Authentic Biochemistry
765 episodes - English - Latest episode: about 24 hours ago - ★★★★★ - 10 ratingsBecome a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
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Episodes
BioMedical Portrait V. Coda c.13 Small molecule pyrazolo-oxazepine derivitive mediated PFK-1 activation depletes NADPH dependent neutrophil oxidative burst. DJGPhD.07NOV23. Authentic Biochemistry
November 08, 2023 01:09 - 30 minutes - 27.8 MBReferences Cell 2021. 184, 1–15 J Zhejiang Univ Sci B. 2022 Jul 15; 23(7): 607–612. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V.c.12. Is there a compositional-sequential event ontology linking "moonlighting"c-Fos with NOX2 PX domain PIP3 binding?DJGPhD. 6NOV23
November 06, 2023 21:18 - 30 minutes - 27.8 MBReferences Nature Communications 2019. volume 10, Article number: 1528 Adv Exp Med Biol. 2019:1111:1-17. doi10.1007/5584_2018_185. Nature Immunology volume 20, pages559–570 (2019) Biochem J. 2001 Dec 15; 360(Pt 3): 513–530. PNAS 1993. 90: 10952-10956 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V.c.11 The Phosphoglycerolipid metabolome that orchestrates membrane topology and surface chemistry that supports necessary protein association for neutrophil immunoresponses.
November 05, 2023 20:14 - 30 minutes - 27.8 MBReferences Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids2014.Volume 1841, Issue 9, Pages 1241-1246 Guerra-graduate lipid lectures --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V.c.10. Phosphphatidyl inositols and phagosmal genesis in activated neutrophils upon pathogen infection.
November 05, 2023 18:12 - 29 minutes - 27.7 MBReferences J Adv Res. 2018 May; 11: 33–41. Immunol Rev. 2023. Volume314, Issue1 .Special Issue: Neutrophils and Friends.March 2023. Pages 158-180. Biochim Biophys Acta Biomembr.. 2023 Oct;1865(7):184180 Front Cell Dev Biol. 2022; 10: 945749. Tchaikovsky, PI., 1878.Violin Concerto in D major, Opus 35 (TH 59 ; ČW 54). https://youtu.be/2ckqOukGKK8?si=jl9TYFA2pgvtI8um --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitV.c9. Both glycolytic and OPP regulation combine complex allosteric and amphibolic sequalae that may converge on an immune- hyperinflammatory state. DJGPhD.2NOV23.
November 02, 2023 23:01 - 29 minutes - 27.5 MBReferences Guerra 2023-graduate biochemistry lecture canon and marginalia Mol Oral Microbiol. 2019 Apr; 34(2): 27–38. Front Cell Dev Biol. 2022; 10: 945749. Mozart, WA. 1784. Piano Concerto No. 17 in G major, KV. 453 https://youtu.be/iYNbMclI5Ls?si=_P9oK14c_wb98VXG --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V.c8. NOX2 subunitorganization, oxygen availability and phase I discussion of glycolytic allosteric control.DJGPhD.01Nov23
November 01, 2023 19:21 - 30 minutes - 27.8 MBReferences FASEB 2017. Volume 31, Issue2 Pages 663-673 Guerra,DJ. Graduate Biochemistry Lectures Albioni , Thomaseo. 1708. Sonate da chiesa ("op. 4") (for violin and basso continuo), https://youtu.be/IMmjjcfG2c4?si=C4VG-rPWL_Fv7-Xe --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V C.5 Periodontitis-linked CVD. DJGPhD. 30.10.31
November 01, 2023 00:56 - 30 minutes - 27.8 MBReferences Eur J Microbiol Immunol (Bp). 2011 Mar;1(1): 41–58 J Periodontal Res. 2018 Jun; 53(3):403–413. DJGPhD lecture notes --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V. c7. NETs and the combined activities of elastase,NOX2,MPO and IP3 PTEN phosphatase potentiate inflammation-linked pathologies of lung and pancreas. DJGPhD.31.10.23 and
November 01, 2023 00:18 - 29 minutes - 27.8 MBReferences J Zhejiang Univ Sci B. 2022 Jul 15; 23(7): 607–612 Biomaterials. 2020 Apr; 238: 119836. Int J Nanomedicine. 2023;18:5265-5287 Child Ballad 100. 1775. Pentangle. 1972.Willie O' Winsbury https://youtu.be/nwqP_yoszCE?si=C0NH51euOOTlPYn9 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V C.6 P. gingivalis Two Component System assembly and activation mediate infection court involvement in subsequent host vector pathology.DJGPhD. 30.10.23b.
