Editors in Conversation
128 episodes - English - Latest episode: 14 days ago - ★★★★ - 10 ratingsEditors in Conversation is the official podcast of the American Society for Microbiology Journals. Editors in Conversation features discussions between ASM Journals Editors, researchers and clinicians working on the most cutting edge issues in the microbial sciences. Topics include laboratory diagnosis and clinical treatment of infectious diseases, antimicrobial resistance, epidemiology of infections, multidrug-resistant organisms, pharmacology of antimicrobial agents, susceptibility testing, and more.
The podcast is directed to microbiologists, infectious diseases clinicians, pharmacists and basic, clinical and translational researchers interested in the microbial sciences. A particular emphasis is on basic, epidemiological and pharmacological aspects of infectious diseases, including antimicrobial resistance and therapeutics.
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Episodes
Phages as Therapeutic Tools Against Multidrug Resistant Bacteria (AAC ed.)
March 05, 2022 00:40 - 43 minutes - 30 MBBacteriophages are interesting viruses that target bacteria and have been used for therapeutic purposes. Recently, the emergence of antibiotic resistance has spurred a renewed interest in using these viruses or their products as therapeutic tools against recalcitrant human pathogens. AAC has also published a recent manuscript from ARLG to guide the use of phages in clinical practice. We will discuss with experts in the field the state-of-the-art in phage therapy. Objectives: • Understand...
COVID-19 Associated Pulmonary Aspergillosis - The Other CAPA (JCM ed.)
February 18, 2022 12:00 - 46 minutes - 31.9 MBWhen most of us hear the word ‘CAPA’, these days we more than likely immediately start thinking about SARS-CoV-2 variants, trying to remember how important this particular one was in the grand scheme of the COVID-19 pandemic. But, that is not the ‘kappa’ we will be talking about today. Instead, we’ll be discussing the other CAPA, or COVID-19 Associated Pulmonary Aspergillosis, and we will cover a few areas on this topic, including: - Defining what CAPA is and how prevalent it is among ICU ...
WHO, Critical Review, of the Antibacterial Pipeline (AAC ed.)
January 28, 2022 23:16 - 42 minutes - 28.9 MBAAC just published a review from the WHO advisory panel on the antibacterial pipeline analyzing ‘traditional’ and ‘non-traditional’ antibacterial agents and modulators in clinical development current on 30 June 2021 with activity against the WHO priority pathogens, mycobacteria and Clostridioides difficile. Today, we will dissect this important publication Objectives: • Understand the role of the WHO in antimicrobial resistance • Discuss the analysis of the antibacterial pipeline • Del...
WHO Critical Review of the Antibacterial Pipeline (AAC ed.)
January 28, 2022 23:16 - 42 minutes - 28.9 MBAAC just published a review from the WHO advisory panel on the antibacterial pipeline analyzing ‘traditional’ and ‘non-traditional’ antibacterial agents and modulators in clinical development current on 30 June 2021 with activity against the WHO priority pathogens, mycobacteria and Clostridioides difficile. Today, we will dissect this important publication Objectives: • Understand the role of the WHO in antimicrobial resistance • Discuss the analysis of the antibacterial pipeline • Del...
Testing for COVID-19 During the Age of Omicron
January 21, 2022 20:11 - 50 minutes - 34.9 MBIn less than two months since it was discovered, the omicron variant of SARS-CoV-2 has become the dominant variant of the virus, causing an unprecedented rise in the number of cases of COVID-19 in the U.S. and elsewhere. The emergence of this variant has quickly led to some surprising claims about diagnostic testing for omicron and a renewed appreciation of the importance of sequencing the viral genome for typing purposes. We will address several questions about testing for omicron, includin...
Testing for COVID-19 During the Age of Omicron (JCM ed.)
January 21, 2022 20:11 - 50 minutes - 34.9 MBIn less than two months since it was discovered, the omicron variant of SARS-CoV-2 has become the dominant variant of the virus, causing an unprecedented rise in the number of cases of COVID-19 in the U.S. and elsewhere. The emergence of this variant has quickly led to some surprising claims about diagnostic testing for omicron and a renewed appreciation of the importance of sequencing the viral genome for typing purposes. We will address several questions about testing for omicron, includin...
