therapies and the regulatory maze that follows before these therapies can find their way to the market. Dr. Subbiah begins by using precision medicine advances in lung cancer as a backdrop for the discussion on histology agnostic drug approvals. Then, he moves into the full regulatory flow map of how d...

CLL and the Patient Perspective

September 13, 2022 10:55 - 1 hour - 154 MB

Chadi convenes yet another expert roundtable to discuss CLL with a few returning guests as well as a physician-patient: Liz Brem, MD, assistant clinical professor of hematology, UC Irvine, Alan Skarbnik, MD, director of the lymphoma and CLL program, Novant Health (Charlotte, NC), and Brian Koffman, MDCM, FCFP, DABFM, MS Ed, executive vice president and chief medical officer, CLL Society. The group begins by stating that patients have little-to-no participation in treatment guidelines for CLL,...

Evidence-Based Medicine in a COVID World

September 11, 2022 14:30 - 58 minutes - 106 MB

Adam Cifu, MD, general internist and professor of medicine at the University of Chicago, is fresh off his rounds and ready to talk about the advantages and pitfalls of evidence-based medicine in today’s medical world. Dr. Cifu offers his thoughts on the level of evidence needed for vaccinations in children as well as the number of vaccinations and boosters needed for adults, what the evidence tells us about long COVID, whether mask wearing on planes and various other locations still carries a...

Naturopathic and Complementary Medicine: What is it?

August 30, 2022 10:32 - 1 hour - 140 MB

To explain and dissect the world of naturopathic medicine, Chadi hosts Nasha Winters, ND, FABNO, a renowned speaker and author on the topic. Dr. Winters shares her background of a devastating, terminal ovarian cancer diagnosis 30 years ago, the nontraditional care she received that put her on the road to recovery, and how that set things in motion for her career. Then, Dr. Winters expands on a system she has developed to understand the tumor “terrain” rather than the tumor itself, patient cas...

Practicing Oncology in Low and Middle Income Countries

August 23, 2022 10:55 - 1 hour - 124 MB

Nikita Mehra, medical oncologist in India, and Guilherme Perini, hematologist in Brazil, join the show to give a first-hand perspective on what it’s like to practice oncology in low and middle income countries. They begin by explaining variation in income levels and cancer care access within their own cities, expound on screening programs and ability to travel for care among their populations, share the testing and diagnostics procedures and availability, describe the market and supply of tre...

Radiopharmaceuticals: Resolving an Enigma

August 16, 2022 10:50 - 1 hour - 142 MB

Hosted by Ralph Weichselbaum, MD, Chair of the Department of Radiation and Cellular Oncology, University of Chicago, this episode tackles the burgeoning world of radiopharmaceuticals and features two radiation oncologists: Jeff Michalski, MD, MBA, Washington University in St. Louis and president of ASTRO, and Freddy Escorcia, MD, PhD, National Cancer Institute and National Institutes of Health. They kick it off by giving background context on isotope therapy and the current data for these the...

Careers in Medicine, Mentorship, and Medical Meetings

August 09, 2022 10:51 - 1 hour - 166 MB

Drs. Ross Levine, David Steensma, and a surprise recurring guest form a roundtable on today’s show to discuss making the career choice of a non-PhD lab-based scientist and what that entails on a day-to-day basis, how mentoring individuals in other labs is a rewarding and continuous process, what makes a good mentor, managing and securing grant funding for lab research (including the secrets of writing effective grants), making the transition from the clinic to industry and the day-to-day expe...

Advances and Controversies in Thoracic Oncology

August 02, 2022 11:02 - 1 hour - 118 MB

Jarushka Naidoo, MBBCH, MD, Chair of the Thoracic Oncology Division, Beaumont RCSI Cancer Centre (Dublin, Ireland), and Stephen Liu, MD, Director of Thoracic Oncology and Director of Developmental Therapeutics, Lombardi Comprehensive Cancer Center of Georgetown University, join the show to preview all of the important and exciting advancements in thoracic oncology leading up to the IASLC 2022 World Conference on Lung Cancer. The trio cover early-stage lung cancer, pathologic response as a sur...

Can Urologists Spearhead Medical Oncology Research?

July 26, 2022 10:56 - 55 minutes - 101 MB

Chadi hosts Dr. Neal Shore, a urologic oncologist who became heavily involved in GU oncology research – including trials that incorporate systemic chemotherapy. Dr. Shore has a unique practice where he and his staff deliver chemotherapy when appropriate. Chadi was intrigued by this setting as medical oncologists are the ones customarily delivering chemotherapy, and invited him to the show to share how this all started, its pros and cons, and the impact on patients. Dr. Shore explains how the...

