TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes
283 episodes - English - Latest episode: 2 months ago -Welcome to TheSugarScience Podcast where our mission is to highlight and connect researchers in the type 1 diabetes space.
The(sugar)science is an interactive digital platform founded to curate the scientific conversation among type 1 diabetes (T1D) researchers. Our goal is to expedite a cure for T1D by promoting collaboration across diverse research disciplines.
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Episodes
Episode 69: Hans Sollinger, MD, PhD, Founder & Interim CSO of Endsulin
March 30, 2021 16:00 - 30 minutes - 41.9 MBIn this episode, we speak to Dr. Hans Sollinger, MD, PhD, Founder & Interim CSO of Endsulin. Dr. Sollinger has been a leader in diabetes care for decades and has revolutionized the field twice. Endsulin is overcoming the limitations of today's taxing diabetes treatments with a patented gene construct and simple process that re-engineers part of the liver, allowing it to produce and regulate insulin on its own. Learn more about Endsulin here!
Episode 68: Burcak Yesildag, PhD, Head of Islet Solutions at InSphero
March 25, 2021 16:00 - 21 minutes - 29 MBIn this episode, Burcak Yesildag joins us to discuss her work in the Islet Solutions Group at InSphero, generating advanced and high-throughput compatible assays and disease models for diabetes drug discovery. She also gives us some insight into a recent publication, "Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes". Full paper: Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes To learn more about InSphero: https://insphero.c...
Episode 67: Arun Sridhar, PhD, Co- Founder Skraps & Philippe Blancou, PhD, Professor at CNRS- Centre National de la Recherche Scientifique
March 23, 2021 16:00 - 50 minutes - 69 MBIn this episode, Arun Sridhar and Philippe Blancou join us to discuss their innovative work in the type 1 diabetes space. These researchers provide us details about one of their recent publications: Pancreatic nerve electrostimulation inhibits recent-onset autoimmune diabetes. Arun Sridhar is the host of Skraps, a top 10% rated scientific podcast. Tune in to listen to stories of scientific brilliance!
Episode 66: Ying Liu, PhD, and graduate students Paola Leon Plata and Maryam Zaroudi from University of Illinois at Chicago
March 18, 2021 16:00 - 31 minutes - 43.2 MBIn this episode, Dr. Ying Liu along with PhD students Paola Leon Plata and Maryam Zaroudi join us to talk about their recent publication, "Heterogeneous Toroidal Spiral Particles for Islet Encapsulation". Liu Laboratory at the University of Illinois Chicago Department of Chemical Engineering focuses on nano- and micro- materials to address current challenges in drug delivery and tissue engineering. Click here for the full paper, and here to learn more about Liu Laboratory.
Episode 64: Laia Gómez Muñoz, PhD student in Immunology, Germans Trias i Pujol Research Institute (IGTP)
March 16, 2021 16:00 - 24 minutes - 34.3 MBIn this episode, Laia Gómez Muñoz joins us to discuss her recent publication, NK Cell Subsets Changes in Partial Remission and Early Stages of Pediatric Type 1 Diabetes. Laia is a PhD student at the Immunology of Diabetes Group under the supervision of Dra. Marta Vives. Her research focuses on the identification of new biomarkers of partial remission in pediatric patients with autoimmune diabetes for their application in immunological monitoring and clinical trials.
Episode 65: Laia Gómez Muñoz, PhD student in Immunology, Germans Trias i Pujol Research Institute (IGTP)
March 16, 2021 16:00 - 24 minutes - 34.3 MBIn this episode, Laia Gómez Muñoz joins us to discuss her recent publication, NK Cell Subsets Changes in Partial Remission and Early Stages of Pediatric Type 1 Diabetes. Laia is a PhD student at the Immunology of Diabetes Group under the supervision of Dra. Marta Vives. Her research focuses on the identification of new biomarkers of partial remission in pediatric patients with autoimmune diabetes for their application in immunological monitoring and clinical trials.
Episode 64: Emily Sims, MD, Pediatric Endocrinologist and Assistant Professor of Pediatrics at Indiana University
March 11, 2021 17:00 - 17 minutes - 24.2 MBIn this episode, Dr. Emily Sims joins us to discuss her research focused on diabetes risk factors and treatments to predict or slow diabetes progression. Tune in to learn more about her recent publication on teplizumab, titled "Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals". Click here to read the full paper.