Best Clinical Microbiology Papers of 2021 (JCM ed.)
December 28, 2021 01:07 - 1 hour - 53 MBAs we round out yet another year of this pandemic, clinical microbiologists have not slowed down. We have not slowed down in our response to the pandemic or other day-to-day testing needs, despite the constant reagent backorders and personnel shortages, and equally as important, we have not slowed down in publishing high quality, informative and clinically relevant papers, which have really spanned the gamut of clinical microbiology - from antimicrobial susceptibility testing, to next genera...
Treatment of Acinetobacter spp. Infections (AAC ed.)
December 11, 2021 00:29 - 43 minutes - 30.2 MBInfections caused by carbapenem-resistant Acinetobacter spp. are considered an urgent public health problem. Antibiotic options are scarce but new drugs may be available in the near future. We discuss this important topic with experts in the field. Topics discussed: Acinetobacter as an opportunistic pathogen Therapeutic approaches for Acinetobacter infections The future approach for this MDR organisms. Guests: Dr. Yohei Doi, Professor and Director, Center for Innovative Antimicrobia...
SARS-CoV-2 Sequencing for Clinical Care and Infection Control
November 29, 2021 21:03 - 49 minutes - 34.2 MBIs sequencing the SARS-CoV-2 genome useful for patient care? What about institutional infection control? And if clinical labs decide to perform SARS-CoV-2 sequencing, how should they do it? How should they report the results? And will they get paid? Until recently, sequencing of SARS-CoV-2 genomes has mainly been done in public health or research laboratories. Now, there is increasing interest in sequencing the viral genome in healthcare settings for uses in patient care and infection cont...
SARS-CoV-2 Sequencing for Clinical Care and Infection Control (JCM ed.)
November 29, 2021 21:03 - 49 minutes - 34.2 MBIs sequencing the SARS-CoV-2 genome useful for patient care? What about institutional infection control? And if clinical labs decide to perform SARS-CoV-2 sequencing, how should they do it? How should they report the results? And will they get paid? Until recently, sequencing of SARS-CoV-2 genomes has mainly been done in public health or research laboratories. Now, there is increasing interest in sequencing the viral genome in healthcare settings for uses in patient care and infection cont...
Candida auris at the Intersection of the COVID-19 Pandemic (AAC ed.)
October 29, 2021 11:00 - 46 minutes - 31.7 MBCandida auris is an urgent and high-priority antimicrobial resistant organisms. COVID-19 appears to have increased the identification of this pathogen in vulnerable patients. We discuss with experts the emergence of Candida auris and its relationship with COVID-19. Guests: Dr. Sevtap Arikan-Akdagli, Director, Department of Medical Microbiology, Head of Mycology Laboratory, Hacettepe University Medical School, Ankara, Turkey Dr. Bhavarth Shukla. Assistant Professor of Medicine, Universit...
Candida auris at the Intersection of the COVID-19 Pandemic
October 29, 2021 11:00 - 46 minutes - 31.7 MBCandida auris is an urgent and high-priority antimicrobial resistant organisms. COVID-19 appears to have increased the identification of this pathogen in vulnerable patients. We discuss with experts the emergence of Candida auris and its relationship with COVID-19. Guests: Dr. Sevtap Arikan-Akdagli, Director, Department of Medical Microbiology, Head of Mycology Laboratory, Hacettepe University Medical School, Ankara, Turkey Dr. Bhavarth Shukla. Assistant Professor of Medicine, Universit...
COVID-19 Testing - Schools, False Positives, and In-Person Meetings (JCM ed.)
October 22, 2021 21:19 - 45 minutes - 31.4 MBToday we’re talking about testing in schools for COVID-19, and about recalls of SARS-CoV-2 tests due to false positive results, and, about whether we are ready to go to in-person scientific and medical meetings. Joining me for this roundtable discussion are two frequent guests on the podcast, Dr. Melissa Miller, from UNC School of Medicine, and Dr. Elli Theel, from Mayo Clinic. Links: School Testing for COVID-19. https://www.cp24.com/news/toronto-school-parents-set-up-diy-covid-19-surve...
