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Plenary Session

387 episodes - English - Latest episode: 4 days ago - ★★★★★ - 722 ratings

A podcast on medicine, oncology, & health policy.
Host: Vinay Prasad, MD MPH from University of California San Francisco.
Tweet your feedback to @Plenary_Session or e-mail [email protected]

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Episodes

3.08 Racial Concordance in Birthing Mortality & HERO for Journal Club with Fellow Dr. Michael Burns

August 22, 2020 03:01 - 1 hour - 90.7 MB

This week we take a deep dive into two recently published studies, their surrounding controversy, and the broader implications. The first study was published in the journal Proceedings of the National Academy of Sciences of the USA and is titled "Physician–patient racial concordance and disparities in birthing mortality for newborns". The second was published in the New England Journal of Medicine and is titled "Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer", com...

3.07 Lung Cancer Omics and Mortality, PPIs and COVID-19, & RECIST with Dr. Elizabeth Eisenhauer

August 15, 2020 00:53 - 2 hours - 148 MB

We have a lot in store for you this week! We start off by evaluating two recently published studies: "Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer" (published in the Journal of Clinical Oncology: Oncology Practice) and "The Effect of Advances in Lung-Cancer Treatment on Population Mortality" (published in the New England Journal of Medicine). We talk a bit about tracking down the validity of a reference. We sit down with Dr. Branden Tarlow to discuss his tho...

3.06 COVID-19 Vaccine Access, ADAURA, QOTW, & Journal Club with Fellow Dr. Karine Tawagi

August 07, 2020 22:31 - 1 hour - 108 MB

We start this week's episode by discussing access to investigational COVID-19 vaccines and recapping the problems with the ADAURA study. We transition from there to a Question of the Week with medical student Audrey Tran of Oregon Health & Science University. Finally, we introduce a new segment - Journal Club with a Fellow. In this inaugural segment we invite Dr. Karine Tawagi of the Oschner Clinic in Louisiana to the podcast to talk about IMbrave150. IMbrave150: doi.org/10.1056/NEJMoa19157...

3.05 LIVE! A Midsummer Night's Stream

July 30, 2020 22:41 - 1 hour - 72.8 MB

This is the recording of a LIVE episode of Plenary Session in which Dr. Sue S Yom interviewed our host, Dr. Vinay Prasad, on how he built his career and how he conceptualizes his work. There's also a surprise guest near the end! Thank you to Dr. Kaleigh Doke, Dr. Brian Kavanagh, and the Virtual Visiting Professor Network for hosting this special episode. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

3.04 Listener Questions & MedTwitter and Risk-Benefit Profile of Ramucirumab with Dr. Bishal Gyawali

July 24, 2020 21:36 - 1 hour - 87 MB

This week we respond to several questions sent in by listeners and then we interview Dr. Bishal Gyawali of Queen's University in Kingston, Ontario, Canada on MedTwitter, other recent events, and his recently published paper titled "Assessing the risk-benefit profile of ramucirumab in patients with advanced solid tumors: A meta-analysis of randomized controlled trials". Ramucirumab: doi.org/10.1016/j.eclinm.2020.100458 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube...

3.03 The National Lung Matrix Trial & the Major Flaw of the SPRINT Trial with Dr. Mark Friedberg

July 18, 2020 01:08 - 1 hour - 68 MB

This week we discuss two major papers: The first was just recently released in Nature and it's titled "The National Lung Matrix Trial of personalized therapy in lung cancer". The second is a few years old, but exemplifies the importance of trial design. We discuss the second paper, titled "A Randomized Trial of Intensive versus Standard Blood-Pressure Control" and published in the New England Journal of Medicine with Dr. Mark Friedberg, a health policies and performance measurement researcher...

3.02 BONUS! National Clinician Scholars Program with Dr. Hilary Seligman

July 13, 2020 23:57 - 34 minutes - 32.7 MB

This week's BONUS episode is a discussion of the National Clinician Scholars Program with Dr. Hilary Seligman, the head of the program at University of California, San Francisco. The deadline for the application for the 2021-2023 cohort is July 15, 2020 (very soon!), though there may be some leniency due to the pandemic. National Clinician Scholars Program: https://nationalcsp.org/ UCSF National Clinician Scholars Program: https://nationalscholars.ucsf.edu/ Back us on Patreon! www.patreon.c...

