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CEimpact Podcast

304 episodes - English - Latest episode: 6 days ago -

The CEimpact Podcast features three shows; GameChangers, Precept2Practice, and LevelUp. 

The GameChangers podcast, hosted by Geoff Wall, features the latest game-changing  pharmacotherapy advances impacting patient care. New episodes arrive every Monday, and users can earn CPE from each episode. 

The Precept2Practice podcast, hosted by Kathy Scott, features information and resources you can use to precept students and residents. New episodes arrive on the third Wednesday of every month. CEimpact CE Plan members can earn CPE for each episode.

The LevelUp podcast, hosted by Ashlee Klevens Hayes, features conversations surrounding the best practices and products for pharmacy practices and businesses. New episodes with new guests arrive every Wednesday. 

To support our shows, give us a follow and check back each week for our latest episodes. 


Courses Education Science ceimpact podcast precept2practice level up gamechangers pharmacy cme cpe pharmacology ceimpact geoff wall
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Episodes

OTC Birth Control

May 29, 2023 09:00 - 25 minutes - 17.4 MB

OTC Birth Control The proverbial ‘pill’ or hormonal contraception may be available over-the- counter (or at least a progestin-only version) by year’s end. Join guest host,  Jake Galdo, as he discusses improved access to care with Erin Raney as the  FDA debates over-the-counter status for hormonal contraceptives.   The GameChanger Women’s health is a priority area from a public health perspective – the US  has lots of room for improvement. One initiative is to allow a progestin-only  ...

A Pill is OTC?

May 29, 2023 09:00 - 25 minutes - 17.4 MB

The proverbial ‘pill’ or hormonal contraception may be available over-the-counter (or at least a progestin-only version) by year’s end. Join guest host, Jake Galdo, as he discusses improved access to care with Erin Raney as the FDA debates over-the-counter status for hormonal contraceptives. The GameChanger Women’s health is a priority area from a public health perspective – the US has lots of room for improvement. One initiative is to allow a progestin-only hormonal contraceptive have over...

The DOXY-PEP Study

May 22, 2023 09:00 - 32 minutes - 22.3 MB

Sexually transmitted infection (STI) risk in high risk patients is a common problem compounded by antimicrobial resistance. Join host, Geoff Wall, with guest Amanda Bushman, as they discuss a new post-exposure prophylaxis (PEP) therapy for STI prevention   The GameChanger Sexually transmitted infection incidence is higher than most clinicians suspect. Doxycycline may offer effective post-exposure prophylaxis for some HIV positive patients. Host Geoff Wall, PharmD, BCPS, FCCP, BCGP Professor...

Building Confidence in a Clinical Setting

May 17, 2023 09:00 - 37 minutes - 25.5 MB

While we all know students who may exhibit more confidence that they have the right to based on their actual knowledge and experience, more often as preceptors we have students who demonstrate a lack of confidence that gets in the way of their learning. It is easy to make assumptions about why a student demonstrates a lack of confidence, but often we have missed the mark. By understanding the root cause of waning confidence in a pharmacy learner, we can develop strategies to increase confide...

Personalized Treatment for Hypertension?

May 15, 2023 09:00 - 26 minutes - 18.1 MB

About 50% of Americans have hypertension, yet WHICH is a preferred anti-hypertensive strategy is a random process. And pharmacogenomics may not be needed. Join host, Geoff Wall, as he evaluates a recent study evaluating the role of personalized medication selection for persons with hypertension.   The GameChanger Although no genetic markers exist to determine optimal hypertensive pharmacotherapy, initial and secondary hypertensive therapy does impact outcomes. A personalized approach does pr...

The Novel RSV Vaccine: Part 2

May 08, 2023 09:00 - 31 minutes - 21.9 MB

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 2 of a two-part series examining new research on the proposed RSV vaccine.   The GameChanger RSV, COVID-19, and influenza are major disease burdens on children and older adults. Fortunately, COVID-19 and influenza have widely available vaccines – and maybe soon for ...

