TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes
283 episodes - English - Latest episode: 2 months ago -Welcome to TheSugarScience Podcast where our mission is to highlight and connect researchers in the type 1 diabetes space.
The(sugar)science is an interactive digital platform founded to curate the scientific conversation among type 1 diabetes (T1D) researchers. Our goal is to expedite a cure for T1D by promoting collaboration across diverse research disciplines.
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Episodes
Episode 28: Adebola Giwa, MD, Pediatric Endocrinologist at Johns Hopkins Children’s Center
October 26, 2020 17:37 - 33 minutes - 45.4 MBIn this episode, Adebola Giwa joins Monica Westley to discuss his bench and clinical research in the type 1 diabetes space. Dr. Giwa is a research investigator in The Hamad Laboratory. His bench research is focused on identifying unconventional lymphocytes and studying their role in the pathogenesis of type 1 diabetes to possibly target them for future immunotherapies. His clinical research involves multi-center clinical trials utilizing islet cell transplants to reestablished insulin produc...
Episode 27: Daniel Espes, MD, PhD, Associate Professor at Uppsala Universitet, Sweden, Co-Founder of Digital Diabetes Analytics
October 23, 2020 16:14 - 50 minutes - 69.4 MBIn this episode, Daniel Espes joins Monica Westley to discuss his work and dedication to type 1 diabetes research. Dr. Espes is the co-founder of Digital Diabetes Analytics. The mission of Digital Diabetes Analytics is to create a bridge between diabetes data and knowledge in order to make life more flexible for everyone living with insulin treated diabetes. Interested in learning more about Dr. Espes work? Take a look at some of his recent data: ProTrans shows significant effect in Dia...
Episode 26: Lucy Walker, PhD, University College London, The Walker Lab
October 23, 2020 05:47 - 31 minutes - 43.1 MBIn this episode, Lucy Walker joins Monica Westley to discuss her research at the Walker Lab at the University College London. The group is exploring how CD4 T cell mediated immune responses are initiated and regulated. The principle research goal is to understand why immune regulation fails in certain individuals resulting in destructive autoimmune responses against self-tissues. To learn more about the Walker Lab, click on the link below! The Walker Lab Recent Publication: Follicular h...
Episode 25: Eimear Dolan, PhD, SFI Royal Society University Research Fellow and Lecturer Biomedical Engineering, National University of Ireland Galway
October 21, 2020 15:00 - 28 minutes - 39 MBIn this episode, Eimear Dolan joins Monica Westley to discuss her work with implantable medical devices for treating type 1 diabetes. In the interview she also provides some great advice for researchers. Dr. Dolan has recently been named as one of 10 global visionaries in MIT Technology Review's annual list of Innovators Under 35. Dolan and colleagues have developed a soft robotic device known as a dynamic soft reservoir to improve the longterm performance of implanted medical devices.
Episode 24: Christine Bender, PhD, La Jolla Institute for Immunology
October 21, 2020 01:37 - 27 minutes - 37.8 MBIn this episode, Christine Bender joins Monica Westley to discuss her latest research at the La Jolla Institute for Immunology in the Von Herrath Laboratory. Her major project focuses on study antigen-specific CD8 T cells, in pancreas from donors with type 1 diabetes and healthy donors. Make sure to look out for her new publication coming out soon in Science Advances in October. Want to read more about her research? Checkout the following paper linked below. Islet-Expressed CXCL10 Promo...
Episode 24: Inish O'Doherty, PhD, Executive Director, Type 1 Diabetes (T1D) and Transplant Therapeutics (TTC) Consortium at C-Path
October 12, 2020 22:46 - 24 minutes - 33.2 MBIn this episode, Inish O'Doherty joins Monica Westley to discuss his work which focuses on the collaborative selection and development of prognostic biomarkers that can be qualified as Drug Development Tools (DDT) and Novel Methodologies with the FDA and EMA, respectively. Dr. O'Doherty is the Executive Director of C-Path’s Type 1 Diabetes (T1D) and Transplant Therapeutic Consortium (TTC). To learn more about the ongoing research at C-Path, click on the link below C-Path Website
Episode 23: Inish O'Doherty, PhD, Executive Director, Type 1 Diabetes (T1D) and Transplant Therapeutics (TTC) Consortium at C-Path
October 12, 2020 22:46 - 24 minutes - 33.2 MBIn this episode, Inish O'Doherty joins Monica Westley to discuss his work which focuses on the collaborative selection and development of prognostic biomarkers that can be qualified as Drug Development Tools (DDT) and Novel Methodologies with the FDA and EMA, respectively. Dr. O'Doherty is the Executive Director of C-Path’s Type 1 Diabetes (T1D) and Transplant Therapeutic Consortium (TTC). To learn more about the ongoing research at C-Path, click on the link below C-Path Website
Episode 23: Christine Bender, PhD, La Jolla Institute for Immunology
October 09, 2020 18:11 - 27 minutes - 37.8 MBIn this episode, Christine Bender joins Monica Westley to discuss her latest research at the La Jolla Institute for Immunology in the Von Herrath Laboratory. Her major project focuses on study antigen-specific CD8 T cells, in pancreas from donors with type 1 diabetes and healthy donors. Make sure to look out for her new publication coming out soon in Science Advances in October. Want to read more about her research? Checkout the following paper linked below. Islet-Expressed CXCL10 Promo...
