Answers from the Lab
309 episodes - English - Latest episode: 1 day ago -A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.
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Episodes
Infectious Diseases on the Move: Bill Morice, M.D., Ph.D.
June 06, 2024 06:00 - 15 minutes - 20.9 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss why measles remains a virus of concern, how avian flu continues to spread, and new developments in the federal regulation of laboratory-developed tests. Their discussion includes: How a person infected with measles recently traveled through a U.S. ai...
Tests Aid Diagnosis of Cancer-Associated Neurological Disorders: Divyanshu Dubey, M.B.B.S.
June 04, 2024 06:00 - 14 minutes - 19.9 MBDivyanshu Dubey, M.B.B.S., explains how Mayo Clinic Laboratories' unique PDE10A and TRIM46 assays facilitate care for central nervous system disorders triggered by cancer. Early diagnosis and treatment are important for managing disabling neurological symptoms and malignancy. (00:32) Could you tell us a bit about your background and your role at Mayo Clinic? (01:26) How do the tests that are coming live relate to the larger disease state of neurological disorders? (02:44)...
Get to Know DLMP’s Vice Chair of Research: Peter Lucas, M.D., Ph.D.
May 30, 2024 06:00 - 24 minutes - 34.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Peter Lucas, M.D., Ph.D., vice chair of Research for the Department of Laboratory Medicine and Pathology (DLMP) at Mayo Clinic. Their discussion includes: Dr. Lucas’ extensive pathology and research background and his journey to Mayo Clinic. His goals for expanding DLMP’s research activities and advancing innovation in diagnostics. How...
Avian Flu Outbreaks and New COVID-19 Variants: Matthew Binnicker, Ph.D.
May 23, 2024 06:00 - 10 minutes - 14.8 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., professor of laboratory medicine and pathology and clinical virologist at Mayo Clinic. They discuss the widespread outbreaks of H5N1 bird flu and the new “FLiRT” variants of COVID-19. Specific topics of discussion include: The current situation of avian flu activity across the world and throughout the United States...
Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S.
May 21, 2024 06:00 - 14 minutes - 19.7 MBRobert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S., explain how Mayo Clinic Laboratories' augmented MayoComplete Solid Tumor Panel better profiles tumor genetics. Defining tumor pathogenesis can guide targeted cancer therapy. (00:31) Can you tell us a little about yourself and your background — Beth? (01:24) Stephanie, what about you? (01:42) Dr. Jenkins, a little bit about yourself and your background, please? (02:25) Could you provide a...
New Panels Help Find Cause of Rapidly Progressive Dementia: Gregory (Gregg) Day, M.D.
May 14, 2024 06:00 - 24 minutes - 33.4 MBRapidly progressive dementia covers many conditions, including Creutzfeldt-Jacob disease (CJD). Gregory (Gregg) Day, M.D., explains how Mayo Clinic Laboratories' new evaluations help identify the cause of rapidly progressive dementia, to guide prognosis and treatment decisions. Show notes Speaker 3: (00:32) Can you provide a little background about your role here at Mayo Clinic and experience with this disease state? Speaker 3: (01:21) Can you give us an understanding of rap...
Get to Know the DLMP Chair: Eric Hsi, M.D.
May 09, 2024 06:00 - 12 minutes - 16.9 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic. Their discussion includes: Dr. Hsi’s experience in the field of pathology and what he is looking forward to working on as the new chair of the Department of Laboratory Medicine and Pathology (DLMP) at Mayo Clinic. Some common challenges facing lab...
Oral fluid offers an alternative specimen for controlled substance monitoring: Paul Jannetto, Ph.D.
May 07, 2024 06:00 - 7 minutes - 10.5 MBPaul Jannetto, Ph.D., explains the advantages that Mayo Clinic Laboratories' oral fluid drug screening offers over typical urine tests. Oral samples are easier to collect and harder to adulterate. (00:32) Can you tell us a little bit about yourself and your background? (01:46) Can you please provide an overview of laboratory testing for substance use disorders and specifically Mayo Clinic's new oral fluid controlled substance monitoring option? (03:47) Which patients sho...
