Science Magazine Podcast
836 episodes - English - Latest episode: 2 days ago - ★★★★ - 3 ratingsWeekly podcasts from Science Magazine, the world's leading journal of original scientific research, global news, and commentary.
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Episodes
Science Signaling Podcast, 20 December 2011
December 20, 2011 00:01 - 16 minutes - 9.45 MBSuppression of conventional T cells by regulatory T cells requires inhibition of calcium signaling downstream of the T cell receptor.
Science Signaling Podcast, 29 November 2011
November 29, 2011 00:01 - 15 minutes - 8.68 MBActivation of the calcium-sensing receptor promotes its trafficking to the cell surface and enhances signaling.
Science Signaling Podcast, 8 November 2011
November 08, 2011 00:01 - 10 minutes - 6.15 MBThe vacuolar ATPase is required for amino acid-mediated activation of mTORC1.
Science Signaling Podcast, 1 November 2011
November 01, 2011 00:01 - 15 minutes - 8.76 MBAn engineered peptide blocks inflammation by inhibiting signaling through a proinflammatory receptor.
Science Signaling Podcast, 25 October 2011
October 25, 2011 00:01 - 16 minutes - 9.42 MBA combination of functional and proteomics approaches identifies regulators of ERK signaling in Drosophila.
Science Signaling Podcast, 11 October 2011
October 11, 2011 00:01 - 12 minutes - 7.22 MBPhosphorylation of the transcription factor Mad determines whether it mediates Wingless or BMP signaling.
Science Signaling Podcast, 4 October 2011
October 04, 2011 00:01 - 15 minutes - 9.11 MBBy working together, cells can overcome the loss of information as it flows through a signaling network.
Science Signaling Podcast, 20 September 2011
September 20, 2011 00:01 - 13 minutes - 7.9 MBActivation of the small GTPase Rho downstream of a chemokine receptor is required for metastasis of some breast cancer cells.
Science Signaling Podcast, 13 September 2011
September 13, 2011 00:01 - 15 minutes - 9.1 MBArginine methylation of RAF determines the specificity of the biological response to growth factors that activate the same signaling cascade.
Science Signaling Podcast, 6 September 2011
September 06, 2011 00:01 - 16 minutes - 9.24 MBActivating integrin signaling may be an effective strategy for developing therapeutics to reduce leukocyte recruitment during inflammation.
Science Signaling Podcast, 23 August 2011
August 23, 2011 00:01 - 10 minutes - 6.29 MBβ2 subunit-containing nicotinic acetylcholine receptors in the prefrontal cortex are sufficient for acetylcholine-mediated enhancement of attentional focus.
Science Signaling Podcast, 9 August 2011
August 09, 2011 00:01 - 12 minutes - 9.49 MBOpioid receptors stimulated with morphine signal less efficiently than those stimulated with an endogenous opioid peptide.
Science Signaling Podcast, 26 July 2011
July 26, 2011 00:01 - 16 minutes - 7.43 MBA cell-based, high-throughput screen identifies activators and inhibitors of invadopodia formation.
Science Signaling Podcast, 5 July 2011
July 05, 2011 00:01 - 10 minutes - 6.24 MBThe anti-inflammatory effects of chloroquine are mediated by inhibition of the lysosome, which enhances glucocorticoid signaling.
Science Signaling Podcast, 28 June 2011
June 28, 2011 00:01 - 19 minutes - 11.2 MBTwo studies shed light on cell cycle-dependent protein phosphorylation during mitosis in yeast.
Science Signaling Podcast, 14 June 2011
June 14, 2011 00:01 - 13 minutes - 7.52 MBStructural analysis reveals how increasing concentrations of monomeric actin prevent a transcriptional coactivator from promoting expression of target genes.
Science Signaling Podcast, 24 May 2011
May 24, 2011 00:01 - 16 minutes - 9.43 MBRecent research reveals details about the regulation and activity of the Hippo signaling mediator Yap.
Science Signaling Podcast, 3 May 2011
May 03, 2011 00:01 - 15 minutes - 8.64 MBTwo related ligands that activate the same receptor have different effects on immune system stimulation and inflammation.
Science Signaling Podcast, 26 April 2011
April 26, 2011 00:01 - 11 minutes - 6.9 MBA growth factor that antagonizes signaling by tumor necrosis factor α relieves symptoms of inflammatory arthritis.
Science Signaling Podcast, 5 April 2011
April 05, 2011 00:01 - 14 minutes - 8.36 MBThe responsiveness of activating NK cell receptors is determined by the distribution of inhibitory receptors.
Science Signaling Podcast, 29 March 2011
March 29, 2011 00:01 - 12 minutes - 7.29 MBNegative feedback mechanisms fail to limit Src family kinase activity in leukemias driven by the oncoprotein Bcr-Abl.
Science Signaling Podcast, 15 March 2011
March 15, 2011 00:01 - 13 minutes - 8.04 MBA protein required for light sensation also plays a role in thermosensing in the fruit fly.
Science Signaling Podcast, 8 March 2011
March 08, 2011 00:01 - 14 minutes - 8.62 MBMathematical analysis reveals how a graded signal can induce a homogeneous response across a field of cells.
Science Signaling Podcast, 22 February 2011
February 22, 2011 00:01 - 15 minutes - 8.66 MBA transcriptional repressor acts as a gatekeeper to restrict the innate immune response to specific stimuli.