The Novel RSV Vaccine: Part 1

May 01, 2023 09:00 - 29 minutes - 20.2 MB

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 1 of a two-part series examining new research on the proposed RSV vaccine. The GameChanger RSV, COVID-19, and influenza are major disease burdens on children and older adults. Fortunately, COVID-19 and influenza have widely available vaccines – and maybe soon for R...

Hydrocortisone for Severe CAP

April 24, 2023 09:00 - 26 minutes - 18.3 MB

Community Acquired Pneumonia (CAP) has a high mortality rate. A new study evaluates the use of hydrocortisone for severe CAP in the ICU setting. Join host, Geoff Wall, as he evaluates if the evidence stacks up. The GameChanger The use of steroids to treat severe pneumonia has waxed and waned for many years with insufficient evidence. A recent study found steroids improved a number of outcomes, including mortality. Show Segments 00:00 - Introductions 01:19 - Past Studies on CAP Treatment 03...

Share the Load! Co-Precepting for Student Success

April 19, 2023 09:00 - 32 minutes - 22.6 MB

Co-precepting can help with workload while providing a diverse experience for learners, but it is not without its challenges. Listen in to weigh the pros and cons while gathering some strategies to ensure success if you plan to consider, or are currently, co-precepting with a colleague. Kate Newman is the Director of Experiential Education at Southern Illinois University Edwardsville School of Pharmacy. She’s been seeing more co-precepting arrangements with her affiliate experiential educat...

Deprescribing Medications in Post-Acute Care

April 17, 2023 09:00 - 32 minutes - 22.1 MB

Several studies have found the improved outcomes and quality of life through deprescribing. However, it rarely happens. Join host, Geoff Wall, with guest, Kristin Meyer, as they evaluate a new studying looking at pharmacist-provided describing services during transition of care. The GameChanger Older patients are on numerous medications often with limited therapeutic benefit and high risk of adverse events. Many of these medications can be discontinued with no change in outcomes. Pharmacist...

DVT prophylaxis in the ICU

April 10, 2023 09:00 - 26 minutes - 18.4 MB

ICU patients are at high risk for venous thromboembolism, and the majority of patients require prophylaxis. The challenging therapy is thrombocytopenia. Join host Geoff Wall, as he evaluates the results of a new study evaluating the clinical thresholds for chemical prophylaxis. The GameChanger The majority of ICU patients eligible for VTE prophylaxis do not receive it. Different clinicians use different thresholds to initiate or stop prophylaxis. The database study discussed provides a pote...

The Updated AAAAI Guidelines on Drug Allergies

April 03, 2023 09:00 - 31 minutes - 21.7 MB

The Updated AAAAI Guidelines on Drug Allergies Drug allergies are a common challenge for all prescribers, patients, and pharmacies. They are associated with increased costs, adverse effects, and extended hospitalizations. Join host Geoff Wall as he reviews the newly released AAAI guidelines on drug allergies. The GameChanger Over 90% of patients claiming a penicillin allergy are not allergic. Sulfamethoxazole desensitization is largely not needed. A thorough evaluation of patient allergies...

Do Masks Work or Not?

March 27, 2023 09:00 - 29 minutes - 20.3 MB

Although the numbers may be low, COVID-19 and other illnesses remain a significant threat to patients. The role of masks in preventing SARS-CoV-2 spread has been politicized since the beginning. A new meta-analysis purports to answer the question of mask effectiveness. Join host Geoff Wall, with guest Jake Galdo, as they deep dive into the article and evaluate the science. The GameChanger A new meta-analysis suggests that mask mandates do not affect the prevention and spread of COVID-19. Ho...

Pharmacogenomics for Adverse Drug Reactions

March 20, 2023 09:00 - 31 minutes - 21.5 MB

Pharmacogenomics have long held the promise of using personalized information for drug selection to maximize efficacy and minimize adverse reactions. A new study evaluates the routine use of pharmacogenomic testing to improve safety in a wide range of medications. Join host, Geoff Wall, as he evaluates personalized medicine. The GameChanger Most studies using routine pharmacogenomic testing in clinical practice have not been significant. However, a new study found a 12 panel pharmacogenomic...

