AMiNDR: A Month in Neurodegenerative Disease Research
350 episodes - English - Latest episode: 20 days ago -This is a podcast made by scientists for scientists, to help you save time so you can conduct better research. For a given month, we sort the abstracts of the latest primary research articles on Alzheimer's disease into separate categories. We then summarize them for you to enjoy on the bus, on your jog, or in the lab. We hope you find our podcast useful and accessible.
Homepage Google Podcasts Overcast Castro Pocket Casts RSS feed
Episodes
95 - Detecting Amyloid & Tau in Alzheimer's Disease: September 2020
January 18, 2021 01:30 - 30 minutes - 28.2 MBIn this half-hour episode, Judy goes through September 2020 papers that look at diagnosing or characterizing Alzheimer's disease based on the detection of the proteins amyloid and tau in the brain and other structures. Topics include conventional and novel neuroimaging techniques, deep learning methods and retinal amyloid-beta. Tune in to find out more! Sections in this episode: PET Deep Learning Methods 1:06 Standardized Uptake Value Ratios 4:00 Mild Cognitive Impairmen...
94 - Brain Imaging of Structural Changes & Connectivity in Alzheimer's Disease, Part 1: September 2020
January 15, 2021 05:00 - 24 minutes - 22.3 MBBhumika updates you on the latest papers on brain imaging of structural changes and connectivity in AD! This includes MRI and PET imaging to characterize or diagnosis this disease, as well as new machine learning technology, and more! Enjoy, and look out for part 2 soon! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiND...
93 - Inflammation, Glial Cells & TREM2 in Alzheimer's Disease, Part 2: September 2020
January 15, 2021 02:00 - 26 minutes - 24.6 MBCourtney is back with Part 2 of Inflammation, Glial Cells and TREM2 papers published in September of 2020! If you haven't already, check out Part 1 in episode #91. In this exciting sequel, she discusses methods to study inflammation, astrocytes in inflammation and peripheral immunity. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting...
92 - Fluid Biomarkers for Alzheimer's Disease Part 2: September 2020
January 13, 2021 01:00 - 46 minutes - 42.7 MBElyn is back with more on fluid biomarkers for Alzheimer’s Disease from September 2020 papers. Here, she covers new candidate biomarkers including panels of lipids, soluble TREM2, and methylation sites on known risk genes. She also dives into insight into APOE4 mechanisms revealed by biomarkers, the stark overlap between vascular dementia and Alzheimer’s disease, and much more. This is a long one, but definitely worth a listen! Sections in this episode: Lipids - 6 papers - 3:22 ...
91 - Inflammation, Glial Cells & TREM2 in Alzheimer's Disease, Part 1: September 2020
January 11, 2021 06:35 - 32 minutes - 30 MBCourtney updates you on all the new publications from September 2020 about inflammation, glial cells, and TREM2, in the context of Alzheimer's disease. There were a lot of papers on these topics, so we split it up into 2 episodes. Stay tuned for part 2 coming soon! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiNDR_podc...
90 - New Genetic Variants in Alzheimer's Disease: September 2020
January 08, 2021 05:00 - 23 minutes - 21.6 MBIs the ever-expanding genetic landscape of Alzheimer’s disease overwhelming for you? Joseph will help you catch up on all the literature about new genes or variants linked to Alzheimer’s Disease in September 2020. Sections in this episode: Novel Gene Discovery - 1:08 New Variant Discovery - 10:24 Testing Associations in Novel Genes - 13:50 Miscellaneous - 18:33 ------------------------------------------------------------------ To receive the list of papers covered, please ...
89 - Treatments targeting amyloid-beta-mediated toxicity in Alzheimer's Disease: September 2020
January 06, 2021 05:55 - 13 minutes - 12 MBIn this episode, Marcia updates you on 8 papers from September 2020 on the development of treatments that target amyloid-beta mediated toxicity to treat Alzheimer's disease. Tune in to hear more! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiNDR_podcast ---------------------------------------------------------------...
88 - Non-Pharmacological Treatment Approaches for Alzheimer's Disease: September 2020
January 06, 2021 02:53 - 38 minutes - 34.9 MBIn today’s episode, you’ll hear about the latest developments in preventing or treating AD using non-pharmacological approaches, such as cognitive interventions, stimulation techniques, and exercise. Naila covers clinical trials in humans and mechanistic studies in animal models, all in 19 papers. Enjoy! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ----...
