Latest Mass spectrometry Podcast Episodes

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The Regulatory Landscape of Laboratory Developed Tests (LDT): A Laboratorian Perspective

MSACL - November 14, 2023 17:00 - 56 minutes ★★★★★ - 1 rating
The FDA released a proposed LDT rule and stated it will “end its enforcement discretion” of LDTs. Previously, the FDA explored other avenues for regulating LDTs. We will discuss questions relevant to the draft rule and implications to laboratory medicine, including, but not limited to: - What are...

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MSACL 2023 : A Chat with Jennifer Van Eyk on her Distinguished Contribution Award Lecture

MSACL - April 05, 2023 16:30 - 12 minutes ★★★★★ - 1 rating
Dustin Bunch chats with Jennifer Van Eyk on the fine points of her Distinguished Contribution Award lecture from the previous evening. Recorded onsite at MSACL 2023 Monterey in the Exhibit Hall.

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MSACL 2023 : A Chat with Tim Collier on his Michael S Bereman Award Lecture

MSACL - April 05, 2023 16:00 - 11 minutes ★★★★★ - 1 rating
Dustin Bunch chats with Tim Collier on some of the nuances of his Michael S Bereman Award for Innovative Clinical Proteomics lecture from the previous afternoon. Recorded onsite at MSACL 2023 Monterey in the Exhibit Hall.

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The MetaProteomics Initiative : The Cornerstone of Comprehensive Molecular Analysis of the Microbiome Ecosystem

MSACL - March 16, 2023 17:00 - 41 minutes ★★★★★ - 1 rating
Through connecting genomic and metabolic information, metaproteomics is an essential approach for understanding how microbiomes function in space and time. The international metaproteomics community is delighted to announce the launch of the Metaproteomics Initiative (www.metaproteomics.org), the...

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Paper Spray Mass Spectrometry in Clinical Application

MSACL - December 15, 2022 00:00 - 34 minutes ★★★★★ - 1 rating
An interview with Lindsey Kirkpatrick, DO, PhD and Nicholas Manicke, PhD discussing the technology behind, and development of, Paper Spray technology, as well as its place in the clinical lab. Read the companion article in JMSACL, Development and validation of a paper spray mass spectrometry meth...

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The triple quadrupole: Innovation, serendipity and persistence

MSACL - November 02, 2022 21:00 - 42 minutes ★★★★★ - 1 rating
An interview with Richard Yost, co-developer of the Triple Quadrupole Mass Spectrometer. How it was developed and why. Read the companion article in JMSACL at https://www.sciencedirect.com/science/article/pii/S2667145X22000141

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JMSACL Journal Club : Supervised Machine Learning for Mass Spectrometry Data Analysis: Experts' Opinion

MSACL - March 01, 2022 18:00 - 58 minutes ★★★★★ - 1 rating
We will be talking with Thomas Durant and Edward Lee about recent advances in machine learning (ML) for mass spectrometry (MS) data analysis. The primary focus will be the alignment of these two fields (ML and MS) and how this offers a promising synergy that can be used to optimize workflows, im...

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Fireside Chat with Christopher Rose on Single Cell Proteomics

MSACL - September 29, 2021 17:00 - 1 hour ★★★★★ - 1 rating
Christopher Rose shares his thoughts on single cell proteomics.

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JMSACL Journal Club : Understanding X-Chromosome Deletion Disorder using metabolomics and lipidomics

MSACL - August 20, 2021 05:26 - 1 hour ★★★★★ - 1 rating
X linked disorders are considerably rare and research analysing human samples is under-represented. Research undertaken in this study used neural progenitor cells from an afflicted patient to begin exploring this rare disorder. While most experimental work focuses on the neurodevelopmental impac...

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Novel Techniques using Silicon (in silico) and Gold to Improve Imaging Results

MSACL - April 29, 2021 16:30 - 1 hour ★★★★★ - 1 rating
Untargeted small molecule machine learning for MSI Cameron Shedlock (until 14:00) Mass spectrometry imaging returns large dimensionally complex datasets. Traditional analysis in imaging utilizes a mindset focused on target molecule identification that parses data with a narrow view of molecula...

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JMSACL Journal Club with Benjamin Owusu

MSACL - April 23, 2021 17:03 - 59 minutes ★★★★★ - 1 rating
A presentation and discussion with Dr. Owusu on his recently published paper in JMSACL entitled Development and validation of a novel LC-MS/MS assay for C-peptide in human serum.

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Electrochemical Strategies in ESI-MS for Lipid Analysis

MSACL - April 22, 2021 07:00 - 1 hour ★★★★★ - 1 rating
Lipids play a vital role in maintaining cellular functions. Altered lipid metabolism is currently considered a hallmark of many diseases, which highlights the importance of the characterization of lipid composition in understanding, diagnosing, and treating pathologies. Discrimination of isomeri...

