ER-Rx: An ER + ICU Podcast
155 episodes - English - Latest episode: about 1 year ago -ER-Rx is a podcast dedicated to informing emergency room/ intensive care unit physicians, residents, pharmacists, advanced practice providers, and nurses on appropriate and optimal use of medications. This podcast will provide laid-back, fun, useful information in easily digestible portions. Tune in each week as we review recently-published guidelines and studies, answer medication-related questions, present "Grand Rounds" on a wide variety of clinical topics, and enjoy "An Expert Talks" where we invite guests outside of the pharmacy department to discuss a critical topic. Our host, Dr. Adis Keric, is a Board Certified Pharmacotherapy Specialist and a Board Certified Critical Care pharmacist who currently works in the emergency room and intensive care units at a large, level I trauma center. Adis has more than 8 years of hospital pharmacy experience, including 2 years of residency. He acts as a PGY-1 and PGY-2 critical care pharmacy residency preceptor in the emergency room, surgical intensive care unit, medical intensive care unit, and the neurocritical care unit. He is also a preceptor for local pharmacy students and is heavily involved in the research aspect of the pharmacy residency programs at his site.
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Episodes
Episode 34- Adult ACLS: Updated recommendations and clinical pearls
December 03, 2020 10:00 - 9 minutes - 6.6 MBIn part 1 of the cardiac arrest series, we review some key recommendations and clinical pearls from the 2020 adult BLS and ACLS guidelines. References: Panchal AR, Bartos JA, Cabanas JG, et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2020; 142: S366-S468 Edelson DP, Sasson C, Chan PS, et al. Interim Guidance for Basic and Advanced Life Support in Adults, Ch...
Episode 33- Shock through the heart: Is two better than one?
November 26, 2020 10:00 - 6 minutes - 4.44 MBWhat is dual/double defibrillation? How does it work? Does it improve patient outcomes? Find out this week! References: Miraglia D, Miguel LA, Alonso W. Double defibrillation for refractory in- and out-of-hospital cardiac arrest: a systematic review and meta-analysis. J Emerg Med. 2020; 59 (4): 531-541 Panchal AR, Bartos JA, Cabanas JG, et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiova...
Episode 33- Shock through the heart: Is two better than one?
November 26, 2020 10:00 - 6 minutes - 4.44 MBWhat is dual/double defibrillation? How does it work? Does it improve patient outcomes? Find out this week! References: Miraglia D, Miguel LA, Alonso W. Double defibrillation for refractory in- and out-of-hospital cardiac arrest: a systematic review and meta-analysis. J Emerg Med. 2020; 59 (4): 531-541 Panchal AR, Bartos JA, Cabanas JG, et al. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiova...
Episode 32- Drug shortage debacle: Methohexital or ketamine for RSI
November 19, 2020 10:00 - 7 minutes - 5.41 MBWhat happens when/ if etomidate goes on shortage? Are methohexital or ketamine viable options for RSI in the ER? Find out this week. References: Farrell NM, Killius K, Kue R, et al. A comparison of etomidate, ketamine, and methohexital in emergency department rapid sequence intubation. J Emerg Med. 2020; 59(4): 508-514 Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes o...
Episode 31- Antiplatelet agents in ACS: Who rules the roost?
November 12, 2020 10:00 - 7 minutes - 4.86 MBIn this episode, we discuss the pros and cons of the main antiplatelet agents used in the setting of ACS. Who comes out on top? References: Norgard NB, DiNicolantonio JJ. Clopidogrel, prasugrel, or ticagrelor? A practical guide to use of antiplatelet agents in patients with acute coronary syndromes. Postgrad Med. 2013; 125(4): 91-102 Thachil J. Antiplatelet therapy- a summary for the general physicians. Clin Med. 2016; 16(2): 152-160 Disclaimer: The information contained within the ER-...
Episode 30- How fast can we give IV magnesium?