October 30, 2023 23:56 - 30 minutes - 27.8 MBReferences J Pharm Bioallied Sci. 2019 May; 11(Suppl 2):S135–S139. J Oral Microbiol. 2017; 9(1): 1400858 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait Vc4 Two component signal system pathogenic bacterial responses to host immunity and the gigipain cysteine protease opposing serum secretory IgA mediated phagocyte activation.DJGPhD
October 29, 2023 19:35 - 30 minutes - 27.8 MBReferences J Pharm Bioallied Sci. 2019 May; 11(Suppl 2): S135–S139. J Oral Microbiol. 2017; 9(1): 1400858. J Dent Res. 2020 Jun;99(6):644-649. Mozart WA 1782. D major, K. 385. Symphony 35 (Haffner) --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V.c3. The categorical analysis of Neutrophil involvement in multiple pathophysiologies requires cellular signaling to derivatize pleiotropic disease ontologies. DJGPhD.26.10.23
October 27, 2023 01:32 - 29 minutes - 27.6 MBReferences Oral Microbiol Immunol. 2006 April 21 (2):84-92 1647-6017 Gut Microbes. 2022; 14(1): 2073785. Adv Exp Med Biol. 2020:1263:13-23 Bredon, Anne. 1950. Led Zepplin. 1969. https://youtu.be/dZitPJMh60A?si=MnEpM-iemNFWEKE7 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V. The neutrohil oxidative burst and the roles of Phox generating superoxide and peptide arginine deiminase in phagocyte defense against pathogens and contrarion disease promotion.
October 26, 2023 01:30 - 30 minutes - 27.8 MBReferences Blood (2004) 103 (11): 3993–3994 Anticancer Agents Med Chem. 2023;23(3):256-265 Med Hypotheses. 2021 Jan:146:110466. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait V. Introductory alethic unfolding of neutrophil glycolysis associated hyperinflammatory restraint.
October 24, 2023 23:55 - 29 minutes - 27.7 MBReferences Cell. 2021 Aug 19;184(17):4480-4494.e15 Sci Rep. 2019 Mar 5;9(1):3433 Med Hypotheses. 2021 Jan:146:110466. Hayward, J. 1967. Moody Blues. "Tuesday Afternoon" https://youtu.be/jmMPBQ4kYKk?si=X0UyZJFq2AAnKSvJ --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Continuing dialectical event ontology of epistemological requirements for validation of biochemical research. DJGPhD.23.10.23. Authentic Biochemistry Podcast
October 23, 2023 20:58 - 29 minutes - 27.8 MBSend an email to [email protected] with comments. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
All reciprocity in not disinterested so phenomena must be in equilibrium. But phenomena at equilibrium are invisible so reciprocity must be uncertain. DJGPhD.22.10.23. Authentic Biochemistry
October 23, 2023 01:49 - 29 minutes - 27.8 MBVide supra. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. Postcript DJGPhD. 21 October 2023. Authentic Biochemistry Podcast
October 22, 2023 01:19 - 30 minutes - 27.8 MBReferences Cureus. 2022. 14(9): e29696.doi:10.7759/cureus.29696 NMR Biomed. 2021 Feb;34(2):e4448. NMR in Biomedicine. 2023. e4896. ISSN 0952-3480 Nutrients. 2023 May; 15(9): 2029. Mozart, WA. 1791 K 626 Requiem in d minor. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. 13b. Magnetic Resonance Imaging as a non-invasive tool in Neurodegenerative Diseases. DJGPhD.19.10.23 Authentic Biochemistry.
