Answers from the Lab

The State of COVID-19 Now: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update with Bobbi Pritt, M.D. This week, Dr. Morice and Dr. Pritt step back and look at where the COVID-19 pandemic stands now, and they consider the potential effects that the omicron variant, expanded testing availability, and the upcoming holidays all could have.

Omicron Variant: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update with Bobbi Pritt, M.D. As the omicron variant of SARS-CoV-2 gains attention and generates concern, Dr. Morice and Dr. Pritt discuss what’s being done to learn more about this new variant and the effects it could have on the fight against COVID-19.

CYPZ: Michelle Kluge, M.S., CGC

(00:32): Can you tell us a little about yourself and your background? What is the role of a genetic counselor in the Genomics Laboratory? (01:59): The Genomics Laboratory performs a lot of different genetic tests. What is your area of focus? (03:00): Give a brief overview of congenital adrenal hyperplasia. (05:44): Which patients should have this testing, and when should it be performed? (06:35): Can you tell us a bit about what sets MCL’s CYP21A2 offering apart from other ...

Lab-Developed Tests: Shannon Bennett

This week on "Answers From the Lab," Shannon Bennett, director of Regulatory Affairs for Mayo Clinic’s Department of Laboratory Medicine and Pathology, joins William Morice II, M.D., Ph.D., and Bobbi Pritt, M.D., to discuss tests that are developed by individual laboratories, rather than commercial manufacturers, and how upcoming regulation may affect those tests.

Hereditary Oncology Testing: Wei Shen, Ph.D.

(00:32): But before we get started, Dr. Shen, could you provide us with a little bit about you and your background? (01:15): So why don't we start our discussion today with having you give us a brief overview of these new hereditary oncology panels. (03:56): Can you tell us which patients should have this type of testing and when it should be performed? (05:31): Do you want to talk about what other test options are available and how our testing is different or how it compares to...

COVID-19 Antibody Testing: Dr. Elitza Theel

This week on the podcast, Elitza Theel, Ph.D., director of Mayo Clinic’s Infectious Diseases Serology Laboratory, joins "Answers From the Lab" with Bobbi Pritt, M.D. In this episode, Dr. Pritt and Dr. Theel discuss antibody testing for COVID-19, including why this testing is done and when it’s most useful.

IDENT: Audrey Schuetz, M.D.

(00:32): Today, we will be discussing staphylococcal testing at Mayo Clinic Laboratories. Before we start, Dr. Schuetz, could you please provide our listeners with a little bit about you and your background?  (01:02): As we get started on this initiative, can you provide a brief overview of this testing and its intended use?  (02:36): Could you describe for us which patients should have this testing and when it should be performed — including how this new testing improves upon ...

COVID-19, Moving Forward: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update with Bobbi Pritt, M.D. In this episode, Dr. Morice and Dr. Pritt discuss the state of COVID-19 now, along with factors that could influence how the pandemic plays out from here.

The State of COVID-19 Today: Dr. Bill Morice

The Global Impact of COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update with Bobbi Pritt, M.D. In this episode, Dr. Morice talks about his participation in President Biden’s Global COVID-19 Summit and discusses the toll the pandemic has taken on countries around the world.

NF155: John Mills, Ph.D.

(00:32): Before we get into the test itself, Dr. Mills, I'd love for you to tell our audience just a little bit about yourself, your background, your role here at Mayo clinic.   (01:41): Can you just give our audience a brief overview of the assay?   (05:20): I really appreciate how the lab has looked at other approaches and decided that this is the best one. Is that an accurate kind of summary.   (06:16): They'll get the result that they need with just one test, right?  ...

How AI is Shaping the Future of Laboratory Medicine: Dr. Bill Morice

This week on "Answers From the Lab,” William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, is joined for his weekly leadership update by Jason Hipp, M.D., Ph.D., chair of Mayo Clinic’s new Division of Computational Pathology and AI, to discuss how artificial intelligence and other forms of clinical informatics have the potential to transform laboratory medicine and pathology.

Mitochondrial disease: Linda Hasadsri, M.D., Ph.D.

(00:32): Before we get started, Dr. Hasadsri, could you provide us with a little bit about you and your background? (02:43): Can you differentiate a little bit between what we offer from a molecular standpoint, but what we offer from a biochemical genetic standpoint in terms of mitochondrial testing? (06:25): When you would utilize this mitochondrial testing and what kind of patient treatment is this kind of testing guide? How is this utilized in terms of the way the patient is t...

The Value of a Flu Vaccine Amid COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., talk about the potential for a fall uptick in respiratory viruses, such as the flu and RSV, and explain the protection that an influenza vaccine can offer.

T-cell Lymphoma Testing: Dr. Andrew Feldman

(00:32)  Thanks for that introduction, Dr. Pritt. Today, we're actually going to be discussing T-cell lymphomas with Dr. Andrew Feldman. But before we really get started talking about this disease state, Dr. Feldman, could you provide us with a little bit of background about you and your role here at Mayo Clinic? (01:10)  So at your work at Mayo clinic, you’re involved in the clinical side and that you're reading all of these patient cases as a meta-pathologist, but you also have a...

