Authentic Biochemistry

Cytoepigenetics XI. The Treg essential linneage specific transcription factor FOXp3 promoter is regionally variably demethylated and acetylated to control Th immunosuppression.DJGPhD.04.Jan.23.

January 04, 2023 23:20 - 30 minutes - 27.8 MB

References Front. Immunol. 2015. 6: 493. Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Epistemological integration into realized metaphysics III. Mensam de phaenomenus and the concept of evidentiary existentialism in research science. DJGPhD.01Jan23.Authentic Biochemistry.

January 02, 2023 00:08 - 29 minutes - 27.5 MB

References Anaximander 6th century B.C. Plato-Timaeous 4th century B.C. Kant 1781 Critique of Pure Reason Basic quantum physics notes Dr Guerra Neuroscience lectures --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoEpigenetics X(A). Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

December 31, 2022 17:46 - 30 minutes - 27.8 MB

References The Journal of Biological Chemistry16/2/2018293: 2422-2437. Anal Cell Pathol (Amst). 2018; 2018: 787.1814 Nature Reviews Drug Discovery. Sep2014, Vol. 13 Issue 9, p673-691 J Cancer Res Clin Oncol. 2018; 144(6): 1065–1077. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoEpigeneticsX. Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

December 31, 2022 00:09 - 29 minutes - 27.7 MB

References J Cancer Res Clin Oncol. 2018; 144(6): 1065–1077 Nature Reviews Drug Discovery. Sep2014, Vol. 13 Issue 9, p673-691 Anal Cell Pathol (Amst). 2018; 2018: 787.1814 The Journal of Biological Chemistry 16/2/2018 293: 2422-2437. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

Diabetes XXV. Obesity linked disruption of adipose mediated endocrine hormone control over fatty acid turnover from TAG leads to T2D in humans. Dr. Daniel J. Guerra. 3April22.Authentic Biochemistry

December 30, 2022 23:18 - 29 minutes - 27.5 MB

References Dr. Guerra lecture materials Progress in Lipid Research Volume 74, April 2019, Pages 145-159 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Abuse Lecture I. EtoH ingestion, while intoxicating redox metabolism is also a membrane lipid -protein interacting agent that corrupts inwardly rectifying K voltage gated channels.

December 30, 2022 23:16 - 30 minutes - 27.8 MB

References Dr Guerra EtOH lectures PNAS November 5, 2013 vol. 110 no. 45 Alcohol, 2017-12-01, Volume 65, Pages 51-62 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoEpigeneticsIX. Promoter/Enhancer proximal and distal epigenetic signatures and transcription factor protein heterogeneity compose gene expression event ontology.DJGPhD.29.12.22.AuthenticBiochem

December 29, 2022 21:32 - 29 minutes - 27.7 MB

References Proc Natl Acad Sci U S A. 2021 Nov 16; 118(46) Nat Rev Mol Cell Biol. 2021 Dec 1; 22(12): 815–833. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

More "mere" epistemology opening a door to metaphysics II. Non-canonical epi-rational and epi-empirical retailoring of understanding and imagination via research scientific endojectification.DJGPhD.

December 25, 2022 02:11 - 24 minutes - 22.9 MB

References Dr. Guerra's ongoing flight into the telos of research science. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoepigeneticsVIII. Protective immunotolerant neonate Th1 inactivity involves IL-12 p35subunit promoter methylation. DJGPhD.23.12.22. Authentic Biochemistry Podcast

December 24, 2022 01:36 - 29 minutes - 27.7 MB

References Trends in Immunology. REVIEW. 2017. VOLUME 38, ISSUE 4, P287-297. J Biomed Sci. 2014 Aug 19;21(1):76. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use VIII. EtOH induced cAMP /CREB associated PKA kinase driven phosphorylation cascade co-opts the TLR4-mediated neuroinflammatory/neurotoxic CNS-microglial axis.DJGPhD.22.12.22.AB.

December 23, 2022 00:08 - 30 minutes - 27.8 MB

References Neural Plasticity. 2019; 2019: 1648736. Molecular Pharmacology May 2017, 91 (5) 451-463. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use VII. EtOH exposure precipitates chromatin methylation associated MCH and chemokine involvement linking arousal, reward and inflammation. DJGPhD.21.12.22 Authentic Biochem.