Episode 22: Edward Phelps, PhD, Assistant Professor, University of Florida
October 08, 2020 21:08 - 45 minutes - 61.9 MBIn this episode, Edward Phelps joins Monica Westley to discuss the ongoing research in his laboratory at the University of Florida. Dr. Phelps’s research focuses on biomaterials engineering as a strategy for regenerative therapies with emphasis in the area of type 1 diabetes. The primary focus of the lab is the pancreatic islets of Langerhans and their diseases with an emphasis on beta cell dysfunction and autoimmunity in type 1 diabetes. To learn more about research at Phelps Laboratory cl...
Episode 21: Senta Georgia, PhD, Assistant Professor of Pediatrics, Keck School of Medicine of USC
October 05, 2020 23:19 - 41 minutes - 56.8 MBIn this episode, Senta Georgia joins Monica Westley to discuss her research at USC. Dr. Georgia's research involves the regeneration of insulin-producing, pancreatic beta cells as a potential therapeutic for patients with type 1 diabetes. Her research on how the enzyme, DNMT1, is critical to stem cells differentiating into pancreatic beta cells was featured on the cover of the journal Genes & Development. To learn more about Dr. Georgia's research and the ongoing research in her lab click o...
Episode 20: Peter Thompson, PhD, Assistant Professor, University of Manitoba
September 30, 2020 19:59 - 33 minutes - 46.1 MBIn this episode, Peter Thompson joins Monica Westley to discuss his research in the type 1 diabetes space. Dr. Thompson is an Assistant Professor at the University of Manitoba and his research focuses on investigating cellular and molecular mechanisms operating in pancreatic beta cells to understand how and why this disease occurs. Dr. Thompson- "There is some really exciting work coming out, particularly with relevance to the roll of the beta cell in type 1. In particular, it is really be...
Episode 19: Ekaterine Berishvili MD, PhD, Senior Scientist at University of Geneva
September 28, 2020 22:33 - 35 minutes - 48.5 MBIn this episode, Ekaterine Berishvili joins Monica Westley to discuss her research at the University of Geneva. Dr. Berishvili's research is currently focused on the bioengineering of vascularized and immune-protected bioartificial pancreas that can be transplanted into non-immunosuppressed patients. Interested in learning more about Dr. Berishvili's research? Clink on the link below for one of her recent publications. Immunomodulatory Properties of Amniotic Membrane Derivatives and Their ...
Episode 18: Kevin Otto, PhD, Professor at University of Florida
September 23, 2020 15:55 - 36 minutes - 49.8 MBIn this episode, Kevin Otto joins Monica Westley to discuss his research at The Neuroprostheses Research Lab at the University of Florida. Dr. Otto's research focuses on engineering neural interfaces for both research purposes as well as treatment options in neurological injuries or disease. Dr. Otto- "Eventual reinnervation can definitely lead to regeneration if the end target has a regeneration capability and so I think that there is a lot of intriguing harmony in that overall thinking. I...
Episode 17: Alejandro Caicedo, PhD, Professor of Medicine, University of Miami Miller School of Medicine
September 10, 2020 21:05 - 24 minutes - 33.6 MBIn this episode, Alejandro Caicedo joins Monica Westley to discuss his research in the type 1 diabetes space. Dr. Caicedo's research focuses on the biology of human islets and how the islets interact with the environment. Interested in learning more about Dr. Caicedo's research? Checkout the following published articles: 1) The Local Paracrine Actions of the Pancreatic α-Cell 2) Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signal...
