The Food and Drug Administration has played a large role in the COVID-19 response and is also amid widespread digital transformation. Chief Technology Officer Vid Desai joined the agency two years ago and brings private-sector experience from the health technology industry. Desai observes the similarities of FDA’s tech focus with those in his private industry experiences, discusses how he's driving change from a business perspective to meet the mission, and shares examples of how innovation in data can unlock efficiencies and opportunities for medical devices and the public.