What Do Students Say?

March 15, 2023 09:00 - 36 minutes - 24.8 MB

Pharmacy learners - IPPE, APPE, Residents - may not always be forthcoming with honest feedback. But they know what they appreciate (or don't) in a learning experience. As a preceptor, your approach to teaching has a huge impact on student learning. We asked two 4th year pharmacy learners to share what matters most to them in a preceptor. Their answers may surprise you! Listen in to learn what students most value in their learning experiences and gather some strategies you can use to enhance...

Fluid Administration in Septic Shock

March 13, 2023 09:00 - 35 minutes - 24.1 MB

For the past two decades, large amounts of isotonic fluids have been the first step in treating septic shock despite adverse events of fluid overload, coagulopathy, and pulmonary edema. A new NIH study evaluates this strategy. Join host, Geoff Wall, with guest, Matt Trump, DO, as they evaluate initial septic shock management. The GameChanger Liberal fluid management (30 mL/Kg) in the early phase of septic shock may not result in lower mortality than a more restrictive strategy. However, vas...

The 2023 ADA Diabetes Guidelines

March 06, 2023 10:00 - 28 minutes - 19.5 MB

Every January, the American Diabetes Association publishes the Standards of Care in Diabetes. The guidelines are a living document and change throughout the year; however, the January update is the seminal changes for the entire document. Join host, Geoff Wall, with guest, Jake Galdo, as they discuss what’s new and great in the guidelines. The GameChanger In addition to medication recommendations, the guidelines now emphasize the role of Community Health Workers in the management of health-...

The Gold Standard Loop Diuretic for HFrEF

February 27, 2023 10:00 - 22 minutes - 15.3 MB

Furosemide is the most prescribed loop diuretic for heart failure; however, furosemide’s pharmacokinetic parameters are less than ideal compared to other loop diuretics. Join host, Geoff Wall, as he evaluates the first randomized controlled trial comparing loop diuretics in heart failure. The GameChanger Torsemide has potential pharmacokinetic advantages compared to furosemide in the treatment of heart failure. However, a recent study did not find meaningful differences in clinical outcomes...

Pediatric Vaccinations

February 20, 2023 10:00 - 27 minutes - 18.7 MB

Routine pediatric vaccines are declining and 97% of pediatric influenza deaths are in unvaccinated children. Join host Geoff Wall, with guest Jake Galdo, as they discuss what the heck is happening with pediatric vaccines and how the healthcare community can step up. The GameChanger The Advisory Committee on Immunization Practices provides recommendations for routine vaccines for all persons. Pharmacists are an integral part of ensuring adherence to vaccine schedules. Differences in state sc...

What Can You Learn From Your Learners?

February 15, 2023 10:00 - 27 minutes - 18.9 MB

As preceptors, sometimes one of the hardest things we do is give feedback. What about when we receive it? Listen to learn how to engage students in ways that result in meaningful feedback you can use to improve your teaching. You're putting in the work. Why not make it as impactful as possible for your learners? This week I’m speaking with Nick Cox – a faculty member and preceptor in an ambulatory care setting – on the topic of feedback – how to invite it, how to prepare to receive it, and ...

Using Feedback to Your Advantage

February 15, 2023 10:00 - 27 minutes - 18.9 MB

As preceptors, sometimes one of the hardest things we do is give feedback. What about when we receive it? Listen to learn how to engage students in ways that result in meaningful feedback you can use to improve your teaching. You're putting in the work. Why not make it as impactful as possible for your learners? This week I’m speaking with Nick Cox – a faculty member and preceptor in an ambulatory care setting – on the topic of feedback – how to invite it, how to prepare to receive it, and ...