November 05, 2020 10:00 - 7 minutes - 4.9 MBThe rate of IV magnesium administration depends on the particular indication, dose, and patient-specific factors. Tune in for more details. References: Kaye P, O’Sullivan I. The role of magnesium in the emergency department. Emerg Med J. 2002; 19: 288-291 Grissinger M. Avoiding patient harm from a magnesium bolus dose. P & T. 2014; 39(2): 81-82 Preventing magnesium toxicity in obstetrics. ISMP. Updated October 5, 2005. Accessed November 2 2020. https://www.ismp.org/resources/preventing-m...
Episode 29- "We're all a little 'stitious:" Bad words, full moons, and black clouds
October 29, 2020 10:00 - 7 minutes - 5.37 MBDays away from Halloween, we discuss a few common ER superstitions. Are they actually legit? Or do you belive the data? Your call. References: Brookfield CR, Phillips PPJ, Shorten RJ. Q fever- the superstition of avoiding the word “quiet” as a coping mechanism: randomized controlled non-inferiority trial. BMJ. 2019; 367: 16446 Lamb JN, Howard AJ, Marciniak J. Does the word ‘quiet’ really make things busier? RCS Bull. 2017; 99: 133-136 Exadaktylos AK, Sclabas G, Siegenthaler A, et al. Fr...
Episode 29- "We're all a little 'stitious:" Bad words, full moons, and black clouds
October 29, 2020 10:00 - 7 minutes - 5.37 MBDays away from Halloween, we discuss a few common ER superstitions. Are they actually legit? Or do you belive the data? Your call. References: Brookfield CR, Phillips PPJ, Shorten RJ. Q fever- the superstition of avoiding the word “quiet” as a coping mechanism: randomized controlled non-inferiority trial. BMJ. 2019; 367: 16446 Lamb JN, Howard AJ, Marciniak J. Does the word ‘quiet’ really make things busier? RCS Bull. 2017; 99: 133-136 Exadaktylos AK, Sclabas G, Siegenthaler A, et al. Fr...
Episode 28- Blink and you miss it: an easily missed cause of bradycardia and hypotension
October 22, 2020 10:00 - 5 minutes - 3.64 MBBradycardic? Hypotensive? Keep the agent discussed in this week's episode in mind when reviewing your patient's medication list. References: Rains J, Kesterson J. Ocular timolol as the causative agent for symptomatic bradycardia in an 89-year-old female. Am J Emerg Med. 2020; Article in Press Abbas SA, Hamadani SM, Ahmad U, et al. Ophthalmic timolol and hospitalization for symptomatic bradycardia and syncope: a case series. Cureus. 2020; 12(3): e7270 Wang Z, Denys I, Chen F, et al. Compl...
Episode 27- "More Squeeze, Please:" Part 2: Clots and COVID
October 15, 2020 10:00 - 9 minutes - 6.7 MBIn Part 2 of this "Mini Grand Rounds" series, we discuss important side effects of ATII including thrombosis, especially in the setting of COVID. References: Celi A, Cianchetti S, Dell’Omo G, Pedrinelli R. Angiotensin II, tissue factor and the thrombotic paradox of hypertension. Expert Review Cardiovasc Therapy. 2010. 8 (12) Senchenkova EY, Russell J, Almeida-Paula LD, et al. Angiotensin II-mediated microvascular thrombosis. Hypertension. 2010; 56 (6): 1089-1095 Zhang P, Zhu L, Cai J, e...
Episode 26- "More Squeeze, Please:" Part I: ATHOS-3 and me
October 08, 2020 10:00 - 8 minutes - 6.11 MBIn Part 1 of this "Mini Grand Rounds" series, we discuss Angiotensin II use for vasodilatory shock, reviewing the ATHOS-3 trial and real-world experiences. References: Khanna A, English SW, Wang XS, et al. Angiotensin II for the treatment of vasodilatory shock. NEJM. 2017; 377: 419-430 Farina N, Bixby A, Alaniz C. Angiotensin II brings more questions than answers. P T. 2019; 43 (11): 685- 687 Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and...
