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Tizanidine is primarily broken down by CYP1A2. Ciprofloxacin can inhibit CYP1A2 and cause higher tizanidine concentrations.

Tizanidine has a similar classification as clonidine. Pay attention to adverse effects like hypotension and bradycardia.

When patients taking routine tizanidine stop taking it, there is potential for a discontinuation syndrome that may lead to rebound hypertension.

Dry mouth and CNS depression are common adverse effects of tizanidine.

Tizanidine is primarily broken down by CYP1A2. Ciprofloxacin can inhibit CYP1A2 and cause higher tizanidine concentrations.


Tizanidine has a similar classification as clonidine. Pay attention to adverse effects like hypotension and bradycardia.


When patients taking routine tizanidine stop taking it, there is potential for a discontinuation syndrome that may lead to rebound hypertension.


Dry mouth and CNS depression are common adverse effects of tizanidine.


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