Rest between sets vs. rest between reps... Will the result be different?

What if you kept the resistance, volume, and overall rest time the same, but altered how the rest time is taken, would you expect a different result after 10 weeks of training? I love this topic because it shows a flaw when only using volume (reps x sets x resistance) to track training over time. Volume can be the same on paper, but what will not be presented are critical variables such as time under tension, velocity, and intention to move a resistance quickly. This is the basis of this episode, where fatigue comes into play and slows down repetition speed (thereby increasing time under tension) or providing rest intervals after each rep to maintain high repetition velocity (but reducing time under tension). Do you think each tactic will improve overall strength the same? Will one have enhanced hypertrophy over the other? Better tune in and find out!

Article of reference:
Davies, T.B., et. al. Effect of set-structure on upper-body muscular hypertrophy and performance in recreationally trained males and female. Journal of Strength & Conditioning Research 36(8)/2176-2185