Science Magazine Podcast
836 episodes - English - Latest episode: 3 days ago - ★★★★ - 3 ratingsWeekly podcasts from Science Magazine, the world's leading journal of original scientific research, global news, and commentary.
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Episodes
Science Signaling Podcast, 10 September 2013
September 10, 2013 00:01 - 10 minutes - 6.03 MBKen Irvine and Gongping Sun explain how JNK signaling leads to nuclear accumulation of the transcription factor Yorkie through phosphorylation of an adaptor protein.
Science Signaling Podcast, 27 August 2013
August 27, 2013 00:01 - 13 minutes - 7.6 MBPeixin Yang and Albert Reece discuss the critical role a proapoptotic kinase plays in the development of neural tube defects associated with maternal hyperglycemia.
Science Signaling Podcast, 13 August 2013
August 13, 2013 00:01 - 15 minutes - 8.84 MBDiomedes Logothetis and Rahul Mahajan explain how G proteins activate a potassium channel to slow heart rate.
Science Signaling Podcast, 6 August 2013
August 06, 2013 00:01 - 10 minutes - 5.97 MBDouglas Lauffenburger discusses how amplification of the receptor tyrosine kinase AXL promotes migration of triple negative breast cancer cells.
Science Signaling Podcast, 23 July 2013
July 23, 2013 00:01 - 14 minutes - 8.21 MBDaniel Davis explains how the distribution of an inhibitory receptor on the surface of natural killer cells changes when an activating receptor is engaged.
Science Signaling Podcast, 16 July 2013
July 16, 2013 00:01 - 7 minutes - 4.29 MBPaul DiCorleto explains how nonmuscle myosin limits proinflammatory signaling by tumor necrosis factor receptor 2.
Science Signaling Podcast, 9 July 2013
July 09, 2013 00:01 - 10 minutes - 6.01 MBKeqiang Ye discusses a small molecule inhibitor of the kinase JAK2 that blocks proliferation of glioblastoma cells.
Science Signaling Podcast, 2 July 2013
July 02, 2013 00:01 - 15 minutes - 9.09 MBKari Alitalo discusses experiments that reveal how two related VEGF ligands trigger distinct biological outcomes by binding to the same receptor.
Science Signaling Podcast, 11 June 2013
June 11, 2013 00:01 - 18 minutes - 10.5 MBBrian Button discusses a feedback mechanism for insuring the proper hydration of airway mucus.
Science Signaling Podcast, 28 May 2013
May 28, 2013 00:01 - 16 minutes - 9.33 MBThe tyrosine kinase BMX may act as a global promoter of maximal receptor tyrosine kinase activity.
Science Signaling Podcast, 14 May 2013
May 14, 2013 00:01 - 13 minutes - 7.66 MBA deubiquitinase helps control the inflammatory response.
Science Signaling Podcast, 7 May 2013
May 07, 2013 00:01 - 18 minutes - 10.7 MBCalcium signaling is required for long-term memory in fruit flies.
Science Signaling Podcast, 30 April 2013
April 30, 2013 00:01 - 12 minutes - 7.17 MBThe chemokine scavenging activity of an atypical chemokine receptor requires signaling through β-arrestin.
Science Signaling Podcast, 16 April 2013
April 16, 2013 00:01 - 16 minutes - 9.21 MBAnalysis of VEGF signaling identifies potential therapeutic strategies for treating pathological angiogenesis.
Science Signaling Podcast, 2 April 2013
April 02, 2013 00:01 - 13 minutes - 7.64 MBA multifunctional protein promotes acetylation and activation of the tumor suppressor p53.
Science Signaling Podcast, 19 March 2013
March 19, 2013 00:01 - 13 minutes - 7.93 MBVitamin E promotes dephosphorylation of the kinase Akt to suppress the growth of prostate cancer cells.
Science Signaling Podcast, 12 March 2013
March 12, 2013 00:01 - 18 minutes - 10.8 MBVariability in receptor protein abundance affects the sensitivity of T cells to the cytokines IL-2 and IL-7.
Science Signaling Podcast, 19 February 2013
February 19, 2013 00:01 - 15 minutes - 8.92 MBMale-type gut microbiota are associated with an increase in testosterone that protects mice from developing type 1 diabetes.
Science Signaling Podcast, 12 February 2013
February 12, 2013 00:01 - 13 minutes - 7.97 MBIn addition to mediating the transcriptional response to hypoxia, HIF-1α also inhibits proliferation under oxygen-limiting conditions.
Science Signaling Podcast, 5 February 2013
February 05, 2013 00:01 - 12 minutes - 7.21 MBAn autophagy receptor specifically targets Salmonella for degradation in infected cells.
Science Signaling Podcast, 29 January 2013
January 29, 2013 00:01 - 14 minutes - 8.53 MBVemurafenib induces endoplasmic reticulum stress in melanoma cells.
Science Signaling Podcast, 15 January 2013
January 15, 2013 00:01 - 15 minutes - 8.98 MBIdentification of inflammatory response regulators sheds light on disease.
Science Signaling Podcast, 1 January 2013
January 01, 2013 00:01 - 16 minutes - 9.59 MBB cell receptor clustering determines which kinases are required for signaling.
Science Signaling Podcast, 27 November 2012
November 27, 2012 00:01 - 12 minutes - 7.26 MBA phosphatase implicated in autoiummunity modulates the activities of both effector and regulatory T cells.
