Healthcare Unfiltered
184 episodes - English - Latest episode: 10 days ago - ★★★★★ - 125 ratingsHealthcare Unfiltered is an honest, raw, timely podcast tackling any and all topics in healthcare that affect stakeholders. Dr. Chadi Nabhan uses his dynamic conversational skills to challenge his guests to address controversial and important topics. He also brings on world renowned experts to discuss clinical advances in medicine.
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Episodes
Patient Voice on Social Media: A Survivor Story
May 24, 2022 09:54 - 55 minutes - 102 MBKatie Coleman, a software engineer, joins the show to share her inspiring story of being diagnosed with a rare stage 4 kidney cancer at the end of 2020 and her journey through survivorship to the present day. Katie highlights the anxiety and guilt she experienced when moving through urgent care and the ER during the height of the pandemic, the struggles of not having family allowed in the room during her visits with oncologists or visits at home, the occurrences that led to eventual surgical ...
Radiation Oncology: The Past, Present, and Future
May 17, 2022 11:05 - 1 hour - 128 MBRalph Weichselbaum, MD, the Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology at the University of Chicago, is the guest of honor on today’s show focusing on radiation oncology as a discipline: the changes that have occurred over the years, the state of the field today, and how the field projects over the next few years. Dr. Weichselbaum highlights the malignancies that are poised for improvements in radiation outcomes in the coming years, how little attentio...
Collider Bias: What Is It and Why We Should Care
May 10, 2022 10:56 - 45 minutes - 82.9 MBChadi hosts Lars Andersen, MD, MPH, PhD, DMSc, Aarhus University Hospital (Denmark), to discuss an interesting, relatively unknown concept he recently explored in JAMA Guide to Statistics and Methods. Dr. Andersen introduces us to “collider bias” in research design and statistical analysis. He utilizes a few common examples to illustrate how collider bias can affect our interpretation of data, how it differs from confounding and information bias, and rates the quality of COVID-19 research wit...
AML and MDS: Unprecedented Progress
May 03, 2022 11:10 - 1 hour - 135 MBAmer Zeidan, MBBS (@Dr_AmerZeidan), MHS, associate professor of medicine, Yale University School of Medicine, joins the show to cover the latest exciting updates in the treatment landscapes for acute myeloid leukemia and myelodysplasia. The duo discuss the etiology of both malignancies, the intricacies of defining and diagnosing MDS, how patients become classified as either lower-risk or higher-risk MDS and the survival rates of both, concerns and consequences with iron overload during blood ...
A Convo with a Provocative Hematologist
April 26, 2022 10:38 - 1 hour - 127 MBA familiar animated, jovial, Twitter-famed hematologist makes his return to the show to break down all of the most impactful hematology research of the past year, including what’s moving the needle in the CAR-T, DLBCL, non-Hodgkin lymphomas, Hodgkin lymphoma, AML, transplant, and multiple myeloma spaces. Who could the guest of honor be? Tune in to find out. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltere...
Updates from the Community Oncology Alliance with Kashyap Patel
April 19, 2022 11:06 - 47 minutes - 86.2 MBChadi’s guest Kashyap Patel (@KashyappatelMd), MD, president of the Community Oncology Alliance (COA), joins the show to give an update on the current initiatives and state of COA and community oncology as a whole. He chronicles his journey to becoming a medical oncologist at a small community center outside of Charlotte (SC) and how he became aware of the pain points of community oncology in the U.S. The conversation moved into the history and initial aim of COA to help community practices p...
CRISPR: The Healthcare Technology of the Future
April 12, 2022 10:59 - 1 hour - 110 MBSamarth Kulkarni, PhD, CEO of CRISPR Therapeutics, joins the show to chronicle his journey to CRISPR Therapeutics and to break down the ins-and-outs of the technology. He begins by sharing the evolution of CRISPR as a “molecular barcode” and its first viable indication; how he “bets” the technology will have a major footprint in the cancer, diabetes, and cardiovascular disease treatment landscape; shares strategies for shortening the potential time to market for some of the therapies; explain...