December 21, 2022 16:53 - 29 minutes - 27.7 MB

References PLoS One. 2011;6(5):e17711 J Neuroinflammation. 2020; 17: 207 Front Neurosci. 2019 Nov 26;13:1280 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Mere Epistemology Knocking on Metaphysics for a late December Evening. I. DJGPhD.21 December 2022 Authentic Biochemistry Podcast

December 21, 2022 03:31 - 21 minutes - 19.7 MB

References Dr Guerra's ideas and concepts concerning the epistemics of research science . Lecture I. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use VI. EtOH associated DNA methylation of neurotransmitter systems opens the door to neurotoxicity and cognitive deficits. DJGPhD.18.12.22b. Authentic Biochemistry Podcast

December 18, 2022 22:57 - 30 minutes - 27.8 MB

References Dr Guerra EtOH lectures Dr Guerra Reward Pathway lectures Biol Psychiatry. 2020 Jan 1; 87(1): 64–73 Biochemistry and Cell Biology. 2019. Volume 97, Number 4.August. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use V. EtOH mediated WNT signaling and PLC mediated IP3/DAG induction of protein kinase and Ca2+ mobilization contribute to aberrant transcription and translation corrupting health.

December 18, 2022 20:13 - 30 minutes - 27.8 MB

References Dr Guerra EtOH lectures Physiol Rev 2016. 96: 1261–1296. Clinical and Molecular Teratology. 2016. Volume 106, Issue 9 Pages 749–760 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use IV. MDH and LDH play essential roles in EtOH mediated corruption of bioenergetics, development, and gene expression during fetal development.DJGPhD.16.12.22 b.Authentic Biochem.

December 17, 2022 00:47 - 29 minutes - 27.7 MB

References Dr Guerra's EtOH lectures Cells. 2020 Sep; 9(9): 2125. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday Ethanol Use III. In utero fetal cardiac muscle development is corrupted by maternal EtOH exposure via metabolic, bioenergetic and epigenetic means involving fatty acid and folate redox poise.

December 16, 2022 19:56 - 30 minutes - 27.8 MB

References Dr. Guerra's EtOH lectures Clinical and Molecular Teratology 2016. Volume 106:749–760 Stat Pearls. Embryology and Gastrulation. NIH 2022. https://www.ncbi.nlm.nih.gov/books/NBK554394/ --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Holiday EtOH Lecture II. Ethanol ingestion permanantly corrupts myelin lipid composition while altering MET and Folate metabolism leading to epigenetic syntactic and semantic chromatin errors.DJGPhD.

December 14, 2022 17:47 - 29 minutes - 27.6 MB

References Clinical and Molecular Teratology Volume 106, Issue 9 September 2016 Pages 749–760 Alcohol, 2017-12-01, Volume 65, Pages 51-62 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Immunoepigenetics VII. MicroRNA mediated feedback control over signalling response toward inflammation.DJGPhD. 10Dec22. Authentic Biochemistry

December 11, 2022 00:44 - 30 minutes - 27.8 MB

References Arthritis Res Ther. 2021; 23: 19. Frontiers in Immunology. November 2014. 21(578):1 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoepigeneticsV!. TLR's and TCR's use membrane lipid raft signal transduction to obtain transcription factor mediated cell fate via epigenetic modification. DJGPhD.09 Dec.22

December 09, 2022 20:00 - 29 minutes - 27.7 MB

References Frontiers in Immunology November 2014. 21(578):1 Clin Epigenetics. 2017; 9: 94 Cancer Cell International September 2020. 20(1):429 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoepigeneticsV. TCR activation and the integration of cell senescence with epigenetic authorship and reading-mediated tumorigenesis. DJGPhD.07Dec22. Authentic Biochemistry

December 07, 2022 22:13 - 29 minutes - 27.7 MB

References Cancer Cell Int. 2022; 22: 272. Cell Mol Life Sci. 2013 Oct;70(20):3753-72 PLoS Biol. 2013 Mar; 11(3): e1001502 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

ImmunoEpigeneticsIV. Membrane lipid raft components dynamically mediate Tcell reception, hippocampal pyrimidal neuron endocytosis, and lung cancer cell mesenchymal to endothelial transition.DJGPhD.

