Latest Medical research Podcast Episodes

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Jak2V617F clonal hematopoiesis promotes arterial thrombosis; Staphylococcus aureus infection in Sézary syndrome; clinical features of RAC2-related immunodeficiency

Blood Podcast - April 13, 2024 04:00 - 26 minutes ★★★★ - 42 ratings
In this week's episode we’ll discuss the mechanism by which Jak2V617F clonal hematopoiesis promotes arterial thrombosis, discuss how Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome, and learn more about the clinical and functional features of RAC2-rela...

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Re-Release: How AI is helping to predict death and complications after heart procedures

Health Lab - April 05, 2024 17:10 - 3 minutes ★★★★ - 5 ratings
This episode first aired on January 19, 2024. It showed high levels of accuracy at predicting death, major bleeding events and the need for blood transfusion. Visit Health Lab to read the full story. The BMC2 Probability of Events Following PCI application can be found here. The transcript fo...

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Molecular mimicry in aplastic anemia; emicizumab prophylaxis in infants with hemophilia; hydroxyurea reduces infections in SCA

Blood Podcast - April 04, 2024 16:30 - 19 minutes ★★★★ - 42 ratings
In this week's episode we'll discuss molecular mimicry in aplastic anemia, novel experiments show that antigens associated with viral infections can mimic epitopes presented on hematopoietic progenitor cells. Then, we'll learn about prophylaxis with subcutaneous emicizumab in infants wi...

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Re-Release: The 3 S's of Seizure First Aid

Health Lab - March 29, 2024 13:17 - 5 minutes ★★★★ - 5 ratings
This episode first aired on 10/20/2023. For kids with epilepsy, seizures can strike at any time. Here’s what you can do to help. Educational resources for epilepsy and seizures Epilepsy Foundation Training and Education Michigan Medicine Comprehensive Pediatric Epilepsy Care Visit Health La...

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Review Series on the Influence of the Tumor Microenvironment on the Pathogenesis of B-Cell Lymphomas

Blood Podcast - March 28, 2024 18:30 - 32 minutes ★★★★ - 42 ratings
In this bonus episode of Blood Podcast, Associate Editor, Dr. Freda Stevenson is joined by Drs. Karin Tarte, Andrea Radtke, and Leandro Cerchietti to discuss the Review Series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas. Find the full review ...

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Free light chain mass spectrometry in diagnosis and monitoring of AL amyloidosis; T cells of AML patients in remission have distinct RNA signatures; and protective effect of ADAMTS13 in sickle cell mice depends on von Willebrand factor clearance

Blood Podcast - March 28, 2024 17:00 - 22 minutes ★★★★ - 42 ratings
In this week's episode we’ll discuss the findings from a study assessing the utility of free light chain mass spectrometry in AL amyloidosis, learn more about distinct single-cell RNA-sequencing signatures of bone marrow T cells of AML patients in remission after an allogeneic stem cell...

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Episode 28: Introduction to Vivistim-Paired Vagus Nerve Stimulation Therapy

Evidence To Excellence: News In Neuroplasticity and Rehab - March 28, 2024 16:00 - 45 minutes
Host Polly Swingle is joined by Mark Pedziwiatr MS, OTR/L, ATP, to talk about Vivistim. Vivistim is a paired vagus nerve stimulation therapy that enhances the effects of neuroplasticity. Vivistim is FDA approved for chronic ischemic stroke survivors with ongoing upper limb deficits. Listen in to...

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Re-Release: A smart watch that could help your heart

Health Lab - March 22, 2024 12:00 - 3 minutes ★★★★ - 5 ratings
This episode originally aired on December 15, 2023. The device would be the first clinical-grade, diagnostic wrist-worn device for long term Afib monitoring. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michig...

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Eculizumab in transplant-associated thrombotic microangiopathy; reclassifying malignant monocytosis; targeting tissue factor in antiphospholipid syndrome

Blood Podcast - March 21, 2024 16:30 - 20 minutes ★★★★ - 42 ratings
In this week's episode we'll discuss eculizumab in stem cell transplant-associated thrombotic microangiopathy. Then, we'll learn about reclassifying malignant monocytosis, these newly classified cases have distinct mutational and transcriptional profiles. Finally, we'll hear about targe...

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Managing Chronic Pain for Patients with Long COVID

Health Lab - March 15, 2024 15:23 - 3 minutes ★★★★ - 5 ratings
Therapies for pain conditions like fibromyalgia provide clues for helping those with long COVID. Michigan Medicine resource for patients with post-acute sequelae of COVID-19, also known as long COVID. Visit Health Lab to read the full story. The transcript for this episode can be found here. ...

