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Answers from the Lab

312 episodes - English - Latest episode: 20 days ago -

A Mayo Clinic curated podcast sharing Mayo Clinic knowledge and advancements on the state of testing, science, and people who are making it happen behind the scenes.

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Episodes

Perspectives from Washington, D.C.: Bill Morice, M.D., Ph.D.

November 16, 2023 07:00 - 14 minutes - 19.6 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss key takeaways from Dr. Morice’s recent visit in Washington, D.C.  Their discussion includes: How device manufacturers are evolving and collaborating within the changing landscape. The importance of submitting comments in response to th...

RNA test identifies large B-cell lymphoma subtypes: Lisa Rimsza, M.D.

November 14, 2023 07:00 - 10 minutes - 15 MB

Lisa Rimsza, M.D., explains how Mayo Clinic Laboratories' unique PM3CX test can accurately define subtypes of large B-cell lymphoma. Precise diagnosis is critical to choosing appropriate chemotherapy for these cancers. Speaker 2: (00:32)  Could you provide a brief background about yourself?   Speaker 2: (01:12)  Would you give us an overview of the PM3CX test?   Speaker 2: (03:02)  Which patients should have this testing?    Speaker 2: (05:14)  Is this test qualitative and RN...

Safeguards for AI in Healthcare: Bill Morice, M.D., Ph.D.

November 09, 2023 07:00 - 10 minutes - 14.7 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss strategies for responsible innovation and how new standards for artificial intelligence (AI) safety will impact laboratory medicine and diagnostics. Their discussion includes: Highlights of the Executive Order issued by President Biden ...

A Possible Cure for Sickle Cell Disease: Bill Morice, M.D., Ph.D.

November 02, 2023 06:00 - 15 minutes - 21 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the recent news of a possible cure for sickle cell disease, as well as gene editing therapies and their impact on the laboratory.  Their discussion includes: Characteristics of sickle cell disease and current testing and treatment optio...

Opportunities Around At-Home Testing: Bill Morice, M.D., Ph.D.

October 26, 2023 06:00 - 14 minutes - 20 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the role and expansion of at-home testing.  Their discussion includes: How home test kits for COVID-19 led to the expansion of at-home tests and telehealth options across the health industry. Understanding from a laboratory perspective t...

How AI Can Add Value to Laboratory Medicine: Bill Morice, M.D., Ph.D.

October 19, 2023 06:00 - 13 minutes - 18.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss how artificial intelligence (AI) has become a disruptive technology in the field of laboratory medicine, and how it can add value to patient care. Their discussion includes: How the conversation around AI and laboratory medicine began, ...

Transformative Technologies: Bill Morice, M.D., Ph.D.

October 12, 2023 06:00 - 11 minutes - 16.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss current focus areas found across the diagnostics industry and what transformative technologies are being explored around the world. Their discussion includes: What international laboratories and diagnostics companies are working on duri...

Proposed Regulations for Laboratory Developed Tests: Bill Morice, M.D., Ph.D.

October 05, 2023 06:00 - 11 minutes - 16.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the U.S. Food and Drug Administration’s (FDA) recently proposed rule that if finalized, would phase out its current enforcement discretion used for laboratory developed tests (LDTs), and regulate all laboratory tests as medical devices re...

Seasonal Outlook of Respiratory Viruses: Matthew Binnicker, Ph.D.

September 28, 2023 06:00 - 15 minutes - 21.3 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory at Mayo Clinic, to discuss the seasonal outlook of respiratory viruses, including influenza, COVID-19, and respiratory syncytial virus (RSV). Specific topics of discussion include: What respiratory viruses are currently circulating, and what we might expect...

Circulating Strains of COVID-19: Bill Morice, M.D., Ph.D.

September 21, 2023 06:00 - 11 minutes - 15.3 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the uptick of COVID-19 cases and the strains of the virus that are currently circulating. Their discussion includes: COVID-19 variants and how their mutations affect transmission. Lessons learned throughout the last few years with COVI...

What to Know About Leprosy: Nancy Wengenack, Ph.D.

September 14, 2023 06:00 - 13 minutes - 18.7 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Nancy Wengenack, Ph.D., director of the Mycology and Mycobacteriology Laboratories at Mayo Clinic, to talk about leprosy and why it’s been in the news recently. Leprosy, also known as Hansen’s disease, is a rare infectious disease caused by the bacteria Mycobacterium leprae. Specific topics of discussion include: How leprosy i...