Episode 63: Alex Cogdill, PhD, Director of Business Development and Corporate Strategy at Immunai
March 09, 2021 17:00 - 29 minutes - 40 MBIn this episode, Alex Cogdill joins us to discuss Immunai. Immunai is an innovative biotech company that works with partners to discover and develop therapies through the integration of machine learning and single-cell multimodal omics at scale. Dr. Cogdill has 13 years of experience in drug discovery and research management; having published >50 scientific articles in the immuno-oncology space with >9,000 citations Learn more about Immunai here
Episode 62: Wendy Wolf, PhD, VP of Registry and Research at T1D Exchange
March 04, 2021 17:00 - 11 minutes - 16 MBIn this episode, Wendy Wolf joins us to talk about T1D Exchange and the work they are doing to improve T1D research. T1D Exchange strives to improve outcomes for the T1D population by driving real-world evidence and collaborative change. Their Registry is a long-term research study where individuals volunteer their data to contribute to research evidence. Learn more about T1D Exchange here, and the Registry here.
Episode 61: Peter Senior, PhD, Endocrinologist & Professor at University of Alberta and Kate Farnsworth, Patient Partner at Diabetes Action Canada
March 02, 2021 17:00 - 29 minutes - 40.8 MBIn this episode, Peter Senior and Kate Farnsworth join us to discuss the exciting work taking place at Diabetes Action Canada. Diabetes Action Canada recently launched Connect1d. This platform allows those living with T1D to contribute to research in areas that matter most to them, while also allowing researchers to engage with a diverse range of people living with T1D from across Canada. Interested in learning more about Connect1d? Visit their website.
Episode 60: José García-Tirado, PhD, Research Associate at the University of Virginia Center for Diabetes Technology
February 25, 2021 17:00 - 34 minutes - 47.7 MBIn this episode, Dr. José García-Tirado joins us to discuss his work with the individualization of behavior patterns (including eating and exercise patterns) from CGM, insulin pump, and activity tracker data. Click on the links below for some of his recent papers. Mapping data to virtual patients in type 1 diabetes Anticipation of Historical Exercise Patterns by a Novel Artificial Pancreas System Reduces Hypoglycemia During and After Moderate-Intensity Physical Activity in People with Ty...
Episode 59: Amelia Linnemann, PhD, Assistant Professor at Indiana University School of Medicine
February 23, 2021 17:00 - 34 minutes - 47.7 MBIn this episode, Amelia Linnemann joins us to speak about the mechanisms of adaptive stress response in the pancreatic islet. Dr. Linnemann provides us with some insight about a recent publication, Pancreatic beta cell autophagy is impaired in type 1 diabetes. Learn more about her work here
Episode 58: Qiufu Ma, PhD, Professor of Neurobiology at Harvard University, Dana-Farber Cancer Institute
February 16, 2021 17:00 - 39 minutes - 54.1 MBIn this episode, Qiufu Ma joins us to discuss the ongoing research taking place in his lab. Dr. Ma's lab focuses on two lines of research: mapping pain pathways and exploring how acupuncture works. Tune in to hear Dr. Ma discuss one of his recent publications, Somato-Autonomic Reflexes of Acupuncture. Learn more about Ma Lab here
Episode 57: Gaël McGill, PhD, Founder & CEO at Digizyme, Professor at Harvard Medical School
February 11, 2021 17:00 - 40 minutes - 55.1 MBIn this episode, Gaël McGill joins us to discuss ways in which cell and molecular visualization can inform the research and discovery process. Dr. McGill is the founder of Digizyme. Digizyme's mission is to innovate at the intersection of science, technology, art and learning to create accurate and effective visual context for understanding science. Follow the link below for an animation video that explains the fundamentals of SARS CoV-2 membrane binding. SARS CoV-2 animation To lea...