Testing for COVID-19 Infectivity (JCM ed.)
August 20, 2021 21:19 - 34 minutes - 24.1 MBHow can we determine whether someone who has COVID-19 can transmit the virus to other people? Tests in routine clinical use, such as reverse-transcription polymerase chain reaction and antigen tests, are designed to determine whether SARS-CoV-2 is present or not, but many people have proposed that these tests be used to determine whether a patient is infectious. Furthermore, tests for SARS-CoV-2 that are not routinely used in clinical laboratories, such as viral culture and detection of sub-...
Treatment of VRE Infections (AAC ed.)
July 31, 2021 00:23 - 48 minutes - 33.5 MBEnterococci, particularly vancomycin-resistant isolates tend to affect the most vulnerable and immunocompromised patients and are one of the most difficult bacteria to treat. In absence of robust clinical data, we will discuss therapeutic approaches for these recalcitrant organism.
Advances in Serologic Testing for COVID-19 (JCM ed.)
July 23, 2021 20:24 - 40 minutes - 27.6 MBTests for antibodies, or serological testing, for SARS-CoV-2 have come a long way since the early days of the COVID-19 pandemic. There are now several commercial tests available and some laboratories have developed tests for specific purposes. Tests can determine whether a person has had COVID-19 in the past, or whether someone has had an antibody response to vaccination or even whether someone has antibodies that can neutralize the virus, preventing it from infecting host cells. Guests: ...
Innovative Clinical Trials for COVID-19 (AAC ed.)
July 02, 2021 09:00 - 39 minutes - 27.1 MBDuring the pandemic, the need to develop therapeutic approaches became critical and so the need to study them in a structured way to critically evaluate their effectiveness. Innovative strategies to conduct clinical trials under difficult circumstances were required. We will discuss these strategies with some people who created them! Objectives: • Understand the main challenges to conduct clinical trials in the middle of a pandemic both in the developed and developing world • Discuss st...
Mythbusting in Susceptibility Testing (JCM ed.)
June 25, 2021 22:15 - 36 minutes - 25.3 MBAccurate antibiotic susceptibility testing, or AST, is a key tool in addressing the rise in antibiotic-resistant bacteria. But AST is one of the most complicated and rapidly changing areas in the clinical microbiology, and the resulting confusion can make it difficult for clinical laboratories to keep up with best practices. Dr. Romney Humphries joins to talk about controversies and myths about AST. This episode was recorded with a live, remote audience at the World Microbe Forum. It is br...
Antimalarial Drug-Resistance (AAC ed.)
June 04, 2021 11:00 - 44 minutes - 30.5 MBMalaria continues to be a major “killer’ in the developing world affecting the most vulnerable populations with more than 500,000 deaths per year. Emergence of resistance to antimalarial drugs is major public health issue. In this episode, we will discuss the latest information on this rapidly evolving field with one of the foremost experts in the field. • Review the main factors leading to malaria resistance • Discuss the main genetic mechanism of resistance to antimalarials. • Elaborat...
Staphylococcus argenteus: another coagulase positive Staphylococcus (JCM ed.)
May 28, 2021 11:00 - 28 minutes - 19.8 MBIn addition to Staphylococcus aureus, there are a small number of other coagulase-positive staphylococci. We have become increasingly aware of these due to improvements in identification methods used in clinical laboratories. Staphylococcus argenteus is a coagulase-positive Staphylococcus that, until now, had mainly been detected in Australia, the Pacific Islands and Thailand. It was thought that the species might be geographically restricted, however a paper in the June issue of the Journal...
β-lactam/β-lactamase inhibitor combinations (AAC ed.)