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Reference data-driven metabolomics and application to nutrition research

MSACL - April 20, 2021 17:00 - 1 hour ★★★★★ - 1 rating
Surveying the food-associated compounds detected in clinical samples, we can differentiate patients with specific diet types, such as predominantly animal protein- versus plant-based diet. In addition, we can identify specific foods associated with clinical outcomes in disease cohorts. With its ...

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Empirically tracking the exposure of human plasma & serum samples to thawed conditions

MSACL - April 06, 2021 17:00 - 1 hour ★★★★★ - 1 rating
This presentation will described the concept, methodology, validation and performance characteristics of a 10-µL, dilute-and-shoot, intact-protein mass spectrometric assay of albumin proteoforms called “Delta-S-Cys-Albumin” that serves as an endogenous marker of P/S exposure to thawed conditions...

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Getting going with MS (4) : Josh attempts method validation

MSACL - March 09, 2021 18:00 - 1 hour ★★★★★ - 1 rating
This session will outline the studies conducted and planned in order to complete validation of a mass spectrometry method in a CAP-accredited, clinical laboratory. While accuracy and precision and reportable range will be addressed, particular attention will be paid to the additional validation ...

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Getting going with MS (3) : Josh analyzes peaks

MSACL - February 11, 2021 16:00 - 1 hour ★★★★★ - 1 rating
Unlike conventional immunoassays which provide simple (and often incorrect!) results, mass spectrometers provide a plethora of data for every peak- qualifier ions, internal standard areas, retention times, peak shapes, etc. This data, often termed metadata, can help clinical laboratories evaluat...

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Getting going with MS (2) : Josh learns chromatography

MSACL - January 07, 2021 18:00 - 1 hour ★★★★★ - 1 rating
What do we want? Good chromatography! How do we get it? We don’t know! Columns, maybe? Good chromatography is essential to any LC-MS/MS method. Setting it up is often one of the earlier steps in developing a new method. While it can be an iterative process, setting up good chromatographic condi...

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Getting going with mass spectrometry : Josh learns chromatography

MSACL - January 07, 2021 18:00 - 1 hour ★★★★★ - 1 rating
What do we want? Good chromatography! How do we get it? We don’t know! Columns, maybe? Good chromatography is essential to any LC-MS/MS method. Setting it up is often one of the earlier steps in developing a new method. While it can be an iterative process, setting up good chromatographic condi...

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Vitamin D and Immune Function

MSACL - December 08, 2020 18:00 - 1 hour ★★★★★ - 1 rating
Prof. Hewison’s group is at the forefront of research linking vitamin D and the immune system, with implications for a wide range of clinical disorders including infectious, inflammatory and autoimmune disease. Current studies are focused on the analysis of vitamin D-insensitivity in T lymphocyt...

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Getting going with MS (1) : Josh installs a mass spectrometer

MSACL - October 22, 2020 17:00 - 50 minutes ★★★★★ - 1 rating
This session will serve as an introduction to a 4 part series in which Dr. Hayden will invite attendees to witness in real time his journey bringing mass spec testing to a clinical lab. During these interactive sessions, attendees will be encouraged to help troubleshoot, and offer advice as des...

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Getting going with mass spectrometry: Josh installs a mass spectrometer

MSACL - October 22, 2020 17:00 - 50 minutes ★★★★★ - 1 rating
This session will serve as an introduction to a 4 part series in which Dr. Hayden will invite attendees to witness in real time his journey bringing mass spec testing to a clinical lab. During these interactive sessions, attendees will be encouraged to help troubleshoot, and offer advice as des...


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Analytical Chemistry Podcast - November 2016

Analytical Chemistry Podcast - November 10, 2016 17:30 - 10 minutes ★★★★ - 9 ratings
Interview with Vladimír Havlíček


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Analytical Chemistry Podcast - September 2016

Analytical Chemistry Podcast - September 06, 2016 17:30 - 12 minutes ★★★★ - 9 ratings
Interview with Stephen Jacobson, Josh Baker, Dave Kysela and Yves Brun




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Analytical Chemistry Podcast - April 2016

Analytical Chemistry Podcast - April 06, 2016 17:30 - 15 minutes ★★★★ - 9 ratings
Interview with Lingjun Li and Erin Gemperline

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Analytical Chemistry Podcast - March 2016

Analytical Chemistry Podcast - March 01, 2016 17:30 - 19 minutes ★★★★ - 9 ratings
Interview with Marcos Eberlin and Sebastiaan Teunissen

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