3.01 Risk of COVID-19 Among Users of PPIs, Time to Treatment Initiation, & Dr. Lynora Saxinger

July 11, 2020 00:40 - 1 hour - 95.9 MB

This week we discuss recent research (and the accompanying Twitter thread) on the risk of COVID-19 among users of proton pump inhibitors (PPIs). We also hold a philosophical discussion on the research surrounding time to treatment initiation (TTI) in cancer medicine. We end the episode with an interview with Dr. Lynora Saxinger of the University of Alberta, Edmonton, a specialist in Infectious Diseases. PPIs and risk of COVID-19: https://twitter.com/BrennanSpiegel/status/1280527527325265920 ...

2.60 BONUS! Cancer Meta-Research 101: The Lay of the Land of Cancer Research

July 07, 2020 02:01 - 52 minutes - 50.6 MB

This BONUS episode is the recording of a lecture given on June 18, 2020 as part of Stanford's METRICS International Forum. METRICS stands for Meta-Research Innovation Center at Stanford University. This lecture is geared towards a broad audience and aims to provide a general sense of current cancer research. The lecture is titled "Cancer Meta-Research 101". Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

2.59 The Best Doctor, Selinexor, & Annotation Services for NGS with Drs. Katsoulakis and Kelley

July 03, 2020 20:46 - 1 hour - 72.2 MB

This week we respond to some listener feedback from Dr. Christopher Booth and use it to talk about how to be the best hematologist-oncologist. We also discuss the SADAL study on Selinexor for patients with relapsed refractory diffuse large B-cell lymphoma, as published in The Lancet Haematology. Finally, we interview Drs. Eva Katsoulakis and Michael Kelley on their recent paper out in the Journal of Clinical Oncology: Precision Oncology, titled "Comparison of Annotation Services for Next-Gene...

2.58 RECOVERY & Twitter, Academic Debate, and Transitioning Your Career with Dr. Andrae Vandross

June 27, 2020 02:33 - 1 hour - 74.9 MB

This week we briefly cover updates on the RECOVERY trial before segueing into an interview with Dr. Andrae Vandross on Twitter (specifically #medtwitter), academic discussions, and changing your career to find your calling. RECOVERY: www.recoverytrial.net/ Malignant audiobook: www.audible.com/pd/B08864KFHW/?so…ACX0_195112_rh_us Back us on Patreon! www.patreon.com/plenarysession

2.57 RECOVERY, Clinical Trials in the US, EFS, Writing, Dr. Raj Chetty, & Dr. Ian Tannock

June 19, 2020 22:17 - 2 hours - 125 MB

This week's episode is jam-packed with topics! We talk about the RECOVERY trial, the U.S. clinical trial infrastructure, event-free survival (EFS) and cost of care in acute myeloid leukemia, how long it takes to write papers in academic medicine, threats to public health officials, and the application to medicine of Dr. Raj Chetty's work in economics. Finally, we interview this week's special guest, Dr. Ian Tannock, on docetaxel, prostrate cancer, clinical trial appraisal, and his career in m...

2.56 HER2CLIMB & Misinformation and Disinformation with Dr. Cailin O'Connor

June 12, 2020 16:40 - 1 hour - 59.7 MB

This week we tackle the topic of tucatinib in HER2-positive breast cancer with brain metastases. We also interview Dr. Cailin O'Connor of the University of California Irvine on her research on misinformation and disinformation. We discuss her recent article in the Boston Review, titled "Hydroxychloroquine and the Political Polarization of Science", as well as her extensive body of work. HER2CLIMB: doi.org/10.1200/JCO.20.00775 Hydroxychloroquine: http://bostonreview.net/science-nature-politic...