May 07, 2021 17:54 - 46 minutes - 32.3 MBThe development of β-lactam/β-lactamase inhibitors seems to be expanding rapidly and promise to be the best short-term strategy against the most recalcitrant Gram-negative pathogens. In this podcast, we will discuss the current state of the art in this field. Objectives: • Discuss how the discovery of β-lactam/β-lactam inhibitors has evolved • Review the current state-of-the-art of developing of novel β-lactam/β-lactamase inhibitors • Analyze the current and future clinical applicati...
Reconciling Genotypic and Phenotypic Susceptibility Tests (JCM ed.)
April 30, 2021 22:36 - 40 minutes - 28 MBOur options for susceptibility testing have greatly increased in recent years. In addition to classical phenotypic susceptibility testing by disk diffusion and measurement of the minimum inhibitory concentration, genotypic tests are increasingly available. Genotypic tests range from tests for a single organism and one resistance gene to tests for 20 or more organisms and multiple resistance genes. But what should the clinical microbiologist do when the results of phenotypic and genotypic are...
Gaps in Laboratory Diagnosis of Fungal Diseases (JCM ed.)
April 02, 2021 13:00 - 46 minutes - 32.1 MBThe incidence of fungal infections is rising in immunocompromised people, and the morbidity and mortality of these infections are high. Recent threats include multi-drug resistant Candida auris, however antifungal resistance is rising in other species as well, such as Aspergillus fumigatus. But have advances in diagnostic testing kept up with the accelerating threats of fungal infections? Guests: Dr. Esther Babady, Dr. Sean Zhang, Dr. Shawn Lockhart Visit https://jcm.asm.org to read more
Pandemic Built Environment (mSystems ed.)
March 29, 2021 22:54 - 33 minutes - 23.3 MBDuring the pandemic researchers who focus on the microbiology of built environments suddenly found themselves at the center of attention. Understanding how SARS-CoV-2 may be spreading indoors became incredibly important to ensure we can operate indoors in a safe manner. We now know that SARS-CoV-2 transmits through the air in droplets and as particles, and this information has helped us to provide comprehensive advice on how people should manage the indoor environment. Last year my gue...
Developing Non-Traditional Antibiotics (AAC ed.)
March 19, 2021 13:00 - 40 minutes - 27.9 MBDeveloping non-traditional antibiotics promises novel strategies to combat multidrug-resistant organisms but would they work? Are they feasible to develop? Topics discussed: • The notion of non-traditional antibiotics as potential therapeutics against MDR organisms • Increasing our understanding on the clinical efficacy of non-traditional antibiotics • Regulatory pathways for approval of such compounds Guest: Dr. John Rex, Chief Medical Officer, F2G Ltd. | Editor-in-Chief, AMR....
Fermentative Food Microbiome
March 13, 2021 01:48 - 40 minutes - 28.2 MBFermentation is a wonderful thing! Thanks to new technologies and cheaper sequencing we are now able to dig deep into the microbial friends that supply fermentation for so many wonderful foods and drinks. Topics discussed: Why cheese? Other fermented foods that can help shed light on microbial dynamics. Employing metabolomics to explore fermented food mSystems papers that focuses on fermented foods What are the gaps in understanding and what kind of technologies could help to furt...
Fermentative Food Microbiome (mSystems ed.)
March 13, 2021 01:48 - 40 minutes - 28.2 MBFermentation is a wonderful thing! Thanks to new technologies and cheaper sequencing we are now able to dig deep into the microbial friends that supply fermentation for so many wonderful foods and drinks. Topics discussed: Why cheese? Other fermented foods that can help shed light on microbial dynamics. Employing metabolomics to explore fermented food mSystems papers that focuses on fermented foods What are the gaps in understanding and what kind of technologies could help to furt...
Optimizing Blood Cultures with Dr. Eric Ransom and Dr. Valeria Fabre
March 05, 2021 12:00 - 43 minutes - 29.7 MBBlood cultures for bacteria and yeast are among the most clinically important and high-volume tests performed by clinical microbiology labs. Because these cultures are so important to clinical care, we want to make sure that blood cultures are performed as quickly and accurately as possible, and that they are ordered, collected and utilized appropriately. We are going talk about two recent papers. The first is about diagnostic stewardship for improving utilization of blood cultures and the s...