Flea-borne Typhus: Elitza Theel, Ph.D.

August 31, 2023 06:00 - 11 minutes - 16.5 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic. They talk about murine typhus, also known as flea-borne typhus, and the recent increase in cases in Los Angeles County and Texas. Specific topics of discussion include: How flea-borne typhus is transmitted to humans and common symptoms...

Opioid Addiction and Substance Abuse Testing: Paul Jannetto, Ph.D.

August 24, 2023 06:00 - 22 minutes - 30.3 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Paul Jannetto, Ph.D., director of the Clinical and Forensic Toxicology Lab, Clinical Mass Spectrometry Lab, and Metals Lab at Mayo Clinic. Dr. Pritt and Dr. Jannetto discuss the current state of the opioid crisis in the United States, its impact on public health, and the important role of laboratory testing in addiction medicine...

Summertime Pathogens: Bill Morice, M.D., Ph.D.

August 17, 2023 06:00 - 10 minutes - 14.6 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss pathogens commonly found in the summertime that can cause disease and illness, and how to protect against them. Their discussion includes: Mosquito-borne and tick-borne diseases, their symptoms, and how to prevent bites. The U.S. Envir...

Modern-day Outbreaks: Bill Morice, M.D., Ph.D.

August 10, 2023 06:00 - 11 minutes - 16.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the role that a strong public health lab and diagnostic testing capabilities play in preventing widespread infectious disease outbreaks. Their discussion includes: The reemergence of infectious diseases that were prevalent years ago in ...

Test for LDL subtype helps manage coronary risk: Vlad Vasile, M.D., Ph.D., and Leslie Donato, Ph.D.

August 08, 2023 06:00 - 7 minutes - 10.8 MB

Patients with elevated LDL or "bad" cholesterol face even greater risk if their levels of small dense LDL cholesterol are also high. Vlad Vasile, M.D., Ph.D., and Leslie Donato, Ph.D., explain how Mayo Clinic Laboratories' sdLDL-c assay measures concentrations of the small dense LDL subtype, to better guide clinical care. (00:32)  Could you both tell us a little about yourselves and your backgrounds?   (01:24)  Could you tell us a little bit about small dense LDL cholesterol and ...

Learning Through Teaching Global Health: Bill Morice, M.D., Ph.D.

August 03, 2023 06:00 - 11 minutes - 16.3 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss Dr. Pritt’s recent trip to Uganda where she taught a global health course as part of a Mayo Clinic-sponsored initiative to help expand knowledge around the world in global health and tropical medicine. Their discussion includes: Dr. Pri...

Panel pinpoints causes of genetic hearing loss: Nicole Boczek, Ph.D., and Melanie Meyer, M.S, CGC

August 01, 2023 06:00 - 12 minutes - 17.5 MB

Identifying a precise genetic cause of hearing loss impacts clinical management. Nicole Boczek, Ph.D., and Melanie Meyer, M.S., CGC, explain how Mayo Clinic Laboratories' updated panel yields comprehensive results for optimal patient care. (00:31)  Can you tell us a little about yourselves and your backgrounds?   (01:52)  Could you provide a brief overview of this assay?   (02:29)  Can the diagnosis lead to improved patient care?    (03:51)  When should this test be used?   ...

Pioneering Research in Autoimmune Neurology: Vanda Lennon, M.D., Ph.D.

July 27, 2023 06:00 - 22 minutes - 31.5 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Vanda Lennon, M.D., Ph.D., founder of the Neuroimmunology Laboratory and now director of the Neuroimmunology Research Laboratory at Mayo Clinic. Dr. Pritt and Dr. Lennon discuss the research and testing innovations that have led to critical advancements in the field of autoimmune neurology over the last few decades. Specific to...

Breast cancer panel halves turnaround time: Wei Shen, Ph.D.

July 25, 2023 06:00 - 10 minutes - 15.1 MB

Wei Shen, Ph.D., explains how Mayo Clinic Laboratories' new breast cancer panel provides rapid results to guide critical treatment decisions. (00:32)  Could you provide our listeners with a little bit about yourself and your background?   (01:28)  Could you give us a brief overview of the new rapid hereditary breast cancer panel?   (03:42)  Can you describe a little bit of the rationale behind the design and how it differs from similar tests?   (05:03)  Can you tell us a litt...