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Identification of rare relapse-initiating stem cells post-transplantation; interferon α impairs erythropoiesis in sickle cell disease; TNFα promotes clonal dominance of KIT D816V+ cells in mastocytosis

Blood Podcast - March 14, 2024 16:30 - 22 minutes ★★★★ - 42 ratings
In this week's episode we’ll learn more about rare relapse-initiating stem cells in patients with MDS or AML in complete remission post-transplantation, discuss the role of interferon α in erythropoiesis in sickle cell disease, and learn more about how TNFα promotes clonal dominance of ...

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Investigating How Dermal Injections Impact Aging Skin.

Health Lab - March 08, 2024 13:00 - 1 minute ★★★★ - 5 ratings
A new study examines dermal injections and their impact on skin aging. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine Department of Communication. Michigan Medicine is the academic medical cente...

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Investigating How Dermal Injections Impact Aging Skin

Health Lab - March 08, 2024 13:00 - 1 minute ★★★★ - 5 ratings
A new study examines dermal injections and their impact on skin aging. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine Department of Communication. Michigan Medicine is the academic medical cente...

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How PAR2 signaling drives thrombo-inflammation; pretransfusion hemoglobin levels linked to survival in beta-thalassemia; etoposide is better than its reputation in primary HLH

Blood Podcast - March 07, 2024 17:30 - 17 minutes ★★★★ - 42 ratings
In this week's episode we'll discuss PAR2-biased signaling in thrombo-inflammation. Then, we'll learn about how hemoglobin levels are linked to survival in transfusion-dependent beta-thalassemia. Finally we'll hear about how etoposide is better than its reputation in primary HLH—hemopha...

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Re-Release: New Research on Gender-Affirming Testosterone and Fertility

Health Lab - March 01, 2024 16:17 - 4 minutes ★★★★ - 5 ratings
This episode first aired on 11/10/23. Evidence can help inform fertility care for transgender and gender diverse people who wish to become parents. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicin...

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Brentuximab vedotin plus dacarbazine or nivolumab in classical Hodgkin lymphoma; loss of CD20 causes resistance to mosunetuzumab in r/r B-cell lymphomas; trogocytosis as a driver of RBC antigen loss

Blood Podcast - February 29, 2024 17:30 - 23 minutes ★★★★ - 42 ratings
In this week's episode we’ll discuss the findings from a prospective trial of brentuximab vedotin with dacarbazine or nivolumab in older patients with classical Hodgkin lymphoma, learn more about CD20 antigen loss as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-ce...

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Episode 27: Introduction to Transcranial Magnetic Stimulation (TMS)

Evidence To Excellence: News In Neuroplasticity and Rehab - February 28, 2024 20:00 - 50 minutes
Host Polly Swingle is joined by Dr. Nick Mischel, MD, PhD, and Steve Watts, MOT, OTR/L, CSRS, CBIS, AIB-VR, to discuss Transcranial Magnetic Stimulation (TMS). This procedure is FDA approved to improve symptoms of major depression, obsessive-compulsive disorder (OCD), migraines, and to help peop...

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Re-Release: Saying Goodbye to UTIs

Health Lab - February 23, 2024 15:19 - 7 minutes ★★★★ - 5 ratings
This episode first aired on 12/8/23. Urinary tract infections are a pain. A doctor explains how to banish them for good. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine Department of Communicati...

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CAR T cells plus ibrutinib in relapsed/refractory MCL; targeting SGF29 in AML; diffusion-limited oxygen release from stored blood

Blood Podcast - February 22, 2024 17:30 - 18 minutes ★★★★ - 42 ratings
In this week's episode we'll discuss CAR T cells plus ibrutinib for the treatment of relapsed/refractory mantle cell lymphoma. Next, we'll learn about a new SAGA for acute myeloid leukemia. Finally, we'll hear about new evidence that oxygen delivery to tissues can become diffusion-limit...

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Access to Plan B coincides with a drastic decrease in emergency contraception-related ER visits, study shows

Health Lab - February 16, 2024 15:54 - 4 minutes ★★★★ - 5 ratings
U.S. emergency departments see 96% fewer visits, $7.6 million less in medical costs after FDA approval of over the counter emergency contraception. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine...