Optimizing Blood Cultures with Dr. Eric Ransom and Dr. Valeria Fabre (JCM ed.)
March 05, 2021 12:00 - 43 minutes - 29.7 MBBlood cultures for bacteria and yeast are among the most clinically important and high-volume tests performed by clinical microbiology labs. Because these cultures are so important to clinical care, we want to make sure that blood cultures are performed as quickly and accurately as possible, and that they are ordered, collected and utilized appropriately. We are going talk about two recent papers. The first is about diagnostic stewardship for improving utilization of blood cultures and the s...
Top Non-COVID-19 AAC Papers of 2020: A discussion with early stage investigators (AAC ed.)
February 26, 2021 13:00 - 1 hour - 43.7 MBWhat influential research outside of COVID-19 was published in AAC in 2020? Objectives: • Discuss pathways of young scientists in antimicrobial resistance • Highlight important papers in AAC in 2020 that were not related to COVID-19 • Stimulate discussion in important topics related to antimicrobial agents I want to welcome my co-host Dr. Maria Fernanda Mojica who is the host of the ASM Journal Club focused on Antimicrobial Agents and Resistance. Dr. Mojica is a Postdoctoral Scholar ...
Top Non-COVID-19 AAC Papers of 2020: A discussion with early stage investigators
February 26, 2021 13:00 - 1 hour - 43.7 MBWhat influential research outside of COVID-19 was published in AAC in 2020? Objectives: • Discuss pathways of young scientists in antimicrobial resistance • Highlight important papers in AAC in 2020 that were not related to COVID-19 • Stimulate discussion in important topics related to antimicrobial agents I want to welcome my co-host Dr. Maria Fernanda Mojica who is the host of the ASM Journal Club focused on Antimicrobial Agents and Resistance. Dr. Mojica is a Postdoctoral Scholar ...
Susceptibility testing for Staphylococci Other Than S. aureus (JCM ed.)
February 12, 2021 08:00 - 38 minutes - 26.8 MBSusceptibility testing for staphylococci other than S. aureus, or SOSA, has become increasingly complicated, as more laboratories use MALDI-TOF to routinely identify these bacteria to the species level. In particular, accurate identification of methicillin resistance has become more complex as the different species are distinguished by the accuracy of different susceptibility testing methods and breakpoints for interpreting MICs and zone sizes. Some of the questions we’ll discuss include: ...
Synthetic Microbiology (mSystems ed.)
January 29, 2021 20:35 - 41 minutes - 28.6 MBWhat is Synthetic Microbiology and why is systems biology central to the development of this exciting scientific discipline? Topics discussed: What is synthetic microbiology? How systems biology and synthetic biology interact What studies should mSystems publish in the field of synthetic microbiology? Guests: Prof. Pam Silver and Prof. Danielle Tullman-Ercek. Visit msystems.asm.org to read articles and/or submit a manuscript. Subscribe to Editors in Conversation (free) on Apple ...
Vaccines for COVID19: A Critical Appraisal with Dr. Carol Baker (AAC ed.)
January 25, 2021 22:46 - 41 minutes - 28.6 MBThe speed of development of vaccines for COVID-19 has been unprecedented, exceeding expectations. A reflection of the process and lessons for the future. A conversation with Dr. Carol Baker. Topics discussed: The vaccine development for COVID-19 and key elements in the initial success Understand the clinical data leading to approval of the vaccines Comment on the future of vaccines with implementation of new technologies Guest: Dr. Carol Baker: Professor of Pediatrics and Universi...
2020: A Bad Year with Great Papers in Clinical Microbiology (JCM ed.)
January 09, 2021 00:12 - 1 hour - 45.4 MB2020 was a great year… for research in clinical microbiology. The COVID-19 pandemic presented unprecedented challenges, including challenges to clinical laboratories. Clinical microbiologists rapidly created a variety of tests for SARS-CoV-2, figured out innovative ways to collect and transport samples for SARS-CoV-2 testing, and also continued their research in areas outside of the pandemic. In this episode of the podcast, three editors of JCM are each going to discuss three of the most imp...
