TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes artwork

TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes

283 episodes - English - Latest episode: 2 months ago -

Welcome to TheSugarScience Podcast where our mission is to highlight and connect researchers in the type 1 diabetes space.

The(sugar)science is an interactive digital platform founded to curate the scientific conversation among type 1 diabetes (T1D) researchers. Our goal is to expedite a cure for T1D by promoting collaboration across diverse research disciplines.

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Episodes

Episode 112: Karsten Buschard, MD, and Kristina Pedersen, PhD, Rigshospitalet, Denmark

January 12, 2022 02:13 - 36 minutes - 49.8 MB

In this episode, Dr. Buschard and Dr. Pedersen join us to discuss dysregulation of the innate antiviral immune system in type 1 diabetes. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 111: Maria Jose Redondo, MD, PhD, Baylor University

January 07, 2022 03:50 - 31 minutes - 43 MB

In this episode, Dr. Maria Jose Redondo joins us to discuss what's new with TCG7L2 and insulin sensitivity. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 110: Ron Weiss, PhD, MIT

January 05, 2022 06:04 - 36 minutes - 50.2 MB

In this episode, Dr. Ron Weiss joins us to discuss an engineered protein-phosphorylation toggle network with implications for endogenous network discovery. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 109: Jessica Weaver, PhD, ASU

December 17, 2021 05:51 - 48 minutes - 66.9 MB

In this episode, Dr. Jessica Weaver joins us to discuss eliminating immune suppression in cell therapies to treat type 1 diabetes. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 108: Mark Huising, PhD, UC Davis

December 15, 2021 05:07 - 36 minutes - 50.8 MB

In this episode, Dr. Mark Huising joins us to discuss observing islet cell behavior in real time. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 107: Patricia Aparicio-Domingo, PhD, ABcam

December 10, 2021 23:57 - 37 minutes - 51.6 MB

In this episode, Dr. Patricia Aparicio-Domingo joins us to discuss what's new at ABcam, a leading supplier of protein research tools. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 106: Milena Pavlovic and Lenneke Schieffer, ImmuneML

December 09, 2021 06:40 - 26 minutes - 36.1 MB

In this episode, Dr. Milena Pavlovic and Dr. Lenneke Schieffer join us to discuss Immune ML, an "open-source ecosystem for machine learning analysis of adaptive immune receptor repertoires. Immune ML Website: https://immuneml.uio.no/ Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 106: Milena Pavlovic and Lonneke Scheffer, ImmuneML

December 09, 2021 06:40 - 26 minutes - 36.1 MB

In this episode, Milena Pavlovic and Lonneke Scheffer join us to discuss ImmuneML, an "open-source ecosystem for machine learning analysis of adaptive immune receptor repertoires". ImmuneML Website: https://immuneml.uio.no/ Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 105: Jennifer Wang, MD, UMass and Decio L. Eizirik, MD, PhD, ULB

December 03, 2021 05:35 - 56 minutes - 76.9 MB

In this episode, Dr. Jennifer Wang and Dr. Decio Eizirik join us to discuss T1 interferons and autoimmune diseases.  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 104: Dario Gerace, PhD, Harvard

December 01, 2021 05:29 - 28 minutes - 39.8 MB

In this episode, Dr. Dario Gerace joins us to discuss engineering immune-evasive stem cell-derived islet cells. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 103: Austin Lefebvre, PhD, UCI

November 23, 2021 18:55 - 18 minutes - 25.5 MB

In this episode, Dr. Austin Lefebvre joins us to discuss mitochondrial causes and consequences in diabetes. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 102: Ana Conesa, PhD, UF

November 19, 2021 06:44 - 29 minutes - 40.7 MB

In this episode, Dr. Ana Conesa joins us to discuss multi-OMICs modeling of T1D linking lipid impairment with T1D onset. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/  

Episode 101: Haiting Ma, PhD, MIT

November 17, 2021 01:25 - 29 minutes - 40.5 MB

In this episode, Dr. Haiting Ma joins us to discuss a synthetic immune system and how it implicates beta-cell pyroptosis during T-cell mediated autoimmunity. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 100: Cassie Robertson, PhD, UVA

November 11, 2021 18:50 - 50 minutes - 69.2 MB

In this episode, Dr. Cassie Robertson joins us to discuss the discovery and characterization of genetic susceptibility loci in T1D.    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 99: Decio L. Eizirik, MD, PhD, ULB

November 09, 2021 20:00 - 58 minutes - 79.9 MB

In this episode, Dr. Decio Eizirik joins us to discuss the misguided dialog between beta cells and the immune system in T1D.   Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 98: Yasmin Mohseni, PhD, King‘s College London

