Plenary Session
386 episodes - English - Latest episode: 11 days ago - ★★★★★ - 722 ratingsA podcast on medicine, oncology, & health policy.
Host: Vinay Prasad, MD MPH from University of California San Francisco.
Tweet your feedback to @Plenary_Session or e-mail [email protected]
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Episodes
4.61 - How CDC's Vaccine Safety Missed Cases Of Myocarditis
May 27, 2022 00:43 - 54 minutes - 125 MBI am joined by Dr. Katie Sharff, infectious disease doc, to discuss two of her papers on myocarditis after COVID-19 vaccination. https://doi.org/10.1016/j.amjcard.2022.02.039 https://doi.org/10.1101/2021.12.21.21268209
4.60 - NEW JCO paper - AML, EFS, CR, CRi, and Surrogate validation - FDA & Methods
May 21, 2022 18:09 - 34 minutes - 31.3 MBI get back to my roots; I explain surrogate validation and a new JCO paper from the FDA authors on EFS and OS in AML. You won't want to miss it
4.59 - How to be a better reader of case control studies
May 17, 2022 04:06 - 18 minutes - 17.3 MBIn this episode I dissect a test negative case control trial; I talk about a famous pancreas cancer study and I revisit the failure of Myeloma trialists
4.58 - Myeloma is a broken field - New BLOOD Paper!
May 14, 2022 18:19 - 1 hour - 57.5 MBI am joined by Manni Mohyuddin to talk about How I treat frontline transplant eligible myeloma. Vinay Prasad makes the case the entire field of myeloma is corrupt and broken.
4.57 - COVID19 and the Failures of Public Health w/ Leslie Bienen
May 06, 2022 17:48 - 1 hour - 74.7 MBI join Dr. Bienen in person to discuss COVID19 and failures in public health
Fifth Installment of the brilliant Zeb Jamrozik
May 04, 2022 01:30 - 77.3 MBID ethicist, and brilliant COVID19 commenter
4.56 - Fifth Installment of the brilliant Zeb Jamrozik
May 04, 2022 01:30 - 1 hour - 77.3 MBID ethicist, and brilliant COVID19 commenter
4.55 - Compilation Of Recent Covid Monologues
May 01, 2022 04:21 - 1 hour - 66.7 MBThis is a compilation of the last week and half of monologues by VP on his Youtube Channel about COVID19 policy
4.54 - Eric Collison Professor, GI Oncologist, Physician Scientist
April 30, 2022 01:35 - 49.8 MBI talk to UCSF Professor Eric Collison about his lab, grant writing, the physician scientist life, cancer, and a doctors duty.
4.54 - Eric Collisson Professor, GI Oncologist, Physician Scientist
April 30, 2022 01:35 - 54 minutes - 49.8 MBI talk to UCSF Professor Eric Collison about his lab, grant writing, the physician scientist life, cancer, and a doctors duty.
John Ioannidis lectures the VKPrasad Lab about COVID19
April 27, 2022 19:02 - 81.4 MBA brilliant talk by one of the most brilliant scientists alive; JPAI lectures VKPrasad lab on all things COVID19; When does the pandemic end? What are the lessons?
4.53 John Ioannidis lectures the VKPrasad Lab about COVID19
April 27, 2022 19:02 - 1 hour - 81.4 MBA brilliant talk by one of the most brilliant scientists alive; JPAI lectures VKPrasad lab on all things COVID19; When does the pandemic end? What are the lessons?
4.52 Vinay Prasad Gives a Lecture on COVID19 to a General Audience
April 24, 2022 16:09 - 41 minutes - 38.2 MBListen in as I give an unscripted lecture to a general audience about COVID-19; What we got right and wrong these last 2+ years.
4.51 - Vinay Prasad is Interviewed by Kristina Jenei About Academic Medicine
April 22, 2022 03:24 - 1 hour - 72.8 MBKristina Jenei becomes the 4th guest host and flips the tables on me, interviewing me about academic medicine and more...
4.50 - Ivosidenib & Aza vs Aza, the AGILE, 6 huge problems; Journal club
April 21, 2022 06:32 - 19 minutes - 18.2 MBI perform an analysis of the AGILE trial that came out in NEJM today; I find 6 huge problems. Follow PS on twitter; and write to us to let us know what you think
4.49 - Malignant Book Club Part 3 Audio
April 15, 2022 03:47 - 44 minutes - 40.5 MBTimothee Olivier joins me for the 3rd of 9 parts of the Malignant book club - this covers all of Oncology
4.48 - The Truth About RCTs In Cancer Medicine
April 07, 2022 21:13 - 34 minutes - 31.7 MBPragmatic vs Ideal, Surrogate vs. Hard Endpoints; Time it takes; Ethics; Control arms; Purpose; I cover it all here.