October 19, 2023 18:35 - 30 minutes - 27.8 MBReferences Mol Cell Neurosci. 2012 Jan; 49(1): 44–53 NMR in Biomedicine. 2023. e4896. ISSN 0952-3480 Proc Natl Acad Sci U S A. 2020 Mar 10; 117(10): 5092–5094. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. CODAIII. c13. Microglial and astrocytic CNS local neuronal environment temporality may apprehend FTD stages in the human CNS.DJGPhD.18.10.23. Authentic Biochemistry Podcast
October 18, 2023 23:09 - 30 minutes - 27.8 MBReferences Brain. 2023 Sep 13:awad309. doi: 10.1093/brain/awad309 J Alzheimers Dis. 2016 Feb 26;52(1):43-50. Haydn, FJ. 1796. MISSA IN TEMPORE BELLI https://youtu.be/8_5tgmAwN-E?si=AYzyMMk47b2IUt0Y Send an email to Dr Guerra! [email protected] --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedica; Portrait IV Coda II.c12. Biochemical Concatenations-the spatiotemporal sequences of molecular-cellular events of FTD's from proteinopathies to signalling and antigen recognition. DJGPhD.
October 17, 2023 20:36 - 29 minutes - 27.7 MBReferences Brain. 2023 Sep 13:awad309 McBroom, Amanda. 1970 "the Rose" httBps://youtu.be/cO59ITNCxzk?si=v-qx_2_mPq3zbCYH --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV c11. FTLD-tau is correlated with microglial and astrocytic inflammation and subsequent neural degeneration. DJGPhD. 16.10.23 Authentic Biochemistry.
October 17, 2023 01:45 - 30 minutes - 27.8 MBReferences Front. Immunol., 19 October 2022 Brain. 2023 Sep 13:awad309. doi:10.1093/brain/awad309 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitIV The Frontal Temporal Dementias. Tau and TDP43 proteinopathies as an introduction to the extended pathobiochemical event ontologies. DJGPhD.16.10.23.Authentic Biochemistry Podcast
October 16, 2023 17:46 - 30 minutes - 27.8 MBReferences Schubert, F. 1820. Rosamunde Overture. https://youtu.be/3Pc_LUItWQI?si=ZB3bsrmz3ReiJQdi Brain. 2023 Sep 13:awad309. doi:10.1093/brain/awad309. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. TDP43 is involved in numerous pathologies that connect to the major cellular mechanisms governing DNA RRR, RNA metabolism and protein mediated cell fate. DJGPhD.14.10.23
October 14, 2023 22:02 - 28 minutes - 26.6 MBMol Cell Biol. 2012 Jan;32(1):126-38 Mutat Res. 2013 Jul-Sep;753(1):24-40 Molecular Neurobiology 2022. volume 59, pages 4223–4241 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV c8. Proteolytic processing of cytosolic RNA-bp ,TDP43, associates with CNS neuropathologies while native nuclear translocation is linked to exon shuffling. DJGPhD.12Oct23.
October 12, 2023 21:32 - 29 minutes - 27.7 MBReferences Molecular Neurobiology 2022. volume 59, pages 4223–4241 Hum Genet. 1994 Jan;93(1):67-73 Mol Cell Biol. 2012 Jan;32(1):126-38 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV c8. Prorteolytic processing of cytosolic RNA bp TDP43 associates with CNS neuropathologies while native nuclear translocation is linked to exon shuffling. DJGPhD.12Oct23.