FDA Issues Final Rule to Regulate LDTs: Bill Morice, M.D., Ph.D.
May 02, 2024 17:01 - 18 minutes - 25 MBIn this special episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the final rule issued by the U.S. Food and Drug Administration (FDA) on April 29, 2024, to make explicit its plan to regulate laboratory-developed tests (LDT) as medical devices under the Federal Food, Drug, and Cosmetic Act. Their discussion ...
The Growing Crisis of Antimicrobial Resistance: Robin Patel, M.D.
May 02, 2024 06:00 - 8 minutes - 11.4 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Robin Patel, M.D.,director of the Infectious Diseases Research Laboratory and co-director of the Bacteriology Laboratory at Mayo Clinic. They discuss antimicrobial resistance and why it’s a major global health concern. Specific topics of discussion include: Background information on antimicrobial resistance and why it is a growing threat to...
Assay provides quick diagnosis of VEXAS syndrome: David S. Viswanatha, M.D.
April 30, 2024 06:00 - 14 minutes - 20.4 MBDavid S. Viswanatha, M.D., explains how Mayo Clinic Laboratories' new assay provides rapid, definitive diagnosis of VEXAS, a recently identified syndrome affecting older men. Early diagnosis is key to managing the condition, which severely impacts multiple organs and blood. (00:31) Could you please provide a little bit about yourself and your background? (01:30) Would you please share a brief overview of the UBA1Q assay? (02:13) Would you provide an overview of VEXAS syn...
Alzheimer’s Disease and Testing Innovations: Bill Morice, M.D., Ph.D.
April 25, 2024 06:00 - 11 minutes - 15.5 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss testing innovations for Alzheimer’s disease and cognitive impairments, and how laboratorians can responsibly help shape the future of healthcare. Their discussion includes: The latest news about the U.S. Food and Drug Administration’s (FDA) proposed ...
Assay identifies patients eligible for new ovarian cancer drug: Maryam Shahi, M.D
April 23, 2024 06:00 - 5 minutes - 8.08 MBMaryam Shahi, M.D., explains how Mayo Clinic Laboratories' unique biomarker test (TEST ID: AFOLR) determines which patients would likely benefit from a new treatment for recurrent epithelial ovarian cancer. Disease recurrence is common, and about one-third of patients respond to the new medication. (00:32) Could you provide us with a little bit of information about yourself and your background? (01:18) Can you start with a brief overview of the assay? (02:13) Which pat...
Lab Week and Noteworthy News: Bill Morice, M.D., Ph.D.
April 18, 2024 06:00 - 11 minutes - 15.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss current events including Medical Laboratory Professionals Week, recent healthcare conferences, advocacy efforts, measles, and bird flu. Their discussion includes: Key takeaways from the Becker’s Healthcare Annual Meeting and the College of American P...
Assay monitors response to monoclonal antibody therapy: Maria Alice Willrich, Ph.D.
April 16, 2024 06:00 - 9 minutes - 12.5 MBMaria Alice Willrich, Ph.D., explains how Mayo Clinic Laboratories' new assay provides therapeutic drug monitoring of risankizumab, or RISA. Test results help guide care for patients with plaque psoriasis, psoriatic arthritis, and Crohn's disease. (00:32) Do you mind giving the audience more information about yourself and your background? (01:53) Could you please give a brief overview of this assay? (03:35) Which patients should have this testing and when should it be pe...
Tick Season Outlook: Elitza Theel, Ph.D.
April 11, 2024 06:00 - 17 minutes - 24.7 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to discuss tick-borne diseases and the latest testing options. Specific topics of discussion include: The types of tick-borne diseases found throughout the United States. Algorithmic approaches and testing methods used to diagnose tick-borne disea...
Noninvasive plasma biomarker testing provides faster answers: Alicia Algeciras-Schimnich, Ph.D.