Thrombolytic Use in Persons with Stroke and Direct Oral Anticoagulants

February 13, 2023 05:00 - 27 minutes - 19 MB

Patient use of any anticoagulation during an acute stroke is a contraindication for the use of thrombolytics or clot busters. Recent meta-analyses and animal studies raise the question of this contraindication. Join guest, Geoff Wall, as he examines the data on Direct Oral Anticoagulants (DOACs) and thrombolytics. The GameChanger DOACs have a significantly smaller intracranial hemorrhage (ICH) risk compared to warfarin and this benefit may translate to risk of bleed with thrombolytics. A ne...

A Guideline Review for Osteoporosis (GC 406)

February 06, 2023 05:00 - 27 minutes - 19.1 MB

Osteoporosis may be a forgotten disease – common but rarely treated. The 2023 guidelines are not here. Join host, Geoff Wall, as he reviews the new treatment recommendations and how we can optimize pharmacotherapy for all persons with osteoporosis. The GameChanger Osteoporosis is common and routine screenings should be implemented. Bisphosphonates are still the drug of choice, but treatment for persons over 65 should be made on a case-by-case basis. Show Segments 00:00 - Introduction 00:25...

A Guideline Review for Osteoporosis

February 06, 2023 05:00 - 27 minutes - 19.1 MB

Osteoporosis may be a forgotten disease – common but rarely treated. The 2023 guidelines are not here. Join host, Geoff Wall, as he reviews the new treatment recommendations and how we can optimize pharmacotherapy for all persons with osteoporosis. The GameChanger Osteoporosis is common and routine screenings should be implemented. Bisphosphonates are still the drug of choice, but treatment for persons over 65 should be made on a case-by-case basis. Show Segments 00:00 - Introduction 00:25...

The DCP Study: HCTZ vs Chlorthalidone

January 30, 2023 05:00 - 22 minutes - 15.3 MB

Hydrochlorothiazide is the go-to thiazide for hypertension control despite better data for chlorthalidone. Join host Geoff Wall as he evaluates the new randomized controlled study to determine what is the best thiazide. The GameChanger Several pharmacologic differences exist between hydrochlorothiazide and chlorthalidone. The new DCP Study did not find any differences in cardiovascular outcomes. Show Segments 00:00 - Introductions 02:20 - History of HCTZ vs Chlorthalidone 05:26 - The Diure...

Zinc for the Treatment of COVID-19

January 23, 2023 10:00 - 22 minutes - 15.3 MB

Results from early COVID-19 studies are still emerging. Some micronutrients, such as zinc, have been shown to decrease the severity of viral infections yet human data is sparse. Join host, Geoff Wall, as he evaluates a new study looking at the proposed benefit of zinc in COVID-19 infections. The GameChanger Zinc has several antiviral properties. A recent trial showed a decreased risk of ICU admission – however, has numerous exclusion criteria impacting the external validity. Show Segments ...

Asking the Right Questions of Your Students and Residents

January 18, 2023 05:00 - 42 minutes - 29 MB

Sometimes teaching isn't "telling" but "asking" - asking questions that encourage students and residents to problem-solve in a stepwise manner. Listen in as we discuss a teaching strategy that builds confidence and encourages curiosity in your learners. We’ve all heard students and residents complain about ‘pimping’ from preceptors during rotations or during their residency experience. Pimping has given a bad name to what can truly be a very effective teaching strategy when done right – Soc...

A First Treatment for Celiac Disease?

January 16, 2023 10:00 - 22 minutes - 15.2 MB

Celiac disease is of the most common auto-immune diseases in the world. The only current treatment is maintaining a strict gluten-free diet. Join host, Geoff Wall, as he discusses the results of a phase 2 study investigating a novel pharmacologic treatment of Celiac disease. The GameChanger Celiac disease is common and has a myriad of symptoms. A new drug may offer a way for patients with Celiac disease to eat gluten without issue. Show Segments 00:00 - Introductions 00:50 - The Effects o...