October 12, 2023 21:32 - 29 minutes - 27.7 MBReferences Molecular Neurobiology 2022. volume 59, pages 4223–4241 Hum Genet. 1994 Jan;93(1):67-73 Mol Cell Biol. 2012 Jan;32(1):126-38 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV c7.Progranulin associated frontotemporal lobar degeneration and AD, PD, and LBD, share a TDP-43 proteinopathy linked to mRNA translation. DJGPhD.11OCT23. Authentic Biochemistry
October 12, 2023 00:54 - 30 minutes - 27.8 MBReferences The EMBO Journal (2022)41:e109108 Acta Neuropathol. 2007 Sep;114(3):221-9 Acta Neuropathol.2013 Jul; 126(1): 51–57 Brain 2008. Volume 131, Issue 6, Pages 1416–1432 Lovin Spoonful 1968. "She's a Lady" https://youtu.be/xyFdzevDOHg?si=bLl8FZzfE2SffvO4 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. c6. Proteinopathies in neurodegeneration may be the result of insufficient temporal control over microglial phagocytic and pro-inflammatory molecular event ontologies.DJGPhD
October 10, 2023 23:30 - 29 minutes - 27.2 MBReferences Brooker, G; Fisher, M and Reid, K. Procol Harum 1967. A Whiter Shade of Pale. https://music.youtube.com/watch?v=z0vCwGUZe1I&si=4iY2IY06x74LR2JY The EMBO Journal (2022)41:e109108 PLoS ONE 2013. 8(6): e65646. doi:10.1371/journal.pone.0065646 Molecular Neurodegeneration 2022. volume 17,Article number: 73 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV.c5. Microglial removal of lipoprotein and proteinopathic molecular events must include lysosomal degradation and antigen presentation while supporting signaling and inflammation
October 10, 2023 19:07 - 29 minutes - 27.6 MBReferences Mozart, WA. 1791. Clarinet Concerto in A major, K. 622 https://youtu.be/YT_63UntRJE?si=bXBDcxTxsY1PxJa5 Small GTPases. 2014; 5: e28579 Acta Neuropathol. 2023; 145(6): 749–772 J Immunol. 2000 May 15;164(10):4991-5 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitIVc4. Microglial Rho GTPases equipped with GGylation, palmitoylation and/or phosphorylation obtain a spectrum of biochemical functions in neuropathologies.DJGPhD.8Oct23b. Authentic.
October 08, 2023 23:45 - 29 minutes - 27.7 MBReferences Mol Biol Cell. 2001 Sep; 12(9): 2711–2720. Small GTPases. 2014; 5: e28579. Cells. 2021 Jul 20;10(7):1831. J Investig Med. 2023 Feb;71(2):113-123 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. c3. Two down-regulated microglial polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy distinct LDL binding proteins typically cargo oxy cholesterol.
October 08, 2023 20:54 - 29 minutes - 27.8 MBReferences Sinatra, Frank. timeless. My Way. https://youtu.be/qQzdAsjWGPg?si=TcpVOHDikKyyQdmC Acta Neuropathol. 2023 Jun;145(6):749-772 Signal Transduction and Targeted Therapy 2022. volume 7, Article number: 175 Cardiovascular Research 2007. 74: 526 – 536 J Investig Med. 2023 Feb;71(2):113-123 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitIV.NHD patient fibroblasts used to generate iPSC's differentiated into Induced microglia like cells (iMGLs) pathophenocopied TREM2 mutations and lysosomal malfunctions.DJGPhD.
October 05, 2023 20:14 - 30 minutes - 27.8 MBReferences Neurol Genet. 2018 Jan 18;4(1):e211. J Immunol (2003) 171 (2): 594–599. Acta Neuropathol. 2023; 145(6): 749–772. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait IV. HLA disease including neuropatholgies. The Nasu-Hakola, a.k.a. polycystic lipomembranous osteodysplasia associated TREM2 disease. DJGPhD.04Oct2023.Authentic Biochemistry.
October 05, 2023 00:44 - 30 minutes - 27.8 MBReferences Neurology. 2020 Jul 7; 95(1): e46–e58 Acta Neuropathol. 2023; 145(6): 749–772. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitIIIC13c. Leucocyte and lymphocyte mediated SASP involve a corruption in robust novel immune responses while enhancing chronic autoimmune inflammation in the obese and elderly.DJGPhD
October 02, 2023 23:55 - 29 minutes - 27.6 MBReferences Curr Opin Pharmacol. 2021 Apr; 57: 107–116 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical PortraitIII. c13b.Immune cell metabolic dialectical usurpation of architechtonic control over inflammation and cell fate obtained from senescence and obesity.-linked dyslipidaemia.DJGPhD.