2.55 Hydroxychloroquine for COVID-19, ASCO, QOTW, Private Equity in Medicine with Dr. Jane Zhu

June 05, 2020 02:28 - 2 hours - 122 MB

We start this week's episode by covering some recent research: After thoroughly critiquing the recent randomized trial of hydroxychloroquine for postexposure prophylaxis for COVID-19, we then discuss the five abstracts selected for plenary sessions at the recent virtual meeting of the American Society of Clinical Oncology. We transition from there to a Question from a Medical Student with Audrey Tran of Oregon Health & Science University on the recent decision to make the USMLE Step 1 exam pa...

2.54 Classical Hematology Chat on Thrombosis in COVID-19 & Drugs for COVID-19 with Dr. Walid Gellad

May 31, 2020 03:31 - 2 hours - 117 MB

This week we talk all things COVID-19! We start with an in-depth Classical Hematology Chat with Dr. Sven Olson and Dr. Joseph Shatzel of Oregon Health & Science University on thrombosis and anticoagulation in COVID-19, touching on a number of recent studies. We then turn to a conversation with Dr. Walid Gellad of the University of Pittsburgh on new pharmaceutical treatments for COVID-19. Tang et al. paper: doi.org/10.1111/jth.14768 Prospective autopsy study: doi.org/10.7326/M20-2566 COVID-19...

2.53 Why Agreeing 65% with Someone is Important & COVID-19 Health Policy with Dr. Daniel Morgan

May 23, 2020 02:11 - 1 hour - 61.9 MB

This week we discuss why being open-minded enough to agree partially with someone - instead of taking an all-or-nothing approach to a discourse - is important. We also sit down with epidemiologist Dr. Daniel Morgan of the University of Maryland School of Medicine to critique the public health policy concerning COVID-19 transmission. Back us on Patreon! www.patreon.com/plenarysession

2.52 Malignant Audiobook, PROfound trial, & Literature and Medicine with Dr. Adam Cifu

May 16, 2020 00:42 - 1 hour - 99 MB

This week we have an announcement -- the audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer", written and narrated by our host Vinay Prasad, is available now on Amazon, iTunes, and Audible! We also have an in-depth journal club for you on the findings of the PROfound trial as published in a new paper out in the New England Journal of Medicine titled "Olaparib for Metastatic Castration-Resistant Prostate Cancer". Finally, we end the episode with an interview with...

2.51 BONUS! Clinical Trials Part 3

May 13, 2020 16:06 - 1 hour - 55 MB

This BONUS lecture was a talk given to the Hematology/Oncology fellows at Oregon Health & Science University. It's part three of a three-part series on clinical trials. Back us on Patreon! www.patreon.com/plenarysession

2.50 Neil Ferguson, Ending Lockdown, & Updates on COVID-19 Management with Dr. Benjamin Singer

May 07, 2020 22:14 - 1 hour - 62.9 MB

This week's topic is all things COVID-19 -- we discuss the viral scandal of British epidemiologist Neil Ferguson's actions and how it reflects (or doesn't) on his work, we talk about the nuances of how to end lockdowns, and we bring back Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University, to address updates in the ICU management of COVID-19. Invisible Pandemic: doi.org/10.1016/S0140-6736(20)31035-7 Back us on Patreon! www.patreon.com/plenarysession

2.49 COVID-19 Contrarians, Remdesivir, & Book Club on "Malignant" with OHSU HemOnc Fellows

May 02, 2020 01:44 - 1 hour - 81.6 MB

This week we begin with a monologue on the recent controversy surrounding Dr. John Ioannidis's published opinions on the COVID-19 pandemic. We end with a group discussion with Oregon Health & Science University's Hematology/Oncology fellows on our host's, Vinay Prasad's, new book "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer." Expressing different views on COVID-19: https://www.statnews.com/2020/04/27/hear-scientists-different-views-covid-19-dont-attack-them/ Malignant:...

2.48 BONUS! Introduction to Malignant: How Bad Policy and Bad Evidence Harm People with Cancer

April 25, 2020 00:36 - 20 minutes - 19.8 MB

This week we have a BONUS episode for you! As a teaser to the forthcoming audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer" by Dr. Vinay Prasad (our host), Audrey Tran and Ian Straehley have set the introduction of the book to music they composed and arranged themselves. You can buy the print version of Malignant from Amazon: https://www.amazon.com/Malignant-Policy-Evidence-People-Cancer-dp-1421437635/dp/1421437635/ Back us on Patreon! www.patreon.com/plenar...