Episode 16: Giuseppe Orlando, MD, PhD, Marie Curie Fellow, Associate Professor at the Wake Forest University School of Medicine
September 10, 2020 16:00 - 35 minutes - 48.6 MBIn this episode, Dr. Giuseppe Orlando joins Monica Westley to discuss his interest in type 1 diabetes and strategies for pancreas transplantation. Dr. Orlando is a kidney and pancreas transplant surgeon at the Wake Forest University School of Medicine. Dr. Orlando- "The problem of using the whole pancreas as a scaffold actually entails the same problems that full organ bioengineering puts us in front of. Which is that we can't replicate the vasculature of an organ. Research is shifting tow...
Episode 15: Antonio Citro, PhD, Project Leader of Pancreas by Engineering at the Diabetes Research Institute (DRI), Milan
September 04, 2020 17:05 - 26 minutes - 36.2 MBIn this episode, Antonio Citro joins Monica Westley to discuss his research at the Diabetes Research Institute in Milan, Italy. Dr. Citro provides insights to his journey as a researcher and what he is currently working on in the type 1 diabetes space. Dr. Citro- "I think a possible solution to protecting the newly implanted islet is gene editing or the modulation of the scaffold."
Episode 14: Giorgio Raimondi, PhD, Assistant Professor at Johns Hopkins University
September 03, 2020 16:00 - 45 minutes - 62.8 MBIn this episode, Giorgio Raimondi joins Monica Westley to discuss his research at Johns Hopkins University in the Vascularized and Composite Allotransplantation Laboratory. Dr. Raimondi provides insights to his recently published work titled: "Multiphase Assembly of Small Molecule Microcrystalline Peptide Hydrogel Allows Immunomodulatory Combination Therapy for Long‐Term Heart Transplant Survival." Dr. Raimondi- "I am a strong supporter of multidisciplinary approaches. The idea is to try to...
Episode 13: Dan Abebayehu, PhD, University of Virginia, The intersection between fibrosis and type 1 diabetes
September 01, 2020 16:00 - 16 minutes - 22.3 MBIn this episode, Dan Abebayehu joins Monica Westley to discuss his research in the matrix biology and engineering lab at University of Virginia. His work focuses on examining the role innate immunity plays in initiating fibrosis. Dr. Abebayehu- "Fibrosis emerges across multiple diseases and is often times one of the key obstacles to developing better therapies."
Episode 12: Bart Roep, PhD, Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes, Founding Chair of the department of Diabetes Immunology at City of Hope
August 28, 2020 22:43 - 37 minutes - 52.2 MBIn this episode, Bart Roep joins Monica Westley to discuss the current and future scientific work in the field of type 1 diabetes. Dr. Roep is the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and the founding chair of the Department of Diabetes Immunology within the Diabetes & Metabolism Research Institute at City of Hope. He serves as project director for The Wanek Family Project for type 1 diabetes at City of Hope, an ambitious initiative committed to developing a cure for type...
Episode 11: Jeffrey Millman, PhD, Assistant Professor at Washington University, Production of pancreatic insulin-producing β cells
August 27, 2020 17:07 - 36 minutes - 49.7 MBIn this episode, Jeffrey Millman joins Monica Westley to discuss his research. The major focus of the Millman laboratory is the in vitro production and study of pancreatic insulin-producing β cells from human pluripotent stem cells for use in cellular replacement therapy and drug screening. Dr. Millman- "The field right now is very hot and exciting! With the development and discovery of how to make insulin-producing β cells from stem cells that I and my colleagues developed when I was wo...
Episode 10: Paul-Peter Tak, Academic, business leader and biotech entrepreneur
August 26, 2020 16:00 - 44 minutes - 61.4 MBIn this episode, Paul-Peter Tak joins Monica Westley to discuss his innovative ideas within the type 1 diabetes space and how immunology can play a role in helping find a cure for T1D. Paul-Peter is an immunologist, academic, and venture partner who has specialized in the fields of rheumatology and immunology. Paul-Peter Tak- "I think the future is clearly in looking at type 1 diabetes in a different way. I would almost reclassify it (as an immunologist, not necessarily as a diabetes exper...
Episode 9: Izortze Santin Gomez, PhD, University of the Basque Country, Spain, icRNA and type 1 diabetes
August 25, 2020 16:00 - 19 minutes - 27 MBIn this episode, Izortze Santin joins Monica Westley to discuss her research in the type 1 diabetes space. Dr. Gomez is an associate professor at University of the Basque Country and a researcher at BioCruces Health Research Institute.