Dengue and Chikungunya Outbreaks: Elitza Theel, Ph.D.

July 20, 2023 06:00 - 14 minutes - 20 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, talk about dengue and chikungunya arboviral infections.  Specific topics of discussion include: Why cases of dengue and chikungunya viral infections have rapidly increased in South America. What happens when a human is infected with dengue vir...

Gynecological NGS panels offer cost-effective cancer testing: Sounak Gupta, M.B.B.S., Ph.D.

July 18, 2023 06:00 - 12 minutes - 16.9 MB

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' gynecological NGS panels provide focused assessments of gynecological cancers. The cost-effective tests fill the gap between single gene assays and large cancer panels, to inform prognosis and treatment.   (00:32)  Could you provide our listeners with a little bit about yourself and your background, please?   (01:22)  Could you give a brief overview of the new assays?   (03:55)  Can you talk a little about bot...

Malaria in the United States: Bill Morice, M.D., Ph.D.

July 13, 2023 06:00 - 9 minutes - 12.7 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss locally acquired cases of malaria that have recently occurred in Texas and Florida. Their discussion includes:  Why malaria may be reappearing after being eliminated in the United States in the 1950s. The importance of laboratory diagnos...

Urologic panels provide focused cancer testing: Sounak Gupta, M.B.B.S., Ph.D.

July 11, 2023 06:00 - 18 minutes - 25.5 MB

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' urologic panels efficiently inform prognosis and individualized cancer treatment. The carefully curated panels fill the void between single gene assays and large NGS panels. (00:32)  Could you provide our listeners with a little bit about yourself and your background, please?   (01:35)  Could you give us a brief overview of the newly developed urologic assays?   (03:51)  Can you talk a little bit more about w...

The Latest on Measles: Matthew Binnicker, Ph.D.

July 06, 2023 06:00 - 13 minutes - 19 MB

The Centers for Disease Control and Prevention (CDC) issued a recent health advisory to remind healthcare providers to be on the lookout for cases of measles and to educate patients on measles prevention.  In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory at Mayo Clinic, to discuss why measles prevention co...

Results report simplifies urine test interpretation: John Lieske, M.D.

July 04, 2023 06:00 - 10 minutes - 14.5 MB

John Lieske, M.D., explains why it's now easier for clinicians to pull information from Mayo Clinic Laboratories' urine supersaturation test report. An updated format summarizes complex information to help guide the treatment of kidney stones. (00:32)  Could you tell us a little bit about yourself and your background?   (01:28)  Could you give us a brief overview of urine supersaturation testing? How should it be used? How can it benefit providers and their patients?   (04:14) ...

FDA Oversight of Lab-Developed Tests: Bill Morice, M.D., Ph.D.

June 29, 2023 06:00 - 9 minutes - 12.9 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the latest update on the U.S. Food and Drug Administration’s (FDA) proposed rule to oversee laboratory-developed tests (LDTs) and what that could mean for laboratories. Specific topics of discussion include:  The FDA’s recent announcement...

Multigene panel provides efficient ataxia diagnosis: Angela Pickart, M.S., CGC, and Emily Lauer, M.S., CGC

June 27, 2023 06:00 - 12 minutes - 17.5 MB

Angela Pickart, M.S., CGC, and Emily Lauer, M.S., CGC, explain how Mayo Clinic Laboratories' multigene panel helps identify the cause of hereditary ataxia. Precise diagnosis of this complex movement disorder helps guide patient treatment and family screening. Show notes Speaker 3: (00:31)  Can you tell us a little about yourselves and your backgrounds?   Speaker 3: (01:33)  Why is genetic counseling so important to our doctors and patients?   Speaker 3: (03:04)  Can you give a ...

Remote Diagnostics: Bill Morice, M.D., Ph.D.

June 22, 2023 06:00 - 10 minutes - 13.9 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about the evolution of remote diagnostics and how Mayo Clinic’s remote cardiovascular monitoring services empower physicians and patients.  Specific topics of discussion include: How a comprehensive diagnostics ecosystem includes patient dat...

Updated assay guides diagnosis of autoimmune liver disease: Anne Tebo, Ph.D.

