Answers from the Lab
312 episodes - English - Latest episode: 20 days ago -A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.
Homepage Google Podcasts Overcast Castro Pocket Casts RSS feed
Episodes
The Impact of COVID-19 Variants: Dr. Matthew Binnicker
February 04, 2021 07:00 - 16 minutes - 15.4 MBMatthew Binnicker, Ph.D., vice chair of practice for Mayo Clinic's Department of Laboratory Medicine and Pathology, joins William Morice II, M.D., Ph.D., president of Mayo Clinic Laboratories, for this week's "Answers From the Lab" leadership update. In this episode, Dr. Binnicker and Dr. Morice discuss the impact that emerging COVID-19 variants could have on virus testing, vaccine and spread.
MASS-FIX: David Murray, M.D., Ph.D.
February 02, 2021 07:00 - 15 minutes - 14 MB(00:55) Dr. Murray, as we get started today, could you tell us a little bit more about yourself and your background here? (01:50) As you developed this assay, can you just give us a brief overview of it and how it works? (04:07) As you compare those two methods, what are some of the things that you're seeing that are the advantages of this new test? (07:02) When should patients really have this testing, and when are we performing it here at Mayo? (11:54) What do you th...
National COVID-19 Strategy: Dr. Bill Morice
January 28, 2021 07:00 - 10 minutes - 9.54 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the new nationwide strategy that the Biden administration is rolling out to combat COVID-19.
Debunking COVID-19 Vaccine Myths: Dr. Bill Morice
January 21, 2021 07:00 - 15 minutes - 14.7 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., tackle myths surrounding COVID vaccines and talk about where to find reliable vaccine information.
Pancreatic Elastase Test: Puanani Hopson, D.O.
January 19, 2021 07:00 - 12 minutes - 11.2 MB(00:50) Would you be able to tell us a little bit about yourself and your background? (01:26) So would you be able to provide us a brief overview of this assay? (02:16) When thinking about the application of this test, which patients should have this testing, and when should it be performed? (03:09) So after the test has been performed, how are the results used to guide patient care? (04:33) So what alternative testing options are available, and how might those co...
Laboratory Medicine in 2021 and Beyond: Dr. Bill Morice
January 14, 2021 07:00 - 9 minutes - 8.84 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss potential health care reform and other changes that could affect laboratory medicine in U.S. in the coming years.
COVID-19 Variants: Dr. Bill Morice
January 07, 2021 07:00 - 10 minutes - 9.8 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the new COVID-19 variants that are emerging and how those variants could have an impact on the pandemic going forward.
2020 COVID-19 Recap: Dr. Bill Morice
December 31, 2020 07:00 - 17 minutes - 16.5 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., look back at how the COVID-19 pandemic reshaped laboratory medicine throughout 2020.
Dendritic Cell Enumeration Test: Amir Sadighi Akha, M.D., D.Phil.
December 22, 2020 07:00 - 12 minutes - 11.3 MB(00:50) So maybe we'll just start with a simple question. If you could tell us a little bit about you and your background? (01:21) Let's go into, then, the dendritic cell enumeration test. What is this exactly? (03:46) What's innovative or different about this test? (04:56) What would you say is the primary use case of this test? (06:02) So how would you foresee this test being used? (08:06) So do you think that we'll be using this test for perhaps our very si...
Soaring Interest in Health Care Professions: Dr. Bill Morice
December 17, 2020 07:00 - 11 minutes - 10.7 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., talk about the increased interest in health care professions, including those in laboratory medicine, that has been spurred on by the COVID-19 pandemic.
Updated Testing Algorithms for Plasma Cell Proliferative Disorders: Xinjie Xu, Ph.D.
December 15, 2020 07:00 - 8 minutes - 7.8 MBTell us a little bit about your background and about yourself. Give us a brief overview of what are the previous approaches that have been used in the past for multiple myeloma testing. So can you take a moment and talk to me about the new approach and the new algorithm that your laboratory is working on implementing? So how does this new approach really benefit both hospitals across the country that we serve and the patients that they're trying to treat? What else is th...