Episode 9: Izortze Santin Gomez, PhD, University of the Basque Country, Spain, icRNA and Type 1 Diabetes
August 25, 2020 16:00 - 19 minutes - 27 MBIn this episode, Izortze Santin joins Monica Westley to discuss her research in the Type 1 Diabetes space. Dr. Gomez is an associate professor at University of the Basque Country and a researcher at BioCruces Health Research Institute.
Episode 8: Ali Cinar, PhD, Director, Engineering center for diabetes research and education, Illinois institute of technology
August 24, 2020 16:00 - 40 minutes - 55.1 MBIn this episode, Ali Cinar joins Monica Westley to discuss his research and how he became interested in studying type 1 diabetes. Professor Cinar's research activities are concentrated in three areas: complex adaptive agent-based systems, modeling, simulation and control of biomedical systems, and supervision of manufacturing process operations.
Episode 7: Giovanni Amabile, PhD, CEO of Enthera, Developing first-in-class biologics for type 1 diabetes
August 23, 2020 23:50 - 29 minutes - 40.4 MBIn this episode, Giovanni Amabile joins Monica Westley to discuss the future of Enthera. Enthera is a biotech company building a pipeline of first-in-class biologics for several autoimmune conditions, with a focus in type 1 diabetes and inflammatory bowel disease.
Episode 7: Giovanni Amabile, PhD, CEO of Enthera, Developing first-in-class biologics for Type 1 Diabetes
August 23, 2020 23:50 - 29 minutes - 40.4 MBIn this episode, Giovanni Amabile joins Monica Westley to discuss the future of Enthera. Enthera is a biotech company building a pipeline of first-in-class biologics for several autoimmune conditions, with a focus in Type 1 Diabetes and Inflammatory Bowel Disease.
Episode 6: Jennifer Bridge, PhD, Bluestone Lab, Anderson Lab, UCSF
August 23, 2020 23:17 - 23 minutes - 32.2 MBIn this episode, Jennifer joins Nicole Phillips to discuss her research at UCSF in the Bluestone Lab and Anderson Lab. Jennifer's research focuses on understanding mechanisms regulating T-cell activation and studying an immunosuppressive population of T cells known as Tregs.
Episode 5: Rebecca Vaught, PhD, Co-Founder of Van Heron Labs, Reframing the understanding of organismal and cellular performance
August 23, 2020 21:50 - 16 minutes - 23.2 MBIn this episode, Rebecca Vaught joins Monica Westley to discuss her work at Van Heron Labs and its' potential intersection with type 1 diabetes. Van Heron Labs created a novel pipeline that uses genetic analysis to design a customized procedure for optimizing metabolism for a particular organism or cell, maximizing growth and product output.
Episode 4: Zoe Quandt, MD, Bluestone Lab, UCSF
August 23, 2020 21:14 - 18 minutes - 25.2 MBIn this episode, Zoe Quandt joins Nicole Phillips to discuss her research in the Bluestone Lab and Anderson Lab at UCSF. Zoe's research focuses on endocrine immune related adverse events following cancer immunotherapy.
Episode 3: Jonny White, PhD, Life with Type 1 Diabetes
August 23, 2020 19:51 - 43 minutes - 59.9 MBIn this episode, Jonny White joins Scott Phillips to discuss life with Type 1 Diabetes. Jonny is a media psychologist who has Type 1 Diabetes. He has been very influential and active in the T1D world since he was 15.
Episode 3: Jonny White, PhD, Life with type 1 diabetes
August 23, 2020 19:51 - 43 minutes - 59.9 MBIn this episode, Jonny White joins Scott Phillips to discuss life with Type 1 Diabetes. Jonny is a media psychologist who has type 1 diabetes. He has been very influential and active in the T1D world since he was 15.
Episode 2: Lane Desborough, Finessing blood sugar monitoring
August 22, 2020 01:05 - 47 minutes - 65.4 MBIn this episode, Lane Desborough joins Sajeev Saluja to discuss finessing blood sugar monitoring. Lane was the cheif engineer for insulin delivery at Medtronic and chief engineer at Bigfoot Biomedical. He is now pursuing a new idea in automated insulin delivery that is currently in stealth mode.
Episode 1: Nayara Leite, PhD, The Melton Lab, Harvard University
August 19, 2020 16:31 - 16 minutes - 22.6 MBIn this episode, Nayara Leite joins Nicole Phillips to discuss her research in The Melton Lab at Harvard University. Nayara's research focuses on using induced pluripotent stem cells for type 1 diabetes in vitro modeling and immunoprotection of beta cells.