October 01, 2023 01:55 - 29 minutes - 26.9 MBReferences Pisendel Johann G. 1735. Violin Concerto in D major Jun P I.7 https://youtu.be/dvwhXXvFiNg?si=BUb-f5rBncgADinx Curr Opin Pharmacol. 2021 Apr; 57: 107–116 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioiMedical Portrait III. NLRP3 Inflammasome and senescence-associated heterochromatic foci in macrophages, Kuppfer Cells and Liver sinusoidal endothelial cells contibute to liver/adipose disease
September 30, 2023 20:40 - 29 minutes - 26.9 MBReferences Telemann Georg P. 1765. Overture D Major, TWV 55:D18 | Tafelmusik https://youtu.be/8r-IFLtN9x4?si=T2hp65oGT--dTivY Leukemia 2020 volume 34, pages 75–86 Nat Cell Biol. 2019 Mar; 21(3): 397–407 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III.c12. Senescent cells from aging and obesity obtain chronic hyperinflammation of adipose associated leucocyte infiltrates potentiating alternating systemic proliferation or PCD.
September 28, 2023 19:23 - 29 minutes - 27.8 MBReferences Haydn, Michael. 1760. Salve Regina in G MH32. https://youtu.be/u_Xjo5KJ3mg?si=kmKaaBJMvUgs_blX Leukemia 2020. volume 34, pages 75–86 CELL 2006. Volume 126, Issue 3, Pages 503-514 Nat Cell Biol. 2019 Mar; 21(3): 397–407. Curr Opin Pharmacol. 2021 Apr; 57: 107–116. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. AMPK regulation of ACC2 blocks MalCoA inhibition of CPTI allowing for fatty acid beta oxidation thus alleviating adipose obesity-induced macrophage pro-inflammation.DJGPhD.
September 26, 2023 20:45 - 29 minutes - 27.1 MBReferences Saint-Saens. C. 1886. Symphony 3 (avec orgue) OP.78 J Clin Invest. 2011 Dec 1; 121(12):4903–4915 Cell Metab. 2022 Dec 6; 34(12): 2036–2046.e8. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c10. Ribosomal collision frequency is attenuated by ZAK and GCN2 via mutually exclusive signalling events, DJGPhD. 25.9.23. Authentic Biochemistry Podcast
September 26, 2023 00:12 - 29 minutes - 27.1 MBReferences Cell. 2020 Jul 23; 182(2):404–416.e14. Curr Genet. 2021 Feb; 67(1): 19–26. RNA Biol. 2023; 20(1): 737–749. published online 13sept23 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c9. Amino acid deprivation-linked fall of polypeptide synthetic fidelity triggers downstream ribosomal stress response phenomena including kinase mediated cell fate sequalae.
September 23, 2023 19:44 - 29 minutes - 27.8 MBReferences Cell. 2020 Jul 23; 182(2):404–416.e14. Nature Communications 2020. volume 11,3146 Curr Genet. 2021 Feb; 67(1):19–26 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c8. Unique mRNA upstream open reading frames direct both the integrated stress response and rare selective up-regulation of stress-correcting protein synthesis.DJGPhD.21.9.23
September 21, 2023 19:46 - 29 minutes - 27.6 MBReferences Dr Guerra's lectures RNA Biol. 2023; 20(1): 737–749 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III.c.7 Elementary polypeptide synthesis-translation. Lecture 1. DJGPhD.20.9.23.Authentic Biochemistry Podcast.