Episode 56: David Wraith, PhD, Professor of Immunology, Director of the Institute of Immunology and Immunotherapy, University of Birmingham
February 09, 2021 17:00 - 37 minutes - 51.2 MBIn this episode, David Wraith joins us to discuss his profound knowledge on autoimmunity and immunotherapy. His research team has revealed mechanisms whereby autoreactive T-cells escape deletion in the thymus and thus appear in the repertoire of all individuals. He also demonstrated that autoreactive T-cells can be silenced by suitable administration of fragments of their protein targets.
Episode 55: Jessica Gibson, MBA, CEO and Co-Founder of Ariel Precision Medicine
February 04, 2021 17:00 - 17 minutes - 23.6 MBIn this episode, Jessica Gibson joins us to discuss the latest work at Ariel Precision Medicine. Ariel is a health technology company seamlessly integrating complex genetics into clinical decision-making, empowering doctors and patients to prevent, mitigate or even reverse disease progression. Ariel's initial focus is pancreatic diseases including pancreatitis, diabetes and pancreatic cancer. Learn more about Ariel Precision Medicine here
Episode 54: Josh Nicholson, PhD, Co-Founder and CEO at Scite
February 02, 2021 17:00 - 44 minutes - 61.1 MBIn this episode, Josh Nicholson joins us to discuss how to use Scite. Scite is a deep learning platform that evaluates the reliability of scientific claims by citation analysis. Scite is a very valuable tool for all researchers. Smart citations for better research. Checkout scite here!
Episode 53: Bart Roep, PhD, Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes, Founding chair of the Department of Diabetes at City of Hope
January 28, 2021 17:00 - 32 minutes - 45.3 MBIn this episode, Bart Roep joins us to discuss the latest progress at City of Hope in the quest to cure type 1 diabetes. Early 2020 marked a milestone for science funded by The Wanek Project. Results had come in from a first-in-humans clinical trial testing a “reverse vaccine” for type 1 diabetes developed by Roep and his colleagues. The research showed the treatment to be safe and even indicated possible benefit as a therapy.
Episode 53: Bart Roep, PhD, Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes, Director, The Wanek Family Project for Type 1 Diabetes
January 28, 2021 17:00 - 32 minutes - 45.3 MBIn this episode, Bart Roep joins us to discuss the latest progress at City of Hope in the quest to cure type 1 diabetes. Early 2020 marked a milestone for science funded by The Wanek Family Project. Results had come in from a first-in-humans clinical trial testing a “reverse vaccine” for type 1 diabetes developed by Roep and his colleagues. The research showed the treatment to be safe and even indicated possible benefit as a therapy.
Episode 52: Scott Soleimanpour, MD, Associate Professor, Director of the Michigan Medicine Diabetes Transition Program, University of Michigan
January 26, 2021 17:00 - 42 minutes - 58.8 MBIn this episode, Scott Soleimanpour joins us to discuss his fascinating research taking place at the University of Michigan. Dr. Soleimanpour provides details about a recent publication, Mitophagy protects β cells from inflammatory damage in diabetes. Dr. Soleimanpour's lab focuses on the molecular and genetic regulation of the mitochondrial life cycle, with a focus on mitophagy, a pathway to dispose of unhealthy or damaged mitochondria. Our studies also concentrate on novel genetic target...
Episode 51: Darleen Sandoval, PhD, Professor at the University of Colorado
January 21, 2021 17:00 - 26 minutes - 36.9 MBIn this episode, Darleen Sandoval joins us to discuss her research and recent publication, Updating the Role of α-Cell Preproglucagon Products on GLP-1 Receptor–Mediated Insulin Secretion. Dr. Sandoval's current work utilizes basic research strategies to focus on two general themes of research. The first goal is to gain understanding on the role of a gastrointestinal peptide, GLP-1, in the gut-brain axis to regulate energy and glucose homeostasis. The second is to gain understanding on the ...
Episode 50: Ed Boyden, PhD, Y. Eva Tan Professor in Neurotechnology at MIT Howard Hughes Medical Institute
January 19, 2021 17:00 - 19 minutes - 26.8 MBIn this episode, Ed Boyden joins us to discuss his research at MIT and how an imaging technology developed by Boyden and his colleagues is applicable to type 1 diabetes researchers. Dr. Boyden leads the Synthetic Neurobiology Group, which develops tools for analyzing and repairing complex biological systems such as the brain, and applies them systematically to reveal ground truth principles of biological function as well as to repair these systems. He co-directs the MIT Center for Neurobiolo...
