On this episode of the podcast, I cover guanfacine pharmacology, adverse effects, drug interactions, and much more.

Guanfacine is a central acting alpha-2 agonist that has the brand names of Tenex and Intuniv.

Because of guanfacine's mechanism of action, it suppresses the sympathetic response leading to a drop in pulse and blood pressure.

It is important to remind patients that the onset of action is slow in the management of ADHD with guanfacine. I discuss this further in this podcast episode.

On this episode of the podcast, I cover guanfacine pharmacology, adverse effects, drug interactions, and much more.


Guanfacine is a central acting alpha-2 agonist that has the brand names of Tenex and Intuniv.


Because of guanfacine’s mechanism of action, it suppresses the sympathetic response leading to a drop in pulse and blood pressure.


It is important to remind patients that the onset of action is slow in the management of ADHD with guanfacine. I discuss this further in this podcast episode.


Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!


Support The Podcast and Check Out These Amazing Resources!

Flippin’ Pharmacology Flash Cards


Pharmacology Crossword Puzzle Book (Over 2,000 Clues/Questions!)


NAPLEX Study Materials


BCPS Study Materials


BCACP Study Materials


BCGP Study Materials


BCMTMS Study Materials


Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)


Guide to Drug Food Interactions (Amazon Best Seller)


Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)


Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)