Surrogate Endpoints in Solid and Liquid Tumors
Healthcare Unfiltered
English - November 29, 2022 11:48 - 1 hour - 127 MB - ★★★★★ - 125 ratingsScience Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Brothers Rakesh Popat, PhD, multiple myeloma expert, and Sanjay Popat, PhD, thoracic oncologist, join the show for a special discourse on surrogate endpoints and patient benefit. The conversation fluctuates between the “assumption” that surrogate endpoints translate to better survival; breakdowns of the utility and association with overall survival of PFS, ORR, and MRD in the latest literature; reimbursement intricacies and issues surrounding surrogate endpoint criteria; and the need for stronger confirmatory trials after accelerated approvals, along with plenty more important points for consideration.
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