Episode 26- "More Squeeze, Please:" Part I: ATHOS-3 and me
October 08, 2020 10:00 - 8 minutes - 6.11 MBIn Part 1 of this "Mini Grand Rounds" series, we discuss Angiotensin II use for vasodilatory shock, reviewing the ATHOS-3 trial and real-world experiences. References: Khanna A, English SW, Wang XS, et al. Angiotensin II for the treatment of vasodilatory shock. NEJM. 2017; 377: 419-430 Farina N, Bixby A, Alaniz C. Angiotensin II brings more questions than answers. P T. 2019; 43 (11): 685- 687 Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and...
Episode 25: Procainamide for atrial fibrillation/ flutter conversion
October 01, 2020 10:00 - 7 minutes - 5.17 MBShould we be giving procainamide to patients with atrial fibrillation/ flutter? We discuss two clinical trials that may give us some answers. References: Stiell IG, Clement CM, Symington C, et al. Emergency department use of intravenous procainamide for patients with acute atrial fibrillation or flutter. Acad Emerg Med. 2007; 14: 1158-1164 Stiell IG, Sivilotti MLA, Taljaard M, et al. Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibri...
Episode 25- Procainamide for atrial fibrillation/ flutter conversion
October 01, 2020 10:00 - 7 minutes - 5.17 MBShould we be giving procainamide to patients with atrial fibrillation/ flutter? We discuss two clinical trials that may give us some answers. References: Stiell IG, Clement CM, Symington C, et al. Emergency department use of intravenous procainamide for patients with acute atrial fibrillation or flutter. Acad Emerg Med. 2007; 14: 1158-1164 Stiell IG, Sivilotti MLA, Taljaard M, et al. Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibri...
Episode 24- An expert talks: Methemoglobinemia
September 24, 2020 10:00 - 17 minutes - 12.4 MBThis week we discuss methemoglobinemia with Dr. KC Lee, a clinical pharmacist who recently completed her clinical toxicology/ emergency medicine fellowship. * Note: Although rare, there has been a slight increase in hydroxychloroquine-associated methemoglobinemia in the setting of COVID References: Price DP, Howland MA. Methemoglobin inducers and methylene blue. Goldfrank’s Toxicologic Emergencies 9th edition: 1698-1710. McGraw-Hill; New York: 2011 Methemoglobin. Hennepin Regional Poison...
Episode 24- An expert talks: Methemoglobinemia
September 24, 2020 10:00 - 17 minutes - 12.4 MBThis week we discuss methemoglobinemia with Dr. KC Lee, a clinical pharmacist who recently completed her clinical toxicology/ emergency medicine fellowship. * Note: Although rare, there has been a slight increase in hydroxychloroquine-associated methemoglobinemia in the setting of COVID References: Price DP, Howland MA. Methemoglobin inducers and methylene blue. Goldfrank’s Toxicologic Emergencies 9th edition: 1698-1710. McGraw-Hill; New York: 2011 Methemoglobin. Hennepin Regional Poison...
Episode 23- The ammonia level: what is it good for?
September 17, 2020 10:00 - 5 minutes - 3.66 MBShould we be using ammonia levels to diagnose, determine the severity, or monitor the resolution of hepatic encephalopathy? References: Ninan J, Feldman L. Ammonia levels and hepatic encephalopathy in patients with known chronic liver disease. J Hosp Med. 2017 (8): 659-661 Gundling F, Zelihic E, Seidl H, et al. How to diagnose hepatic encephalopathy in the emergency department. Ann Hepatol. 2013; 12(1): 108-114 Ong JP, Aggarwal A, Krieger D, et al. Correlation between ammonia levels and...
Episode 23- The ammonia level: what is it good for?