Episode 49: Dame Frances Ashcroft, PhD, Royal Society GlaxoSmithKline Research Professor at the University Laboratory of Physiology, Oxford
January 14, 2021 17:00 - 31 minutes - 43.1 MBIn this episode, Dame Frances Ashcroft joins us to discuss her research and recent publication titled, Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells. Dr. Frances Ashcroft's research focuses on ATP-sensitive potassium (KATP) channels and their role in insulin secretion, in both health and disease. To learn more about her research visit her website below. Ashcroft Group Photographer: Robert Taylor
Episode 49, Dame Frances Ashcroft, PhD, Royal Society GlaxoSmithKline Research Professor at the University Laboratory of Physiology, Oxford
January 14, 2021 17:00 - 31 minutes - 43.1 MBIn this episode, Dame Frances Ashcroft joins us to discuss her research and recent publication titled, Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells. Dr. Frances Ashcroft's research focuses on ATP-sensitive potassium (KATP) channels and their role in insulin secretion, in both health and disease. To learn more about her research visit her website below. Ashcroft Group Photographer: Robert Taylor
Episode 47: Teresa Rodriguez-Calvo, DVM, PhD, Junior Group Leader in the Type 1 Diabetes Pathology Research Unit, Institute of Diabetes Research, Helmholtz Zentrum München
January 12, 2021 17:15 - 27 minutes - 37.1 MBIn this episode, Teresa Rodriguez-Calvo joins us to discuss her type 1 diabetes research at the International Helmholtz Research School for Diabetes. Dr Rodriguez-Calvo is interested in the crosstalk between the immune system and the cells that produce insulin, called beta cells. We are working on identifying the cells that recognize different beta cell antigens and their exact localization in the pancreas, spleen, lymph nodes and duodenum, in order to better understand the pathogenesis of t...
Episode 48: Teresa Rodriguez-Calvo, DVM, PhD, Junior Group Leader in the Type 1 Diabetes Pathology Research Unit, Institute of Diabetes Research, Helmholtz Zentrum München
January 12, 2021 17:15 - 27 minutes - 37.1 MBIn this episode, Teresa Rodriguez-Calvo joins us to discuss her type 1 diabetes research at the International Helmholtz Research School for Diabetes. Dr Rodriguez-Calvo is interested in the crosstalk between the immune system and the cells that produce insulin, called beta cells. We are working on identifying the cells that recognize different beta cell antigens and their exact localization in the pancreas, spleen, lymph nodes and duodenum, in order to better understand the pathogenesis of t...
Episode 46: Susan Wong, PhD, Professor of Experimental Diabetes and Metabolism, Division of Infection and Immunity, Systems Immunity URI, Cardiff University, UK
January 07, 2021 19:37 - 38 minutes - 53 MBIn this episode, Susan Wong joins us to discuss her years of research experience working on the aetiology and pathogenesis of type 1 diabetes. Dr. Wong also discusses one of her recent publications, Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype. Follow the link below to read more about Dr. Wong's work: Dr. Wong's publications
Episode 47: Susan Wong, PhD, Professor of Experimental Diabetes and Metabolism, Division of Infection and Immunity, Systems Immunity URI, Cardiff University, UK
January 07, 2021 19:37 - 38 minutes - 53 MBIn this episode, Susan Wong joins us to discuss her years of research experience working on the aetiology and pathogenesis of type 1 diabetes. Dr. Wong also discusses one of her recent publications, Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype. Follow the link below to read more about Dr. Wong's work: Dr. Wong's publications
Episode 46: Francisco Leon, MD, PhD, Chief Scientific Officer & Co-Founder of Provention Bio
December 22, 2020 15:50 - 57 minutes - 79.1 MBIn this episode, Francisco Leon joins us to discuss how he became scientifically interested in type 1 diabetes and what led him to where he is today. Dr. Leon is the CSO and Co-Founder of Provention Bio. Provention Bio's mission is to change the world by unleashing the full potential of lives otherwise burdened of cut short by autoimmune disease. Provention Bio has an exciting pipeline of investigational candidates that aim to intercept type 1 diabetes by delaying or even preventing progre...