April 09, 2024 06:00 - 17 minutes - 24.7 MBAlicia Algeciras-Schimnich, Ph.D., discusses how Mayo Clinic Laboratories’ new noninvasive blood test for Alzheimer’s disease identifies the p-tau217 biomarker, which is associated with the accumulation of amyloid beta in the brain. Positive test results can facilitate access to disease-modifying therapies. (00:32): Dr. Algeciras, could you just provide a little bit of background on your role at Mayo Clinic? (01:45): So before we get into the test itself, can you just explain a...
Dengue Outbreaks and Advancements in Colon Cancer Screening: Bill Morice, M.D., Ph.D.
April 04, 2024 18:00 - 11 minutes - 15.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss current events including dengue outbreaks, new colon cancer screening technology, and insurance coverage of innovative lab tests. Their discussion includes: The surge of dengue cases in Latin America, and best practices for tick and mosquito bite pre...
Assay identifies rare tick-borne bacteria: Bobbi Pritt, M.D.
April 02, 2024 06:00 - 8 minutes - 11.6 MBBobbi Pritt, M.D., explains how Mayo Clinic Laboratories' new assay identifies less-common tick-borne bacteria in whole blood. The assay is recommended when tick-borne bacterial infection is suspected but standard testing is unrevealing. (00:33) Do you mind giving us a brief introduction of yourself and what you do at Mayo? (01:45) Can you tell us a little about the test and how it came to be? (03:00) Could you explain the types of patients this test would be best suited...
Why Measles Is on the Rise: Matthew Binnicker, Ph.D.
March 28, 2024 06:00 - 15 minutes - 21.9 MBThe Centers for Disease Control and Prevention (CDC) issued a recent health advisory in response to the increasing number of measles outbreaks in the United States. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., professor of laboratory medicine and pathology and clinical virologist at Mayo Clinic, to discuss why measles is in the news again and how we can preven...
Targeted panel boosts accuracy of hereditary pancreatitis testing: Experts: Linda Hasadsri, M.D., Ph.D., and Huong T. Cabral, M.S., C.G.C.
March 26, 2024 06:00 - 10 minutes - 14.4 MBLinda Hasadsri, M.D., Ph.D., and Huong T. Cabral, M.S., C.G.C., explain how Mayo Clinic Laboratories' targeted test panel facilitates accurate diagnosis of hereditary pancreatitis, which heightens the risk for pancreatic cancer. Test results can guide cancer monitoring for patients and their families. (00:33) Dr. Hasadsri, can you tell the audience a little bit about yourself and your background? (01:32) And Ms. Cabral? (02:03) Can you please give the audience a brief ov...
Industry Updates From the Nation’s Capital: Bill Morice, M.D., Ph.D.
March 21, 2024 06:00 - 13 minutes - 18 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss important industry updates and legislative insights gathered from Dr. Morice’s recent trip to Washington, D.C. Their discussion includes: The status of current laboratory-related legislative efforts, including the Protecting Access to Medicare Act (P...
Test identifies Lynch syndrome for targeted cancer monitoring: Wei Shen, Ph.D., and Rhianna Urban, M.S., CGC
March 19, 2024 06:00 - 18 minutes - 25.6 MBWei Shen, Ph.D., and Rhianna Urban, M.S., CGC, explain how Mayo Clinic Laboratories' gene panel establishes a diagnosis of Lynch syndrome, which heightens the risk for several cancers. Test results can guide cancer surveillance for patients and their families. (00:32) Would each of you share a little bit about yourselves and your background? Dr. Shen? (01:25) Rihanna, could we have you give a little background about yourself as well? (01:48) Could you provide us with an ...
Syphilis Testing Updates: Elitza Theel, Ph.D.
March 14, 2024 06:00 - 19 minutes - 26.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to follow up on the syphilis epidemic and discuss updated testing recommendations. Specific topics of discussion include: Background information on syphilis and the epidemic occurring in the United States. The report recently published by the Cente...
Testing aids nicotine-use cessation: Paul Jannetto, Ph.D.