December 05, 2022 16:48 - 29 minutes - 27.3 MB

References Respir Res. 2017 Sep 6;18(1):168 Front Behav Neurosci. 2020; 14: 24 JLR Methods| 2020.Volume 61, ISSUE 11, P1512-1523, November 01 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Immunoepigenetics 3. EtOH abuse interrupts membrane lipid raft -mediated TCR signaling by decreasing the TF NFAT nuclear translocation and IL-2 transcription.DJGPhD.04.DEC.22.Authentic Biochemistry.

December 04, 2022 20:31 - 29 minutes - 27 MB

Reference Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Immunoepigenetics 2. Treg and ILC differentiation and the evolution of lymphocytic response specificity incl. B cell class switch recombination and somatic hypermutation deamination.DJGPhD.2.12.22

December 02, 2022 20:30 - 30 minutes - 27.8 MB

References Advances in Immunology. 2011 v.109.Pp125 Biomed J. 2014 Sep-Oct;37(5):269-83 Alcohol Clin Exp Res. 2011 Aug; 35(8): 1435–1444 Cell Reports 10, 2043–2054, March 31, 2015 Front. Immunol., 28 September 2015 | https://doi.org/10.3389/fimmu.2015.00493 Front. Immunol., 07 January 2021 Sec. T Cell Biology https://doi.org/10.3389/fimmu.2020.609891 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 86/Immunoepigentics1. The complex divergent roles of Inhibitor of DNA (Id) binding proteins in terminal differentiation and disease states. DJGPhD.01.12.22.Authentic Biochemistry

December 02, 2022 02:28 - 30 minutes - 27.8 MB

References Cell Reports Volume 17, Issue 11, 13 December 2016, Pages 2827-2836 Cardiovascular Research, cvac159, https://doi.org/10.1093/cvr/cvac159.Published:27 September 2022 Cancer Med. 2012 Oct; 1(2): 176–186. Nat Immunol. 2011 Nov 6; 12(12): 10 Nat Immunol. 2014 Aug; 15(8): 767–776 Stem Cells. 2007 Feb;25(2):500-10. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 85. EBV latent membrane protein induction of haemopoietic proliferative disease and Id repressor protein transcriptionally mediated terminal differentiation.DJGPhD.30.11.22.

November 30, 2022 23:30 - 29 minutes - 27.7 MB

References Stem Cell Reviews and Reports volume 17, pages 1486–1499 (2021) BMC Cancer. 2008 Dec 19;8:379 Curr Top Microbiol Immunol. 2015;391:119-49. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 84. Isolation of membrane protein using non-ionic detergents exposes the prescence of cellular lipid raft domains. DJGPhD. 29.11.22. Authentic Biochemistry.

November 30, 2022 00:13 - 29 minutes - 27.7 MB

References Methods Mol Biol. 2021; 2268: 1–20 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 83. Countercurrent distribution theory of membrane lipid raft mediated endomebranous sequence ontology. DJGPhD.26.11.22

November 26, 2022 21:26 - 29 minutes - 27.8 MB

Referernces Dr. Guerra's deductive reasoning --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membarne Biochemistry 82. Coda in absentia. Redux of the epistemological lens and the membrane lipid raft resurfaces. Dr. Daniel J. Guerra. 23.11.22. Authentic Biochemistry Podcast

November 23, 2022 20:33 - 29 minutes - 27.7 MB

References Timaeus, Plato Dr Guerra's thoughts and lectures N Engl J Med 2005;353:604-15 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 81. Synopsis. Logical judgment and square of opposition applied to lipids as transcription factors and membrane sequence derivatives respectively. DJGPhD19.11.22.Authentic Bioch

November 19, 2022 21:06 - 29 minutes - 27.8 MB

References Dr Guerra's unpublished writings --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemisty.Steroidogenic endo-nuclear sphingolipid metabolism involving ganglioiside turnover mediates transcription factor de-repression via DAG kinase.DJGPhD.18.11.22.