Episode 45: Yong Zhao, MD, PhD, President of Tianhe Stem Cell Biotechnologies Inc
December 17, 2020 15:50 - 32 minutes - 44.4 MBIn this episode, Yong Zhao joins us to discuss Tianhe Stem Cell Biotechnologies Inc. and the progress of clinical trials using the stem cell educator. Tianhe’s notable Stem Cell Educator Therapy was invented by Dr. Yong Zhao to effectively reverse the root causes of autoimmune diseases. Over the last 10 years, international multi-center clinical studies in the United States, China, and Spain have demonstrated the clinical safety and efficacy of Stem Cell Educator Therapy as it has been recog...
Episode 44: Julie Sneddon, PhD, Assistant Professor, UCSF School of Medicine
December 15, 2020 17:10 - 48 minutes - 67 MBIn this episode, Julie Sneddon joins us to discuss exciting type 1 diabetes research taking place in her lab. Dr. Sneddon’s laboratory studies the underlying biology of the cellular microenvironment, including the cellular diversity and lineage relationships of the non-epithelial compartment of the pancreas in the context of organogenesis, adult organ function, and disease. Recently, Dr. Sneddon was just awarded the Helmholtz Young Investigator in Diabetes (HeIDi) award. Visit Dr. Sneddon's...
Episode 43: Emrah Altindis, PhD, Assistant Professor, Boston College
December 14, 2020 20:02 - 45 minutes - 61.8 MBIn this episode, Emrah Altindis joins us to discuss his excellent publication, Parabacteroides distasonis insulin B:9-23 epitope mimic stimulates insulin specific T-cells and enhances type 1 diabetes in NOD mice. The main goal of Dr. Altindis' lab is to better understand the role of microbial mimicry mechanisms in human diseases and characterize these microbial proteins. In addition to the potential effects on metabolism and physiology of the host, these microbial mimickers have the potentia...
Episode 42: Roland Eils, PhD, Director for Digital Health at Berlin Institute of Health, and Luca Tosti, PhD, Postdoctoral Fellow at Berlin Institute of Health
December 10, 2020 15:45 - 39 minutes - 53.9 MBIn this episode, Roland Eils and Luca Tosti join us to discuss their research in the type 1 diabetes space. Scientists from the BIH are coordinating an international project on the single-cell analysis of the human pancreas. The project is part of a global project- known as the Human Cell Atlas. Dr. Eils and Dr. Tosti provide us with information about the Human Cell Atlas.
Episode 41: Per-Ola Carlsson, MD, PhD, Professor of Medical Cell Biology, Sr. Consultant in Endocrinology and Diabetology at Uppsala Hospital
December 08, 2020 15:30 - 44 minutes - 60.9 MBIn this episode, Per-Ola Carlsson joins us to discuss his latest research. Dr. Carlsson's work focuses on developing means to intervene with the development of type 1 diabetes mellitus and find treatment strategies to restore glucose homeostasis in patients with type 1 using cell therapy. Want to read more about his work? Checkout a recent publication, Better HbA1c during the first years after diagnosis of type 1 diabetes is associated with residual C peptide 10 years later
Episode 40: Reena Singh, PhD, Research Fellow at The University of Sydney, Australia
December 03, 2020 15:45 - 32 minutes - 44.5 MBIn this episode, Reena Singh joins us to discuss her research and one of her recent publications titled, Enhanced Structure and Function of Stem Cell-Derived Beta-Like Cells Cultured on Extracellular Matrix. Dr. Singh is a developmental and stem cell biologist and her current area of research is to develop cell replacement therapy for people living with type 1 diabetes. Dr. Singh is working towards understanding the effect of beta cell niche on its structure and function and modifying the mi...
Episode 40: Reena Singh, MD, PhD, Research Fellow at The University of Sydney, Australia
December 03, 2020 15:45 - 32 minutes - 44.5 MBIn this episode, Reena Singh joins us to discuss her research and one of her recent publications titled, Enhanced Structure and Function of Stem Cell-Derived Beta-Like Cells Cultured on Extracellular Matrix. Dr. Singh is a developmental and stem cell biologist and her current area of research is to develop cell replacement therapy for people living with type 1 diabetes. Dr. Singh is working towards understanding the effect of beta cell niche on its structure and function and modifying the mi...