November 05, 2021 05:27 - 26 minutes - 36.6 MB

In this episode, Dr. Yasmin Mohseni joins us to discuss CAR-Treg therapy and immunomodulation.    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 97: Michele Solimena, MD, PhD, TU Dresden

November 02, 2021 23:56 - 30 minutes - 41.9 MB

In this episode, Dr. Michele Solimena joins us for a deep dive into beta-cell biology.    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 96: Jeff Bluestone, PhD

October 21, 2021 19:39 - 32 minutes - 44.4 MB

Dr. Jeff Bluestone and others join us to discuss Tregs and Sonoma Bio.    This episode is in Ask the Expert style   Ask the Expert is a 30 minute digital cafe experience where scientists and grad students can meet up and exchange with thought leaders in the field of type one diabetes.    Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/ 

Episode 95: Roberto Mallone, MD, PhD, INSERM FR

September 12, 2021 18:59 - 31 minutes - 43.4 MB

Dr. Robert Mallone joins us to discuss T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: Reprogramming Tregs and other whole cell tweaks.   This episode is in Ask the Expert style   Ask the Expert is a 30 minute digital cafe experience where scientists and grad students can meet up and exchange with thought leaders in the field of type one diabetes.    Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/ 

Episode 94: Zach Freyberg, MD, PhD, UPITT

August 26, 2021 14:28 - 39 minutes - 54.2 MB

Dr. Zach Freyberg joins us to discuss new roles for dopamine as a pancreatic modulator of insulin and glucagon secretion.   This episode is in Ask the Expert style...   Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet up and exchange with thought leaders in the field of type one diabetes.    Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/ 

Episode 93: Graciela Lorca, PhD, UFLA

August 19, 2021 13:33 - 26 minutes - 36.3 MB

Dr. Graciela Lorca joins us to discuss microbiome probiotics & T1D   This episode is in Ask the Expert style   Ask the Expert is a 30 minute digital cafe experience where scientists and grad students can meet up and exchange with thought leaders in the field of type one diabetes.    Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/ 

Episode 92: Megan Penno, PhD, ENDIA

August 17, 2021 22:39 - 43 minutes - 60 MB

Dr. Megan Penno joins us to discuss environmental determinants of islet autoimmunity.   This episode is in Ask the Expert format.   Ask the Expert is a 30 minute digital cafe experience where scientists and grad students can meet up and exchange with thought leaders in the field of type one diabetes.    Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert

Episode 91: Maike Sander, MD, UCSD

August 11, 2021 16:00 - 31 minutes - 43.9 MB

Dr. Maike Sander joins us to discuss building human stem cell models to study beta cell demise in T1D.    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!  https://thesugarscience.org/ask-the-expert/

Ask the Expert: Kyle Gaulton, PhD, UCSD

July 30, 2021 16:00 - 48 minutes - 66 MB

Dr. Kyle Gaulton joins us to discuss interpreting type 1 diabetes risk with genetics and single cell epigenetics.    This episode is in our Ask the Expert format. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!  https://thesugarscience.org/ask-the-expert/

Episode 90: Kyle Gaulton, PhD, UCSD

July 30, 2021 16:00 - 48 minutes - 66 MB

Dr. Kyle Gaulton joins us to discuss interpreting type 1 diabetes risk with genetics and single cell epigenetics.    This episode is in our Ask the Expert format. Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!  https://thesugarscience.org/ask-the-expert/

Ask the Expert: Victoria Salem PhD, Imperial College London

July 28, 2021 16:00 - 33 minutes - 45.6 MB

Dr. Victoria Salem joins us to discuss in-vivo evidence for islet "hub cells".    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 89: Victoria Salem PhD, Imperial College London

July 28, 2021 16:00 - 33 minutes - 45.6 MB

Dr. Victoria Salem joins us to discuss in-vivo evidence for islet "hub cells".    Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!   https://thesugarscience.org/ask-the-expert/

Episode 88: Milena Pavlovic and Lonneke Scheffer, ImmuneML

July 23, 2021 16:00 - 27 minutes - 37.6 MB

Milena Pavlovic and Lenneke Schieffer join us to discuss Immune ML, an "open-source ecosystem for machine learning analysis of adaptive immune receptor repertoires.    ImmuneML website: https://immuneml.uio.no/   Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!    https://thesugarscience.org/ask-the-expert/ 

Ask the Expert: Milena Pavlovic, PhD, and Lenneke Schieffer, PhD, ImmuneML

July 23, 2021 16:00 - 27 minutes - 37.6 MB

Dr. Milena Pavlovic and Dr. Lenneke Schieffer join us to discuss Immune ML, an "open-source ecosystem for machine learning analysis of adaptive immune receptor repertoires.    ImmuneML website: https://immuneml.uio.no/   Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!    https://thesugarscience.org/ask-the-expert/ 