November 19, 2022 00:52 - 30 minutes - 27.8 MB

References Dr Guerra's lipid lectures Front Pharmacol. 2020; 11: 569802 Biomolecules 2022, 12(10), 1434; https://doi.org/10.3390/biom12101434 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 79. Sphingolipids and cyclic phosphatidic acid control PPAR isoform-mediated gene transcription over lipid metabolism and inflammation. DJGPhD.16.11.22. Authentic Biochemistry

November 16, 2022 20:04 - 29 minutes - 27.6 MB

References Circulation Research. 2008;102:283–294 Neurochemical Research volume 45, pages 972–988 (2020) Biochim Biophys Acta. 2008 Sep; 1781(9): 519–524. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 78. Nuclear sphingolipid metabolism controlling cAMP response element-mediated transcription promoting proinflammation and anti-inflammation temporally and spatially.DJGPhD.

November 15, 2022 21:47 - 29 minutes - 27.6 MB

References Nature Scientific Reports 2017.volume 7, Article number: 18004 Cells 2022, 11(13).https://doi.org/10.3390/cells11132020 European Journal of Endocrinology 2015. (July). 173(4). Front Pharmacol. 2020; 11: 569802. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 77. Membrane lipid mediated IGF-I in contextual expression within discrete organ systems controls an inflammatory valence DJGPhD. 9 November 2022 Authentic Biochemistry

November 10, 2022 01:50 - 29 minutes - 27.5 MB

References Front Aging Neurosci. 2017; 9: 365 J Physiol Biochem. 2017; 73(2): 245–258 Annu Rev Physiol. 2012; 74: 131–151. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 76. Introduction to SubCellular-Distribution Mechanisms and Function of Nuclear-Localized Lipids. DJGPhD.06Nov22b.Authentic Biochemistry Podcast

November 06, 2022 20:02 - 29 minutes - 27.7 MB

References Dr Guerra lecture notes Annu Rev Physiol. 2012; 74: 131–151. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry75. Rational judgment as the epistimological prolegomena to research science:isoprenoid lipid biosynthesis guided event ontologies.DJGPhD.6NOV22.Authentic Biochemistry.

November 06, 2022 19:01 - 30 minutes - 27.8 MB

Dr Guerra's Lecture notes --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 74. ER-Phosphatidylcholine biosynthesis regulates neuritigenesis and the use of logical judgment in research science. DJGPhD. 03Nov22. Authentic Biochemistry

November 03, 2022 19:26 - 29 minutes - 27.7 MB

References PLoS One. 2019 Jan 10;14(1):e0210207 Nature Communications volume 9, Article number: 1784 (2018)) Cell Death & Disease volume 8, page e2897; 2017 Nat Cell Biol. 2013 Apr;15(4):373-84 Dev Neurobiol. 2010 Jul; 70(8): 589–603 J. Lipid Res. (2022) 63(8) 100213 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 73. Pathogenic membrane associated phosphatidylcholine and sphingomyelin metabolism is linked to skeletal and CNS pathology. DJGPhD.02NOV22. Authentic Biochemistry

November 02, 2022 21:25 - 30 minutes - 27.8 MB

References J. Lipid Res. (2022) 63(8) 100213 Front. Cell Dev. Biol., 15 October 2019 Bortlein et al. Cell Death & Disease. 2016. volume 7, page e2488 J. Biol. Chem. 1998;273:14550-14559 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry72. DHEA and the steroidogenic pathways as biochemical prolegomena to logical judgments. Dr. Daniel J. Guerra.29.10.22b.Authentic Biochemistry

October 29, 2022 23:54 - 29 minutes - 27.6 MB

References Dr Guerra's lipid biochemistry lectures Int. J. Mol. Sci. 2019, 20, 4660; doi:10.3390/ijms20194660 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 71. Intracellular-endomembranous cholesterol trafficking and estrogen biosynthesis is under epigenetic control. DJGPhD.29.10.22.Authentic Biochemistry.

