OUD Treatment and Intent To Treat Analysis
Yeah, No Journal Club
English - November 04, 2020 13:11 - 20 minutes - 18.4 MB - ★★★★★ - 4 ratingsMental Health Health & Fitness substance abuse therapy psychiatry mental health treatment substance abuse treatment Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
We discuss the X:BOT primary outcomes paper in this episode of the podcast. Use the link above or the citation below to find it. Take a look at the figures!
JD Lee et al. Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X:BOT): a multicenter, open-label, randomized controlled trial. Lancet 2018. 391:309-318.
X:BOT rationale and design paper
In this fascinating and thoughtful paper, the X:BOT authors discuss the study design choices they considered and how they selected various aspects of the trial design. A great read for those with interest in OUD treatment or clinical trials design.
X:BOT cost effectiveness analysis
This planned analysis of the X:BOT data provides an additional lens for determining which medication is the best option.
Thorough but brief review on the use of buprenorphine.