March 12, 2024 06:00 - 9 minutes - 13.5 MBPaul Jannetto, Ph.D., explains how Mayo Clinic Laboratories' nicotine testing benefits patients in substance-use cessation programs and other settings. The serum and urine tests quantify nicotine and various metabolites. (00:32) Can you tell us a little bit about yourself and your background? (01:42) Can you please provide an overview of substance use disorders, specifically nicotine dependence, and Mayo Clinic's nicotine testing options? (04:33) Which patients should ha...
Final Rule on LDTs May Be Coming Soon: Bill Morice, M.D., Ph.D.
March 07, 2024 07:00 - 10 minutes - 14.7 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the Food and Drug Administration’s (FDA) progress on making a final rule around regulating laboratory-developed tests (LDTs). Their discussion includes: How the FDA’s proposed rule on regulating LDTs has advanced to the White House Office of Managem...
Black History Month: Bill Morice, M.D., Ph.D.
February 29, 2024 07:00 - 8 minutes - 11.8 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to honor Black History Month. They reflect on important advancements in healthcare and laboratory medicine that were led by Black healthcare professionals and scholars. They also discuss health inequities that impact communities throughout the United States. Thei...
Adrenal Gland Tumors: Stefan Grebe, M.D., Ph.D., and Irina Bancos, M.D.
February 22, 2024 07:00 - 13 minutes - 18.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Stefan Grebe, M.D., Ph.D., co-director of the Clinical Mass Spectrometry and Test Development Laboratory in the Department of Laboratory Medicine and Pathology, and Irina Bancos, M.D.,consultant in the Division of Endocrinology, Diabetes, and Metabolism with a joint appointment in biochemistry and immunology. They discuss the diagnosis and ma...
Test panel guides diagnosis of early onset IBD: Ann Moyer, M.D., Ph.D.
February 20, 2024 07:00 - 12 minutes - 17.3 MBAnn Moyer, M.D., Ph.D., explains how Mayo Clinic Laboratories' test panel provides comprehensive evaluation of patients with suspected monogenic early onset inflammatory bowel disease, or IBD. Accurate diagnosis is key to guiding therapy for patients, who might be as young as age 2. (00:32) Could you please tell us a little bit about your background? (01:17) Could you please do a brief overview of our EOIBD test? (03:24) Which patients should have this testing and when s...
Emerging and Reemerging Diseases: Bill Morice, M.D., Ph.D.
February 15, 2024 07:00 - 11 minutes - 15.5 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss current activity of infectious diseases. Their discussion includes: Vector-borne diseases that are causing public health concerns, and the multi-agency public health strategy recently released by the U.S. Department of Health and Human Services to addr...
Tests aid diagnosis of primary biliary cholangitis: Anne Tebo, Ph.D.
February 13, 2024 07:00 - 16 minutes - 22.8 MBAnne Tebo, Ph.D., explains how Mayo Clinic Laboratories' new serum tests help overcome the challenges of diagnosing primary biliary cholangitis, or PBC. Test results can guide clinical care for patients with this life-threatening autoimmune liver disease. (00:32) Could you please provide a little information about your background? (02:09) Please give a brief overview of the new test panels. (05:35) Which patients should have this testing and when should it be performed? ...
Assay enhances and simplifies M-proteins screening: David Murray, M.D., Ph.D.
February 06, 2024 07:00 - 17 minutes - 24.7 MBDavid Murray, M.D., Ph.D., explains how Mayo Clinic Laboratories' MASS-FIX Quantitation assay provides next-generation screening for M-proteins, which are associated with multiple myeloma and other diseases. The assay better quantitates the blood proteins, for improved patient care and simpler test ordering. (00:32) Could you provide us with a little bit about yourself and your background? (02:56) Would you elaborate on the role of you and the Mayo Clinic team in advancing insi...
The Pulse on Global Diagnostics: Bill Morice, M.D., Ph.D.