June 20, 2023 06:00 - 15 minutes - 21.9 MB

Anne Tebo, Ph.D., explains how Mayo Clinic Laboratories' updated ALDG2 assay helps with the evaluation of patients with suspected autoimmune liver disease. The panel also helps with the evaluation of liver disease of unknown etiology. Speaker 2: (00:32)  Could you provide a little bit about you and your background?   Speaker 2: (02:05)  Can you please give a brief overview of this assay?   Speaker 2: (04:12)  Which patients should have this testing and when should it be perform...

Diagnosing Lyme Disease: Bill Morice, M.D., Ph.D.

June 15, 2023 06:00 - 12 minutes - 17.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about the tick season peak that parts of the United States are experiencing, and how to diagnose and prevent Lyme disease. Specific topics of discussion include: What parts of the United States have a heavy tick and Lyme disease presence. H...

BioPharma Diagnostics: Bill Morice, M.D., Ph.D.

June 08, 2023 06:00 - 15 minutes - 22 MB

Research and discoveries in the biopharmaceutical industry drive health care innovation and lead to new therapies for patients. When laboratories collaborate with biopharma, diagnostic, and biotech companies, it creates an integrated diagnostic ecosystem that can improve global health. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and pr...

The impact of AI: Bill Morice, M.D., Ph.D.

May 25, 2023 06:00 - 16 minutes - 23.3 MB

Artificial intelligence (AI) can be an excellent tool for enhancing patient care and streamlining efficiencies in the lab. But because of its potential risks, AI must be thoughtfully and responsibly applied, both now and in the future.  In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to talk about...

West Nile virus: Elitza Theel, Ph.D.

May 18, 2023 06:00 - 17 minutes - 23.9 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, talk about West Nile virus and why laboratories and the public need to be aware as mosquitoes reemerge. Specific topics of discussion include: Why the mosquito is the deadliest animal in the world. Symptoms, testing options, and prevention str...

The progression of the diagnostic landscape: Bill Morice, M.D., Ph.D.

May 11, 2023 18:00 - 12 minutes - 17.1 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss broader changes that are unfolding in the national and global diagnostic industry, and what to expect in the coming years. Specific topics of discussion include: Reflecting on Dr. Morice’s recent participation in Executive War College and...

Endemic fungal infections in North America: Elitza Theel, Ph.D.

May 04, 2023 06:00 - 13 minutes - 18.2 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, discuss endemic fungal infections that can be found in North America, specifically blastomycosis and histoplasmosis.  Specific topics of discussion include: The basics of Blastomyces and Histoplasma fungi, which can cause serious lung infection...

A strong community of lab professionals: Bill Morice, M.D., Ph.D., and Susan Van Meter

April 27, 2023 06:00 - 23 minutes - 33 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, and special guest Susan Van Meter, president of the American Clinical Laboratory Association (ACLA). In celebration of Medical Laboratory Professionals Week, they discuss the critical role laboratories play in patient care and key legislative issues t...

Test detects autoimmune neurology disorders linked to cancer: Sean Pittock, M.D.

April 25, 2023 06:00 - 20 minutes - 27.6 MB

Sean Pittock, M.D., explains how Mayo Clinic Laboratories' novel Ma2 test aids diagnosis of autoimmune neurology disorders that are often caused by underlying cancer. Rapid diagnosis is key to preventing significant disability and disease. (00:31)  Can you provide our listeners with a little bit of background on your role at Mayo Clinic?   (01:56)  Is Ma2 an example of identifying a need in patient care and then creating a test to fill that gap?   (02:30)  Can you give us an ov...

Emerging fungal pathogens: Dr. Nancy Wengenack

April 20, 2023 06:00 - 15 minutes - 21 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Nancy Wengenack, Ph.D., director of the Mycology and Mycobacteriology Laboratories at Mayo Clinic, discuss the increased focus on fungi and why emerging fungal infections can be concerning for health care facilities. Specific topics of discussion include: How fungi work inside and outside of the body. If it’s possible for fungal infec...

Leading important industry conversations: Bill Morice, M.D., Ph.D.

April 13, 2023 06:00 - 12 minutes - 17.7 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss how representation and advocacy make a difference in regulatory outcomes. Specific topics of discussion include:  Why pathologists should be leading conversations about the future of health care. Advocating for issues facing the diagnostics industry...