RCTs Under the Microscope with Vincent Rajkumar
April 05, 2022 11:03 - 1 hour - 117 MBRecurring guest Vincent Rajkumar (@VincentRK), MD, Mayo Clinic, provides his input on the complexities of randomized controlled trials. The conversation covers the ability of fellowship programs to train fellows in the nuances of clinical trials, how funding is divvied up for different kinds of trials, how trial design is often influenced by expected time for the new drug to get to the market, when the risk is worth taking with the accelerated approval pathway, how to reconcile study designs ...
Leadership and Entrepreneurship with Samer Saab
March 29, 2022 10:57 - 1 hour - 112 MBChadi shifts gears this week to sit down with a renowned business leader: Samer Saab, founder and CEO of the experience management solution company Explorance. Samer sheds light on the challenges of starting and running a successful business, especially during a once-in-a-century pandemic, and the services Explorance offers. The Great Resignation, surveys given to healthcare workers, burnout, immigrant struggles, transparency and flexibility with employees, balancing personal lives with busin...
Updates on GU Cancer Advancements with Rana McKay
March 22, 2022 11:00 - 1 hour - 124 MBRana McKay (@DrRanaMcKay), MD, genitourinary oncologist at UC San Diego, joins the show to recap the clinically relevant research presented at the ASCO GU meeting. She begins with a breakdown of the ARASENS, PROpel, and MAGNITUDE trials for prostate cancer; moves to TROPHY-U-01, EV-103, and ATLANTIS trials for urothelial cancer; hits on KEYNOTE-564 for kidney cancer; and names a few other studies along the way that could move the needle in genitourinary cancers in the near future. *Plus – a s...
The Ketogenic Saga Continues with Nicholas Norwitz and David Feldman
March 15, 2022 10:46 - 1 hour - 115 MBContinuing the ketogenic discussion, Chadi hosts Nick Norwitz (@nicknorwitz), PhD, Harvard Medical School, and welcomes back Dave Feldman (@DaveKeto), senior software engineer and entrepreneur, to discuss their recently authored paper “Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a ‘Lean Mass Hyper-Responder’ Phenotype.” The trio discuss the inspiration for the paper, the methodology and survey questions, results and take-home messages, and the broad range of rea...
The Enigma of the Pathology Profession with Sanam Loghavi
March 08, 2022 12:08 - 1 hour - 112 MBSanam Loghavi (@sanamloghavi), MD, hematopathologist and molecular pathologist at the University of Texas MD Anderson Center, provides a clear picture of pathology as a specialty in this informative episode. Dr. Loghavi argues that medical school curriculum falls short in including pathology as a legitimate specialty for students to pursue, credits and discredits the preconceived notions about what pathology is all about, shares what differentiates good pathologists and exceptional pathologis...
Paul Offit: Making Sense of All of Your Vaccine Questions
March 01, 2022 11:58 - 55 minutes - 102 MBChadi hosts a very renowned, high profile guest – one of the leading vaccine experts in the world and the man co-credited with developing the rotavirus vaccine: Paul Offit (@DrPaulOffit), MD, Director of the Vaccine Education Center and Professor of Pediatrics, Children’s Hospital of Philadelphia. Dr. Offit tackles the hard-hitting questions on everyone’s minds: whether public health policy decisions should be made based on randomized controlled trials during a pandemic, what went into the FD...
Vaccine Hesitancy and Cognitive Bias with Tara Haelle
February 22, 2022 11:55 - 1 hour - 132 MBTara Haella (@tarahaelle), independent science/health journalist, joins the show to discuss her reporting on vaccine hesitancy long before the pandemic (the “trenches of the mommy wars”), how this previous work aligns with today’s COVID vaccine hesitancy, and how cognitive bias plays a substantial part in our individual feelings toward vaccines. Tara explains the longstanding history of vaccine hesitancy, how she came to initially distrust the CDC, how vaccine hesitancy was likely exacerbated...