Episode 39: vLUME, 3D Nanoimaging Platform, Alex Kitching, Alex Spark, Steven F. Lee, PhD
December 01, 2020 15:45 - 26 minutes - 36.4 MBIn this episode, Alex Kitching, Alex Spark, and Steven Lee join us to discuss vLUME technology, 3D Nanoimaging Platform and how it is applicable to type 1 diabetes researchers. vLUME is the world's first and only Virtual Reality solution for Super-resolution Microscopy. Visualise, segment, and analyse in real-time your massive localization data at any scale. Click the following link for a live demo of the technology: Live Demo- Helper T Cell
Episode 38: Jacob Hecksher-Sørensen, Principal Scientist at Gubra, Imaging Diabetes Using Light Sheet Microscopy
November 30, 2020 15:45 - 9 minutes - 13.7 MBIn this episode, Jacob Hecksher-Sørensen joins us to discuss imaging diabetes using light sheet microscopy. Jacob walks us through some of the advantages of using this technology and provides us with a live demonstration from two previous experiments. Checkout the full live demonstration following the link below: https://youtu.be/TmbXq5F_41w Want to learn more about his published work? Follow the link below: 3D quantification of changes in pancreatic islets in mouse models of diabetes t...
Episode 37: Madina Makhmutova, PhD, Postdoctoral Research Associate at University of Miami, Miller School of Medicine
November 19, 2020 16:53 - 34 minutes - 47.6 MBIn this episode, Madina Makhmutova joins us to discuss her recent publication, Pancreatic beta cells communicate with vagal sensory neurons. Her research findings may have important implications for type 1 diabetes researchers. To learn more about Dr. Makhmutova's research in the Islet-Caicedo Lab follow the link below: Islet-Caicedo Lab
Episode 36: Andrew Sas, MD, PhD, Assistant Professor at Ohio State University Wexner Medical Center
November 17, 2020 15:45 - 24 minutes - 34.2 MBIn this episode, Andrew Sas joins us to discus his recent publication, A new neutrophil subset promotes CNS neuron survival and axon regeneration. Dr. Sas also discusses ongoing research in his lab and how the neutrophil may have the potential to mediate inflammation in other areas of the body, such as the pancreatic beta call under autoimmune attack in type 1 diabetes. Listen to this episode to gain new insight and help address some important questions that were brought up and need further...
Episode 36: vLUME, 3D Nanoimaging Platform- Alex Kitching, Alex Spark, Steven F. Lee, PhD
November 10, 2020 16:11 - 26 minutes - 36.4 MBIn this episode, Alex Kitching, Alex Spark, and Steven Lee join Monica Westley to discuss vLUME technology, 3D Nanoimaging Platform, and how it is applicable to type 1 diabetes researchers. vLUME is the world's first and only Virtual Reality solution for Super-resolution Microscopy. Visualise, segment and analyse in real-time your massive localization data at any scale. Click the following link for a live demo of the technology: Live Demo- Helper T Cell
Episode 35: Calvin Carter, PhD, Sunny Huang, MD/PhD Candidate, Co-Founders of Geminii Health
November 09, 2020 22:54 - 29 minutes - 40.2 MBIn this episode, Calvin Carter and Sunny Huang join Monica Westley to discuss their new findings published Oct. 6 in Cell Metabolism, Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes, and new venture Geminii Health. Geminii Health is a medical device company that is pioneering a new wave of medicines and are building the NuWave, a wearable remote control to manage blood sugar. Listen in as Dr. Carter and Dr. Huang discuss the pure serendipity of their findings. Want ...
Episode 35: Calvin Carter, PhD, Sunny Huang, MD/PhD candidate, Co-Founders of Geminii Health
November 09, 2020 22:54 - 29 minutes - 40.2 MBIn this episode, Calvin Carter and Sunny Huang join Monica Westley to discuss their new findings published Oct. 6 in Cell Metabolism, Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes, and new venture Geminii Health. Geminii Health is a medical device company that is pioneering a new wave of medicines and are building the NuWave, a wearable remote control to manage blood sugar. Listen in as Dr. Carter and Dr. Huang discuss the pure serendipity of their findings. Want ...