September 17, 2020 10:00 - 5 minutes - 3.66 MBShould we be using ammonia levels to diagnose, determine the severity, or monitor the resolution of hepatic encephalopathy? References: Ninan J, Feldman L. Ammonia levels and hepatic encephalopathy in patients with known chronic liver disease. J Hosp Med. 2017 (8): 659-661 Gundling F, Zelihic E, Seidl H, et al. How to diagnose hepatic encephalopathy in the emergency department. Ann Hepatol. 2013; 12(1): 108-114 Ong JP, Aggarwal A, Krieger D, et al. Correlation between ammonia levels and...
Episode 22- One-time IV antibiotics prior to discharge
September 09, 2020 10:00 - 7 minutes - 4.93 MBIs giving your patient a one-time dose of IV antibiotics prior to discharge helpful? Or are you doing more harm than good? Tune in this week to find out! References: Mueller K, McCammon C, Skrupky L, Fuller BM. Vancomycin use in patients discharged from the emergency department: a retrospective observational cohort study. J Emerg Med. 2015; 49 (1): 50-57 Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for ...
Episode 22- One-time IV antibiotics prior to discharge
September 09, 2020 10:00 - 7 minutes - 4.93 MBIs giving your patient a one-time dose of IV antibiotics prior to discharge helpful? Or are you doing more harm than good? Tune in this week to find out! References: Mueller K, McCammon C, Skrupky L, Fuller BM. Vancomycin use in patients discharged from the emergency department: a retrospective observational cohort study. J Emerg Med. 2015; 49 (1): 50-57 Disclaimer: The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for ...
Episode 21- Esmolol in refractory VF arrest
September 01, 2020 10:00 - 6 minutes - 4.18 MBThis week we review a meta-analysis that looked at the use of esmolol in patients in refractory VF/pVT arrest. Will this change your practice? References: Miraglia D, Miguel LA, Alonso W. Esmolol in the management of pre-hospital refractory ventricular fibrillation: a systematic review and meta-analysis. Am J Emerg Med. 2020; 38: 1921-1934 Driver BE, Debaty G, Plummer DW, et al. Use of esmolol after failure of standard cardiopulmonary resuscitation to treat patients with refractory vent...
Episode 21- Esmolol in refractory VF arrest
September 01, 2020 10:00 - 6 minutes - 4.18 MBThis week we review a meta-analysis that looked at the use of esmolol in patients in refractory VF/pVT arrest. Will this change your practice? References: Miraglia D, Miguel LA, Alonso W. Esmolol in the management of pre-hospital refractory ventricular fibrillation: a systematic review and meta-analysis. Am J Emerg Med. 2020; 38: 1921-1934 Driver BE, Debaty G, Plummer DW, et al. Use of esmolol after failure of standard cardiopulmonary resuscitation to treat patients with refractory vent...
Episode 20- Cyanide: toxicology and antidotes
August 25, 2020 10:00 - 9 minutes - 6.84 MBIn this Mini Grand Rounds episode, we discuss cyanide toxicology and management, including antidotes. References: Holstege CP, Isom GE, Kirk MA. Cyanide and hydrogen sulfide. Goldfrank’s Toxicologic Emergencies 9th edition: 1678-1688. McGraw-Hill; New York: 2011 Cyanide. Hennepin Regional Poison Center Treatment Guidelines. Minnesota Poison Control System. Accessed 11/20/2017 Lawson-Smith P, Jansen EC, Hyldegaard O. Cyanide intoxication as part of smoke inhalation- a review on diagnosis...
Episode 19: Public service announcement: stop the steroid bomb!
August 18, 2020 10:00 - 4 minutes - 2.91 MBStop the steroid bomb! If you are giving 125 mg IV methylprednisolone (Solu-Medrol) to your asthma or COPD exacerbation patients, that may be too much. References: Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease 2020 report. https://goldcopd.org (Accessed on August 14, 2020) Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. www.gi...