87 - Cognitive & Behavioural Changes in Alzheimer's Disease: September 2020
January 04, 2021 03:00 - 31 minutes - 29.1 MBInterested in the behavioural aspects of AD such as changes to cognition, emotion, sleep, sensory and verbal abilities, and learning and memory? Look no further. Anusha will guide you through the literature that was published on these topics in September (2020) to help you start the new year off on the right foot. Sections in this episode: 1.47 Cognition/Emotional Processing/Depression 10.35 Sleep 17.24 Verbal/Audition/Olfaction 25.04 Learning and Memory -----------------...
86 - Treatments Targeting the Immune System & Glia in Alzheimer's Disease: September 2020
January 03, 2021 21:00 - 20 minutes - 18.3 MBHappy New Year from the AMiNDR team! In our first episode of 2021, Abdullah presents on the modulation of inflammatory response in AD, with a big emphasis on microglia, the forgotten heroes in his mind, they clean, repair and protect your brain. Hopefully by the end of the episode you’ll know more about why changing their behaviour could be the treatment we are looking for. Sections in this episode: Targeting NLRP3: 2:00 Favouring M2 over M1 for microglia: 5:57 Other: 11:00 ...
85 - Fluid Biomarkers Part 1: September 2020
December 23, 2020 04:00 - 30 minutes - 27.7 MBInterested in the mission to accurately diagnose Alzheimer’s disease with a blood test? This episode is perfect for you. In this two-part episode on Fluid Biomarkers in AD from September 2020 papers, Elyn explains the ATN framework for AD diagnosis, and covers papers focused on fluid biomarkers relating to amyloid, tau, and neurodegeneration. She also touches on a few new methods for biomarkers researchers. Tune in to hear about how storage conditions can affect measurements, how assay platf...
85 - Fluid Biomarkers for Alzheimer's Disease Part 1: September 2020
December 23, 2020 04:00 - 30 minutes - 27.7 MBInterested in the mission to accurately diagnose Alzheimer’s disease with a blood test? This episode is perfect for you. In this two-part episode on Fluid Biomarkers in AD from September 2020 papers, Elyn explains the ATN framework for AD diagnosis, and covers papers focused on fluid biomarkers relating to amyloid, tau, and neurodegeneration. She also touches on a few new methods for biomarkers researchers. Tune in to hear about how storage conditions can affect measurements, how assay platf...
84 - APP processing and amyloid-beta aggregation in Alzheimer's Disease: September 2020
December 22, 2020 20:00 - 29 minutes - 26.9 MBIn this episode, Jacques will tell you about new peer-reviewed publications from September 2020 on mechanisms of APP processing and protein aggregation in the context of Alzheimer's disease. This includes aggregation of amyloid-beta as well as other proteins such as tau and alpha-synuclein. Enjoy the episode! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ...
83 - Treatments targeting amyloid-beta aggregation and more in Alzheimer's Disease: September 2020
December 21, 2020 07:00 - 27 minutes - 11.1 MBIn this episode, Marcia covers papers published in September 2020 that focus on the latest in novel drug development in AD. We especially talk about papers targeting amyloid-beta aggregation, BACE-1 inhibitors, gamma-secretase, immunotherapy for AD and more! Tune in to learn more. 5:46 - BACE-1 9:09 - Gamma secretase 11:12 - More papers on amyloid-beta aggregation ------------------------------------------------------------------ To receive the list of papers covered, please fill this ...
82 - Metabolism & Mitochondrial Dysfunction in Alzheimer's Disease: September 2020
December 21, 2020 05:23 - 26 minutes - 24.2 MBIs your research on diet and nutrition and Alzheimer’s disease? Or maybe you are diving deeper into the role of carbs and fat metabolism, and are interested in mitochondrial function in neurodegenerative diseases? Then stay here! Sarah covers 13 papers from our September 2020 harvest with topics ranging from the ketogenic diet to the lipidome. List of sections: Diet and nutrition: 2.18 Carbohydrate and lipid metabolism: 5.44 Protective aspects of metabolism: 14.23 Mechanisms of mit...
81 - Cerebrovascular changes in Alzheimer's Disease Part 1: September 2020
December 20, 2020 20:55 - 24 minutes - 22.9 MBElyn is back to cover the latest findings relating to the cerebrovasculature in Alzheimer disease! In this two part episode covering papers from September 2020, you’ll hear about how aging and systemic inflammation can influence the blood-brain barrier, how circulating “good cholesterol” can protect the blood vessels and may be dysfunctional in AD, and a whole lot about cerebral small vessel disease. ------------------------------------------------------------------ To receive the list ...