4.47 Malignant Book Club w/ Dr. Olivier Part 2 of 9
March 22, 2022 00:24 - 51 minutes - 47.4 MBIn this book club we discuss Chapters 2 and 3 of Malignant, covering Surrogates and their role in Oncology
Malignant Book Club w/ Dr. Olivier Part 2 of 9
March 22, 2022 00:24 - 47.4 MBIn this book club we discuss Chapters 2 and 3 of Malignant, covering Surrogates and their role in Oncology
4.46 - Cancer Monologue and Lecture #5 from VP's Class on How to Appraise Medical Literature
March 16, 2022 23:19 - 50 minutes - 46.7 MBThis is a brief monologue with Dr. Timothee Olivier, and the audio from a class I taught on RCTs-- when are they needed in biomedicine
4.45 - Malignant Book Club w/ Dr. Olivier Part 1 of 9
March 12, 2022 00:42 - 1 hour - 58.2 MBHere is the first of a 9 part series on Malignant Book Club with Timothee Olivier from Switzerland We cover cost of drugs, and intro to cancer drug policy
4.44 - Cost Of Cancer Drugs - Basics In Cancer Drug Policy
March 04, 2022 01:02 - 43 minutes - 40 MBI lecture on basics on cancer drug policy
4.43 - VKPrasad Lab Update Part 2 With Timothee Olivier
March 01, 2022 00:11 - 1 hour - 61.2 MBI am back with Timothee Olivier from Geneva Switzerland to discuss Part 2 of our laboratory work. Can oncologists criticize RCTs? We also announce our new series. A 9 week Malignant Bookclub
4.42 - Timothee Olivier, Geneva in the first Installment of VKPrasad Lab updates
February 24, 2022 20:18 - 1 hour - 60.3 MBTimothee Olivier from Geneva Hospital Switzerland joins me for the first in a series of episodes on updates from VKPrasad laboratory, where we discuss cancer drugs & policy & evidence
4.41 The Mask Debacle with Jacob Hale Russell
February 19, 2022 01:40 - 1 hour - 61.3 MBJacob Hale Russell is back from Rutgers law to talk about his new piece in Tablet Magazine.
4.40 H Gilbert Welch - Melanoma Screening; Blood Based Cancer testing; Lung CA screening
January 28, 2022 15:47 - 1 hour - 58.1 MBA discussion about the excesses of testing with Gil Welch
4.39 Dr Zeb Jamrozik, ID ethicist, practicing doctor, great thinker
January 27, 2022 01:51 - 1 hour - 84.2 MBI am joined for my 4th conversation with Zeb. This is a far reaching conversation where we discuss mandates, vaccines, masking, and why evidence based medicine still has something to offer.
4.38 COVID-19: Boosters for Adults and Teens, Paul Offitt, Testing, Myocarditis, Campus Restrictions
January 21, 2022 03:05 - 2 hours - 122 MBWe're back this week with a collection of monologues! We talk about a Paul Offitt quote, COVID boosters for adults and kids, COVID testing, whether this is a pandemic of the unvaccinated, myocarditis and pericarditis, college campus restrictions, and more! STAT News Op-Ed: https://www.statnews.com/2021/12/23/at-a-time-when-the-u-s-needed-covid-19-dialogue-between-scientists-francis-collins-moved-to-shut-it-down/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube chann...
4.37 MEMOIR & The Emperor Has No Clothes (a Critique of Cancer Care) with Dr. Christopher Booth
January 06, 2022 22:22 - 56 minutes - 44.5 MBToday we have a short discussion for you of the MEMOIR study, published in The Lancet Oncology: "Effect of immunotherapy time-of-day infusion on overall survival among patients with advanced melanoma in the USA (MEMOIR): a propensity score-matched analysis of a single-centre, longitudinal study". We also have a special treat for you: a lecture Dr. Chris Booth of Queen's University, Kingston, Ontario, Canada recently gave titled "The Emperor Has No Clothes", a critique of the current state of ...