COVID-19 National Strategy: Dr. Bill Morice

Additional Resources https://covid.cdc.gov/covid-data-tracker/#county-view https://www.whitehouse.gov/covidplan/

PGXQP: Ann Moyer, M.D., Ph.D.

(00:31) Dr. Moyer, could you provide us a little bit about you and your background? (01:18)  Would you mind sharing just a brief overview of the focus pharmacogenomics panel?   (03:32)  So coming back to that patient focus, which patients should have this testing? And when do you recommend to be performed?   (05:17)  Can you talk a little bit about what alternative test options are available and how they compare?    (07:58)  Can you comment on how the results from this test ar...

COVID-19 Vaccine Myths: Dr. Bill Morice & Dr. Matt Binnicker

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, is on the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., are joined by Matthew Binnicker, Ph.D. The three delve into common myths about the COVID-19 vaccines, and emphasize that the vaccines are effective and safe.

COVID-19 Vaccine Boosters: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., explain COVID-19 vaccine boosters: what they are, how they work, and why they may be helpful in fighting the global pandemic.

Candida Auris: Dr. Nancy Wengenack

Nancy Wengenack, Ph.D., director of the Mycology and Microbacteriology Laboratories in Mayo Clinic’s Department of Laboratory Medicine and Pathology, joins the "Answers From the Lab" podcast this week. In this episode, Dr. Wengenack and Bobbi Pritt, M.D., discuss the fungal infection Candida auris.

COVID-19 Breakthrough Infections: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., talk about cases of COVID-19 being seen in people who are fully vaccinated and explain why that doesn’t mean the vaccines aren’t working.

COVID-19 Update: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., review where the COVID-19 pandemic stands today and how it may change as we head into the fall.

MAG Antibody Testing: John Mills, Ph.D.

(00:33)  Could you please tell the audience a little bit about yourself and your background before we get to?   (01:07)  So just as an overview, this new MAG test, can you kind of give us a general idea of the assay, the methodology, and how this could be used clinically?   (01:59)  Can you maybe expound upon the role of the M protein, how it relates to the MAG antibody and also that unique testing methodology that we use?   (03:15)  Can you describe how those will present to ...

COVID-19 Surge: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., talk about what the recent surge in COVID-19 cases means and how we can all do our part to help prevent further spread.

Coronavirus Delta Variant: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the rise in cases of COVID-19 caused by the coronavirus delta variant in the U.S., especially in areas with low vaccination rates.

Vector-Borne Diseases: Dr. Bobbi Pritt & Dr. Bill Morice

This episode of “Answers from the Lab” features Bobbi Pritt, M.D., chair of Mayo Clinic’s Division of Clinical Microbiology, and William Morice II, M.D., Ph.D., chair of Mayo’s Department of Laboratory Medicine and Pathology and president of Mayo Clinic Laboratories, discussing how to prevent, diagnose, and treat vector-borne diseases — illness you get from blood-feeding anthropods like ticks and mosquitos — that are more common during the summertime.

Disaccharidase Activity Panel: Puanani (Pua) E. Hopson, D.O.

(00:32): Before we get started, Dr. Hopson, could you please share a little about you and your background with our listeners?   (01:16): Thanks again, Dr. Hopson for joining us today. Could you describe for us what the disaccharidase test is?   (02:32): Thank you for that great description. For this testing. What specimen is required?   (02:58): Can You provide a brief overview and intended use of this testing?   (04:16): Could you specifically state how this test helps...

Lab fee reimbursement: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D. discuss a recent report to Congress that outlined potential laboratory fee reimbursement changes, and what that could mean for labs going forward.

Kelch-11: Divyanshu (Div) Dubey, M.B.B.S.

(00:32) Dr. Dubey, could you just tell the audience a little bit about yourself and your background? (01:56)  No one knows (better) what tests are necessary for these auto-immune patients than our lab directors who are doing really both things, seeing patients and working in the lab, so I think that's a really unique thing we want to highlight, right?   (03:11)  Can you maybe describe a little bit about that process? Because I think it will help our audience understand what that...

The Current State of COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D. review where the pandemic stands now, and discuss concerns that continue to linger regarding COVID-19 and other respiratory illnesses. 

NELL-1: Sanjeev Sethi, M.D., Ph.D.

Sanjeev Sethi, M.D., Ph.D., explains Mayo Clinic Laboratories’ newly developed test to detect neural epidermal growth factor-like 1 protein (NELL-1), a biomarker for membranous nephropathy (MN). The immunohistochemistry assay examines tissue samples for NELL-1 antigen, which are found in 10% to 15% of MN patients. Discovered by Dr. Sethi in 2017, NELL-1 is the second most common antigen associated with MN and is correlated with underlying malignancy.

Leading in Laboratory Medicine: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly update. In this episode, Dr. Morice explains his dual leadership role and how engaging in the business of a reference laboratory informs his work within academic medicine.

West Nile virus PCR testing: Bobbi Pritt, M.D.