IDH assay facilitates timelier leukemia treatment: Rong He, M.D.

April 11, 2023 06:03 - 8 minutes - 12.4 MB

Rong He, M.D., explains how Mayo Clinic Laboratories' IDHQ test speeds therapeutic decision making for adults with acute myeloid leukemia, or AML. The standalone assay yields faster results than next generation sequencing. (00:32)  Would you provide a brief background of yourself?   (01:42)  Could you give an overview of the IDHQ test?   (02:25)  Is there anything more you'd like to touch on about the droplet digital PCR approach and high sensitivity?   (03:09)  Why are IDH1 ...

Neurofilament light chain: Bjorn Oskarsson, M.D.

April 06, 2023 06:00 - 13 minutes - 18.3 MB

In this test-specific episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and Bjorn Oskarsson, M.D., a neurologist at Mayo Clinic’s Florida campus, discuss how the neurofilament light chain test available through Mayo Clinic Laboratories helps physicians diagnose neurological disease and assess neuronal damage. Specific topics of discussion include: Benefits of the neurofilament light chain test th...

Approaching tick season: Bill Morice, M.D., Ph.D.

March 30, 2023 06:00 - 6 minutes - 8.47 MB

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss the increasing rates of tick-borne diseases and how to test for and prevent them. They also discuss what to watch from a federal legislative standpoint now that Congress is back in session.

An efficient, cost-effective, fungal testing alternative: Elitza Theel, Ph.D.

March 28, 2023 06:00 - 12 minutes - 16.7 MB

Elitza Theel, Ph.D., explains how Mayo Clinic Laboratories' unique Histoplasma and Blastomyces test provides cost-effective evaluation for fungal infections that cause pulmonary illness. The assay reliably detects both Histoplasma and Blastomyces pathogens in a single test. (00:32) Will you please give us a brief introduction of yourself and your role at Mayo Clinic?   (01:34)  Can you tell us which specific group of patients this test would be best suited for, how a provider wo...

Test assesses all inherited Parkinson's disease genes: Zhiyv (Neal) Niu, Ph.D., and Rodolfo Savica, M.D., Ph.D.

March 21, 2023 06:00 - 10 minutes - 14.7 MB

Zhiyv (Neal) Niu, Ph.D., and Rodolfo Savica, M.D., Ph.D., explain why Mayo Clinic Laboratories' gene panel is the most comprehensive test available for inherited Parkinson's disease. The new panel covers all mutations known to cause the condition — or increase the risk of developing it. (01:37)  Can you give us a brief overview of the inherited Parkinson's disease gene panel, and when it would be used, Dr. Niu?   (02:31)  Dr. Savica, can you give us a brief overview of the inheri...

Neuromuscular gene panel provides comprehensive analysis: Zhiyv (Neal) Niu, Ph.D., and Christopher Klein, M.D.

March 14, 2023 06:00 - 8 minutes - 12.1 MB

(00:31)  Dr. Niu, could you provide us with a little bit of your background? (01:03)  Dr. Klein, could you provide us with a little bit of your background?   (01:40)  Would you give us a brief overview of the new panel?   (02:49)  Dr. Klein, could you give us a simple background of what you see going on in this space?   (03:33)  Which patients should have this testing, and when should it be performed? (04:49)  Are there alternatives available, and how do they compare with th...

Amplifying the voice of the lab during policymaking: Dr. Bill Morice

March 09, 2023 07:00 - 13 minutes - 19 MB

Many laboratorians are not patient-facing. So, while laboratories are critical to patient care, they may lack visibility when it comes to policymaking.  In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, and William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, discuss their leadership roles in national advocacy organizations and the importance of laboratorian engag...

Whole genome sequencing streamlines diagnosis: Nicole Boczek, Ph.D., and Sarah Barnett, M.S., CGC

February 28, 2023 07:00 - 18 minutes - 25 MB

(00:31)  Would each of you share a little bit about yourselves and your backgrounds?   (01:47)  Could you provide us with an overview of what the WGSDX test is?   (02:26)  How is that different from other genetic tests, like exome or microarray?   (03:56)  Tell us more about who benefits from these tests.   (07:17)  Is this test recommended by expert groups?   (09:10)  How do providers go about ordering this test, and what sample types are accepted?   (11:12)  What type o...