4.36 Where Are We Now with COVID-19? with Dr. John Ioannidis
January 04, 2022 20:00 - 1 hour - 105 MBToday we have an in-depth, in-person interview with Dr. John Ioannidis of Stanford University. We ask him: where are we now with COVID-19? Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.35 Omicron, Travel Bans, Masks, Vaccine Mandates with Dr. Zeb Jamrozik
December 31, 2021 22:19 - 1 hour - 77.5 MBDr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back again! We discuss Omicron, travel bans, masks, vaccine mandates, and more. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.34 - ASH Lymphoma Updates: POLARIX, ZUMA 7, BELINDA w/ Papa Heme and DRG
December 24, 2021 16:54 - 103 MBDavid Russler-Germain and Papa Heme join VP to discuss the hottest ASH lymphoma papers: POLARIX and 2 CAR-T trials (ZUMA-7 & BELINDA)
4.34 ASH Lymphoma Updates: POLARIX, ZUMA 7, BELINDA w/ Papa Heme and DRG
December 24, 2021 16:54 - 1 hour - 103 MBDavid Russler-Germain and Papa Heme join VP to discuss the hottest ASH lymphoma papers: POLARIX and 2 CAR-T trials (ZUMA-7 & BELINDA) Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.33 Melanoma: Tebentafusp, Stage Migration, Adjuvant Therapy, Training with Dr. Adil Daud
December 22, 2021 04:05 - 1 hour - 59.9 MBWe have an in-person interview for you today! We sit down with Dr. Adil Daud of UCSF to talk all things melanoma. We cover Tebentafusp, nodal dissection, the Will Rogers phenomenon and the effect of stage migration on clinical trials as imaging advances, adjuvant vs I/O, academic training vs apprenticeship for budding oncologists, and more! Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.32 Oral Azacitidine for AML and Nelarabine for T-ALL with Dr. Bernard Marini
December 03, 2021 03:47 - 1 hour - 59.9 MBWe're back with a hematology/oncology heavy episode! We talk about oral azacitidine for acute myeloid leukemia (AML) and nelarabine for T-cell acute lymphoblastic leukemia (T-ALL) with Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology and Associate Professor at University of Michigan Medicine. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.31 Neoadjuvant Radiation Therapy in Pancreatic Adenocarcinoma with Dr. William Hall
November 24, 2021 20:00 - 54 minutes - 47.5 MBToday we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on his new paper out now in the Journal of Clinical Oncology titled "Value of Neoadjuvant Radiation Therapy in the Management of Pancreatic Adenocarcinoma". Neoadjuvant: doi.org/10.1200/JCO.21.01220 Back us on Patreon! www.patreon.com/plenarysession
4.30 COVID in Children and the US FDA Vaccine Advisory Committee with Dr. Cody Meissner
November 22, 2021 04:26 - 1 hour - 58.5 MBToday we interview Dr. Cody Meissner, Chief of the Division of Pediatric Infectious Disease and Professor of Pediatrics at Tufts University School of Medicine. Dr. Meissner is also a member of the US FDA Vaccine Advisory Committee. We talk about the affect of school closures on the health of children, the evidence base for COVID vaccine mandates in children, and the nuance surrounding all of it. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.c...
4.29 Scientific and Ethical Failures of COVID-19 with Dr. Zeb Jamrozik
November 11, 2021 01:23 - 1 hour - 66 MBDr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back by popular demand! We talk about the failures, both scientific and ethical, of the COVID-19 pandemic. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.28 Calling Out Unethical Clinical Trials, Melflufen, and Academic Oncology with Dr. Aaron Goodman
November 06, 2021 04:48 - 55 minutes - 46.1 MBWe're joined today by Dr. Aaron Goodman, a hematologist/oncologist at the University of California San Diego, to talk about calling out an unethical clinical trial, Melflufen, and academic oncology. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.27 Economics and Medicine with the Host of Freakonomics, M.D., Dr. Anupam Bapu Jena
October 29, 2021 21:01 - 1 hour - 69.4 MBWe're joined by Dr. Bapu Jena of Harvard Medical School to talk about his show, Freakonomics, M.D., and his career at the intersection of economics and medicine. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.26 Recent Kidney Cancer Trials, Unethical Cancer Clinical Trial, & CASSIOPEIA
October 28, 2021 04:06 - 34 minutes - 33.2 MBWe have three topics for you today: We talk about our recent paper on the use of second-line immunotherapy in kidney cancer, the controversy over whether a cancer clinical trial was unethical, and the results of the randomized clinical trial CASSIOPEIA. Kidney Cancer: doi.org/10.1001/jamanetworkopen.2021.24728 CASSIOPEIA doi.org/10.1016/S1470-2045(21)00428-9 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.25 A Critique of COVID-19 Health Policy with Infectious Disease Ethicist Dr. Zeb Jamrozik
October 20, 2021 00:58 - 1 hour - 60.8 MBToday we have an interview with Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford. We talk about COVID-19 health policy and where we went wrong, speaking specifically from the values framework of health, fairness, and freedom. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.24 COVID-19: Moderna booster, Myocarditis, Progressivism, Social Media, Masks, Tests, J&J booster
October 16, 2021 03:31 - 1 hour - 101 MBWe have a summary of our thoughts for you on recent news about COVID. We discuss the prospect of FDA authorization of a Moderna booster, 8 lessons for health policy in times of crisis, updates on myocarditis data from Israel and Europe, how our experiences with COVID warn us of the possible end to democracy, how progressivism is dead, why social media should not censor views, the CDC's new masking studies, the slogan "follow the science", weekly testing of vaccinated college students who don...