Episode 19- Public service announcement: stop the steroid bomb!
August 18, 2020 10:00 - 4 minutes - 2.91 MBStop the steroid bomb! If you are giving 125 mg IV methylprednisolone (Solu-Medrol) to your asthma or COPD exacerbation patients, that may be too much. References: Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease 2020 report. https://goldcopd.org (Accessed on August 14, 2020) Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. www.gi...
Episode 19- Public service announcement: stop the steroid bomb!
August 18, 2020 10:00 - 4 minutes - 2.91 MBStop the steroid bomb! If you are giving 125 mg IV methylprednisolone (Solu-Medrol) to your asthma or COPD exacerbation patients, that may be too much. References: Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease 2020 report. https://goldcopd.org (Accessed on August 14, 2020) Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. www.gi...
Episode 18- Ventilator-associated tracheo-what?
August 11, 2020 10:00 - 5 minutes - 3.57 MBTune in as we discuss ventilator-associated tracheobronchitis and what the guidelines say we should do about this little-known entity! References: Nseir S, Favory R, Jozefowicz E, et al. Antimicrobial treatment for ventilator-associated tracheobronchitis: a randomized, controlled, multicenter study. Crit Care. 2008: 12; R62 Koulenti D, Arvaniti K, Judd, M, et al. Ventilator-associated tracheobronchitis: to treat or not to treat? Antibiotics. 2020: 9 (2): 51 Metlay JP, Waterer GW, Long A...
Episode 17- The Emergency Medical Minute meets ER-Rx
August 04, 2020 10:00 - 19 minutes - 13.2 MBIn case you missed it, last week Dr. Nick Tsipis from the Emergency Medical Minute discussed a few rapid-fire ER topics with our host, Adis Keric. Check out the full episode here or on the Emergency Medical Minute podcast! *Correction to figures quoted on anticoagulation reversal pricing. High-dose Andexxa regimen maxes out around $60,000 and Kcentra maxes out at $6,000. So there is still a massive price difference, but not as high as quoted in the audio. References: Metlay JP, Waterer ...
Episode 16- "HALT" the use of TXA in GI bleeds?
July 28, 2020 10:00 - 7 minutes - 5.07 MBThis week, we review the "HALT-IT" trial. Will you routinely give your patients TXA (tranexamic acid) in the setting of GI bleeds after reading this study? References: Roberts I, Shakur-Still H, Afolabi A, et al. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet. 2020; 395: 1927-36 Shakur H, Roberts I, Fawole B, ...
Episode 16- "HALT" the use of TXA in GI bleeds?
July 28, 2020 10:00 - 7 minutes - 5.07 MBThis week, we review the "HALT-IT" trial. Will you routinely give your patients TXA (tranexamic acid) in the setting of GI bleeds after reading this study? References: Roberts I, Shakur-Still H, Afolabi A, et al. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet. 2020; 395: 1927-36 Shakur H, Roberts I, Fawole B, ...
Episode 15- The misleading "sulfa" allergy
July 21, 2020 11:00 - 3 minutes - 2.6 MBToday, we discuss what it means to have a "sulfa" allergy. Are things such as furosemide and tamsulosin really contraindicated in these patients? Tune In! References: Smith WB. ‘Sulfur allergy’ label is misleading. Aust Prescr. 2008; 31: 8-10 Ponka D. Approach to managing patients with sulfa allergy. Can Fam Physician. 2006; 52(11): 1434-1438 Strom BL, Schinnar R, Apter AJ, et al. Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics. NEJM. 2003; 34...