September 20, 2023 19:53 - 30 minutes - 27.8 MBReference Dr Guerra's lecture notes --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c6. Adipokine and the succinate receptor systems in obese adipose inflammation as regulated by AMPK.DJGPhD.19.9.23. Authentic Biochemistry Podcast
September 20, 2023 01:15 - 29 minutes - 27.4 MBReferences Cream 1968 Wheels of Fire J Neuroinflammation. 2019; 16: 34. Front Immunol. 2019; 10: 345. Cell Metabolism 2023. Volume 35 Issue 4. 601-619.e10 Sci Signal. 2017 Jan 31; 10(464):eaaf7478 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III.c.5. Adipokine mediated adipose inflamation is linked to the hypothalamic control over metabolism and systemic inflammation.DJGPhD.18.9.23.Authentic Biochemistry Podcast
September 18, 2023 23:53 - 29 minutes - 27.7 MBReferences Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55 Int J Biol Sci. 2015; 11(11):1272–1280 Front. Physiol., 01 June 2018 Int. J. Mol. Sci. 2019, 20(6), 1505 Front Immunol. 2023; 14: 1149366 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c.4. Adipose tissue macrophages express galectin binding proteins which alter immunosuppression and polarization;adipokines mediate the inflammatory response. DJGPhD.17.9.23
September 17, 2023 23:42 - 29 minutes - 27.2 MBReferences Luigi Boccherini: Symphony Op. 12 No. 4 in D Minor JCI Insight. 2016 Nov 17; 1(19): e87748 Front Immunol. 2023; 14: 1149366 Adv Biol Regul.2019 Jan;71:41-54. Int. J. Mol. Sci. 2019, 20(6), 1505 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. Immunometabolic disease 3c.Reactive N and O interconversions in obese adipose exacerbate systemic inflammation. 17.9.23. DJGPhD. Authentic Biochemistry Podcast.
September 17, 2023 18:26 - 29 minutes - 27.8 MBReferences Inn Med (Heidelb). 2023 Apr;64(4):313-322. JBC 2001. Volume 276, Issue 31, August. Pages 28799-28805. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. Immunometabolic disease. The obesity-compromised adipose poise to hyperinflammation. DJGPhD. 15.9.23. Authentic Biochemistry.
September 15, 2023 18:02 - 30 minutes - 27.8 MBReferences Schubert, Franz. 1824. March.String Quartet #14 in D minor, D.810 Hypertension. 2002;39:1088–1094 Physiol Rev. 2018 Apr1;98(2):641-665. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait III. c1. Immuno-metabolic disease. Dr. Daniel J. Guerra. 14.9.23. Authentic Biochemistry Podcast.
September 15, 2023 01:12 - 30 minutes - 27.8 MBReferences Schubert. F. 1826. "Ständchen" D.899 Immunol Rev. 2020 May; 295(1): 101–113. Nat Metab. 2022 Sep;4(9):1202-1213 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Biochemical Energetics. Elementary Considerations chapter2. DJGPhD. 13.9.23 Authentic Biochemistry Podcast
September 13, 2023 22:30 - 29 minutes - 27.1 MBReferences Biochemistry lectures: Guerra archives --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Biochemical Energetics I Elementary Considerations. DJGPhD 12Sept23. Authentic Biochemistry Podcast.
September 12, 2023 20:33 - 30 minutes - 27.8 MBReferences Biochem lecture notes --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait II. Hashimoto's Thyroiditis prevalence in women linked to mitochondrial electron transport chain activity, ATP/ADP translocation, and potent autoantibodies to thyroid peroxidase.
September 10, 2023 23:00 - 30 minutes - 27.8 MBReferences Journal of Immunology Research Article ID 8263829 JAMA. 2021 Jun 15; 325(23): 2392–2393. Thyroid. 2014 Feb 1; 24(2): 371–382. Pol Arch Intern Med. 2022 Mar 30; 132(3): 16222. FEBS Letters.1997. (414): 258-262 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
BioMedical Portrait II. c.14. Predominance of Hashimoto's Thyroiditis in Women: is there a link to the decreased expression of TLR7 and the AMPK-alpha/Id3 axis on CD8+TE and Treg activity?
September 10, 2023 19:07 - 29 minutes - 27.8 MBReferences Mozart - Flute and Harp Concerto in C, K. 299 J Immunol Res. 2021; 2021: 8263829. J Immunol. 2022 Jan 1;208(1):155-168 Front. Immunol. 2022.31 March. Sec. Molecular Innate Immunity Volume 13 –202. Cells. 2022 Mar; 11(6): 997 Nature Immunology 2020. volume 21, pages1256–1266. Nature Immunology 2011. 12 (12) 10. --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support