October 29, 2022 19:30 - 29 minutes - 27.7 MB

References Dr Guerra's lipid lectures Periodicum Biologorum 2011. 113(1):43-49 Obstet Gynecol Sci 2014. v.57(2) --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 70. Ketogenesis and cholesterologenesis are mediated by mitochondrial bioenergetics and the ER+Peroxisomal metabolism of VLCPUFA's via membrane domain event ontology.DJGPhD

October 27, 2022 21:53 - 29 minutes - 27.7 MB

References J Biol Chem v.298(7); 2022 Jul PMC9207681 Antioxidants (Basel). 2021 Jun 3;10(6):906. Dr Guerra lipid lectures --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 69. Distilled electrochemical potential mediated Inner mitochondrial membrane redox and the introduction to sterol involvement.DJGPhD.27.10.22. Authentic Biochemistry

October 27, 2022 19:06 - 30 minutes - 27.8 MB

Dr. Guerra's Basic Biochemistry Lecture notes --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 68. Elevatum Hypostasis. Dr Daniel J. Guerra. 22.10.22b Authentic Biochemistry

October 22, 2022 23:37 - 29 minutes - 27.7 MB

Necessary and sufficient knowledge eo ipso obtaining the communicated telos. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 67. VDAC oligimerization inhibition can block mitochondria-mediated apoptosis and NLRP3 inflammasome activation. DJGPhD.22.10.22.Authentic Biochemistry.

October 22, 2022 20:28 - 29 minutes - 27.8 MB

References Immunity 2022 551370-1385.e8DOI: (10.1016/j.immuni.2022.06.007 J Biol Chem. 2016 Nov 25; 291(48): 24986–25003. J of Visualized Experiments. 2013; (81): 50966 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 66. Staph aureus infection, autoimmune disease, biliary cholangitis, and neurodegeneration involve NLRP3 Inflammasome activation with core bioenergetic involvement. DJGPhD.

October 21, 2022 01:04 - 29 minutes - 27.7 MB

References Dr Guerra's immunology lecture notes J Vis Exp. 2013; (81): 50966 Front Immunol. 2019; 10: 1309. Infect Immun. 2013 Dec; 81(12): 4478–4489. Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 65. The integration of pro-inflammatory signaling from a plenum of molecular membranous events: The NRLP3 Inflammsome. DJGPhD. 19.10.22. Authentic Biochemistry.

October 20, 2022 00:12 - 29 minutes - 27.5 MB

References Dr Guerra's Immunology lectures Am J Gastroenterol. 2004 Nov;99(11):2147-9. Front Immunol. 2019 Jun 7;10:1309 Nat Rev Gastroenterol Hepatol. 2019 Dec 9 Immunity Volume 55 Issue 8 Pages 1370-1385.e8 (August 2022) DOI: 10.1016/j.immuni.2022.06.007 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 64. Prelude to Biochemical Metaphysics and the Mitochondrial Membrane Damage Response I. Dr. Daniel J. Guerra.18.10.22.Authentic Biochemistry Podcast

October 18, 2022 19:29 - 29 minutes - 27 MB

References Dr. Guerra's lecture notes Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 63. The TCR:APC Chemokine receptor Trigger for Cytokine Stimulation. DJGPhD. 16 Oct 2022 Authentic Biochemistry Podcast

October 17, 2022 00:28 - 29 minutes - 27.6 MB

References Dr Guerra's membrane immune synapse lectures Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion. J Bi...

Membrane Biochemistry 62. The T cell receptor mechanism II. Dr. Daniel J. Guerra. 14.10.22 Authentic Biochemistry

October 15, 2022 00:57 - 29 minutes - 27.6 MB

Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Dr Guerra Membrane lipid lectures --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 61. The Tcell membrane :APC synapse I. Dr Daniel J. Guerra 13.10.22 Authentic Biochemistry

October 13, 2022 19:10 - 29 minutes - 27.1 MB

References Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Seminars in Immunology Volume 13, Issue 2, April 2001, Pages 129-138 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Membrane Biochemistry 60. Human neocortical membrane lipid evolution and the links to cognition,fasting, and neurodegeneration. Dr Daniel J. Guerra. 03Oct2022.Authentic Biochemistry.

October 04, 2022 01:38 - 29 minutes - 27.7 MB

References Dr Guerra's membrane lipid lectures Neuron 2015. Volume 85, Issue 4.Pages 695–702 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Authentic Biochemistry

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