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Plenary Session

386 episodes - English - Latest episode: 12 days ago - ★★★★★ - 722 ratings

A podcast on medicine, oncology, & health policy.
Host: Vinay Prasad, MD MPH from University of California San Francisco.
Tweet your feedback to @Plenary_Session or e-mail [email protected]

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Episodes

5.32 - ASH Update #1 - Talquetamab NEJM

December 11, 2022 19:39 - 17 minutes - 16.3 MB

Is it acceptable to take someone with myeloma who has gotten just 2 regimens and put them on a phase 1? VP says hell no.

5.31 - MUST LISTEN Grand Rounds - COVID19 Updates

December 08, 2022 18:59 - 55 minutes - 50.1 MB

In this lecture given December 7, 2022, I cover 5 things: Vaccines Masking Long COVID Schools/Immunity Debt Paxlovid

5.30 Rajkumar vs Goodman; Long COVID vs Long URI

December 03, 2022 20:19 - 40 minutes - 74.3 MB

Should we treat smoldering MM, a debate Long COVID vs Long URI Review the show; Say Hi at ASH22

5.29 Smart Start is a useless Lymphoma study

November 27, 2022 01:13 - 49 minutes - 91.3 MB

Smart Start is a useless lymphoma study; We have to stop putting our careers ahead of patients. In the second part, I discuss the 'experts' featured on STAT. Wowzers. I will be at ask. Hit me up: [email protected]

5.28 - Pandemic Amnesty or Accountability with Paul Fenyves

November 12, 2022 03:26 - 38 minutes - 70 MB

I am joined by Cornell Professor Paul Fenyves; a practicing internist Dr. Fenyves walks us through COVID19 policy. We will be back soon with more cancer medicine. Including a devastating lymphoma one.

5.27 - Multiple Myeloma - Do Our Trials Help Patients?

November 08, 2022 21:24 - 28 minutes - 51.9 MB

I was invited to give this talk to a UK conference on Myeloma Please LEAVE A REVIEW of this podcast

Multiple Myeloma - Do Our Trials Help Patients?

November 08, 2022 21:24 - 28 minutes - 51.9 MB

I was invited to give this talk to a UK conference on Myeloma Please LEAVE A REVIEW of this podcast

5.26 - Hawaii Oncology Association Keynote Lecture

November 06, 2022 16:12 - 44 minutes - 80.6 MB

Lecture I gave this weekend in Hawaii to the Medical Oncology Association; One of the best audiences I've had

5.25 - Neurosurgery Grand Rounds by Vinay Prasad

November 03, 2022 04:36 - 1 hour - 132 MB

I give Grand Rounds to UCSF Neurosurgery on how to read and interpret Neurosurgery Studies (Video and slides coming soon to YouTube) Also I discuss Bob Califf's Promotion of Paxlovid

5.24 Vlad Kogan is back to discuss Kids Test Scores

November 01, 2022 14:25 - 1 hour - 146 MB

Learning Loss is Devastating; Here are the data and what it means

5.24 - Gerald Hsu MD PhD UCSF Heme Onc Program Director

October 28, 2022 03:02 - 1 hour - 125 MB

Learn about UCSF Hematology Oncology Program with Dr. Gerald Hsu, MD PhD Malignant Heme and Program Director

5.23 - Subclinical Myocarditis

October 19, 2022 23:30 - 12 minutes - 23.1 MB

A new study from Switzerland confirms the rate of subclinical myocarditis

5.23 - ID Ethicist joins me for a 6th discussion of COVID19 policy

October 18, 2022 16:07 - 1 hour - 163 MB

LONG COVID, Vaccines, Paxlovid and More

5.22 NordICC trial interview with PI Michael Bretthauer - Offer but don't Nudge

October 15, 2022 00:59 - 1 hour - 126 MB

discuss NordICC with the trial PI Power calc specified 50% non-adherence ADR is on par with US studies from the time Colo quality good Perf rate lower than US! How does he counsel individuals & governments What he thinks of USPSTF

5.21 Science Mag Editor Condemns Ladapo But Silent About Jha

October 14, 2022 03:19 - 34 minutes - 32 MB

A double standard to condemn data with limitations, based on political party, will destroy medicine. We will back to oncology soon, but this is important

5.20 The Great Colonoscopy Debate

October 11, 2022 18:00 - 1 hour - 112 MB

Cifu, Mandrola and Prasad fight about colonoscopy

5.19 - NEJM's first ever RCT of Colonoscopy-- Explained

October 09, 2022 22:23 - 30 minutes - 56.5 MB

I break down the history and data for the first ever randomized trial of colonoscopy, appearing in NEJM on Oct 9, 2022