Diabetes Pharmacotherapy Update

January 09, 2023 10:00 - 28 minutes - 19.5 MB

The American Diabetes Association Standards of Care in Diabetes are a “living” guideline – the recommendations are updated throughout the year and major revisions occur in January. In this episode, guest host, Jake Galdo, is joined by Susan Cornell as they evaluate new pharmacotherapy recommendations in the ADA Standards of Care. The GameChanger Treatment recommendations for diabetes are no longer metformin plus. Now initial, and augmented therapy, is driven by comorbid conditions. Show Se...

Cardiovascular Safety of ADHD Medications

January 02, 2023 10:00 - 20 minutes - 14.2 MB

Stimulant medications, like methylphenidate and amphetamines, have adverse cardiovascular effects, like elevated blood pressure, increasing the risk of cardiovascular events. Join host Geoff Wall as he reviews a new meta-analysis trying to quantify the risk of ADHD medications on cardiovascular outcomes. The GameChanger A large meta-analysis did not find an association between medications for ADHD and cardiovascular disease. Several limitations may interfere with the applicability of these ...

The 2023 GOLD Guidelines

December 26, 2022 10:00 - 23 minutes - 16.4 MB

COPD is a common and complex disease for both inpatient and outpatient providers. GOLD guidelines provide diagnosis and treatment recommendations for COPD and were recently updated. Join host Geoff Wall as he breaks down the salient recommendations in the 2023 GOLD guidelines. The GameChanger A new severity scoring system for COPD exists – category E. Additionally, inhaled corticosteroids may play a larger role in the pharmacotherapy of COPD. Show Segments 00:00 - Introductions 01:40 - Ba...

Help the Hurt - Support Students and Residents Who Experience Microgressions

December 21, 2022 10:00 - 19 minutes - 13.3 MB

We’ve heard a lot about microaggressions in the past couple of years. A microaggression can include verbal, behavioral, or environmental aggressions that negatively communicate about race, culture, or gender. They can be intentional or unintentional but can negatively impact healthcare interactions – whether those involve students, residents, patients, or all of the above. In this episode, speaking with Anisa Hansen, a clinical pharmacist who leads diversity, equity, and inclusion initiativ...

Help the Hurt - Support Students and Residents Who Experience

December 21, 2022 10:00 - 19 minutes - 13.3 MB

We’ve heard a lot about microaggressions in the past couple of years. A microaggression can include verbal, behavioral, or environmental aggressions that negatively communicate about race, culture, or gender. They can be intentional or unintentional but can negatively impact healthcare interactions – whether those involve students, residents, patients, or all of the above. In this episode, speaking with Anisa Hansen, a clinical pharmacist who leads diversity, equity, and inclusion initiativ...

Perioperative Gabapentin

December 19, 2022 10:00 - 17 minutes - 12.2 MB

Gabapentin is often used in a multi-model pain management strategy in both peri- and post-operative setting. Little data exists looking at the adverse effects of this practice. Join host Geoff Wall, as he reviews data from a new study looking at this question. The GameChanger Gabapentin’s data is sparse for use in postoperative pain; however, new data suggest use after orthopedic surgery is associated with poor outcomes. Show Segments 00:00 - Introductions 00:58 - The Current Use of Gabap...

Fluid Resuscitation in Pancreatitis

December 12, 2022 10:00 - 16 minutes - 11.4 MB

The standard of care for pancreatitis has been aggressive (liters) of intravenous fluids. New data suggests that this level of fluid resuscitation may not be needed – and possibly harmful. Join host Geoff Wall as he evaluates the role of fluids in pancreatitis treatment. The GameChanger In patients with mild disease, moderate fluid resuscitation is safer than aggressive fluid use. Show Segments 00:00 - Introduction 01:17 - Current Standard of Care 04:37 - The WATERFALL Study 10:20 - GameC...

Treatment of Acute Ethanol Withdrawal

December 05, 2022 10:00 - 25 minutes - 17.2 MB

A recent study showed that ethanol abuse is a leading cause of death in young adults in the US and that rates of alcoholism have increased. Join host Geoff Wall as he reviews the treatment of ethanol withdrawal. The GameChanger Ethanol abuse is a leading cause of death in young adults. Fortunately, multiple therapies exist to treat hospitalized patients with acute ethanol withdrawal.  Show Segments 00:00 - Introductions 01:44 - Alcohol Abuse and Mortality in the United States 03:38 - GameC...