Debunking Mask Myths: Dr. Bill Morice
December 10, 2020 07:00 - 15 minutes - 14.6 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., debunk common face mask misconceptions in relation to the COVID-19 pandemic.
Paraffin-Embedded Tissue Testing for COVID-19: Anja Roden, M.D.
December 08, 2020 07:00 - 14 minutes - 13.7 MBAnja Roden, M.D., a medical director for Mayo Clinic's Immunohistochemistry Laboratory, joins this episode of the "Answers From the Lab" podcast. Dr. Roden and Bobbi Pritt, M.D., discuss the development and evaluation of immunohistochemistry in situ hybridization and polymerase chain reaction for detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissues.
Masks and COVID-19 Prevention: Dr. Bill Morice
December 03, 2020 07:00 - 11 minutes - 10.5 MBhttps://newsnetwork.mayoclinic.org/discussion/mayo-clinic-research-confirms-critical-role-of-masks-in-preventing-covid-19-infection/
Hereditary Hearing Loss: Nicole Boczek, Ph.D.
December 01, 2020 07:00 - 11 minutes - 10.5 MB(00:48) Could you provide our listeners with a little bit about you and your background? (01:56) There's a fair amount of genetic hearing loss tests out there. Why did we decide to develop this one here at Mayo? (02:51) Can you tell me a little bit about the process that actually went into developing the test — the different research and that sort of thing? (04:03) What specific need do we meet with this particular test? (06:22) How were these results used in patie...
COVID-19 Vaccine Update: Dr. Bill Morice
November 26, 2020 07:00 - 15 minutes - 13.9 MBWilliam Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the latest on COVID-19 vaccines.
COVID-19 Antibody Testing Update: Elitza Theel, Ph.D.
November 24, 2020 07:00 - 16 minutes - 14.8 MB(01:07) Has the utility or the role of antibody testing changed or evolved in any way for you over the past months or since the pandemic began? (04:06) What do we know about the antibody response to the virus and how is our knowledge grown in that area? I think one question that people have is do we all make antibodies to the virus and how long do those antibodies last, and will they protect us from re-infection? (06:41) You mentioned briefly there's a neutralizing antibo...
Treatment for COVID-19: Dr. Bill Morice
November 19, 2020 07:00 - 14 minutes - 13.6 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., review the treatment options currently available for COVID-19.
Alpha-Gal Testing: Joshua Bornhorst, Ph.D., M.D.
November 17, 2020 06:01 - 8 minutes - 7.9 MBJoshua Bornhorst, Ph.D., M.D., explains how humans can develop an allergy to the alpha-gal molecule, and he describes a new allergen antibody test that can be used to detect it. Dr. Bornhorst also reviews other tests that should be used in conjunction with alpha-gal testing to accurately identify the scope and underlying cause of the allergy.
Alpha-Gal Testing: Joshua Bornhorst, Ph.D.
November 17, 2020 06:01 - 8 minutes - 7.9 MB(00:41) Dr. Bornhorst, could you provide our listeners with a little bit about you and your background? (01:15) Can you provide a brief overview of the alpha-gal galactose-alpha 1,3 galactose assay? (04:19) So I understand that most people obtain this allergy primarily from ticks and meat-derived products, and that it can cause symptoms such as hives, itching, difficulty breathing, and other unpleasant reactions. With that being said, can you tell us which patients should h...
COVID-19 and Herd Immunity: Dr. Bill Morice
November 12, 2020 07:00 - 13 minutes - 12.1 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss herd immunity and COVID-19.
Distinguishing COVID-19 From Other Respiratory Illnesses: Aaron Tande, M.D.
November 10, 2020 07:00 - 13 minutes - 12.4 MB(00:47) Can you tell us a little bit about yourself and how your role has changed since COVID-19? (02:02) How do you feel that testing will help Mayo and hospitals respond to this coming season's challenge? (03:38) Can you tell us a little bit about the algorithm and how it helps to address perhaps potential resource shortages, knowing that we probably can't test everyone for everything all the time, and that may not be the best approach anyway? (05:50) In your mind,...