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Long-term outcomes of pulmonary embolism in children and adolescents; hereditary angioedema caused by a methionine-379 to lysine substitution in kininogens; predictors of loss of MRD negativity in multiple myeloma

Blood Podcast - February 15, 2024 17:30 - 25 minutes ★★★★ - 42 ratings
In this week's episode we’ll report on the findings from a study evaluating the long-term outcomes of pulmonary embolism in children and adolescents, discuss a new mechanism for hereditary angioedema caused by a methionine-379 to lysine substitution in kininogens, and learn more about p...

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Re-Release: Increased Travel Barriers Make it Harder to Access Gender-Affirming Care for Trans Youth

Health Lab - February 09, 2024 14:22 - 3 minutes ★★★★ - 5 ratings
This episode first aired in July 2023. Rapid state law changes mean 1 in 4 youth now live more than 4 hours from the closest clinic that could provide medications and hormones, and 1 in 4 clinics must stop offering this service. Visit Health Lab to read the full story. The transcript for this...

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Extended follow-up of axi-cel in indolent NHL; platelets help clear senescent RBCs; novel risk stratification strategy for CNS lymphoma

Blood Podcast - February 08, 2024 17:30 - 18 minutes ★★★★ - 42 ratings
In this week's episode we'll discuss extended follow-up from the ZUMA-5 trial of axicabtagene ciloleucel, or axi-cel. Then we'll learn about the role of platelets in binding and clearing senescent red blood cells. Finally, we'll hear about a new risk stratification strategy for lymphoma...

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Re-Release: A new pill for postpartum depression

Health Lab - February 02, 2024 18:39 - 4 minutes ★★★★ - 5 ratings
The fast-acting pill, paired with psychosocial treatment, offers a comprehensive treatment plan, but price concerns remain. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine Department of Communica...

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Lisocabtagene maraleucel in relapsed or refractory large B-cell lymphoma; reciprocal stabilization of coagulation factor XIII-A and -B subunits; inotuzumab ozogamicin for MRD in ALL

Blood Podcast - February 01, 2024 17:30 - 22 minutes ★★★★ - 42 ratings
In this week's episode we’ll discuss the findings from a two-year follow-up study of lisocabtagene maraleucel in relapsed or refractory large B-cell lymphoma, learn more about how reciprocal stabilization of coagulation factor XIII-A and -B subunits influences plasma FXIII concentration...

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Episode 26: The Benefits Of Yoga And The Connection Of Breathe To Movement

Evidence To Excellence: News In Neuroplasticity and Rehab - January 30, 2024 20:00 - 57 minutes
Host Polly Swingle is joined by Brent Rieli, E-RYT-500 and Sheri Rieli, RYT-500, Co-Founders of the Plymouth Yoga Room to talk everything yoga and their journey in creating their studio in downtown Plymouth, Michigan.  Topics discussed include studies and statistics on the current state of the p...

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Re-Release: The Importance of Keeping Your Teeth Healthy During Pregnancy

Health Lab - January 26, 2024 16:20 - 4 minutes ★★★★ - 5 ratings
This episode first aired on September 22, 2023. Oral care is important, and your prenatal care should involve a trip to the dentist. Visit Health Lab to read the full story. The transcript for this episode can be found here. Health Lab is brought to you by the Michigan Medicine Department of...

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Maternal anticancer drug exposure and leukemia; PIEZO1-TMEM16F coupling in hereditary xerocytosis; NPM1 MRD during venetoclax therapy in NPM1-mutated AML

Blood Podcast - January 25, 2024 17:30 - 18 minutes ★★★★ - 42 ratings
In this week’s episode, we’ll discuss the association between occupational exposure to anticancer agents in a parent and subsequent cancer in a child. Then we’ll learn about deciphering and disrupting the activation of PIEZO1 in hereditary xerocytosis. Finally, we’ll hear about the asse...

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How AI is helping to predict death and complications after heart procedures

Health Lab - January 19, 2024 18:17 - 3 minutes ★★★★ - 5 ratings
It showed high levels of accuracy at predicting death, major bleeding events and the need for blood transfusion. Visit Health Lab to read the full story. The BMC2 Probability of Events Following PCI application can be found here. The transcript for this episode can be found here. Health Lab i...

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TCRαβ/CD19-cell depleted haploHSCT for pediatric leukemia; malignancy-associated hemophagocytic lymphohistiocytosis in Sweden; the bone marrow as the primary site of thrombopoiesis

Blood Podcast - January 18, 2024 17:30 - 21 minutes ★★★★ - 42 ratings
In this week's episode we’ll discuss the findings from a prospective trial of TCRαβ/CD19-cell depleted HLA-haploidentical transplantation to treat pediatric acute leukemia, learn more about the incidence, clinical characteristics, and survival of malignancy-associated hemophagocytic lym...