Episode 88: Milena Pavlovic, PhD, and Lenneke Schieffer, PhD, ImmuneML

July 23, 2021 16:00 - 27 minutes - 37.6 MB

Dr. Milena Pavlovic and Dr. Lenneke Schieffer join us to discuss Immune ML, an "open-source ecosystem for machine learning analysis of adaptive immune receptor repertoires.    ImmuneML website: https://immuneml.uio.no/   Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!    https://thesugarscience.org/ask-the-expert/ 

Episode 87: Braden Tierney, PhD, Harvard University

July 21, 2021 16:00 - 29 minutes - 40.8 MB

Dr. Braden Tierney joins us to discuss gene-level metagenomic architectures across diseases that yield high-resolution microbiome diagnostic indicators.    This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 86: Ask the Expert Carmen Valcarce PhD and Klara Klein MD PhD

July 14, 2021 16:00 - 1 hour - 21.7 MB

In this Ask the Expert podcast we talk with Carmen Valcarce PhD and Klara Klein MD PhD from VTV Therapteutics. We discuss TTP399 development as an adjunct therapy to insulin in patients with Type 1 Diabetes. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org...

Episode 86: Carmen Valcarce PhD and Klara Klein MD PhD

July 14, 2021 16:00 - 1 hour - 21.7 MB

In this Ask the Expert podcast we talk with Carmen Valcarce PhD and Klara Klein MD PhD from VTV Therapteutics. We discuss TTP399 development as an adjunct therapy to insulin in patients with Type 1 Diabetes. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org...

Episode 85: SOS #4-What are the most promising approaches for beta cell replacement moving forward?

July 13, 2021 16:00 - 1 hour - 44.1 MB

Topic: What are the most promising approaches for beta cell replacement moving forward? Anchors: Doug Melton PhD (HSCI), Ali Naji MD PhD (PENN), Mike Rickles MD (PENN), Felicia Pagliuca PhD (Vertex) Matthias Hebrok PhD, (UCSF) Panel: Jon Odorico MD (U Wisc), Pete Butler MD (UCLA) Cherie Stabler, PhD (UF), Mark Atkinson, PhD (UF), Ekaterine Bershivili MD PhD (UGeneva) WHAT: State of the Science is an interactive conversation with room for granular and lively debate focused on the most p...

Episode 84: Jessica Kenison, PhD, Brigham and Women's Hospital

July 10, 2021 16:00 - 33 minutes - 21.7 MB

Dr. Jessica Kenison joins us to discuss re-balancing the immune system and introducing antigen-specific immune tolerance to treat T1D. Dr. Jessica Kennison is a Postdoctoral Research Fellow at Brigham and Women's Hospital and Scientist at AnTolRx, Inc. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a ...

Episode 84: Ask the Expert: Jessica Kenison, PhD, Brigham and Women's Hospital

July 10, 2021 16:00 - 33 minutes - 21.7 MB

Dr. Jessica Kenison joins us to discuss re-balancing the immune system and introducing antigen-specific immune tolerance to treat T1D. Dr. Jessica Kennison is a Postdoctoral Research Fellow at Brigham and Women's Hospital and Scientist at AnTolRx, Inc. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a ...

Episode 83: Teresa Mastracci, PhD, Indiana University

June 10, 2021 16:00 - 32 minutes - 45.1 MB

In this episode, Dr. Teresa Mastracci joins us to discuss the exocrine pancreas in T1D; is it a player, or merely a spectator?  Dr. Mastracci is an Assistant Professor in Biology at Indiana University. In 2017 she was named one of the top Ten Under 40 up & coming stars in Biopharma Research and Business by Genetic Engineering News and was recognized as one of the Indianapolis Business Journal’s Forty Under 40. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute di...

Episode 82: Elliot Botvinick, PhD, UCI

June 03, 2021 16:00 - 28 minutes - 38.8 MB

In this episode, Dr. Elliot Botvinick joins us to talk about his work with multi-analyte sensing and insulin infusion at UCI. Tune in to hear about iGLOBE.  This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 81: Andrew Wang, MD, Kin Man Au, PhD, Roland Tisch, PhD, University of North CarolinaW

May 27, 2021 16:00 - 29 minutes - 40.5 MB

In this episode, Dr. Andrew Wang, Dr. Kin Man Au, and Dr. Roland Tisch from the University of North Carolina join us to discuss their recent work, including the recent publication, "Immune Checkpoint-Bioengineered Beta Cell Vaccine Reverses Early-Onset Type 1 Diabetes".    Full paper link: https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202101253   This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad student...