Nuances of the Newest Leukemia Classification

July 19, 2022 10:50 - 58 minutes - 108 MB

Returning guests Sanam Loghavi, MD, hematopathologist and molecular pathologist, University of Texas MD Anderson Center, and Aaron Goodman, MD, hematologist, University of California San Diego, break down the latest classification system updates in leukemia. They begin by explaining what triggers a new classification and why it is needed, how soon clinicians should adopt it, and the relationship as well as differences between the ICC and WHO classification systems. Then, the experts go into t...

Complexities of Designing Clinical Trials

July 12, 2022 10:53 - 1 hour - 154 MB

On this special episode, Chadi hosts three phenomenal physicians to help us better understand the complexity of designing and executing clinical trials. Hira Mian, MD, faculty of health sciences, McMaster University (Canada), and Murali Janakiram, MD, MS, assistant professor, City of Hope, both faced and continue to face challenges in bringing their clinical trial ideas to light. Saad Usmani, MD, MBA, FACP, chief of myeloma service, Memorial Sloan Kettering Cancer Center, joins as a senior in...

Pharmacovigilance and Adherence to Oral Oncolytics

July 05, 2022 10:55 - 55 minutes - 101 MB

Joining Chadi on today’s show is Donald Harvey, PharmD, BCOP, FCCP, FHOPA, Winship Cancer Institute of Emory University. Dr. Harvey shares available career paths and how the pharmacist role has evolved over the years, how pharmacists continue to stay involved with patients after discharge, strategies he uses to help cancer patients adhere to oral oncolytics, and his “Call to Action” to improve such adherence – as co-planned by the FDA and ASCO and published in Journal of Clinical Oncology. Th...

Daring Greatly: Career Change of a Physician to a Life Coach

June 28, 2022 10:54 - 56 minutes - 103 MB

Christina Arnold, MD, gastrointestinal pathologist, University of Colorado, is today’s guest of honor discussing her unconventional career change to a full-time professional “life coach.” Dr. Arnold explains what inspired her to make this change, differentiates a life coach from a psychotherapist and how people should know which professional they need to see, reminds us how mental health is still under-resourced and forgotten among healthcare workers, shares her decision process for choosing ...

Carving Out a Healthcare Career Beyond Providership

June 21, 2022 10:57 - 51 minutes - 93.7 MB

Lee Shapiro, co-founder and managing partner at 7wireVentures, joins the show to discuss his unique journey through healthcare, entrepreneurship, and more. He begins by addressing broken business processes in healthcare as part of his early investment strategy, what he looks for in potential investment opportunities, how he forecasts investment in health technology in the coming years, past investment regrets (with a couple of specific company examples), his thoughts on PBMs, experiences taki...

Monkeypox: Fact From Fiction

June 14, 2022 10:47 - 34 minutes - 63.1 MB

Chadi hosts recurring guest Priya Sampathkumar (@PSampathkumarMD), MD, infectious disease specialist and hospital epidemiologist, Mayo Clinic, to provide the infectious disease profile of Mokeypox – the latest virus that is spreading globally and making its rounds in the media over the past few weeks. Dr. Sampathkumar highlights the virus’ symptom profile, differentiates it from Smallpox, explains the origins of infection in the US, shares theories for why the infection rate is increasing wor...

Multiple Myeloma With Multiple Guests: A Stakeholder Roundtable

May 31, 2022 10:58 - 1 hour - 167 MB

In this lively debate pertaining to all things multiple myeloma, Chadi hosts three guests with varying positions and viewpoints: Vincent Rajkumar, MD, Mayo Clinic; Manni Mohyuddin, MD, Huntsman Cancer Institute; and Cindy Chmielewski (@myelomateacher), patient research advocate. The group discuss the burning unanswered questions in multiple myeloma research and treatment – including problems related to clinical trial funding and design, control arms and “bad” trials, global disparities and dr...

Patient Voice on Social Media: A Survivor Story

May 24, 2022 09:54 - 55 minutes - 102 MB

Katie Coleman, a software engineer, joins the show to share her inspiring story of being diagnosed with a rare stage 4 kidney cancer at the end of 2020 and her journey through survivorship to the present day. Katie highlights the anxiety and guilt she experienced when moving through urgent care and the ER during the height of the pandemic, the struggles of not having family allowed in the room during her visits with oncologists or visits at home, the occurrences that led to eventual surgical ...

Radiation Oncology: The Past, Present, and Future

May 17, 2022 11:05 - 1 hour - 128 MB

Ralph Weichselbaum, MD, the Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology at the University of Chicago, is the guest of honor on today’s show focusing on radiation oncology as a discipline: the changes that have occurred over the years, the state of the field today, and how the field projects over the next few years. Dr. Weichselbaum highlights the malignancies that are poised for improvements in radiation outcomes in the coming years, how little attentio...

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