COVID-19 Testing 101: Dr. Bill Morice
November 05, 2020 06:00 - 14 minutes - 13.6 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., review the testing options currently available to detect COVID-19.
B-Cell Lymphoblastic Leukemia Monitoring for Minimal Residual Disease: Min Shi, M.D., Ph.D.
November 03, 2020 06:00 - 12 minutes - 11.3 MB(00:45) Could you just provide our listeners with a little bit of information about you and your background? (01:00) The laboratory recently made some updates to this testing for minimal residual disease. Can you just give us a brief overview of that assay? (03:22) So these patients go through these treatments, and at what point do they really need this testing, or when should it be considered by clinicians to perform it? (05:18) What brought the laboratory to flow cy...
Enjoying Fall Activities Safely During COVID-19: Dr. Bill Morice
October 29, 2020 05:00 - 12 minutes - 11.9 MBResources: https://www.cdc.gov/coronavirus/2019-ncov/community/large-events/considerations-for-events-gatherings.html
Coagulopathies and COVID-19: Nahla Heikal, M.D.
October 27, 2020 05:00 - 15 minutes - 14.6 MBSpeaker 1: (00:39) Can you start by sharing a little bit about yourself and your expertise for our listeners? Speaker 1: (01:12) We're in this pandemic with COVID-19, and I'm hearing about people having hematologic responses to COVID-19. Can you tell us a little bit about what these responses are? Speaker 2: (04:53) Here at Mayo Clinic, do we have an assay or a testing profile that could assist physicians who are dealing with COVID-19 and their patients and help them loo...
Staying Safe Amid a Surge in COVID-19: Dr. Bill Morice
October 22, 2020 05:00 - 11 minutes - 10.9 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. With a surge in new cases happening now, and flu season coming soon, Dr. Morice and Bobbi Pritt, M.D., discuss the importance of continuing to follow safety precautions to help prevent COVID-19.
MDM2 Gene Amplification: William Sukov, M.D.
October 20, 2020 05:00 - 6 minutes - 5.86 MBSpeaker 1: (01:20) Today we want to talk about the MDM2 gene amplification assay. Can you give us a little bit of an overview of that test? Speaker 1: (02:16) Is there a certain subset of patients that should have this testing, and when should it be performed on those patients? Speaker 1: (02:50) So for those patients then, are there any other alternative test options that are available for them, or how else might these patients be diagnosed, and how does this specific tas...
Behind the Scenes in a Processing Lab During COVID-19: Jonathan Berry
October 15, 2020 05:00 - 11 minutes - 10.4 MBFull Show Notes: Speaker 1: (00:49) Can you share a little bit about yourself and how your role has changed since COVID-19 started? Speaker 1: (01:52) What kind of shortages have you seen in our laboratories? And maybe you could tell us a little bit about some innovative solutions your team's been working on to combat those shortages. Speaker 1: (04:41) Have you seen shortages in other areas of testing besides COVID testing? Speaker 1: (07:35) Are there any lessons y...
COVID-19 – At-Home Sample Collection vs. At-Home Testing: Dr. Bill Morice
October 08, 2020 05:00 - 13 minutes - 12.3 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., explain the difference between collecting a specimen sample at home to be used for COVID-19 testing versus performing a COVID-19 test at home. They also discuss factors that can affect test results and how to e...
COVID Testing at Home: Dr. Bill Morice
October 01, 2020 05:00 - 14 minutes - 13.3 MBResources: https://pubmed.ncbi.nlm.nih.gov/25502528/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538476/
Different Forms of Masking: Dr. Bill Morice
September 24, 2020 05:00 - 10 minutes - 9.76 MBWilliam Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice joins Dr. Bobbi Pritt to discuss the different forms of masking that are available and which type you should consider based on your state guidelines, in addition to the scientific studies performed.