Walking America and the World with Chris Arnade
February 15, 2022 12:04 - 1 hour - 142 MBChris Arnade (@Chris_arnade), long-time writer and author of “Dignity: Seeking Respect in Back Row America,” joins the show to discuss his recent experience walking America and how his views on politics and the COVID-19 response have changed as a result. Chris shares his unique upbringing and professional background, ways in which he satisfied his early interest in long walks and what he made of these walks, and how this interest developed into touring the U.S. and photographing the people he...
Noha Baz: The Journey of a True Healer
February 08, 2022 11:55 - 1 hour - 161 MBChadi hosts a truly inspiring pediatrician, author, philanthropist, humanitarian, and self-described “healer”: Noha Baz. Dr. Baz opens up about her unique childhood beginning in France and moving to Lebanon, some harrowing stories about young patients being refused care because of lack of money to pay for treatment, her eventual founding of “Les Petits Soleils” in 1997 to provide medical care for children living in Lebanon not benefiting from health coverage, maintaining her focus despite pol...
Criticism and Credence to Medical Writing with Marielle Fares and Tom Lang
February 01, 2022 11:58 - 1 hour - 115 MBChadi welcomes two experienced medical writers, Marielle Fares and Tom Lang, to explain what “medical writing” entails and who the intended audience is, the difference between regulatory and medical education writing as well as patient education and scientific publications, how medical projects come in and what types of instructions and materials medical writers are given, the ins-and-outs of the revision process, what it means when medical writers are listed in the acknowledgments of publish...
Studying and Managing Rare Diseases with Naveen Pemmaraju
January 25, 2022 11:59 - 59 minutes - 109 MBNaveen Pemmaraju (@doctorpemm), MD, department of leukemia, University of Texas MD Anderson Center, joins the show to discuss how researchers approach the investigation of rare diseases. Chadi and Dr. Pemmaraju break down the latter’s distinguished work in blastic plasmacytoid dendritic cell neoplasm (BPDCN)—a rare, aggressive hematologic cancer—as well as other rare and orphan diseases. Context for the rare and orphan disease drug development pathway, granular classification for malignancies...
FDA Accelerated Approvals and COI Phenomenons With Bishal Gyawali
January 18, 2022 12:00 - 58 minutes - 106 MBChadi welcomes back Bishal Gyawali (@oncology_bg), MD, PhD, Queen’s University Cancer Research Institute (Canada), to the show to discuss the history of the FDA’s accelerated approval regulatory pathway, how it is sometimes abused, how low-level surrogate endpoints are being used for approval, what happens (and what should happen) when confirmatory trials do not confirm clinical benefit for drugs approved through this pathway, how conflicts of interest may impact some regulatory decisions, an...
Is CAR-T Therapy Superior to ASCT for Relapsed/Refractory DLBCL?
January 11, 2022 11:58 - 1 hour - 121 MBContinuing his ASH Annual Meeting coverage, Chadi invites Matt Maurer (@MaurerStats), MS, principal biostatistician, Mayo Clinic, and Alan Skarbnik (@ASkarbnik), MD, director of the lymphoma and CLL program, Novant Health (Charlotte, NC), to review the three prominent CAR-T studies in relapsed/refractory DLBCL presented at the meeting. Why were the results divergent and what does this mean for CAR-T’s utility in this setting? The trio break down the ins-and-outs of the trials – both from a st...
Will POLARIX Finally Spell Doom for R-CHOP?
January 04, 2022 12:01 - 59 minutes - 108 MBChadi invites a trio of lymphoma experts to weigh the importance of the POLARIX trial – which was presented at the ASH Annual Meeting and looked at frontline therapy for patients with DLBCL. Matthew Matasar, MD, Memorial Sloan Kettering Cancer Center, co-authored publication of the POLARIX study “Polatuzumab Vedotin in Previously Untreated Diffuse Large B-Cell Lymphoma” in the New England Journal of Medicine and defends the its results with guests Liz Brem, MD, UC Irvine, and Daniel Landsburg...