Episode 15- The misleading "sulfa" allergy
July 21, 2020 11:00 - 3 minutes - 2.6 MBToday, we discuss what it means to have a "sulfa" allergy. Are things such as furosemide and tamsulosin really contraindicated in these patients? Tune In! References: Smith WB. ‘Sulfur allergy’ label is misleading. Aust Prescr. 2008; 31: 8-10 Ponka D. Approach to managing patients with sulfa allergy. Can Fam Physician. 2006; 52(11): 1434-1438 Strom BL, Schinnar R, Apter AJ, et al. Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics. NEJM. 2003; 34...
Episode 14- SARS-CoV-2 antibody test
July 14, 2020 10:00 - 6 minutes - 4.78 MBWhat does a negative or positive antibody test mean? Should it change our behavior? Do we have to view the results in the setting of where we are located? Tune in this week! References: Interim guidelines for COVID-19 antibody testing. CDC. May 23, 2020. Accessed July 7, 2020. Abbott ARCHITECT SARS-CoV-2 IgG Instructions for Use. H14806R01. April 2020 Bryan A, Pepper G, Wener MH, et al. Performance characteristics of the Abbott Architect SARS-CoV-2 IgG assay and seroprevalence testing ...
Episode 14- SARS-CoV-2 antibody test
July 14, 2020 10:00 - 6 minutes - 4.78 MBWhat does a negative or positive antibody test mean? Should it change our behavior? Do we have to view the results in the setting of where we are located? Tune in this week! References: Interim guidelines for COVID-19 antibody testing. CDC. May 23, 2020. Accessed July 7, 2020. Abbott ARCHITECT SARS-CoV-2 IgG Instructions for Use. H14806R01. April 2020 Bryan A, Pepper G, Wener MH, et al. Performance characteristics of the Abbott Architect SARS-CoV-2 IgG assay and seroprevalence testing ...
Episode 13- "Clot Busters:" Part 2: Cardiac arrest
July 07, 2020 10:00 - 10 minutes - 7.02 MBIn Part 2 of 2 of our "Mini Grand Rounds" series, we discuss the use of thrombolytics in the setting of cardiac arrest and wrap it up with our final recommendations. References: Lederer W, Lichtenberger C, Pechlaner C, et al. Recombinant tissue plasminogen activator during cardiopulmonary resuscitation in 108 patients with out‐of‐hospital cardiac arrest. Resuscitation 2001; 50(1): 71-76 Abu-Laban RB, Christenson JM, Innes GD, et al. Tissue plasminogen activator in cardiac arrest with puls...
Episode 12- "Clot Busters:" Part 1: Submassive and massive pulmonary embolism
June 30, 2020 11:00 - 10 minutes - 7.11 MBIn Part 1 of 2 of our "Mini Grand Rounds" series, we discuss the use of thrombolytics in the setting of submassive and massive pulmonary embolism. Tune in as we review studies and guidelines that discuss these agents in these settings, as well as appropriate dosing and administration of alteplase. References: Konstantinides S, Geibel A, Heusel G, et al. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. NEJM. 2002; 347(15): 1143-1150 Shari...
Episode 12- "Clot Busters:" Part 1: Submassive and massive pulmonary embolism
June 30, 2020 11:00 - 10 minutes - 7.11 MBIn Part 1 of 2 of our "Mini Grand Rounds" series, we discuss the use of thrombolytics in the setting of submassive and massive pulmonary embolism. Tune in as we review studies and guidelines that discuss these agents in these settings, as well as appropriate dosing and administration of alteplase. References: Konstantinides S, Geibel A, Heusel G, et al. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. NEJM. 2002; 347(15): 1143-1150 Shari...
Episode 11- Anaphylaxis: A pharmacologic management update
June 23, 2020 10:00 - 9 minutes - 6.79 MBWhat is the most important agent for anaphylaxis? What other treatments are only considered as adjuncts? How should I give these agents? Find out this week as we review updated anaphylaxis treatment guidelines published in April 2020! References: Shaker MS, Wallace DV, Golden DBK, et al. Anaphylaxis- a 2020 practice parameter update, systematic review, and grading of recommendations, assessment, development, and evaluation (GRADE) analysis. J Allergy Clin Immunol 2020; 146 (4): 1082-1123 ...
