Hosted by Ralph Weichselbaum, MD, Chair of the Department of Radiation and Cellular Oncology, University of Chicago, this episode tackles the burgeoning world of radiopharmaceuticals and features two radiation oncologists: Jeff Michalski, MD, MBA, Washington University in St. Louis and president of ASTRO, and Freddy Escorcia, MD, PhD, National Cancer Institute and National Institutes of Health. They kick it off by giving background context on isotope therapy and the current data for these therapies in different malignancies, including an update into peptides and SBRT; provide commentary on how randomized controlled trials account for the complexities of radiopharmaceuticals in their design (especially pertaining to selection criteria and dosage); and share how a radiation department is structured and staffed to account for all patient needs, including a push for a novel patient-centered approach that involves the nuclear medicine department.

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