A Review of the AGA Obesity Guidelines

November 28, 2022 10:00 - 26 minutes - 18.5 MB

Obesity is still at epidemic levels in the United States. More and more medications are coming to market to help with weight loss. The American Gastroenterological Association (AGA) just released guidelines for evidence-based care for persons with obesity. The GameChanger Guidelines are now available for the treatment of obesity. The evidence-based recommendations will help providers determine appropriate therapy for persons with obesity. Show Segments 00:00 - Introduction 01:16 - The Obes...

Food Insecurity and Cardiovascular Outcomes

November 21, 2022 10:00 - 27 minutes - 18.9 MB

Health Equity is achieved when every person has the opportunity to attain their full health potential and no one is disadvantaged. Oftentimes, this is evaluated and addressed through resolving social determinants of health. A recent study evaluated the impact of food insecurity on cardiovascular outcomes. Join host, Geoff Wall, as he discusses how healthcare teams can address food insecurity with guest Jake Galdo. The GameChanger Increased screening, identification, and referrals are needed...

Incorporating Risk Management Principles into Your Teaching

November 16, 2022 10:00 - 46 minutes - 32 MB

Whose job is it to teach risk management principles to pharmacy learners? Sure – they have to take a law course as part of their curricular requirements, but how much does that mean to them until they are in real life situations as part of their IPPEs, APPEs, or residency? As preceptors, it’s important that we not only recognize and manage the legal risks of welcoming pharmacy learners within our pharmacy practice but also that we are prepared to teach practical concepts such as risk managem...

The Role of Dapagliflozin in Heart Failure

November 14, 2022 10:00 - 26 minutes - 18.5 MB

Various SGLT-2s have been shown to improve cardiovascular outcomes in the presence and absence of diabetes. A recent study evaluated the effect of dapagliflozin in mildly reduced or preserved ejection fraction. Join host, Geoff Wall, as he discusses how SGLT-2s may be a real GameChanger in heart failure with expert, Troy Lynn Lewis. The GameChanger The data showcasing the benefits of SGLT-2s in patients with heart failure with or without diabetes continues to grow. Dapagliflozin may be anot...

An Update on Glucagon

November 07, 2022 10:00 - 25 minutes - 17.8 MB

Less than ten percent of people filled a glucagon prescription after a hospitalization due to hypoglycemia. In the past few years, a slew of new glucagon products have come to market. Join host, Geoff Wall, as he discusses how to optimize glucagon therapy with diabetes expert, Jamie Pitlick. The GameChanger Despite glucagon products being proven safe and effective, they are severely under-prescribed and underutilized.  Patients that are at risk for level 2 or 3 hypoglycemia should be prescr...

The GRADE Studies for Type 2 Diabetes

October 31, 2022 09:00 - 34 minutes - 23.4 MB

The GRADE studies evaluated the pharmacotherapy of diabetes after initiation of metformin – for both micro- and macrovascular outcomes. Join host, Geoff Wall, and guest Jake Galdo as they examine these studies to determine if they are GameChangers in diabetes management. The GameChanger Insulin glargine and liraglutide had the biggest decrease in A1c; however, many patients still did not reach goal targets. Minor differences in microvascular and macrovascular outcomes were observed. Show S...

Aspirin De-Prescribing in Patients Taking Anticoagulants

October 24, 2022 09:00 - 20 minutes - 14.1 MB

The role of anticoagulant therapy (warfarin) with antiplatelet therapy (aspirin) is a balance of risk versus benefit. However, reducing risk by de-prescribing is often avoided due to hypothetical efficacy reduction. Join host, Geoff Wall, as he evaluates de-prescribing aspirin in patients taking anticoagulants. The GameChanger Anticoagulant therapy provides as good or better protection against vascular outcomes as aspirin – creating duplication of therapy. The increased risk of bleeds may n...