Episode 10- Alteplase door-to-needle times and long-term outcomes
June 16, 2020 11:00 - 6 minutes - 4.64 MBJoin us for a quick review on a recently-published study describing the association between alteplase door-to-needle times and long-term patient outcomes in the setting of ischemic stroke. Please subscribe to our Podcast ("ER-Rx") and leave us a review! References: Man S, Xian Y, Holmes DN, et al. Association between thrombolytic door-to-needle time and 1-year mortality and readmission in patients with acute ischemic stroke. JAMA; 2020: 323(21): 2170-2184 Gilbert BW, Huffman J. Effect o...
Episode 9- Carbapenem-resistant but cephalosporin-sensitive pseudomonas
June 09, 2020 11:00 - 8 minutes - 5.7 MBThis week, we discuss a strange and rare pseudomonas phenotype. Find out why these strains are resistant to carbapenems but usually not other antibiotics and the significance of these strains. Search "ER-Rx" on Apple Podcasts, Google Podcast, and YouTube. Also, check out our Instagram page: errxpodcast ! References: Gajdacas M. Carbapenem-resistant but cephalosporin-susceptible pseudomonas aeruginosa in urinary tract infections: opportunity for colistin sparing. Antibiotics. 2020; 9(4): 1...
Episode 9- Carbapenem-resistant but cephalosporin-sensitive pseudomonas
June 09, 2020 11:00 - 8 minutes - 5.7 MBThis week, we discuss a strange and rare pseudomonas phenotype. Find out why these strains are resistant to carbapenems but usually not other antibiotics and the significance of these strains. Search "ER-Rx" on Apple Podcasts, Google Podcast, and YouTube. Also, check out our Instagram page: errxpodcast ! References: Gajdacas M. Carbapenem-resistant but cephalosporin-susceptible pseudomonas aeruginosa in urinary tract infections: opportunity for colistin sparing. Antibiotics. 2020; 9(4): 1...
Episode 8- Is glucagon effective for relieving esophageal foreign bodies/ food impactions?
June 02, 2020 11:00 - 5 minutes - 3.91 MBIn this week's episode, we discuss a recently-published meta-analysis and summarize a couple of guidelines that discuss the management of esophageal foreign bodies/ food boluses. Find us on Apple Podcasts (iTunes), Google Podcasts, Spotify, and YouTube! References: Long B, Gottlieg M. Is glucagon effective for relieving acute esophageal foreign bodies and food impactions? Ann Emerg Med. 2020; 75(2): 299- 301 Peksa GD, DeMott JM, Slocum GW, et al. Glucagon for relief of acute esophageal f...
Episode 8- Is glucagon effective for relieving esophageal foreign bodies/ food impactions?
June 02, 2020 11:00 - 5 minutes - 3.91 MBIn this week's episode, we discuss a recently-published meta-analysis and summarize a couple of guidelines that discuss the management of esophageal foreign bodies/ food boluses. Find us on Apple Podcasts (iTunes), Google Podcasts, Spotify, and YouTube! References: Long B, Gottlieg M. Is glucagon effective for relieving acute esophageal foreign bodies and food impactions? Ann Emerg Med. 2020; 75(2): 299- 301 Peksa GD, DeMott JM, Slocum GW, et al. Glucagon for relief of acute esophageal f...
Episode 7- Epistaxis: A guideline review focusing on topical agents and prophylactic antibiotics
May 26, 2020 11:00 - 6 minutes - 4.8 MBDo we have any data on topical agent use to control nosebleeds? How about prophylactic antibiotics for patients with nasal packing in place? Find out on this week's episode. Follow us on YouTube, Instagram, and Google Podcasts! References: Tunkel DE, Anne S, Payne SC, et al. Clinical practice guideline: nosebleed (epistaxis). Am J Otolaryngol. 2020; 162(IS): S1-S38. Whitworth K, Johnson J, Wisniewski S, et al. Comparative effectiveness of topically administered tranexamic acid versus top...