80 - Understanding ApoE in Alzheimer's Disease: September 2020
December 18, 2020 04:13 - 33 minutes - 31.1 MBIn this episode, Courtney will update you on papers published in September 2020 on the Disease Mechanisms of ApoE. You will hear about cognitive impacts of ApoE, ethnic variability in ApoE, Neuroimaging of ApoE isoforms, and even some additional genetic implications of ApoE. List of Sections: Impact on Cognitive Abilities: 3.00 Ethnic Variability Behind ApoE Isoforms: 14.17 Neuroimaging with ApoE Isoforms: 18.20 Genetic Mechanisms of ApoE: 24.07 ------------------------------------------...
79- Treatments Targeting Oxidative Stress, Metabolism, & Behaviour in Alzheimer's Disease: September 2020
December 18, 2020 01:37 - 35 minutes - 32.9 MBIf you can’t quite decide which episode to listen to, maybe give this one a try. We’re covering preclinical models of AD as it pertains to mitochondria, autophagy, metabolism, behaviour, and much much more. Join Anusha so she doesn’t have to explore all these exciting papers all by herself! List of Sections: Mitochondria: 1.31 Autophagy/Metabolism: 5.34 Behaviour: 12.12 Other: 23.07 ------------------------------------------------------------------ To receive the list of papers ...
79- Treatments Targeting Oxidative Stress, Metabolism, & Behaviour in Azheimer's Disease: September 2020
December 18, 2020 01:37 - 35 minutes - 32.9 MBIf you can’t quite decide which episode to listen to, maybe give this one a try. We’re covering preclinical models of AD as it pertains to mitochondria, autophagy, metabolism, behaviour, and much much more. Join Anusha so she doesn’t have to explore all these exciting papers all by herself! List of Sections: Mitochondria: 1.31 Autophagy/Metabolism: 5.34 Behaviour: 12.12 Other: 23.07 ------------------------------------------------------------------ To receive the list of papers ...
78 - Multi-Targeted Treatment Approaches for Alzheimer's Disease Part 2 + Gene Therapy: September 2020
December 13, 2020 23:00 - 20 minutes - 19.2 MBThis episode is the second half of a two part series covering papers published in September 2020 on treatment approaches with multiple targets for Alzheimer’s disease. For part 1 of this series, check out episode 74! In this part, we’ll take a look at papers targeting many different AD processes, including oxidative stress, cholinesterase activity, and amyloid beta formation. The final paper in this episode will cover a new study using gene therapy to target AD. -----------------...
77 - Oxidative Stress, Autophagy and the Gut Microbiome in Alzheimer's Disease: September 2020
December 11, 2020 04:00 - 32 minutes - 29.7 MBYou'll hear about how mechanisms of oxidative stress, autophagy and the gut microbiome may contribute to AD pathology, as Abdullah updates you on the new papers from September 2020 on these topics. Enjoy! Sections in this episode: Oxidative stress (6) 2:15 Autophagy (2) 13:52 Gut microbiome (1) 19:53 ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 -------...
76 - The Genetic Landscape of Sex Differences and More in Alzheimer's Disease: September 2020
December 10, 2020 20:23 - 24 minutes - 22.1 MBIn this episode, Judy goes over papers published in September 2020 that focus on sex differences in Alzheimer’s disease. We also cover a few papers that did not quite fit into our other genetics-themed episodes, including AD-related stigma, lewy body dementia and overlapping risk factors of AD and Parkinson’s disease. Tune in to learn more! Sections in this episode: APOE 1:10 Female-specific AD risks 4:45 CERAD 11:32 Diabetes 15:25 Other 16:38 To learn more about the Bob and Diane...
75 - Risk Factors in Alzheimer's Disease Part 3: September 2020
December 08, 2020 20:00 - 29 minutes - 27.4 MBNaila is back to round off the non-genetic risk factors for September, with 6 papers on a variety of potential comorbidities, and 7 more on epidemiological studies and the interaction of various modifiable risk factors. We cover a lot of ground and geographic locations this episode, so buckle in for a solid - but hopefully riveting - half hour of information! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: ...
74 - Multi-Targeted Treatment Approaches for Alzheimer's Disease Part 1: September 2020
December 06, 2020 20:00 - 24 minutes - 22.6 MBIn this episode, Alex will be covering papers published in September 2020 within the category of novel drug development, that focus on multi-targeted approaches to Alzheimer’s disease treatment. We’ll take a look at papers targeting many different AD processes, including oxidative stress, cholinesterase activity, and amyloid beta formation. Part 2 will be coming out shortly! ------------------------------------------------------------------ To receive the list of papers covered, please f...