2.47 Remdesivir, Cloth Masks, & Incentives for COVID-19 Drug Development with Dr. Ameet Sarpatwari

April 16, 2020 23:22 - 1 hour - 76.6 MB

This week we start with an in-depth monologue on various new developments surrounding COVID-19, specifically the new study in NEJM on the compassionate use of remdesivir as well as the CDC's advice for the general public to wear cloth masks. We end with an interview with Dr. Ameet Sarpatwari of Harvard Medical School on how to create a more effective pharmaceutical system, the CREATES Act of 2019, developing fair and equitable drugs to treat COVID-19, and how to create a just system that bala...

2.46 Psychology Unearthed by COVID-19 Precautions & Polygenic Risk Score with Dr. Venk Murthy

April 11, 2020 00:47 - 1 hour - 87.4 MB

This week we have a far-reaching monologue on COVID-19 and how people are reacting to the public health recommendations concerning COVID-19 (such as cancelling conferences and school, maintaining 6+ feet of distance, wearing cloth masks). We end with an insightful interview with Dr. Venk Murthy on polygenic risk score and, at the end, a bit about how the world of science is failing to combat hype. Back us on Patreon! www.patreon.com/plenarysession

2.45 Viral Spread of SARS-CoV-2, Rationing Resources, "Evidence Fiasco", & Classical Hematology Chat

April 01, 2020 22:57 - 1 hour - 85.5 MB

This week we discuss several recent articles on the novel coronavirus (SARS-CoV-2) and COVID-19, specifically Dr. Siddhartha Mukherjee's article on the history and science of humanity's history with viruses, Dr. Ezekiel Emanuel's essay on how to fairly allocate dwindling medical resources during this global pandemic, and Dr. John Ioannidis's article on the "evidence fiasco" that has been our response to COVID-19. We end the episode with a Classical Hematology Chat with Drs. Sven Olson and Jos...

2.44 ICU Management of COVID-19 with Dr. Benjamin Singer

March 25, 2020 23:26 - 37 minutes - 36.1 MB

This week we discuss management of COVID-19 in the intensive care unit with Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University. We discuss medications, PPE, ventilators, and more! Back us on Patreon! www.patreon.com/plenarysession

2.43 BONUS! Novel Coronavirus and the COVID-19 Response in Oregon with Dr. John Townes

March 18, 2020 19:32 - 41 minutes - 37.6 MB

This bonus episode is an interview from March 16, 2020 with Dr. John Townes, the Interim Head for the Division of Infectious Disease and the Medical Director for Infection Prevention and Control here at Oregon Health & Science University. We talk about the novel coronavirus and how healthcare professionals are responding to the COVID-19 pandemic, with a focus on Oregon. Back us on Patreon! www.patreon.com/plenarysession

2.42 Quality-of-Life Measurement in Oncology, KnowYourTumor, & Question of the Week

March 17, 2020 00:33 - 1 hour - 66.8 MB

This week we discuss two recent papers -- one we praise, one we condemn -- and then we turn to a question of the week with medical student Audrey Tran on self-improvement and "refining conviction". The first paper is titled "Patient Experience Captured by Quality-of-Life Measurement in Oncology Clinical Trials" and the second is titled "Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor...

2.41 BONUS! Clinical Trials Part 2: Crossover and Control Arms

March 11, 2020 16:13 - 51 minutes - 48.5 MB

This BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health & Science University. It's part two of a three-part series on clinical trials. This talk is on clinical trial design, specifically crossover and control arms. Back us on Patreon! www.patreon.com/plenarysession

2.40 BEACON part 2, NALA, & Molecular Pathology and Next-Generation Sequencing with Dr. David Carr

March 05, 2020 20:40 - 1 hour - 68.8 MB

This week we revisit BEACON! The authors of the BEACON study have responded to the Letter to the Editor our host Dr. Vinay Prasad submitted to the New England Journal of Medicine, and we share our thoughts on what they said. We then turn to the FDA's recent approval of neratinib in combination with capecitabine for HER2-positive breast cancer, based on the phase III NALA trial. Finally, we interview Dr. David Carr, a Molecular Pathology Fellow at UC San Diego, on his work in general and, spec...