Science Signaling Podcast, 20 November 2012
November 20, 2012 00:01 - 22 minutes - 12.1 MBThe 2012 Nobel Prize in Chemistry honors research on the function of G protein–coupled receptors.
Science Signaling Podcast, 6 November 2012
November 06, 2012 00:01 - 14 minutes - 8.21 MBA lipid signaling enzyme promotes the growth, vascularization, and metastasis of tumors in mice.
Science Signaling Podcast, 30 October 2012
October 30, 2012 00:01 - 16 minutes - 9.64 MBMice lacking an inhibitory receptor have defects in the number, size, and function of platelets.
Science Signaling Podcast, 23 October 2012
October 23, 2012 00:01 - 16 minutes - 9.54 MBA growth signal can mediate feedback that reduces cell proliferation and stem cell self-renewal.
Science Signaling Podcast, 9 October 2012
October 09, 2012 00:01 - 13 minutes - 7.57 MBThe neurotrophic factor BDNF has opposite effects on cocaine- and morphine-induced neuroplasticity.
Science Signaling Podcast, 11 September 2012
September 11, 2012 00:01 - 12 minutes - 7.23 MBThe activity of a lipid kinase influences the production of invadopodia by cancer cells.
Science Signaling Podcast, 28 August 2012
August 28, 2012 00:01 - 14 minutes - 8.22 MBA protease can help protect against neurodegeneration by preventing inflammation in microglia.
Science Signaling Podcast, 14 August 2012
August 14, 2012 00:01 - 18 minutes - 10.7 MBGrowth of the male rhinoceros beetle’s horn is more sensitive to insulin signaling than are other body parts.
Science Signaling Podcast, 7 August 2012
August 07, 2012 00:01 - 15 minutes - 9.13 MBDrugs that reduce microtubule density or prevent the production of reactive oxygen species in skeletal muscle might slow the progression of Duchenne muscular dystrophy.
Science Signaling Podcast, 31 July 2012
July 31, 2012 00:01 - 14 minutes - 8.49 MBA scaffolding protein enables clustering of IgG B cell receptors to promote antibody secretion by memory B cells.
Science Signaling Podcast, 24 July 2012
July 24, 2012 00:01 - 14 minutes - 8.61 MBA transcription factor protects the heart from radiation-induced damage.
Science Signaling Podcast, 3 July 2012
July 03, 2012 00:01 - 16 minutes - 9.42 MBStructural analysis reveals how a Wnt binds to its receptor.
Science Signaling Podcast, 26 June 2012
June 26, 2012 00:01 - 19 minutes - 11.2 MBAn inhibitory receptor blocks proliferation of autoreactive T cells to promote tolerance in the periphery.
Science Signaling Podcast, 19 June 2012
June 19, 2012 00:01 - 12 minutes - 7.22 MBModification of a bound lipid modulates the activity of a nuclear receptor.
Science Signaling Podcast, 12 June 2012
June 12, 2012 00:01 - 13 minutes - 7.48 MBRegulated nuclear translocation of a transcription factor maintains lysosomal homeostasis.
Science Signaling Podcast, 22 May 2012
May 22, 2012 00:01 - 11 minutes - 6.55 MBInterferon-β therapy is only effective in treating a mouse model of multiple sclerosis when the disease is dependent upon the NLRP3 inflammasome.
Science Signaling Podcast, 8 May 2012
May 08, 2012 00:01 - 14 minutes - 8.26 MBMaximal blood vessel dilation can be induced by calcium influx through a just few channel molecules in vascular endothelial cells.
Science Signaling Podcast, 1 May 2012
May 01, 2012 00:01 - 14 minutes - 8.18 MBReceptor tyrosine kinases existed in the unicellular ancestors of multicellular animals and underwent diversification in the metazoan lineage.
Science Signaling Podcast, 10 April 2012
April 10, 2012 00:01 - 20 minutes - 11.9 MBNew findings elucidate mechanisms by which astrocytes can modulate neuronal activity.
Science Signaling Podcast, 3 April 2012
April 03, 2012 00:01 - 15 minutes - 8.65 MBRapamycin’s effects on longevity and insulin sensitivity are mediated by different molecular targets.
Science Signaling Podcast, 27 March 2012
March 27, 2012 00:01 - 14 minutes - 8.41 MBRegulated protein synthesis and degradation mediate skeletal muscle homeostasis.
Science Signaling Podcast, 6 March 2012
March 06, 2012 00:01 - 12 minutes - 6.96 MBSignaling from two growth factors converges on the cell cycle inhibitor p57 to regulate proliferation and limit oncogenesis.
Science Signaling Podcast, 14 February 2012
February 14, 2012 00:01 - 15 minutes - 8.9 MBThe protein phosphatase activity of PTEN impairs macrophage phagocytosis of a fungal pathogen by promoting actin depolymerization.
Science Signaling Podcast, 7 February 2012
February 07, 2012 00:01 - 15 minutes - 8.66 MBActivity of the kinase CK2 promotes the generation of intracellular zinc waves by stimulating the zinc channel ZIP7.
Science Signaling Podcast, 31 January 2012
January 31, 2012 00:01 - 16 minutes - 9.57 MBSignaling through PAS kinases bypasses the pro-growth requirement of Tor2 in yeast.
Science Signaling Podcast, 10 January 2012
January 10, 2012 00:01 - 13 minutes - 7.94 MBExploiting crosstalk between signaling pathways may lead to more effective melanoma therapies.