Heart Disease Masterclass - Tom Dayspring, M.D. – Part 2: Lipid Transport & HDL Cholesterol
Foolproof Mastery
English - January 07, 2023 14:33 - 39 minutes - 35.8 MBSelf-Improvement Education Homepage Download Google Podcasts Overcast Castro Pocket Casts RSS feed
In this series, Thomas Dayspring, M.D., one of the world's most recognised experts in lipidology, shares his breadth of knowledge on heart disease prevention. Part 2 covers lipid transport, cholesterol removal from cells & HDL cholesterol.
VLDL, LDL & chylomicron residence time [02:03]
Apolipoprotein B (ApoB) & atherosclerosis [04:24]
Where are VLDL and chylomicron particles made ? [05:13]
Structure and function of triglycerides [05:40]
Triglyceride hydrolysis, genetics & lipoprotein lipase [06:40]
Phospholipids, phospholipid transfer protein & HDL synthesis from ApoA-I [09:50]
Function of ApoB & ApoA-I in the body [10:48]
What happens to VLDL & chylomicron remnants ? [14:14]
The LDL receptor-related protein (LRP) [15:50]
Apolipoprotein E (ApoE) [16:10]
Hepatic lipase, removal of ApoE in VLDL and a route to LDL [17:30]
HDL as cholesterol acceptors [17:53]
How does a HDL particle get rid of its cholesterol ? [20:58]
Difference between the LDL receptor & LDL receptor related protein [25:43]
Total, indirect & direct reverse cholesterol transport [26:10]
Why did evolution make LDL circulate for 3-5 days ? [27:00]
The big picture on lipid transportation [27:28]
How the Framingham Study created the misconception that raising HDL “good” cholesterol is all that matters ? [30:50]
Results from other clinical trials & HDL-C fallacies [32:30]
Interactive Quiz: https://www.surveymonkey.com/r/N8XK5LL
Give Tom a follow on Twitter: https://twitter.com/Drlipid
Other appearances from Tom:
Drive Podcast
https://www.youtube.com/watch?v=PllTHYgWpuw
Wellness: Fact vs. Fiction
https://podcasts.apple.com/us/podcast/a-masterclass-in-cholesterol-and-lipid-lowering/id1447250475?i=1000581954971
Nutrition Made Simple
lp(a):
https://www.youtube.com/watch?v=-WRRyG8il4g
Dietary cholesterol:
https://www.youtube.com/watch?v=GkWMDnTyxfo
Coronary Calcium Score (CAC):
https://www.youtube.com/watch?v=gxIeRUbHauw
Narrative glossary on lipids provided by Tom:
https://peterattiamd.com/glossary-lipids/
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