2.39 Effectiveness of Newer-Generation Antidepressants with Dr. Michael Hengartner

February 27, 2020 23:44 - 42 minutes - 58.6 MB

Our guest this week is Dr. Michael Hengartner of the Zurich University of Applied Sciences. We interview him on his work studying the long-term consequences and effectiveness of newer-generation antidepressants - specifically focusing on selective serotonin reuptake inhibitors (SSRIs). Back us on Patreon! www.patreon.com/plenarysession

2.38 KEYNOTE-048, Academic Currency, & Trials in Low/Mid-Income Countries with Dr. Bishal Gyawali

February 19, 2020 16:22 - 51 minutes - 51.4 MB

We start this episode by diving deep into KEYNOTE-048, the randomized, open-label, phase 3 study of pembrolizumab alone or with chemotherapy v.s. cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (HNSCC). We transition from there to a continued discussion on careerism in academia and how the motivation behind publishing papers should always stem from the drive to disseminate information, not from the drive to advance your own career. We end t...

2.37 Careerism, Presenting Abstracts, Twitter and the K-Index, & Classical Hematology Chat

February 14, 2020 23:11 - 1 hour - 70.3 MB

We have a full slate for you this week! We discuss careerism in medicine, presenting abstracts at conferences, #MedTwitter, and Dr. Califf's opinions on the K-Index. We conclude the episode with our first-ever Classical Hematology Chat, featuring our host Dr. Vinay Prasad, Dr. Sven Olson, and Dr. Joseph Shatzel. The chat is on sickle cell disease. "A Perspective on the K-Index": doi.org/10.1016/j.jaccas.2020.01.003 Back us on Patreon! www.patreon.com/plenarysession

2.36 Thought Leaders, NELSON, & Reliance on P Values in Cancer Trials with Dr. Sam Rubinstein

February 07, 2020 23:09 - 59 minutes - 57.7 MB

This week we discuss the concept of "thought leaders" and we examine the conclusions about volume CT screening for lung cancer from the NELSON trial. We end with an interview with Dr. Sam Rubinstein, a hematology/oncology fellow at Vanderbilt University Medical Center, on his new paper published in JAMA Network Open titled "Indication of Measures of Uncertainty for Statistical Significance in Abstracts of Published Oncology Trials: A Systematic Review and Meta-analysis". NELSON: doi.org/10.1...

2.35 BONUS! How to Keep Up with the New Information in Medicine

January 31, 2020 20:07 - 1 hour - 50.4 MB

This BONUS episode is the recording of a lecture given to medical students titled "How to Keep Up with the New Information in Medicine." It's a primer on the steps healthcare professionals need to take in order to keep abreast of the latest medical findings. Vinay's new book, Malignant: www.amazon.com/Malignant-Policy-…cer/dp/1421437635 Back us on Patreon! www.patreon.com/plenarysession

2.34 Red Light, Pola for DLBCL, Hem/Onc Question of the Week, & TAILORx with Dr. Ali Khaki

January 24, 2020 21:51 - 1 hour - 93.1 MB

We have a variety of topics for you this week! We tackle red light therapy, polatuzumab olatuzumab vedotin in relapsed or refractory diffuse large b-cell lymphoma; we have a hematology/oncology question of the week from Dr. Emerson Chen of OHSU; and we sit down with Dr. Ali Khaki of the Fred Hutchinson Cancer Research Center to discuss his recent paper critiquing TAILORx. Pola for DLBCL: doi.org/10.1200/JCO.19.00172 Financial COI on Twitter: doi.org/10.1001/jamainternmed.2016.8467 Ignoring V...