Episode 7- Epistaxis: A guideline review focusing on topical agents and prophylactic antibiotics
May 26, 2020 11:00 - 6 minutes - 4.8 MBDo we have any data on topical agent use to control nosebleeds? How about prophylactic antibiotics for patients with nasal packing in place? Find out on this week's episode. Follow us on YouTube, Instagram, and Google Podcasts! References: Tunkel DE, Anne S, Payne SC, et al. Clinical practice guideline: nosebleed (epistaxis). Am J Otolaryngol. 2020; 162(IS): S1-S38. Whitworth K, Johnson J, Wisniewski S, et al. Comparative effectiveness of topically administered tranexamic acid versus top...
Episode 6- Can we use corticosteroids to reduce reintubation rates?
May 20, 2020 02:00 - 6 minutes - 4.83 MBIn this episode, we discuss the use of prophylactic corticosteroids for patients at high risk of reintubation. Please leave us a comment for your chance to win a medically-related prize! References: Kuriyama A, et al. Prophylactic corticosteroids for prevention of postextubation stridor and reintubation in adults: a systematic review and meta analysis. CHEST. 2017; 151(5): 1002-1010 Girard TD, et al. An official American Thoracic Society/ American College of Chest Physicians clinical pra...
Episode 6- Can we use corticosteroids to reduce reintubation rates?
May 20, 2020 02:00 - 6 minutes - 4.83 MBIn this episode, we discuss the use of prophylactic corticosteroids for patients at high risk of reintubation. Please leave us a comment for your chance to win a medically-related prize! References: Kuriyama A, et al. Prophylactic corticosteroids for prevention of postextubation stridor and reintubation in adults: a systematic review and meta analysis. CHEST. 2017; 151(5): 1002-1010 Girard TD, et al. An official American Thoracic Society/ American College of Chest Physicians clinical pra...
Episode 5- Subcutaneous neostigmine for Ogilvie's Syndrome
May 15, 2020 15:00 - 10 minutes - 7.01 MBIn this episode, we look into the pharmacological treatment of Ogilvie's Syndrome using subcutaneous neostigmine. Please remember to subscribe to our podcast and leave us feedback! References: Lopez Valle RG, Godoy FL. Neostigmine for acute colonic pseudo-obstruction: a meta-analysis. Annals of Medicine and Surgery. 2014; 3: 60-64 Bernardi MP, et al. Acute and chronic pseudo-obstruction: a current update. ANZ J Surg. 2015; 85: 709-714 Vogel JD, et al. Clinical practice guidelines for co...
Episode 4- Guidelines on the acute treatment of cerebral edema
May 05, 2020 16:00 - 8 minutes - 5.68 MBIn this episode, we discuss hypertonic saline solutions and mannitol for the treatment of cerebral edema in a variety of clinical settings. Please remember to subscribe to our podcast and leave us a comment to enter a drawing for your chance to win a gift! References: Cook, AM, et al. Guidelines for the acute treatment of cerebral edema in neurocritical care patients. Neurocrit care. 2020. https://doi.org/10.1007/s12028-020-00959-7 Mesghali E, at al. Safety of peripheral line administrati...
Episode 3- "Vitamin D": Droperidol for agitation in the ER
May 01, 2020 14:00 - 6 minutes - 4.29 MBIn this episode, we discuss the use of droperidol for the treatment of agitation in the ER setting. Please remember to subscribe to our podcast and leave us a comment! References: Knott JC, et al. Randomized clinical trial comparing intravenous midazolam and droperidol for sedation of the acutely agitated patient in the emergency department. Ann Emerg Med. 2006; 47: 61-67 Isbister GK, et al. Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute b...