Episode 35: Calvin Carter, PhD, Sunny Huang, MD, PhD, Co-Founders of Geminii Health
November 09, 2020 22:54 - 29 minutes - 40.2 MBIn this episode, Calvin Carter and Sunny Huang join Monica Westley to discuss their new findings published Oct. 6 in Cell Metabolism, Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes, and new venture Geminii Health. Geminii Health is a medical device company that is pioneering a new wave of medicines and are building the NuWave, a wearable remote control to manage blood sugar. Listen in as Dr. Carter and Dr. Huang discuss the pure serendipity of their findings. Want ...
Episode 34: Avnesh Thakor, MD, PhD, Assistant Professor of Radiology at Stanford University Medical Center
November 06, 2020 20:11 - 31 minutes - 43.9 MBIn this episode, Avnesh Thakor joins Sajeev Saluja to discuss bioscaffolds that are used to support pancreatic islet transplantation. Dr. Thakor's research interests are focused primarily on the pancreas, with respect to regenerative medicine and oncology. In Thakor's lab they are creating biocompatible 3D structures which contain spaces to accommodate islets. These bioscaffolds will aim to facilitate oxygen generation and angiogenesis, both of which are essential for islet survival and func...
Episode 33: Tiffany Richardson, PhD candidate, Vanderbilt University School of Medicine
November 04, 2020 16:00 - 21 minutes - 30.1 MBIn this episode, Tiffany Richardson joins Monica Westley to discuss her ongoing research in the Powers-Brissova Research Group. Richardson's research focuses on elucidating the innervation landscape within the exocrine and endocrine portions of the pancreas. Want to read more about Richardson's work? Follow the links below. Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration 2140-P: Pancreatic Islet and Exocrine Tiss...
Episode 32: Alexandra Smink, PhD, University Medical Center Groningen (UMCG)
November 02, 2020 16:00 - 28 minutes - 39.4 MBIn this episode, Alexandra Smink joins Monica Westley to discuss her research in the type 1 diabetes space. Dr. Smink's research focuses on polymer scaffolds for pancreatic islet transplantation. In 2018, Dr. Smink was awarded the young investigator JDRF award and most recently was awarded the EASD Rising Star Award. Using so-called extracellular matrix, which can be used to wrap the islets up and, thus, protect them from the outside world where the immune system lurks, Dr Smink from the Ne...
Episode 31: Patrick MacDonald, PhD, & Jasmine Maghera, University of Alberta
October 30, 2020 16:00 - 26 minutes - 36.7 MBIn this episode, Patrick MacDonald and Jasmine Maghera join Monica Westley to discuss the ongoing research in Dr. Patrick's laboratory. Some exciting new directions in the laboratory include islet-cell phenotyping by combined patch-clamp and single-cell sequencing; and computational modelling of human islet cell profiles. To learn more about MacDonald Islet Biology Laboratory, click the link below. MacDonald Islet Biology Laboratory
Episode 30: Lonnie Shea, PhD, William and Valerie Hall Chair, Biomedical Engineering Steven A. Goldstein Collegiate Professor at University of Michigan
October 28, 2020 16:00 - 32 minutes - 45.1 MBIn this episode, Lonnie Shea joins Monica Westley to discuss the intersection of regenerative medicine, immune engineering, precision health and type 1 diabetes. Dr. Shea's projects include islet transplantation for diabetes therapy and nerve regeneration for treating paralysis. To learn more about the ongoing research taking place at The Shea Lab, click on the link below. The Shea Lab
Episode 29: Adam Ramzy, MD/PhD Candidate at the University of British Columbia
October 27, 2020 16:00 - 29 minutes - 40.3 MBIn this episode, Adam Ramzy joins Monica Westley to discuss his recent publication, Revisiting proinsulin processing: evidence that human β-cells process proinsulin with prohormone convertase (PC) 1/3 but not PC2. Adam's research projects include investigating prohormone processing and developing gene and cell based therapies for diabetes in the lab of Dr. Timothy Kieffer. To learn more about The Kieffer Lab, click on the link below. The Kieffer Lab