Masking Children in School: Debunking the Science
December 28, 2021 12:01 - 1 hour - 124 MBDavid Zweig (@davidzweig), published author and science journalist based in New York, joins the show to tackle one specific topic pertaining to the COVID-19 pandemic: mask mandates for children in schools. David’s article “The CDC’s Flawed Case for Wearing Masks in School” was published in The Atlantic early this month and spotlights the “very shaky science” propped up by the CDC that has compelled many schools throughout the US to institute mask mandates for their students. Chadi and David a...
Omicron, Boosters, Vaccines, Myocarditis, and More With Emily Landon
December 21, 2021 11:57 - 1 hour - 138 MBEmily Landon, MD, Executive Medical Director, Infection Prevention and Control, University of Chicago, makes her long-awaited return to the show to provide an update on the status of COVID-19 in the US. Chadi and Dr. Landon discuss the proportion of people in America that have gotten their vaccine and booster, how Omicron has come along so quickly as an “escape” variant, how effective the vaccines are against contracting and fighting Omicron, whether vaccine mandates for healthcare workers ar...
Training, Immigration, and Illness With Samer Al Hadidi
December 14, 2021 11:55 - 46 minutes - 85.4 MBSamer Al Hadidi (@HadidiSamer), MD, assistant professor in the multiple myeloma program, University of Arkansas, shares his own human experience of receiving an unfortunate diagnosis as an immigrant going through residency and through fellowship, all while dealing with the loss of a close relative. Dr. Al Hadidi recounts the dilemma he had as an immigrant in the US on a visa and deciding whether to prioritize his health or his medical training, the way things escalated while progressing throu...
Real-World Evidence vs Clinical Trials
December 07, 2021 12:01 - 1 hour - 147 MBTo debate the utility and appropriateness of real-world evidence against clinical trials for treating patients with hematologic malignancies, Chadi welcomes back Aaron Goodman (@AaronGoodman33), MD, hematologist, University of California San Diego, and Alan Skarbnik (@ASkarbnik), MD, director of the lymphoma and CLL program, Novant Health (Charlotte, NC), as well as invites first-time guest Liz Brem (@DrLizBrem), MD, assistant clinical professor of hematology, UC Irvine. Can RCT designers eve...
All Things Hodgkin Lymphoma With Graham Collins
November 30, 2021 11:54 - 59 minutes - 108 MBChadi hosts Graham Collins (@graham74GC), MBBS, MA, MRCP, FRCPath, DPhil, hematology consultant in the UK, for a broad discussion aimed to simplify an often complicated disease: Hodgkin lymphoma. The duo talk about early-stage disease categorizing, treatment considerations for each stage, reasonable clinical trial endpoints of practice-changing potential, adverse effects resulting from intensive treatments, notable clinical trials and novel treatment approaches, and programs for young adult s...
The Diet and Cholesterol Debate With Dave Feldman and Ethan Weiss
November 23, 2021 11:53 - 1 hour - 182 MBChadi re-invites Dave Feldman (@DaveKeto), senior software engineer and entrepreneur, and Ethan Weiss (@ethanjweiss), MD, cardiologist at UC San Francisco, to rehash a Twitter argument on secondary prevention for heart attacks for patients with high LDL. Should patients receive statins or should they not? What does the data show and where is the controversy, if any? How does diet play a role? What about the infamous KETO diet? The guests discuss a couple of realistic hypothetical scenarios wi...
A Journey Through Lung Cancer History With Govindan Ramaswamy
November 16, 2021 11:56 - 59 minutes - 110 MBRamaswamy Govindan, MD, Anheuser Busch Endowed Chair in Medical Oncology, Washington University School of Medicine in St. Louis, provides the condensed oral history of thoracic oncology – dating from the late 1990s to the present day. Chadi and Dr. Govindan discuss how stage III chemoradiation and PET scans were new strategies before the turn of the century, the introduction of gefitinib as a pivotal moment in the treatment paradigm, the doors opening for EGFR inhibitors, the discovery of ALK...