5.18 Lecture to Heme Onc Fellows - POLO; Javelin 100 bladder

October 08, 2022 15:39 - 46 minutes - 85.5 MB

Polo Javelin 100 bladder Crossover Control arms How to read and keep up with the literature

5.17 - The State Of Precision Oncology

October 07, 2022 00:48 - 15 minutes - 27.5 MB

Invited Lecture to Cancer Center Directors

5.13 - The State Of Precision Oncology

October 07, 2022 00:48 - 15 minutes - 27.5 MB

Invited Lecture to Cancer Center Directors

5.16 - Aaron Goodman UCSD

September 29, 2022 19:54 - 1 hour - 173 MB

I travel to UCSD to interview Dr. Goodman about myeloma, celebrity oncology culture, his career, education, patient care, choosing a specialty and more.

5.15 - How To Apply For And Get Your Perfect First Job

September 21, 2022 21:40 - 36 minutes - 66.2 MB

Based on listener questions, I discuss how to apply for and get your first job.

Unspoken Rules of Oncology - Malignant BC Part 6

September 18, 2022 00:21 - 1 hour - 115 MB

T.O. joins me for the missing episode. These are the unspoken rules of Oncology; We dive deeper into Malignant Book Club.

Malignant Book Club - Episode 7 - famous trials

September 09, 2022 16:28 - 41 minutes - 76.3 MB

Timothee Olivier joins me for the 7th installment of our book-club We cover famous trials in oncology

5.12 - Academics Vs Industry - A.Goodman S.Loghavi D.Steensma V.P.

September 03, 2022 01:35 - 1 hour - 164 MB

How do careers vary between the academy and industry? We have a panel of the best: Sanam Loghavi from MD Anderson, Aaron Goodman UCSD, and David Steensma Novartis (formerly Farber/ Mayo) and VP #Real talk

5.11 - Malignant Book Club - Part 5

August 26, 2022 00:38 - 52 minutes - 48.2 MB

Timothee Olivier joinrs me as we explore part 3 of the book Crossover, sample size, observational vs RCTs

5.10 - Adam Cifu on clinical excellence

August 24, 2022 15:57 - 1 hour - 62.3 MB

Adam Cifu is here to discuss clinical excellence and his new podcast

5.09 - Malignant Book Club Part 4

August 22, 2022 00:25 - 1 hour - 55.1 MB

T.O. joins me to grill me on the rest of Financial Conflict of Interest and Precision Oncology. We discuss the need for randomization, and when it can be omitted. A must listen for Oncology Fans.

5.08 - LaceWing RCT Phase 3 Blood - Spin Cycle

August 18, 2022 16:44 - 33 minutes - 61.4 MB

VP discusses the LaceWing study in Blood. A Phase 3 RCT of GILT AZA vs AZA; Medical writers; confounding; table 1; balance; and so much more

5.07 - Plenary Session Alps Edition

August 10, 2022 06:36 - 58 minutes - 54 MB

Timothee Olivier joins me to discuss recent papers: IMPOWER10 Checkmate 816 Path CR/ EFS/ Surrogates Drug Dosing, cGCSF rules and more Bread and butter oncology

5.06 - POLO trial now has OS results - OMG

July 21, 2022 01:03 - 30 minutes - 28.1 MB

The POLO trial, which we first broke on PS Season 1- is back with null OS results. But the trial authors enter the spin cycle. VP goes line by line.

5.05 - Citations, Metrics, Rankings in Oncology & Medicine

July 18, 2022 05:38 - 36 minutes - 33.5 MB

VP explains H index, total cites, papers, US News and World Report rankings and how evaluates researchers and doctors.

5.04 - Citations, Metrics, Rankings in Oncology & Medicine

July 18, 2022 05:38 - 36 minutes - 33.5 MB

VP explains H index, total cites, papers, US News and World Report rankings and how evaluates researchers and doctors.

5.04 - Echelon 1 reports OS benefit - But does it add up?

July 14, 2022 23:54 - 39 minutes - 35.9 MB

VP addresses what to do you if you get an idea from listening to the show, and deconstructs ECHELON-1. Instead of listening we highly recommend you watch the video on YouTube with graphics. This is worth the watch.

5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive?