February 01, 2024 07:00 - 11 minutes - 15.4 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss what companies in the healthcare and diagnostics industries are focusing on in 2024. Their discussion includes: Insights from the J.P. Morgan Healthcare Conference, and where investments are happening in the diagnostics industry. Observations from vis...
Assay stratifies pregnant women's preeclampsia risk: Joshua Bornhorst, Ph.D.
January 30, 2024 07:00 - 5 minutes - 7.16 MBJoshua Bornhorst, Ph.D., explains how Mayo Clinic Laboratories' unique blood test identifies pregnant women at risk of developing preeclampsia with severe features. Test results can guide clinical management, to safeguard maternal and neonatal health. Speaker 3: (00:32) Can you share a little about yourself and your background? Speaker 3: (01:00) Can you provide us with an overview of this new preeclampsia assay? Speaker 3: (02:33) Can you share what will be reported with t...
Evolution of Syphilis: Elitza Theel, Ph.D.
January 18, 2024 07:00 - 13 minutes - 18 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to talk about the sexually-transmitted disease syphilis. Specific topics of discussion include: The history, cause, and symptoms of syphilis. A rare recent outbreak of ocular syphilis cases. The dramatic rise in syphilis and congenital syphilis c...
A New Year with Familiar Viruses: Bill Morice, M.D., Ph.D.
January 11, 2024 07:00 - 11 minutes - 16.1 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to welcome the new year and discuss the increase of respiratory viruses. Their discussion includes: The increasing number of COVID-19 and influenza cases across the United States. The endemic state of COVID-19 and tools for prevention. The continued need to pro...
Lipid assay improves cardiovascular risk prediction: Jeff Meeusen, Ph.D.
January 04, 2024 07:00 - 8 minutes - 12 MBJeff Meeusen, Ph.D., explains how Mayo Clinic Laboratories' new MI-Heart Ceramides assay helps guide the management of patients with mildly to moderately high cholesterol. The test measures levels of lipids beyond cholesterol that boost cardiovascular risk. Show notes (00:31) Could you provide us a little bit about your background? (01:20) Could you give us a brief overview of this assay? (02:45) What patients should have this test and when should it be performed? (04:2...
Test helps identify elusive central nervous system pathogens: Robin Patel, M.D.
January 02, 2024 07:00 - 7 minutes - 9.86 MBRobin Patel, M.D., explains how a new Mayo Clinic Laboratories' assay can identify central nervous system pathogens that standard tests fail to detect. Rapid, precise diagnosis is essential to preventing long-term effects from these infections. Show notes Speaker 3: (00:32) Please give us a brief introduction of yourself and your role at Mayo Clinic. Speaker 3: (01:44) Could you please expand a bit on this newly developed sequencing assay — which is a shotgun metagenomic tes...
Unique testing helps identify cause of sudden cardiac death: Linnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC
December 28, 2023 07:00 - 13 minutes - 18.4 MBLinnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC, describe how Mayo Clinic Laboratories' postmortem genetic tests can provide answers after a sudden unexplained cardiac death. Test results are important for managing family members' risk for cardiovascular disease. Show notes (00:32) Would each of you share a little bit about yourselves and your backgrounds? (01:13) Could you provide us with an overview of these new tests? (02:31) Can you expand on why these postmortem ...
Assay finds genetic cause of low bile flow: Devin Oglesbee, Ph.D.
December 26, 2023 07:00 - 10 minutes - 14.1 MBDevin Oglesbee, Ph.D., explains how Mayo Clinic Laboratories' cholestasis gene panel identifies mutations that cause low flow of bile from the liver. Test results help guide treatment decisions that can prevent liver damage. Show notes (00:32) Could you please provide us a little information about your background? (01:46) Could you please give the audience a brief overview of this assay? (03:45) Which patients should have this testing and when should it be performed? ...
The Past, Present, and Future of Diagnostics: Bill Morice, M.D., Ph.D.
December 21, 2023 07:00 - 13 minutes - 18.3 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to reflect on key moments from 2023 and to discuss what may lie ahead in 2024. Their discussion includes: A look back at impactful events from 2023 in laboratory medicine and diagnostics. What’s top of mind today heading into the holidays. Specula...