Quality Management during COVID-19: Jill Hill
September 22, 2020 05:00 - 12 minutes - 11.8 MBTimestamps Dr. Bobbi Pritt: (00:45) Can you share a little bit about yourself and how your role has changed since COVID-19? Dr. Bobbi Pritt: (02:10) Has there been any additional quality management practices that have been put into place since the start of COVID-19? Dr. Bobbi Pritt: (04:13) Do you feel like these practices will continue to be followed going forward? Or do you think that some are just specific to the COVID-19 pandemic? Dr. Bobbi Pritt: (06:55) What ...
Screening and Surveillance Testing
September 17, 2020 05:00 - 10 minutes - 9.95 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how we can approach the upcoming flu season, and Bobbi Pritt, M.D., shares the differences between screening and surveillance approaches to testing for COVID-19.
Screening and Surveillance Testing: Dr. Bill Morice
September 17, 2020 05:00 - 10 minutes - 9.95 MBWilliam Morice, II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how we can approach the upcoming flu season, and Bobbi Pritt, M.D., shares the differences between screening and surveillance approaches to testing for COVID-19.
Labor Day Weekend Precautions: Dr. Bill Morice
September 03, 2020 05:01 - 11 minutes - 10.2 MBWilliam Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how we can prepare for the upcoming influenza season and take necessary precautions as we approach Labor Day weekend.
Laboratory Perspective of COVID-19: Aimee Boerger and Emily Fernholz
August 25, 2020 05:00 - 14 minutes - 13.3 MBResources: https://news.mayocliniclabs.com/covid19/
Leadership in a Time of Uncertainty: Dr. Bill Morice
August 20, 2020 05:00 - 16 minutes - 15.6 MBWilliam Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how leadership practices have shifted since the onset of COVID-19, the creation of our command center, and how the team has made significant changes to ensure there is an increase in open communication with staff.
Maximizing Testing Capacity: Dr. Bill Morice
August 13, 2020 05:00 - 10 minutes - 9.79 MBResources: COVID-19 Resource Center
Herd Immunity: Dr. Bill Morice
July 30, 2020 05:00 - 10 minutes - 10 MBTimestamps: Speaker 1: (01:03) Do you want to tell us a little bit for the listeners, what herd immunity is? Speaker 1: (02:49) With your immunology background, if you have any thoughts on what would be the ideal way in your mind? Speaker 1: (06:21) So it does show the power of the immune response, but it is that question of, is it going to be antibodies? Is it going to be T cells? Is it going to be a mixture of both and can a vaccine elicit a protective response from those d...
600th Case of the Week on Creepy Dreadful Wonderful Parasites: Dr. Bobbi Pritt
July 28, 2020 13:00 - 13 minutes - 12.2 MBTimestamps: Speaker 2: (01:12) Where does it all start? Speaker 2: (04:32) How many followers have you? Speaker 2: (05:59) So what would your advice be to someone who might listen to this and want to follow in your footsteps? Speaker 2: (10:41) So you've been doing this now for a long time, 600 cases on your blog, do you have a few favorites? Resources: Creepy Dreadful Wonderful Parasite Blog Twitter: @parasitegal Facebook: https://www.facebook.com/ParasiteGal/
Pooling and Precautions: Dr. Bill Morice
July 23, 2020 05:00 - 14 minutes - 13.2 MB01:21 Could you give us the updates on what you see the state of testing to be today? 01:53 What are some of the new things on the horizon? You know, we're hearing about pooling and antigen testing. 08:34 What are your thoughts on that?