Committed: The Trials and Tribulations of Psychiatry Training
November 09, 2021 11:56 - 44 minutes - 81.3 MBAdam Stern (@AdamPhilipStern), MD, neuropsychiatrist and assistant professor of psychiatry, Harvard Medical School, joins the show to discuss his book “Committed: Dispatches from a Psychiatrist in Training” and the struggles that psychiatry trainees face today. Dr. Stern hits on an unexpected diagnosis he was given three years ago, dealing with imposter syndrome, the cruelty of survival rates when given to individual patients, anecdotes in the book that highlight the nuances of psychiatry tra...
Blockchain and Decentralized Data: The Future of Healthcare
November 02, 2021 10:56 - 50 minutes - 92.4 MBLeah Houston (@LeahHoustonMD), MD, an emergency physician and founder of HPEC (@HPECid) as well as Evercred, explains blockchain as a decentralizer of physician and patient data and how it will be applied ubiquitously across the healthcare system. Dr. Houston shares and makes the case for how blockchain stores medical data and keeps the ownership in the hands of physicians, offers a solution to issuing and maintaining digital credentials for healthcare professionals, and highlights how physic...
The Theranos Debacle With Ben Mazer
October 26, 2021 10:56 - 53 minutes - 98.3 MBBen Mazer (@BenMazer), MD, anatomic and clinical pathologist at Yale New Haven Hospital, joins Chadi to recap the rise and fall of the now infamous Theranos – a private lifestyle and healthcare startup company that claimed to have innovative, revolutionary blood testing technology that was ultimately proven ineffective. Dr. Mazer explains how Elizabeth Holmes, the founder of the company, allegedly engaged in a multi-million dollar scheme to defraud investors, doctors, and patients. Fast forwa...
American Healthcare: A Hot Mess
October 19, 2021 10:58 - 56 minutes - 103 MBMarion Mass (@mass_marion), MD, practicing pediatrician and co-founder of Practicing Physicians of America, joins the show to share her unique ideas about how to reduce healthcare costs while simultaneously improving access to care. She describes her “sentinel moment” in which she realized that physicians are no longer the primary medical advocates for their patients and how this led her to founding a grassroots physician organization dedicated to patient advocacy. The conversation takes inte...
The Medical Crisis in Lebanon: Is There a Solution?
October 12, 2021 11:01 - 54 minutes - 99.1 MBFadlo Khouri (@DrFadloKhuri), MD, hematologist and medical oncologist, and president of the American University of Beirut (Lebanon), is asked to join the show after a recent announcement from the University regarding a fuel shortage at its hospital. Dr. Khouri explains how Lebanon’s economic downturn is affecting hospitals – from the inability to supply hospitals with air conditioning to cancer therapies. He also gives a glimpse of a day in the life of the AUB president, how he approaches pol...
Diet, Exercise, and Obesity With Jerry Teixeira
October 05, 2021 10:58 - 1 hour - 133 MBKeeping up with the dietary theme in recent episodes, Chadi hosts Jerry Teixeira (@jerryteixeira), a strength and conditioning expert. He begins with a personal anecdote on how changing his eating habits along with continued regular exercise was necessary to losing weight, divulges exactly what goes into his low-carb diet, shares how alcohol and dessert consumption factors into the diet, explains the benefits of training your muscles to reach temporary muscle failure, breaks down the correlat...
Reverse Engineering the Mystery of Cholesterol With Dave Feldman
September 28, 2021 10:58 - 1 hour - 127 MBChadi is joined by Dave Feldman (@DaveKeto), senior software engineer and entrepreneur, who shares his counterintuitive experience with the ketogenic diet in 2015 and a healthy obsession with the study of lipids and cholesterol that led him to the founding of the “energy model.” Dave breaks down the scientific details of fat cell breakdown in the body, how this process translates in blood tests, and how the “energy model” can be used to elevate one’s health and consumption habits, among a hos...