Integrating Students to Enhance Pharmacy Services

October 19, 2022 09:00 - 40 minutes - 28 MB

So often, we can fall into the trap of viewing our time with experiential learners as a burden – something that takes time and energy that we feel we don’t have in a busy practice. How can you operationalize and optimize student contribution on-site, build trust among all parties, and overcome challenges and barriers that come along with experiential learning? Tune in to find out how one busy community pharmacist engaged his students to provide an exceptional learning experience that has enh...

Acetazolamide for Diuresis in Hospitalized Heart Failure Patients

October 17, 2022 09:00 - 26 minutes - 18.3 MB

Studies suggest that patients admitted to the hospital with heart failure are inadequately diuresed before discharge. Join host, Geoff Wall, as he reviews the data on acetazolamide for diuresis in heart failure. The GameChanger Augmentation of loop diuretics with acetazolamide significantly increases diuresis in persons with heart failure. Geoff produces music under the name, Prophets of Jupiter. This is the song he mentions at the end of the episode - Time to Dance - Lola K Remix. The CO...

Restrictive versus Standard Fluids in Septic Shock

October 10, 2022 09:00 - 25 minutes - 17.4 MB

The current standard of care is to provide a bolus of 30 mL per kg of isotonic fluid for patients with septic shock. Recent retrospective studies question this practice. Join host, Geoff Wall, as he reviewed a NEJM article on the role of fluids in septic shock. The GameChanger Large boluses of fluid during septic shock may have unintended adverse events. Some data show that an approach with restrictive fluids may have no difference in death or adverse outcomes. The COVID-19 pandemic is sti...

The COVID-19 Reality: An Update

October 03, 2022 09:00 - 29 minutes - 20.5 MB

Get FREE CE for this episode by downloading the CEimpact App (details in the FREE CE section). The current reality of COVID-19 is reviewed in this episode by Dr. Katelyn Jetelina. Dr. Jetelina is an epidemiologist and author of the wildly popular Newsletter, Your Local Epidemiologist, available via Substack.    We are losing ~400 Americans a day. During the first week of September, we lost 2,299 people. In August 2022 alone, we lost 15,284 Americans to COVID-19. This means COVID-19 remains...

A Treatment for Monkeypox?

September 26, 2022 09:00 - 21 minutes - 15 MB

Monkeypox is the newest worldwide pandemic and closely mirrors both COVID-19 and HIV pandemics. A large difference is theoretical vaccines and treatments for monkeypox already exist. In this episode of GameChangers, host Geoff Wall, evaluates tecovirimat, a potential monkeypox treatment and the regulations that made it possible. The GameChanger Little to no randomized controlled data exist on tecovirimat’s safety and efficacy in monkeypox. A recent case series helps establish the safety of...

Pharmacogenomic Selection of Antidepressants

September 19, 2022 09:00 - 27 minutes - 19 MB

Pharmacogenomic testing has been widely available for over a decade to help guide pharmacotherapy including antidepressant selection when treating major depressive disorder. Yet, the data hasn’t substantiated improved safety or efficacy. Host Geoff Wall is joined by Sarah Grady, PharmD to evaluate the PRIME study looking at the role of pharmacogenomic testing in depression. The GameChanger Pharmacogenomic testing may help decrease adverse effects at 12 weeks, but not 24 weeks. However, th...

Identifying and Addressing Bias in Pharmacy Learners

September 14, 2022 09:00 - 22 minutes - 15.7 MB

Studies have connected racial and cultural bias in students and how they approach patient cases in their respective PharmD curriculum. How can preceptors identify and address potential bias in pharmacy learners to help ensure healthcare equity?   Host Kathy Schott, PhD CEimpact   Guest LaQuoia Johnson, PharmD, BCPS, DPLA Pharmacy Consultant Growing Through It [email protected] More about Dr. LaQuoia Johnson  Dr. LaQuoia Johnson is the author of How Rxacism Manifests: Inside the Smal...

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