2.33 Olaparib and POLO & the Classical Fallacies of Cancer Screening with Dr. H Gilbert Welch

January 15, 2020 23:10 - 1 hour - 67.9 MB

This week we're treating you to a recording of the Grand Rounds lecture on overdiagnosis and cancer screening that Dr. H Gilbert Welch gave at Oregon Health & Science University on October 30, 2019. Before the lecture, we take a moment to reiterate with renewed vigor our distaste for the POLO trial (first discussed in episode 1.64). POLO: doi.org/10.1056/NEJMoa1903387 Back us on Patreon! www.patreon.com/plenarysession

2.32 BONUS! Clinical Trials Part 1: Thinking Better About Cancer Medicine

January 10, 2020 23:00 - 53 minutes - 49.2 MB

This BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health & Science University. It's part one of a three-part series on clinical trials, titled "Thinking Better About Cancer Medicine". Back us on Patreon! www.patreon.com/plenarysession

2.31 Listener Questions, Responsibility of Reviewers, & Duration of Response with Dr. Bishal Gyawali

January 07, 2020 23:51 - 40 minutes - 38.1 MB

This week we answer a few questions: the first is from Patreon backer, Harry Hong, on Kaplan-Meier curves. The second is from a student at Mount Sinai Medical School who reached out with some ethical questions they had after the ASH annual meeting on the obligations and responsibilities of peer reviewers. Finally, we end the episode with an interview with Dr. Bishal Gyawali of Queens University in Kingston, Ontario, Canada on his new paper out today in the Journal of the National Comprehensiv...

2.30 Questions from a Medical Student & Epidemiology with Dr. Ellie Murray

January 03, 2020 23:18 - 1 hour - 100 MB

This week we return to our discussion of going after soft targets vs hard targets, but this time with a focus on how it applies to building a burgeoning career in medicine, in our segment Questions from a Medical Student with Audrey Tran. We end this week's episode with a far-reaching interview with Dr. Ellie Murray (most people know her as Epi Ellie on Twitter and as the co-host of the podcast Casual Inference) on all things epidemiology. Check out Dr. Murray's excellent podcast here: https...

2.29 Time from Diagnosis to Treatment in AML and Real-World Data with Dr. Sherrie Aspinall

December 27, 2019 17:56 - 1 hour - 64.3 MB

This week we wonder incredulously how this abstract from ASH titled "Time from diagnosis to treatment does not affect outcome in intensively treated patients with newly diagnosed acute myeloid leukemia" was selected as one of the top abstracts from the conference. In the second half of the episode we interview Dr. Sherrie Aspinall of the Veterans Administration on how to use real-world data. Her new paper is titled "Use of targeted therapies for advanced renal cell carcinoma in the Veterans H...

2.28 Trastuzumab in Later Lines of Therapy for HER2+ Breast Cancer, Kaplan-Meier Curves, & Patreon

December 20, 2019 18:54 - 1 hour - 65.6 MB

We're back in Plenary Session HQ! We have multiple topics for you this week. We cover the use of trastuzumab in later lines of therapy for HER2+ metastatic breast cancer, we take a listener question on Kaplan-Meier curves, and we talk a little about Patreon. Malignant: www.amazon.com/Malignant-Policy-Evidence-People-Cancer/dp/1421437635 Back us on Patreon! www.patreon.com/plenarysession

2.27 BONUS! Use of Bone-Modifying Agents Among Medicare Beneficiaries with MM with Dr. Arjun Gupta

December 12, 2019 17:31 - 26 minutes - 24.3 MB

This BONUS episode is an interview with Dr. Arjun Gupta, a second-year hem/onc fellow at Johns Hopkins University, on his new paper out TODAY in JAMA Oncology titled ''Use of Bone-modifying Agents among Medicare Beneficiaries with Multiple Myeloma''. Use of bone-modifying agents: doi.org/10.1001/jamaoncol.2019.5426 Back us on Patreon! www.patreon.com/plenarysession

2.26 Questions of the Week: Hematology/Oncology, USMLE Step 2 CK, & a bonus Hematology/Oncology

December 09, 2019 19:39 - 40 minutes - 39.2 MB

This is the last week of pre-recorded episodes -- we'll be back next week with a fresh, hard-hitting monologue. In the meantime, we have three questions of the week for you. Two are inspired by the hematology/oncology boards and are presented by Dr. Sven Olson. Between the two, we have one from Ian Straehely that's inspired by the USMLE Step 2 CK. Back us on Patreon! www.patreon.com/plenarysession