Assay identifies biomarker of autoimmune encephalitis subtype: Andrew McKeon, M.B., B.Ch., M.D.
December 19, 2023 07:00 - 17 minutes - 24.4 MBAntibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers From the Lab" podcast, Andrew McKeon, M.B., B.Ch., M.D., explains how Mayo Clinic Laboratories' GABA-A receptor antibody assay aids diagnosis of this serious but treatable condition. Show notes (00:32) Could you provide a little information on your role here at Mayo Clinic? (01:1...
Milestone Treatments for Sickle Cell Disease: Bill Morice, M.D., Ph.D.
December 14, 2023 07:00 - 15 minutes - 22 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) recent approval of two gene therapies for sickle cell disease. Their discussion includes: The cause and characteristics of sickle cell disease. How the new cell-based gene therapies, Casgevy ...
Panel offers proactive drug monitoring for IBD: Maria Willrich, Ph.D., and Melissa Snyder, Ph.D.
December 12, 2023 07:00 - 16 minutes - 22.5 MBMaria Willrich, Ph.D., and Melissa Snyder, Ph.D., describe Mayo Clinic Laboratories' panel for proactive therapeutic drug monitoring of patients with inflammatory bowel disease. The panel expands options for clinicians assessing patients' response to the drugs infliximab and adalimumab. (00:32) Could you provide a little bit of background information about yourselves? (02:18) Would you give the audience a brief overview of the assay? (04:18) Which patients should have th...
Comments on the FDA’s Proposed Rule: Bill Morice, M.D., Ph.D.
December 07, 2023 07:00 - 13 minutes - 18.4 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the U.S. Food and Drug Administration’s (FDA) proposed rule on laboratory-developed tests (LDTs) and the comments Mayo Clinic submitted to the FDA. Their discussion includes: How Mayo Clinic responded in its comments to the FDA on the pro...
Protecting Against Winter Respiratory Viruses: Bill Morice, M.D., Ph.D.
November 30, 2023 07:00 - 11 minutes - 15.5 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss current respiratory virus activity and the importance of staying up-to-date on preventive vaccines. Their discussion includes: The current outlook on COVID-19 cases and the importance of remaining vigilant with prevention efforts. The r...
Congressional and Federal Updates: Bill Morice, M.D., Ph.D.
November 23, 2023 07:00 - 15 minutes - 21.7 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the one-year delay to clinical laboratory payment cuts recently passed by Congress and the importance of responding to the FDA’s proposed rule on laboratory-developed tests. Specific discussion points include: How Congress passed the sh...
Perspectives from Washington, D.C.: Bill Morice, M.D., Ph.D.
November 16, 2023 07:00 - 14 minutes - 19.6 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss key takeaways from Dr. Morice’s recent visit in Washington, D.C. Their discussion includes: How device manufacturers are evolving and collaborating within the changing landscape. The importance of submitting comments in response to th...
RNA test identifies large B-cell lymphoma subtypes: Lisa Rimsza, M.D.
November 14, 2023 07:00 - 10 minutes - 15 MBLisa Rimsza, M.D., explains how Mayo Clinic Laboratories' unique PM3CX test can accurately define subtypes of large B-cell lymphoma. Precise diagnosis is critical to choosing appropriate chemotherapy for these cancers. Speaker 2: (00:32) Could you provide a brief background about yourself? Speaker 2: (01:12) Would you give us an overview of the PM3CX test? Speaker 2: (03:02) Which patients should have this testing? Speaker 2: (05:14) Is this test qualitative and RN...
Safeguards for AI in Healthcare: Bill Morice, M.D., Ph.D.
November 09, 2023 07:00 - 10 minutes - 14.7 MBIn this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss strategies for responsible innovation and how new standards for artificial intelligence (AI) safety will impact laboratory medicine and diagnostics. Their discussion includes: Highlights of the Executive Order issued by President Biden ...