Episode 80: Jonathan Weissman, PhD, Professor of Biology at MIT

May 13, 2021 16:00 - 26 minutes - 36.6 MB

In this episode, Dr. Jonathan Weissman joins us in our Ask the Expert format to discuss genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.  This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 79: Rob Screaton, PhD, Associate Professor at The University of Toronto

May 11, 2021 05:59 - 38 minutes - 53.2 MB

In this episode, Rob Screaton joins us to discuss one major question: Can we get adult human beta cells to regenerate? His lab uses high-throughput functional genomic imaging screens to identify novel players involved in cell signaling pathways that control human pancreatic beta cell proliferation. In addition, we are interested in the function and quality control of mitochondria, critical subcellular organelles essential for cell function and survival. This episode is in our Ask the Exper...

Episode 78: Avenesh Thakor, MD, PhD, Assistant Professor of Radiology at Stanford University (Re-Release)

May 04, 2021 17:39 - 31 minutes - 43.9 MB

In this episode re-release, Avnesh Thakor joins us to discuss bioscaffolds that are used to support pancreatic islet transplantation. Dr. Thakor's research interests are focused primarily on the pancreas, with respect to regenerative medicine and oncology. In Thakor's lab, they are creating biocompatible 3D structures which contain spaces to accommodate islets. These bioscaffolds will aim to facilitate oxygen generation and angiogenesis, both of which are essential for islet survival and fun...

Episode 77: Matthias Barth, PhD, Leuphana University of Lüneburg in Germany

April 29, 2021 16:00 - 20 minutes - 27.5 MB

In this episode, Professor Matthias Barth joins us to discuss his work studying higher education at Leuphana University in Germany. Dr. Barth is one of the steering-group members of the Postdoc Academy for Transformational Leadership, a training programme for researchers in the sustainability field. 

Episode 76: David Wagner, PhD, University of Colorado

April 22, 2021 16:00 - 47 minutes - 65.6 MB

In this episode, David Wagner joins us to present and answer questions on his work at the University of Colorado and with Op-T-Mune. This episode is in our Ask the Expert style:  Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe! https://thesugarscience.org/ask-the-expert/

Episode 75: Eiji Yoshihara, PhD, Principal Investigator, The Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center

April 20, 2021 16:12 - 29 minutes - 40.1 MB

In this episode, Eiji Yoshihara joins us to discuss the research taking place at Yoshihara Lab at the Lundquist Institute. The overarching goal of the Yoshihara Lab is to understand the origins of life and physiology through utilizing state-of-the-art biomedical technologies. Japanese Translation @ minute 25 Learn more about the Yoshihara Lab Here

Episode 74: Toby Coates, PhD, Professor of Medicine at the University of Adelaide

April 15, 2021 16:00 - 22 minutes - 31.2 MB

In this episode, Dr. Toby Coates joins us to give us some insights into his work with the Biodegradable Temporizing Matrix (BTM). 

Episode 73: Matthieu Raoux, PhD, HDR, Associate Professor, University of Bordeaux, France

April 13, 2021 16:00 - 42 minutes - 58.1 MB

In this episode, Matthieu Raoux joins us to talk about his fascinating research at the University of Bordeaux, France. Dr. Raoux provides insights to his recent publication: Dynamic Uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets. " Our data provide a new uni- and multicellular model of islet β-cell activation: during the 1st phase, small but highly active β-cell clusters are dominant, whereas during the 2nd phase electrical coupling generates large functional ...

Episode 72: Noel G. Morgan, PhD, Professor of Endocrine Pharmacology and Director of the Institute of Biomedical & Clinical Science at the University of Exeter

April 08, 2021 16:00 - 42 minutes - 58.4 MB

In this episode, Professor Noel G. Morgan joins us to discuss his work in cellular pharmacology and studying the pathophysiology of pancreatic beta-cells in diabetes. He also talks about his work with B cells and a recent publication, "Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to “B” or Not to “B”: Is That Still the Question?".  Link to his paper: https://www.frontiersin.org/articles/10.3389/fendo.2021.617437/full

Episode 71: Alok Joglekar, PhD, Assistant Professor at University of Pittsburgh School of Medicine

April 06, 2021 15:31 - 21 minutes - 29.8 MB

In this episode, we speak with Alok Joglekar about his fantastic research at the University of Pittsburg. Dr. Joglekar provides us with some insights to his publication: T cell antigen discovery. T cells play a critical role in the elimination of pathogens and the surveillance of pathological cells.   Read the full text here

Episode 70: Matthias von Herrath, MD, Professor at the La Jolla Institute for Immunology and Vice President and Senior Medical Officer at Novo Nordisk

April 01, 2021 16:00 - 36 minutes - 49.8 MB

In this episode, Dr. Matthias von Herrath joins us to discuss his work at the La Jolla Institute for Immunology and at pharmaceutical company Novo Nordisk. He discusses one of his recently published papers, "Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial".  Full paper link: https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00019-X/...

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