2020: The year of COVID-19 (AAC ed.)
December 18, 2020 19:41 - 44 minutes - 30.6 MBThe emergence COVID-19 changed the entire world, a look back to one of the most difficult years for public health in modern history. Objectives: • Summarize the key events leading to the COVID-19 pandemic • Discuss the missteps and successes on the COVID-19 fight in the US • Comment on the future and what 2021 is likely to bring in relation t the COVID-19 pandemic Guest: • Dr. Jeanne Marrazzo: The C. Glenn Cobbs Professor in Infectious Diseases and Director, Division of Infectious Dis...
COVID-19: Clinical Labs in the Media Spotlight with Dr. Katherine Wu and Dr. Susan Butler-Wu (JCM ed.)
December 11, 2020 19:13 - 43 minutes - 30 MBThe COVID-19 pandemic has brought more media attention to clinical laboratories than at any time in recent history. Today we’ll talk about media coverage of diagnostic testing for COVID-19 with two experts. Some of the questions we’ll discuss include: How has the media coverage of tests for COVID-19 affected the public’s view of these tests? What is the role of social media in talking about testing for COVID-19? How do reporters covering COVID-19 testing work with clinical microbiologis...
COVID-19: Clinical Labs in the Media Spotlight with Dr. Katherine Wu and Dr. Susan Butler-Wu - (JCM ed.)
December 11, 2020 19:13 - 43 minutes - 30 MBThe COVID-19 pandemic has brought more media attention to clinical laboratories than at any time in recent history. Today we’ll talk about media coverage of diagnostic testing for COVID-19 with two experts. Some of the questions we’ll discuss include: How has the media coverage of tests for COVID-19 affected the public’s view of these tests? What is the role of social media in talking about testing for COVID-19? How do reporters covering COVID-19 testing work with clinical microbiologis...
The Antimicrobial Resistance Leadership Group (ARLG) (AAC ed.)
November 30, 2020 22:35 - 46 minutes - 32.2 MBARLG is changing the field of clinical research in antimicrobial resistance. We will talk with the Principal Investigators of the ARLG to discuss their strategy Objectives: • Review the history and accomplishments of ARLG • Discuss the missions of ARLG including training new clinical investigators focused on antibiotic resistance • Comment of the future of ARLG and clinical research on antibiotic resistance Joining me to talk about ARLG are the principal investigators of this ambitio...
The Antimicrobial Resistance Leadership Group (ARLG) - (AAC ed.)
November 30, 2020 22:35 - 46 minutes - 32.2 MBARLG is changing the field of clinical research in antimicrobial resistance. We will talk with the Principal Investigators of the ARLG to discuss their strategy Objectives: • Review the history and accomplishments of ARLG • Discuss the missions of ARLG including training new clinical investigators focused on antibiotic resistance • Comment of the future of ARLG and clinical research on antibiotic resistance Joining me to talk about ARLG are the principal investigators of this ambitio...
Total Laboratory Automation in Clinical Microbiology (JCM ed.)
November 13, 2020 12:00 - 46 minutes - 31.7 MBLet’s talk about total laboratory automation in the clinical microbiology laboratory. Highly automated systems are fairly common in the clinical chemistry and hematology labs, and they are increasingly common in clinical microbiology. Here are some of the questions we’ll answer today. What does total laboratory automation look like in the clinical microbiology laboratory? Are there still manual steps required? In other words, how total is total? What are the benefits of total laboratory a...
The use of remdesivir against SARS-CoV-2 - (AAC ed.)
November 02, 2020 21:01 - 47 minutes - 32.5 MBAAC Launches a new section. New perspectives on antimicrobial agents seeks to provide a clinically-oriented, concise summary supported by emerging clinical trial and/or real-world data. Our first article will be focused on remdesivir Objectives: • Review the rationale for the use of remdesivir against SARS-CoV-2 • Discuss the clinical data supporting the use of remdesivir for COVID-19 • Elaborate on future studies and knowledge gaps for the use of remdesivir New Perspectives on Anti...
The use of remdesivir against SARS-CoV-2 (AAC ed.)