2.25 Questions of the Week: Hematology/Oncology, the USMLE Step 2 CK, & One From a Med Student

December 02, 2019 19:02 - 47 minutes - 45.5 MB

Our host is still out of town, but don't worry -- we have some questions of the week to tide you over. The first is inspired by the hematology/oncology boards, presented by Dr. Sven Olson; the second is inspired by the USMLE Step 2 CK, presented by Ian Straehley; and the third is from Audrey Tran, inspired by her experiences as a med student. Back us on Patreon! www.patreon.com/plenarysession

2.24 Questions of the Week: the USMLE Step 2 CK, Hematology/Oncology, & One From a Med Student

November 26, 2019 14:59 - 37 minutes - 36.6 MB

This week our host is still in Australia, but we have some questions of the week saved for you! The first is inspired by the USMLE Step 2 CK, presented by Ian Straehley; the second is inspired by the hematology/oncology boards, presented by Dr. Sven Olson; and the third is from Audrey Tran, inspired by her experiences as a med student. Back us on Patreon! www.patreon.com/plenarysession

2.23 Question of the Week & Ethics and Inefficiencies of Clinical Trials with Dr. Jonathan Kimmelman

November 20, 2019 18:21 - 58 minutes - 55.4 MB

First up this week is Question of the Week inspired by the Hematology/Oncology boards, with Dr. Sven Olson. No monologue on current trials this week because our host is still in Australia, so we conclude the episode with an interview with Dr. Jonathan Kimmelman of McGill University on his extensive work in research ethics, studying the most important issue in cancer medicine today: the risk-benefit of clinical trials and how best to spare patients from the burdens of creating a new drug. Re...

2.22 Question of the Week & EMR, Talking to Patients, and Being a Doctor with Dr. Robert Hirschtick

November 15, 2019 00:13 - 56 minutes - 50.4 MB

This week we have a question of the week from Ian Straehley, inspired by the USMLE Step 2 CK, as well as an interview with Dr. Robert Hirschtick of Northwestern University on what it means to be a doctor, how you should think as a physician, and his many popular pieces published in journals like JAMA. "Copy-and-Paste": doi.org/10.1001/jama.295.20.2335 "Extremities": doi.org/10.1001/jama.300.10.1125 "The Quick Physical Exam": doi.org/10.1001/jama.2016.8182 Robiewon on YouTube: www.youtube.co...

2.21 Aiming for the Hard Targets & Harm From Screening and Overdiagnosis with Dr. H Gilbert Welch

November 08, 2019 18:30 - 2 hours - 131 MB

We begin this week's episode by addressing a listener's feedback to our discussion of smoldering multiple myeloma. We then expand on our critique of 'going after the soft targets' (criticizing studies that fall apart with little resistance) by elucidating how to identify and go after hard targets and why it's so important that you do. Finally, we launch into an interview with Dr. H Gilbert Welch that explores his tremendous body of work on the preventable harm that comes from too generous a h...

2.20 "Courageous Skeptics", Lenalidomide, QOTW, and a Political Conversation with Dr. Andy Saultz

November 01, 2019 23:55 - 2 hours - 161 MB

We begin this week's episode with a thoughtful discussion of the internet's "courageous skeptics". Then, after lamenting the way in which the recent study "Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma" was conducted, we end with an interview with Dr. Andy Saultz on his ongoing campaign for Oregon state representative. We break up the interview with a couple Hem/Onc boards questions of the week from Dr. Emerson Chen. Lenalidomide in Smoldering Multiple M...

2.19 Remembering Dr. Bernard Fisher & Self-Diagnosis with Dr. Mark Lewis

October 25, 2019 19:20 - 2 hours - 123 MB

This week we give a short monologue on the late Dr. Bernard Fisher's legacy in the field of oncology, and then dive into a far-ranging interview with Dr. Mark Lewis of Intermountain Healthcare on his career, his family, and diagnosing himself with MEN1 syndrome. Dr. Fisher's obituary in the New York Times: https://www.nytimes.com/2019/10/19/science/dr-bernard-fisher-dead.html Back us on Patreon! www.patreon.com/plenarysession

Guests

Mark Lewis
1 Episode

Twitter Mentions

@brennanspiegel 1 Episode