Debating the Single Payer Model and FDA Regulatory Processes
September 21, 2021 11:08 - 1 hour - 138 MBIn a long overdue appearance, Saurabh Jha (@RogueRad), MD, radiologist in Philadelphia, makes his triumphant return to the show to pick apart the single payer model idea as well as FDA regulatory processes, this time with a worthy adversary: Adam Gaffney (@awgaffney), MD, MPH, pulmonary specialist and health policy researcher at Cambridge Health Alliance/Harvard Medical School. The conversation begins with discussion of a proposed federal single payer system in America, why it could not be mo...
Mid-Career Academic Transitions with Mikkael Sekeres and David Steensma
September 14, 2021 11:02 - 1 hour - 136 MBMikkael Sekeres (@MikkaelSekeres), MD, chief of the division of hematology at the University of Miami Sylvester Comprehensive Cancer Center, and David Steensma (@DavidSteensma), MD, global hematology head at Novartis, share their recent experiences undergoing career transitions. The physicians dive into a discussion on how often fellowships are given to candidates who are pursuing academic careers, how and why the decisions were made to leave one institution for another (or an institution for...
Challenges for Young Academicians and Trainees With Sonikpreet Aulakh
September 07, 2021 13:40 - 51 minutes - 94.8 MBSonikpreet Aulakh (@SonikpreetA), MD, assistant professor of medicine at West Virginia University, provides valuable perspective on the transition into the academic world just two years after her fellowship. Dr. Aulakh sheds light on the experience and details of applying for jobs post-fellowship, what types of challenges she may face as a new faculty member, struggles she may encounter as an immigrant and a woman in applying for residency and faculty positions, and plenty more.
The FDA: The Gift that Keeps on Giving
August 31, 2021 10:56 - 55 minutes - 102 MBAaron Mitchell (@TheWonkologist), MD, MPH, medical oncologist and health outcomes researcher at Memorial Sloan Kettering Cancer Center, comes on to discuss the shortcomings and pitfalls of the regulatory processes at the FDA, optimal trial endpoints that provide the strongest evidence for approval, whether the accelerated approval process is enforced as it is written, what power any advisory panel really has when it comes to FDA approvals, and so many more pain points today.
Revisiting COVID-19: Variants and Vaccines
August 24, 2021 11:06 - 1 hour - 119 MBChadi is rejoined by Priya Sampathkumar (@PSampathkumarMD), MD, infectious disease specialist and hospital epidemiologist, Mayo Clinic, to provide a state of affairs for the current COVID-19 situation in America, including why the country has failed to get more of its people vaccinated, why myocarditis has been a frequent side effects in some people, why the delta variant and other future variants come about, whether booster shots should be administered to healthy individuals and those who ha...
A Precise Depiction of Precision Medicine
August 17, 2021 11:00 - 1 hour - 114 MBVivek Subbiah, MD, associate professor in the department of investigational cancer therapeutics, MD Anderson, is the world-renowned guest on the show this week to tackle the world of precision medicine in cancer. He begins by explaining how precision medicine is more than simply a “fancier” mechanism of treatment than chemotherapy, why tumor sequencing is important even though there aren’t drugs available for every possible mutation, how much the field has advanced even in the past 10 years, ...
Peripheral T-Cell Lymphoma: Monitor or Transplantation?
August 10, 2021 11:05 - 57 minutes - 105 MBFor another lively debate, Chadi brings on two lymphoma experts to talk about what to do with peripheral T-cell lymphoma (PTCL) patients after an achieved remission: Barbara Pro (@bpromd), MD, Northwestern University, and Mehdi Hamadani (@MediHumdani), MD, Medical College of Wisconsin. The two doctors share how they counsel and treat patients in uncertain situations, including the “right” circumstances to watch-and-wait, autologous transplant, allogeneic transplant, or maintenance chemotherapy.
Smoldering Multiple Myeloma: To Treat or Not to Treat?
August 03, 2021 12:46 - 1 hour - 114 MBChadi welcomes back Rafael Fonseca, (@Rfonsi1), MD, interim director of Mayo Clinic Cancer Center, and Aaron Goodman (@AaronGoodman33), MD, hematologist, University of California San Diego, to debate whether smoldering multiple myeloma should be treated. They begin by agreeing on a definition of the disease, listing patient characteristics that may warrant consideration for early intervention, and stating the importance of improving the ability to predict progressing disease. The trio then de...