July 13, 2022 04:59 - 51 minutes - 46.8 MB

How to think about when and how to do RCTs? What are the limitations to observational studies? Smoking. Parachutes. Dostarlimab. Guarantee Time Bias. Confounding. Multiple Hypothesis testing and more

5.02 - Listener Questions - Cancer & Evidence Philosophy - What this Pod Offers

July 11, 2022 01:27 - 46 minutes - 42.6 MB

I make the case why this podcast should be your go to for Med, Onc & Policy. I describe my philosophy of Evidence, Empiricism, and show how this connects to many oncology studies. I answer a bunch of Listener Questions

5.01 - How To Read Randomized Trials In Cancer

July 07, 2022 23:58 - 37 minutes - 34.6 MB

How to read randomized trials in cancer medicine. Phase 2 vs 3, control arm, crossover, post protocol, censoring (the basics), and how law professors and medical professors are different and why it matters.

Lies and Exaggerations about Kids Vaccines < 5 years Old is Bad Public Health

June 22, 2022 05:31 - 19 minutes - 17.4 MB

Lies and Exaggerations about Kids Vaccine I give examples, and show why they are lies

Enact Trial - Enza vs Active Surveillance in Localized Prostate Cancer

June 20, 2022 14:19 - 14 minutes - 13.7 MB

What happens when you treat people with $168,000 a year medicine when most of them will never need treatment, and all of them don't need treatment now

Kids Vaccine For Under 5 years Old

June 18, 2022 22:56 - 42 minutes - 39 MB

I take a deep dive into the data for the mRNA vaccines for kids under 5 years olds

H. Jack West; Lung Cancer; Podcasting; TeleHealth: PACIFIC; ADAURA;CM816: KN189

June 18, 2022 02:54 - 1 hour - 70.6 MB

I sit down with H Jack West. City of Hope. Thoracic Oncology and we have a long discussion about trials; staging; PDL1 thresholds; Driver mutations and post protocol care; ADAURA; Adjuvant; & More

QuANTUM - Quizartinib Front Line - Ethics of Global Trials

June 15, 2022 13:16 - 41 minutes - 38.3 MB

I discuss the timeline of Ratify and Quantum. Was this an ethical trial? Is it sufficient to say a trial is ethical because 50% of participants get something?

4.67 Teclistimab for R/R Multiple Myeloma

June 09, 2022 22:56 - 37 minutes - 34.5 MB

The drug has a high response rate and lots of infections, is it active? Yes; Efficacious? ???? I review ASCO2022 updates

2.66 PD1 Ab for MSI H Stage II/ III Rectal Cancer; A 100% CR rate??

June 08, 2022 14:23 - 24 minutes - 22.2 MB

Are the results from Luis Diaz as good as touted. What trial should they do going forward? A 100% CR rate in Stage II and III rectal cancer??

4.66 PD1 Ab for MSI H Stage II/ III Rectal Cancer; A 100% CR rate??

June 08, 2022 14:23 - 24 minutes - 22.2 MB

Are the results from Luis Diaz as good as touted. What trial should they do going forward? A 100% CR rate in Stage II and III rectal cancer??

4.57 DESTINY BREAST 04 - A complex trial to deconstruct

June 07, 2022 14:25 - 29.5 MB

My take on the standing ovation for DESTINY Breast 04 Traztuzumab Deruxtecan vs. Investigator choice after endocrine therapy and 1 or 2 chemotherapies for HER2 low

4.65 DESTINY BREAST 04 - A complex trial to deconstruct

June 07, 2022 14:25 - 32 minutes - 29.5 MB

My take on the standing ovation for DESTINY Breast 04 Traztuzumab Deruxtecan vs. Investigator choice after endocrine therapy and 1 or 2 chemotherapies for HER2 low

4.64 - DETERMINATION - Should we still use transplant Myeloma?

June 06, 2022 14:52 - 31 minutes - 29.2 MB

I break down Richardson, et al. NEJM DETERMINATION Transplanters are determined to keep going, should they be? Watch the videos b/c I have lots of great visuals My ASCO Coverage continues

4.63 - ASCO22 - DYNAMIC - Can CT DNA Allow us to Give Less Chemo in Stage II Colon Cancer

June 05, 2022 23:14 - 35 minutes - 32.5 MB

The second paper from #ASCO2022 #ASCO22 that I break down This is one of the most technical papers I breakdown on the channel CT DNA used to omit chemo in Stage II colon cancer Read the book Malignant if you learn from this Watch the YouTube Figures https://youtu.be/QxOBIi7I2BU

4.62 - SHINE - Ibrutinib BR vs BR; Limitations to the trial

June 04, 2022 19:33 - 18 minutes - 16.5 MB

Continuous vs. Fixed, 3 vs 2, PFS is the primary endpoint No OS Bad crossover Lots to discuss here I will be covering all the major ASCO papers on @PlenarySession Subscribe to my substack https://vinayprasadmdmph.substack.com/

Guests

Mark Lewis
1 Episode

Twitter Mentions

@brennanspiegel 1 Episode