Science Signaling Podcast, 25 January 2011
January 25, 2011 00:01 - 12 minutes - 7.28 MBResearchers discuss recent findings on how mechanical stretch regulates signaling pathways in adipocytes and in hypothalamic neurons.
Science Signaling Podcast, 4 January 2011
January 04, 2011 00:01 - 13 minutes - 7.72 MBChief Scientific Editor Michael Yaffe reviews the past year in Science Signaling.
Science Signaling Podcast, 21 December 2010
December 21, 2010 00:01 - 14 minutes - 8.07 MBTargeted removal of individual enzymes elicits changes throughout the entire network of kinases and phosphatases in yeast.
Science Signaling Podcast, 7 December 2010
December 07, 2010 00:01 - 15 minutes - 8.69 MBOxidative stress induces separation of the catalytic and regulatory portions of the yeast 26S proteasome, enabling the catalytic core to degrade toxic oxidized proteins.
Science Signaling Podcast, 23 November 2010
November 23, 2010 00:01 - 12 minutes - 7.01 MBTargeting interactions between HLA-I and the integrin beta4 subunit is a potential strategy for preventing transplant rejection.
Science Signaling Podcast, 9 November 2010
November 09, 2010 00:01 - 12 minutes - 7.06 MBA nonvesicular, nonsynaptic form of communication between axons and neighboring cells may play a role under normal conditions and in disease.
Science Signaling Podcast, 26 October 2010
October 26, 2010 00:01 - 9 minutes - 5.69 MBDisrupting activity of the guanosine triphosphatase-activating protein ARAP3 is a potential strategy for anti-angiogenic therapy.
Science Signaling Podcast, 5 October 2010
October 05, 2010 00:01 - 11 minutes - 6.62 MBInhibition of Apolipoprotein-E signaling is a potential clinical strategy for enhancing the delivery of neuroprotective drugs to the brain after ischemic stroke.
Science Signaling Podcast, 24 August 2010
August 24, 2010 00:01 - 11 minutes - 5.4 MBA phosphoprotemic approach identifies potential targets for developing combination therapies to treat cancer.
Science Signaling Podcast, 3 August 2010
August 03, 2010 00:01 - 6 minutes - 3.15 MBA virally-encoded G protein-coupled receptor promotes cellular proliferation and vascularization.
Science Signaling Podcast, 20 July 2010
July 20, 2010 00:01 - 10 minutes - 4.67 MBNetwork redundancies lend robustness to the neuronal injury response.
Science Signaling Podcast, 6 July 2010
July 06, 2010 00:01 - 13 minutes - 6.36 MBLateral inhibition in proneuronal clusters in the fruit fly relies on competition between cis and trans Notch signaling.
Science Signaling Podcast, 29 June 2010
June 29, 2010 00:01 - 15 minutes - 7.05 MBAnalysis of TOR signaling pathway evolution may shed light on the early divergence of eukaryotic lineages.
Science Signaling Podcast, 8 June 2010
June 08, 2010 00:01 - 19 minutes - 8.99 MBMechanical stimulation of the angiotensin receptor promotes cell survival by preferentially activating beta-arrestin-dependent signaling.
Science Signaling Podcast, 25 May 2010
May 25, 2010 00:01 - 10 minutes - 4.75 MBThe balance between WNT and FGF signaling influences the mode of bone formation in the skull.
Science Signaling Podcast, 11 May 2010
May 11, 2010 00:01 - 16 minutes - 7.63 MBGenes that affect development of the nematode gonad are implicated in cell invasion and metastasis.
Science Signaling Podcast, 4 May 2010
May 04, 2010 00:01 - 15 minutes - 7.14 MBAmmonia induces autophagy, which may help cancer cells survive stressful conditions.
Science Signaling Podcast, 20 April 2010
April 20, 2010 00:01 - 14 minutes - 8.35 MBIntegrating interactome and genetics data allows researchers to predict adverse drug effects.
Science Signaling Podcast, 30 March 2010
March 30, 2010 00:01 - 16 minutes - 7.59 MBThe tumor suppressor LKB1 not only keeps cell proliferation in check but also modulates cell adhesion.
Science Signaling Podcast, 16 March 2010
March 16, 2010 00:01 - 14 minutes - 6.8 MBReduction of ankyrin-B activity impairs maximal insulin release and is a risk factor for diabetes.
Science Signaling Podcast, 23 February 2010
February 23, 2010 00:01 - 12 minutes - 5.84 MBDying cells release signals that stimulate cellular proliferation in regenerating tissues.
Science Signaling Podcast, 16 February 2010
February 16, 2010 00:01 - 16 minutes - 7.57 MBThe pathogen Porphyromonas gingivalis evades the innate immune system by initiating signaling crosstalk.
Science Signaling Podcast, 02 February 2010
February 02, 2010 00:01 - 13 minutes - 6.35 MBA noncoding RNA competes with DNA for binding to the glucocorticoid receptor.
Science Signaling Podcast, 26 January 2010
January 26, 2010 00:01 - 12 minutes - 5.81 MBA single amino acid substitution in a viral protein is sufficient to attenuate rabies virulence.
Science Signaling Podcast, 05 January 2010
January 05, 2010 00:01 - 12 minutes - 5.7 MBChief Scientific Editor Michael Yaffe reviews the year in Science Signaling.
Science Signaling Podcast, 15 December 2009
December 15, 2009 00:01 - 16 minutes - 7.84 MBInhibiting fatty acid synthesis may be effective in controlling glioblastomas driven by EGFR signaling.