4.23 Access to Cancer Medicines, Standard of Care in Oncology, and the Oncology Value Paradigm
October 15, 2021 03:23 - 1 hour - 73.6 MBOn today's episode we're joined by a number of special guests: Dr. Christopher Booth and Dr. Adam Fundytus of Queen's University in Kingston, Ontario, Dr. Manju Sengar of the Tata Memorial Centre, and Dr. Aaron Goodman of the University of California at San Diego. We talk about their new papers: "Access to cancer medicines deemed essential by oncologists in 82 countries: an international, cross-sectional survey", "Practicing on the edge of oncology: when standard of care feels uncomfortable",...
4.22 Honoring Dr. Elilhu Estey and His Decades-Long Oncology Career
October 12, 2021 05:24 - 1 hour - 74.5 MBOn today's episode, in honor of him and in recognition of his passing, we have an old interview with Dr. Elihu Estey of the University of Washington on his 40 years of experience as an oncologist, the "Renaissance" of drugs for leukemia, and advice for trainees on how to approach career goals. This interview originally aired as episode 1.49. He will be missed.
4.21 Cognitive Errors in Medical Decision-Making with Dr. Daniel Morgan & COVID-19 Policy
September 22, 2021 23:00 - 1 hour - 80.2 MBThis week we take a break from #zercovid to give you another episode that's a deep dive into COVID-19. We start with an interview with epidemiologist and infectious disease expert Dr. Daniel Morgan of the University of Maryland School of Medicine; we talk about cognitive errors in medical decision-making and how it relates to COVID-19 health policy. After that, we have a series of thoughts for you on COVID vaccine mandates for schools, President Biden's vaccine plan, the FDA's vote on booster...
4.20 Vaccinating Kids and College Students, Boosters, Outdoor Masking, Bangladesh RCT, & more!
September 14, 2021 04:11 - 1 hour - 62.1 MBToday we take a brief break from our #zerocovid mantra to offer you our thoughts on current events. We cover a variety of topics, including: medical doctors in academia, cancelling conferences even for the vaccinated, masking 2-year-olds, equipoise, the CDC Georgia study, myocarditis, booster shots, outdoor masking at Duke, no more zero COVID in Australia, the Bangladesh cluster RCT on masks and its implications for kids in the USA, the resignation of two senior FDA officials, LA schools mand...
4.19 Censoring: Not on Facebook, but in Kaplan-Meier Curves
September 08, 2021 04:18 - 30 minutes - 27.6 MBToday's episode is a lecture our host, Dr. Vinay Prasad of University of California San Francisco, gave recently on censoring patients in Kaplan-Meier plots. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew
4.18 Dementia Interventions, Skills for Epidemiologists, & Aducanumab with Dr. Maria Glymour
September 01, 2021 02:10 - 1 hour - 74.9 MBToday we're joined by social epidemiologist, Dr. Maria Glymour of UCSF. We talk about her work in studying public health interventions for dementia and how her experience in academia has led to her conviction in the necessity of rigorous, quantitative technical skills training for epidemiology PhD students. We touch on how to have a good idea, her advice for PhD applicants, and working in a soft money (grants) vs hard money environment. Finally, we discuss her idea for a stepped-wedge trial a...
4.17 RCTs for Cancer Drug Approval with Dr. Saroj Niraula & Myeloma Studies with Dr. Manni Mohyuddin
August 27, 2021 04:42 - 59 minutes - 48.2 MBWe have two oncology conversations for you today. The first is with Dr. Saroj Niraula of the University of Manitoba, and together we discuss the necessity of randomized controlled trials for granting FDA approval of cancer drugs. The second is with Dr. Ghulam Rehman "Manni" Mohyuddin of the University of Utah on a variety of myeloma studies, including LIGHTHOUSE, OCEANS, and HORIZON. Feasibility of RCTs: doi.org/10.1093/jncics/pkab061 RR of Alternative Treatments: doi.org/10.1002/ijc.33231 S...