Benefits of Wearing a Mask: Dr. Bill Morice
July 16, 2020 05:00 - 10 minutes - 9.85 MBTimestamps: Speaker 1: (01:14) Can you tell our listeners about the state of testing today? Speaker 1: (05:14) You've been posting on Twitter, some really interesting statistics, do you want to share some of those? Speaker 1: (09:46) Do you have designer masks, Bill, and do you match your outfit for the day? Resources: https://news.mayocliniclabs.com/covid19/
Supply Chain Management during COVID-19: Dr. Paul Jannetto
July 14, 2020 05:00 - 11 minutes - 10.5 MB00:44 So can you tell me a little bit about what your normal role was at Mayo Clinic before COVID happened? Then how has that changed as the COVID pandemic started and progressed? 02:06 So, what are some of the current challenges facing the supply chain and what have been some of Mayo Clinic’s strategies to successfully navigate through these evolving supply chain shortages and demands for supplies during the COVID-19 pandemic? 05:51 What are some of the innovative ways that ...
Delta Air Lines Partnership: Dr. Bill Morice
July 09, 2020 05:00 - 14 minutes - 13.3 MB(01:01) Can you tell us how lab testing capacity is in general at Mayo Clinic and across the United States? (03:34) We’re trying to balance how we test for the routine stuff, in addition to meeting COVID demands? (04:40) How should we be using testing to manage this COVID-19 outbreak? (06:36) So the partnership you mentioned, do you want to tell us a little bit more about that? Because it was recently announced and not everyone may have seen those announcements with what w...
Neutralizing Antibody Assay, Explained: Dr. John Mills
June 30, 2020 05:00 - 14 minutes - 13.8 MBTimestamps: Speaker 1: (01:00) Perhaps you could start off by just telling us how is this test different than the other antibody tests? What is a neutralizing antibody to begin with? Speaker 1: (02:40) Can you tell us about the new neutralizing antibody test then and how it came about? Speaker 1: (03:39) What did you do specifically to make it a clinical test? Speaker 1: (04:50) How many tests then can be completed each day? Speaker 1: (05:11) How would you incorporate ...
Future of COVID-19 Laboratory Testing: Dr. Bill Morice
June 25, 2020 05:00 - 13 minutes - 12.3 MB01:16 What are you thinking when you look to the future for laboratory testing for COVID-19? 03:05 What are your thoughts on that? What would be some ways that we could predict who would be at risk for severe disease and really might go downhill quickly? 04:47 So should we be testing for T-cells? Are there any T-cell marker tests in the future? 05:41 Can you tell us a little bit about that from your view as our chair? Resources: https://news.mayocliniclabs.com/covid19/
New COVID-19 Test Launch and Employee Testing: Dr. Bill Morice
June 18, 2020 05:00 - 13 minutes - 12.5 MBTimestamps: Speaker 1: (00:39) So let's start by talking about the new neutralizing antibody test. Can you tell us a little bit about this test and how it came about? Speaker 1: (04:55) So we are screening all of the employees throughout the Mayo Clinic enterprise. Can you tell us about this and the scope and the purpose behind this program? Speaker 1: (07:26) So a lot of things to consider, I'm sure our listeners are now saying, so how did you roll it out? Or what are the p...
Innovation in COVID-19 Testing: Dr. Bill Morice
June 11, 2020 18:00 - 11 minutes - 10.4 MBFull Show Notes (Timestamps) Speaker 1: (00:50) So this is now our six months in a world with COVID-19, which is just amazing. What is new in terms of testing at Mayo Clinic Laboratories for COVID-19? Speaker 1: (02:23) It has the potential to really help a lot of patients, if you can show that giving convalescent plasma is going to be helpful to our patients struggling with COVID-19. Speaker 1: (04:04) So as chair for our department, what are some of your considerations now...
Using COVID-19 Testing to Help Restart the Economy: Dr. Bill Morice
June 04, 2020 05:00 - 13 minutes - 12.3 MB01:23 How do you envision that we could use these two types of tests to help restart our economy? 07:04 When you test one day, what does that mean? 08:59 What can the laboratory do to help guide how our tests are used for clinical decision making public policy and even help guide how future tests are created so that they can best serve our patients? Resources: https://news.mayocliniclabs.com/covid19/ https://news.mayocliniclabs.com/2020/05/18/client-virtual-town-hall/