73 - Risk Factors for Alzheimer's Disease Part 2: September 2020
December 04, 2020 03:00 - 32 minutes - 29.5 MBIn this episode, Naila goes through 13 papers that explore how benzodiazepine and anticholinergic drug use affect individuals with dementia, whether exposure to certain air pollutants increase the risk of AD, and how cognitive reserve - whether in the form of occupation, bilingualism or education - may protect against cognitive decline. Enjoy! ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> ht...
72 - Synaptic Transmission in Alzheimer's Disease: September 2020
December 03, 2020 22:00 - 20 minutes - 18.5 MBWhat is it about neurotransmission that is so difficult to regulate in Alzheimer's? Anusha will tell you in this episode, so tune in if you're interested in the role of cholinergic and glutamatergic transmission, or the role of the hippocampus in AD. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiNDR_podcast ------...
71 - Amyloid-beta mediated toxicity: Alzheimer's Disease September 2020
December 02, 2020 01:09 - 26 minutes - 24.1 MBThis episode, hosted by Jacques, explores many facets of amyloid-beta mediated toxicity. First, we run through the structure-toxicity relationships of mutant amyloid-beta. Second, we investigate the interaction of amyloid-beta oligomers with membranes and their effect on vesicular trafficking and endocytosis. And lastly, we finish the episode on insights into the effects of amyloid-beta on neurotransmitter systems in AD. ------------------------------------------------------------------ ...
70 - Risk Factors in Alzheimer's Disease Part 1 : September 2020
November 30, 2020 05:37 - 29 minutes - 26.9 MBIn the first of 3 episodes on AD risk factors for September 2020, Naila covers some of the most studied (arguably) modifiable risk factors, including diet, exercise and sleep. You'll also hear about the effects of hormones and common comorbidities such as diabetes and cardiovascular disease. As many of these factors relate to one another, this will give you a good overview of the literature on common AD risk factors in September 2020! Major Sections: Diet (1.00) Body Mass, Dia...
70 - Risk Factors in Alzheimer's Disease Part 1: September 2020
November 30, 2020 05:37 - 29 minutes - 26.9 MBIn the first of 3 episodes on AD risk factors for September 2020, Naila covers some of the most studied (arguably) modifiable risk factors, including diet, exercise and sleep. You'll also hear about the effects of hormones and common comorbidities such as diabetes and cardiovascular disease. As many of these factors relate to one another, this will give you a good overview of the literature on common AD risk factors in September 2020! Major Sections: Diet (1.00) Body Mass, Diabetes, Ca...
69 - Treatments Targeting Synaptic Transmission in Alzheimer's Disease: September 2020
November 29, 2020 23:46 - 24 minutes - 22.6 MBAre you invested in the role of neurotransmission in Alzheimer’s disease? Well then buckle in because in this episode, Anusha will go over the latest and greatest compounds that target disease state changes to synaptic transmission in animal and in vitro models of Alzheimer’s. This episode covers the papers published in September of 2020 that use animal models and tissue culture to test the effects of novel compounds for their effects in rescuing synaptic transmission changes in AD. We’ll h...
SPECIAL: On Scicomm & Podcasting, with BrainBuzz!
November 28, 2020 08:50 - 37 minutes - 34 MBSarah and Elyn are joined by Kyle and Drake from BrainBuzz Podcast to share our journey, growth, and challenges with starting a podcast for science communication in Psychology for them, and Neuroscience for us. What is it like to talk about our research at cocktail parties? What does starting a podcast require? How does one manage to say "neurodegenerative" without stuttering? This is the second of two crossover episodes. Listen to the first part on Apple Podcast on BrainBuzz: https:/...
67 - More on Disease Mechanisms in Alzheimer's Disease: August 2020
November 27, 2020 07:00 - 23 minutes - 21.9 MBIn this episode, Elyn takes you through a very diverse set of papers on Alzheimer’s disease mechanisms - catching all of the papers that didn’t slot nicely into other episodes. The topics span a wide range from how the reflex of your pupils adjusting to light may be an early indicator of AD, to potentially pathogenic crystals in post-mortem AD brain tissue. There are also several RNA-based papers and signalling pathway papers in the mix, so tune in to learn something new! ------------------...