(00:31): But before we get started, Dr. Pritt, could you provide our listeners with a little bit about you and your background?   (01:22): Can you provide a brief overview and intended use of this testing?   (03:16): Could you describe what clinical action is enabled by the results of this test?   (05:31): Now let's discuss which patients should have this testing and when should it be performed?’   (06:56): Can you now explain, how does this test improve upon previous t...

MayoComplete Solid Tumor Panel: Kevin C. Halling, M.D., Ph.D.

(00:31): Before we get started, Dr. Halling, could you provide us with a little bit about you and your background?   (01:11): Would you like to give us a basic summary of this test? (02:43): So in talking about patients, can you tell us which patients should have this testing? And when it is typically performed?   (05:01): Do you want to talk about some of the guidelines that were used to shape the genes included in this panel?   (05:36): Can you tell us a bit about the ...

Mayo Clinic, Thermo Fisher Collaboration: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, hosts this episode of the "Answers From the Lab" podcast. He’s joined by Gianluca Pettiti, senior vice president and president of specialty diagnostics at Thermo Fisher Scientific to discuss their organizations’ collaboration and its value for patients.

Laboratory Medicine After COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the future of laboratory medicine in a post-pandemic world.

TMA: Meera Sridharan, M.D., Ph.D.

(00:32): Before we get started, I'm really interested, could you give me a little bit of background on yourself and, uh, just where you work at Mayo Clinic?   (01:31): So before we start talking about the tests, can you just tell me a little bit about TMA and in that disease state itself?   (03:08): As we talk very specifically about this testing, so can you give me a brief overview of the assays we're using here at Mayo clinic to diagnose this disease state?   (05:12): So...

Mayo Clinic Laboratories: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., explain Mayo Clinic Laboratories, review its history, and describe how its work furthers Mayo Clinic’s mission.

Lab Innovation During COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., reflect on the dramatic advances that have taken place in laboratory medicine during the pandemic and what those changes might mean for the future.

Autoimmune Profile Updates: Andrew McKeon, M.B., B.Ch., M.D.

(00:41)  Before we get started talking about the panels, Dr. McKeon, could you provide a little background about yourself and your role here at Mayo Clinic?   (01:23)  I think it's important for our audience to know that you're both seeing patients and working in the lab, which helps us at Mayo Clinic to have a real understanding of what patients and physicians need to get an accurate diagnosis. Is that right? (02:09)  I know there's a lot of panels that are impacted, Dr. McKeon. ...

COVID-19 Vaccine Safety: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the safety of COVID-19 vaccines in light of the recent pause in distribution of the Johnson & Johnson vaccine.

COVID-19 Testing Update: Joseph Yao, M.D.

(00:55)  Can you tell us what you've been working on since last May?   (03:19)  How many assays did you end up validating just for detection of that single virus?    (04:36)  How many specimens at the peak of the pandemic were you able to test in one day?     (05:29)  So can you tell us a little bit more about this test that you're using for sequencing?    (08:18)  How would a clinician who orders this test then use the results to change how they're caring for the patient?   (1...

Vaccine Passports: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss vaccine passports. They review how proof of vaccination could be used along with other tools, like testing, to help curb the spread of COVID-19.

Myasthenia Gravis: Christopher Klein, M.D.

(00:34) I'm joined here today by Dr. Chris Klein. Sir, would you mind introducing yourself to our audience and telling them a little bit about your background?   (1:19) I don't want this to be a review of the paper, sir, but could you just give maybe a recap of one or some of the key takeaways?   (5:59) It was one of the first tests discovered, but we're not satisfied with the status quo and we continue to look for ways to make it better?   (6:41) Can you just help the audienc...

COVID-19 Vaccine Hesitancy: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., take a look at issues contributing to COVID-19 vaccine hesitancy. They address common myths surrounding the vaccines and discuss vaccine safety.

The Path to Leadership: Dr. Bill Morice

William Morice II, M.D., Ph.D., joins the "Answers From the Lab" podcast for his weekly leadership update. This week, Dr. Morice talks with Bobbi Pritt, M.D., about his career and the path he took to his current role as chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories.

Female Leadership at Mayo Clinic: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. March is Women's History Month, and in this episode, Dr. Morice and Bobbi Pritt, M.D., mark the occasion by discussing the legacy of female leaders at Mayo Clinic.

The Future of Lab Medicine Beyond COVID-19: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., consider how laboratory medicine will continue to evolve to meet health care needs beyond the COVID-19 pandemic.

How COVID-19 Changed the Future of Lab Medicine: Dr. Bill Morice

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss the changing face of laboratory medicine in the time of COVID-19.

Paraneoplastic Vision Loss Evaluation: Andrew McKeon, M,B., B.Ch., M.D.

(00:43)  Could you please provide us with a little background on yourself, sir?     (01:05)  So Dr. McKeon, can you just give us a brief overview on what this test is?   (02:18)  And you mentioned the CRMP-5 antibody and recoverin antibody. Are those the only two antibodies involved in this particular evaluation?   (02:43)  So those two antibodies, are they both tested up front ? And then, if so, are there any reflexes in this evaluation?   (03:25)  What will the results look ...