Episode Summary:

Dr. Dan breaks down the known science regarding intermittent fasting.


Topics discussed are as follows:

Introduce intermittent fastingDifferent types of intermittent fastingIntermittent fasting in the scientific literature Potential mode of action of intermittent fastingChallenges and potential issuesKey takeawaysFuture outlook


Episode References:

See here for a review of different types of intermittent fasting: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516560/pdf/nihms663671.pdfCaloric restriction and intermittent fasting cause weight loss to the same degree: https://www.ncbi.nlm.nih.gov/pubmed/29700718Intermittent fasting can reduce body fat in obese subjects: https://www.ncbi.nlm.nih.gov/pubmed/30683819Intermittent fasting can reduce triglyceride and LDL-cholesterol levels: https://www.ncbi.nlm.nih.gov/pubmed/31377182Periodic fasting can increase efficacy of cancer therapies: https://www.ncbi.nlm.nih.gov/pubmed/27557543Beneficial effects of intermittent fasting in asthma: https://www.ncbi.nlm.nih.gov/pubmed/17291990Intermittent fasting and bone health: https://www.ncbi.nlm.nih.gov/pubmed/30903600Intermittent fasting supports healthy gene expression: https://www.ncbi.nlm.nih.gov/pubmed/31356832Athletic performance isn’t increased by intermittent fasting: https://www.ncbi.nlm.nih.gov/pubmed/31283627Intermittent fasting and arthritis: https://www.ncbi.nlm.nih.gov/pubmed/2837251Long term mood is increased with intermittent fasting: https://www.ncbi.nlm.nih.gov/pubmed/17263085Safety precautions in intermittent fasting: https://www.ncbi.nlm.nih.gov/pubmed/29405359