66- Tau and Other Protein-Related Pathology: Alzheimer's Disease 2020
November 27, 2020 03:25 - 36 minutes - 33.6 MBToday’s episode is on protein expression, aggregation, misfolding and pathology, with an emphasis on tau pathology in Alzheimer’s Disease and we are rounding off the papers published in August 2020. If you are interested in tau spreading in neurodegenerative disease, protein dysfunction in disease and new potential therapeutic targets, Alyssa has got you covered. ------------------------------------------------------------------ To receive the list of papers covered, please fill this for...
66- Tau and Other Protein-Related Pathology: Alzheimer's Disease August 2020
November 27, 2020 03:25 - 36 minutes - 33.6 MBToday’s episode is on protein expression, aggregation, misfolding and pathology, with an emphasis on tau pathology in Alzheimer’s Disease and we are rounding off the papers published in August 2020. If you are interested in tau spreading in neurodegenerative disease, protein dysfunction in disease and new potential therapeutic targets, Alyssa has got you covered. ------------------------------------------------------------------ To receive the list of papers covered, please fill this for...
65 - GWAS, Transcriptomics, & New Tools for Genetic Research: Alzheimer’s Disease August 2020
November 25, 2020 02:25 - 33 minutes - 30.6 MBNaila is back to round off our risk factors section with an episode on genome-wide association studies, transcriptomic research, combining genetics and neuroimaging data, and new tools to make all this work easier. Tune in to learn more about the techniques used to study the genetic underpinnings of AD, and perhaps to learn some long gene names to impress people at the next party you attend - especially if you can still remember them by then. -----------------------------------------------...
64 - Cerebrovascular Changes : Alzheimer's Disease August 2020
November 23, 2020 07:00 - 25 minutes - 23.6 MBWith over 700km of blood vessels in the brain, it’s no surprise that brain and vascular health are closely related. In this episode, Elyn takes you through papers published in August 2020 on cerebrovascular changes in AD. Tune in to learn more about amyloid clearance, platelet aggregation, and changes in the neurovascular unit over the course of the disease. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: ...
63 - More on Diagnostic Tools: Alzheimer's Disease August 2020
November 23, 2020 02:00 - 16 minutes - 15.3 MBToday’s episode is all about Diagnostic Tools and Imaging papers published in August 2020. As you will soon see, these papers explore a wide range of topics including potential biomarkers of AD, hormone markers and EEG analyses. While these papers didn’t quite fit into some of the other diagnostic tools and Imaging subthemes discussed in previous and upcoming episodes (such cognitive testing, imaging tools, fluid biomarkers, and using Amyloid and tau level for diagnosis and classification), ...
62 - Novel Drug Development-Part 3: Alzheimer's Disease June 2020
November 22, 2020 18:00 - 25 minutes - 23.1 MBn this episode, Alex will be covering papers published in August 2020 within the category of novel drug development, that focus on multi-targeted approaches to Alzheimer’s disease treatment, and a few papers that don’t quite fit under any of the themes we’ve covered so far. We’ll take a look at studies targeting many different AD processes, including oxidative stress, cholinesterase activity, and amyloid beta formation. ------------------------------------------------------------------ To...
61 - More on Biomarkers: Alzheimer's Disease August 2020
November 20, 2020 07:00 - 32 minutes - 30.1 MBNaila covers a wide variety of biomarkers and topics from papers published in August 2020 on Alzheimer's disease: identifying biomarkers of cognition and memory in cognitively unimpaired older adults, biomarkers that can help predict AD progression and differentiation, new biomarker assays and tools for improved diagnosis, EEG, metabolic profiling... ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: -------...
60 - Novel Drug Development Part 2 : Alzheimer's Disease August 2020
November 20, 2020 04:34 - 35 minutes - 32.3 MBIn this episode, Marcia talks about papers published in August 2020 within the novel drug development category that focus on targeting tau, the cholinergic system, mitochondria, metabolism and the immune system, as a way to combat Alzheimer's Disease. Check out episode 56 for the first part, where you'll hear more on novel drug development targeting Amyloid-beta production, aggregation, and toxicity. ------------------------------------------------------------------ To receive the list of...
59 - Detecting Amyloid & Tau in the Brain Part 2: Alzheimer's Disease August 2020
November 19, 2020 18:49 - 18 minutes - 16.6 MBJudy covers the second half of papers released in August 2020 on amyloid or tau protein detection in the brain. This selection features mouse models, machine learning, mass spectrometry and other cool methods to detect these biomarkers of Alzheimer’s disease. Check episode 39 for the first part. We hope you find this episode useful and accessible. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> ...