November 02, 2020 21:01 - 47 minutes - 32.5 MBAAC Launches a new section. New perspectives on antimicrobial agents seeks to provide a clinically-oriented, concise summary supported by emerging clinical trial and/or real-world data. Our first article will be focused on remdesivir Objectives: • Review the rationale for the use of remdesivir against SARS-CoV-2 • Discuss the clinical data supporting the use of remdesivir for COVID-19 • Elaborate on future studies and knowledge gaps for the use of remdesivir New Perspectives on Anti...
COVID-19 Diagnostic Testing Redux (JCM ed.)
October 16, 2020 13:00 - 47 minutes - 32.8 MBLaboratory testing for COVID-19, what’s new since we talked about this in August? A lot. Here are some of the questions we’ll talk about. • Do positive antibody tests indicate that people are immune to infection by SARS-CoV-2, the virus that causes COVID-19? • What sample types might replace the dreaded nasopharyneal swab for more comfortable sample collection? • What are the new rapid tests for COVID-19, and how should they be used? Alex is joined by two expert guests to discuss diagn...
Discovering new antibiotics (AAC ed.)
October 05, 2020 18:25 - 38 minutes - 26.7 MBHow are we discovering new antibiotics in the 21st, How is science responding to the antibiotic crisis? Objectives: • Discuss the challenges on discovering new antibiotics in the modern era • Debate the current strategies to find new molecules against the most recalcitrant pathogens • Understand the multiple approaches that could lead to antibiotic development. Visit aac.asm.org to read the latest issue of Antimicrobial Agents and Chemotherapy.
Parasites (JCM ed.)
September 18, 2020 13:00 - 35 minutes - 24.5 MBLet’s talk about parasites. Parasites are shocking. Some of them are large enough to be seen without magnification as they crawl across eyeballs, wriggle under the skin or exit from various orifices of the body. But parasites are fascinating and diverse creatures which live in association with a host, such as a human, and they cause the host harm. Many parasites have complicated life cycles that can involve multiple hosts and different developmental stages of the parasite within each host. ...
The dearth of antibiotic development (AAC Journal)
September 02, 2020 20:57 - 43 minutes - 30.1 MBWhy are we running out of antibiotics? A look at the pharmaceutical development of one of the most life-saving class of drugs. Topics discussed: The reasons behind the stagnant and declining antibiotic development pipeline New initiatives focused on stimulating the antibiotic market Strategies to spur the antibiotic development Guests: Helen Boucher, MD. Professor of Medicine and Chief, Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Editor of AAC Ka...
The dearth of antibiotic development (AAC ed.)
September 02, 2020 20:57 - 43 minutes - 30.1 MBWhy are we running out of antibiotics? A look at the pharmaceutical development of one of the most life-saving class of drugs. Topics discussed: The reasons behind the stagnant and declining antibiotic development pipeline New initiatives focused on stimulating the antibiotic market Strategies to spur the antibiotic development Guests: Helen Boucher, MD. Professor of Medicine and Chief, Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Editor of AAC Ka...
Detection of carbapenemases (JCM Journal)
August 21, 2020 17:32 - 44 minutes - 31 MB• How can the clinical laboratory detect carbapenemases, which are enzyme that can make bacteria resistant to some of the most potent or broad-spectrum antibiotics available? • What is the clinical significance of detecting such an enzyme? Does it affect the care of the patient? • Finally, what practical advice can we give to help labs decide which of the many available tests is the best one for them? The antibiotics we discuss are the “carbapenems,” such as imipenem and meropenem. Thes...
Detection of carbapenemases (JCM Edition)
August 21, 2020 17:32 - 44 minutes - 31 MB• How can the clinical laboratory detect carbapenemases, which are enzyme that can make bacteria resistant to some of the most potent or broad-spectrum antibiotics available? • What is the clinical significance of detecting such an enzyme? Does it affect the care of the patient? • Finally, what practical advice can we give to help labs decide which of the many available tests is the best one for them? The antibiotics we discuss are the “carbapenems,” such as imipenem and meropenem. Thes...