Docs Who Rock
July 27, 2021 11:14 - 1 hour - 146 MBIs it a coincidence that many clinicians are talented musicians? These doctors don’t believe so! In this exclusive roundtable pow-wow, Chadi hosts a range of crafty and passionate oncologists that share a similar dedication to music. Conversations on musical inspirations and favorite artists are interwoven with music samples and personal anecdotes in this truly lighthearted, uninhibited jam session like you’ve never heard.
The Whistleblower Who Changed Everything: Nancy Olivieri’s Story
July 20, 2021 11:09 - 59 minutes - 109 MBIn this captivating episode, Chadi shares the microphone with Nancy Olivieri (@DrNancyOlivieri), MD, professor of medicine, pediatrics, and public health science at the University of Toronto, to recount her famous clash with a pharmaceutical company (among other entities) that tried to silence her for reporting on adverse effects related to an experimental drug. Dr. Olivieri became famous for raising doubts about a drug that was being studied to treat patients with thalassemia. In great and j...
R-CHOP versus DA-EPOCH-R for Double-Hit Lymphoma
July 13, 2021 11:13 - 1 hour - 122 MBAlan Skarbnik (@ASkarbnik), MD, director of the lymphoma and CLL program, Novant Health (Charlotte, NC), and Aaron Goodman (@AaronGoodman33), MD, hematologist, University of California San Diego, join the show for a long-awaited debate: treating double-hit lymphoma with R-CHOP vs dose-adjusted (DA)-EPOCH-R. The conversation gets testy when the trio describe double-hit lymphoma in terms of histology and phenotype, the limitations of retrospective analyses when it comes to establishing a standa...
Updates on NET and Diversity Research With Pamela Kunz
July 06, 2021 10:59 - 54 minutes - 99.9 MBTo tackle the complicated world of neuroendocrine tumors (NETs), Chadi is joined by Pamela Kunz (@PamelaKunzMD), MD, Director of the Center for GI Cancers at Yale Cancer Center; as well as the Vice Chief of Diversity, Equity, and Inclusion for medical oncology at Yale Cancer Center. Dr. Kunz begins by shedding light on potential reasons for higher incidence of NETs in the past three decades and the boom of FDA approvals in the last decade, as well as the latest therapies and clinical trials w...
Press Releases, Pre-Prints, Abstracts, and Papers: Reviewing the Peer-Review Process
June 29, 2021 11:18 - 49 minutes - 91.4 MBVincent Rajkumar (@VincentRK), MD, Mayo Clinic, and Editor-in-Chief of Blood Cancer Journal, rejoins the show to answer some critically important questions related to medical publications and information reliability in the pandemic and post-pandemic world. As a consumer of medical news, which sources of information should you take seriously? Should you ignore press releases and pre-prints in favor of abstracts or papers? Should peer-reviewed literature be your only source of reliable informat...
What to Consider When Considering the Keto Diet
June 22, 2021 11:00 - 56 minutes - 103 MBChadi dives into the world of nutrition and dieting with Kevin Bass, MD, PhD student in Texas; Ethan Weiss, MD, cardiologist; and Aaron Goodman, MD, hematologist and current subscriber to the Ketogenic diet. The groups begins with a history of the “Keto” diet and how it has transformed into a popular diet for weight loss, what goes into the traditional Keto diet and how to do it effectively, controversy surrounding the diet and whether it is associated with adverse health effects, reasons to ...
An Update on the COVID Situation in India
June 15, 2021 10:58 - 50 minutes - 93.3 MBTo provide an update on the COVID spike and response in India over the past 6 weeks since Chadi’s previous episode, Aju Mathew (@ajumathew_), MD, oncologist practicing in southern India, joins the show. Dr. Mathew begins by describing the tradeoffs of moving home to practice in India while leaving his academic career behind in the US, offers critical remarks on India’s government use of resources to combat COVID up to and during the “tsunami,” shares how vaccine hesitancy around the world ble...