58 - Blood Biomarkers: Alzheimer's Disease August 2020
November 18, 2020 07:55 - 33 minutes - 30.3 MBToday we have another episode focused on the latest findings in Alzheimer’s disease blood biomarkers research, where Elyn covers abstracts from papers published in August 2020. These papers were clumped together based on the fact that they all focused on measuring something in the blood to either predict or diagnose Alzheimer disease – making them blood biomarkers! In this episode, you’ll hear about a range of analytes that were useful in diagnosing, or predicting Alzheimer disease. Some of...
57 - Metabolism, Mitochondrial (Dys)function, Oxidative Stress, Autophagy, & Gut Microbiome: Alzheimer's Disease August 2020
November 18, 2020 06:58 - 34 minutes - 31.8 MBFeeling PERK-y? An eclectic assortment of papers that address Alzheimer’s disease mechanisms in various ways awaits you in this episode. Anusha Kamesh will be guiding your journey through papers released in August of 2020 that concern metabolism, mitochondrial function, oxidative stress, autophagy, and gut microbiome ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pam...
56 - Novel Drug Development Part 1: Alzheimer's Disease August 2020
November 18, 2020 03:35 - 34 minutes - 32 MBMarcia will tell you about papers published in August 2020 within the Novel drug development category that focus on all things Amyloid-beta. She will cover research focussed on targeting Amyloid-beta production, aggregation, and toxicity, as a way to combat AD. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiNDR_podcast ...
55 - Refining & Repurposing Treatments: Alzheimer's Disease August 2020
November 16, 2020 10:31 - 30 minutes - 27.6 MBWe may not have a disease-modifying agent for Alzheimer’s disease yet, but there are several approved medications that can help slow down the progression of the disease. Can we improve these medications and make them more potent? Are there different ways we can administer them to improve their efficacy? And while we are talking about approved medications, are there any hidden gems on the market that are being used to treat let’s say diabetes, or hypertension..that can also help in treating A...
54 - CSF Biomarkers: Alzheimer's Disease August 2020
November 16, 2020 03:00 - 20 minutes - 18.5 MBIn this episode, Alex covers the latest research involving CSF biomarkers as a critical diagnostic tool in Alzheimer’s Disease identification and treatment. You’ll hear about some of the more typical clinical CSF biomarkers seen in AD, as well as the signature CSF AD biomarker profile, and you’ll also learn about how some of these CSF biomarkers relate to the different stages of AD progression and severity. ------------------------------------------------------------------ To receive t...
53 - Understanding ApoE: Alzheimer's Disease August 2020
November 16, 2020 01:00 - 25 minutes - 23.6 MBIn this episode, Courtney will update you on papers published in August 2020 on the genetic landscapes of ApoE. You will hear about models of ApoE, ethnic variability in ApoE, clinical implications of ApoE, and even some molecular mechanisms of ApoE. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAFM8pamdgk6 ------- or by tweeting at us: @AMiNDR_podcast ----------...
SPECIAL: ONE YEAR WITH AMINDR!
November 15, 2020 05:08 - 1 hour - 61.6 MBWhat role does social media play in academia and science communication nowadays? How can we keep our biases from interfering with fair reporting and objective coverage? Do we need to revise our inclusion criteria for the papers we cover? How relevant is the categorization of research by disease when there is so much overlap in underlying mechanisms? And how much responsibility do we hold through our podcast in shaping people’s understanding of these papers? Today you will hear from Sarah Lo...
51 - Cognitive Testing for Diagnosis: Alzheimer's Disease August 2020
November 13, 2020 05:00 - 35 minutes - 32.6 MBEllen tells you about the latest papers on cognitive testing for AD and mild cognitive impairment! This includes papers that delve deeper into how cognition is affected in AD and other disorders, and in some cases compare these changes to neurological data. Other papers validate existing cognitive assessment tools, or describe brand new ones, including new analysis algorithms and computer-based testing. Enjoy the episode! ------------------------------------------------------------------ ...
50 - Amyloid-beta Aggregation: Alzheimer's Disease August 2020
November 13, 2020 04:00 - 24 minutes - 22.3 MBListen to Jacques as he recites tongue-twisters and updates you on the latest papers on amyloid-beta aggregation and toxicity in AD from August, 2020! We hope you like the episode, and if you're interested in amyloid pathology in AD, you might want to check out Jacques' last episode as well, episode 47 on APP processing. ------------------------------------------------------------------ To receive the list of papers covered, please fill this form: --------> https://forms.gle/CVVbznAF...