This Week in Virology
665 episodes - English - Latest episode: 1 day ago - ★★★★★ - 2K ratingsThis Week in Virology is a netcast about viruses - the kind that make you sick.
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Episodes
TWiV 971: Another year is viral
January 01, 2023 05:00 - 1 hour - 65.6 MBIn the first epitope of 2023, TWiV reviews our coverage of virology in 2022, including favorite story arcs, episodes, show titles, and much more. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Our favorite 2022 virology stories: •Vincent: Paul Offit on bivalent boosters (TWiV 917, 942, Special) •Dickson: Interviews with Pau...
TWiV 970: Clinical update with Dr. Daniel Griffin
December 31, 2022 05:00 - 51 minutes - 30.2 MBIn his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roommate-to-roommate transmission of severe SARS-CoV-2, clinical validation of a novel T-Cell receptor...
TWiV 969: Carl Zimmer on COVID-19
December 28, 2022 05:00 - 48 minutes - 28.1 MBCarl Zimmer visits the Incubator to record a wide-ranging conversation about COVID-19, including origins, vaccines, public health responses, and impact on society. Host: Vincent Racaniello Guest: Carl Zimmer Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]
TWiV 968: A spillover waiting in the wings
December 25, 2022 05:00 - 1 hour - 63 MBTWiV reviews eukaryotic viruses recovered from ancient permafrost, a mistake made by scientists on Omicron origins, and close relatives of MERS-CoV from bats that bind ACE2 for entry into cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Positions...
TWiV 967: Clinical update with Dr. Daniel Griffin
December 24, 2022 05:00 - 50 minutes - 29.5 MBIn his weekly clinical update Dr. Griffin discusses how immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection, prevalence of SARS-CoV-2 and influenza coinfection and clinical characteristics among children and adolescents aged <18 years who were hospitalized or died with Influenza, WHO estimates of excess mortality associated with the COVID-19 pandemic, reconsideration of anti-nucleocapsid IgG antibody as a marker of SARS-CoV-2 infection po...
TWiV 966: 1918 influenza with Jeffery Taubenberger
December 23, 2022 05:00 - 1 hour - 64.6 MBVincent travels to the NIH campus to speak with Jeffery Taubenberger about his career, the 1918 influenza pandemic, deciphering the genome sequence of the virus from tissues of disease victims and using it to rescue infectious virus. Host: Vincent Racaniello Guest: Jeffery Taubenberger Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Influ...
TWiV 965: Asking Esper Kallas for some I.D.
December 18, 2022 05:00 - 1 hour - 54.7 MBBrazilian infectious diseases physician Esper Kallas returns to TWiV to discuss the state of viral diseases in his country, including those cause by Zika, dengue, and yellow fever viruses, MPOX, and SARS-CoV-2. Hosts: Vincent Racaniello and Alan Dove Guest: Esper Kallas Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV International Scienti...
TWiV 964: Clinical update with Dr. Daniel Griffin
December 17, 2022 05:00 - 42 minutes - 24.5 MBIn his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by pare...
TWiV 963: Feline coronavirus with Gary Whittaker
December 14, 2022 05:00 - 53 minutes - 31 MBVincent travels to Cornell University to speak with Gary Whittaker about regulation by proteolytic processing of the fusion activity of the spike protein of SARS-CoV-2, and feline coronavirus transmission, replication and disease. Hosts: Vincent Racaniello Guest: Gary Whittaker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode SARS-CoV-2 spike and its furin cleavage site (Lancet Microbe) TMPRSS2 inhibitor blocks SARS-Co...
TWiV Special: Bivalent boosters with Paul Offit
December 12, 2022 05:00 - 30 minutes - 17.8 MBPaul Offit returns to TWiV to discuss why the bivalent booster dosing story should be a cautionary tale of how not to move forward in this pandemic. Hosts: Vincent Racaniello and Rich Condit Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Antibody responses to bivalent booster (bioRxiv) Immunogenicity of bivalent vaccine (bioRxiv) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees ...
TWiV 962: Chiara Mingarelli takes the pulse of the universe
December 11, 2022 05:00 - 1 hour - 65.6 MBAstrophysicist Chiara Mingarelli joins TWiV to discuss her career and her work using pulse timing arrays to study the gravitational wave background, ripples in the fabric of spacetime that are caused by events such as the merging of black holes. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Guest: Chirara Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a ...
TWiV 961: Clinical update with Dr. Daniel Griffin
December 10, 2022 05:00 - 27 minutes - 16.3 MBIn his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals, sensitivity of anti-SARS-CoV-2 nucleocap...
TWiV 960: Getting funky with Dan Wilson
December 04, 2022 05:00 - 2 hours - 74.7 MBDan Wilson of Debunk the Funk joins TWiV to explain why he decided to take on science misinformation and how he critiques people who promulgate incorrect information. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Guest: Dan Wilson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV International Scientific Coo...
TWiV 959: Clinical update with Dr. Daniel Griffin
December 03, 2022 05:00 - 48 minutes - 28 MBIn his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preter...
TWiV 958: Pass the RNA and have some venison pi
November 27, 2022 05:00 - 1 hour - 62.6 MBThe TWiV team reveals a variant SARS-CoV-2 that emerged in deer with deer-to-human transmission, and hybrid virus particles produced by co-infection with influenza virus and respiratory syncytial virus particles. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code ...
TWiV 957: Clinical update with Dr. Daniel Griffin
November 26, 2022 05:00 - 43 minutes - 25.3 MBIn his weekly clinical update Dr. Griffin discusses human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks, changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States, updates on COVID-19–related mortality, impact of community masking on COVID-19, effectiveness of the COVID-19 vaccines against hospitalization with Omicron sub-lineages BA.4 and BA.5 in England, cardiovascular outcomes after T...
TWiV 956: A domesticated viral envelope with Cedric Feschotte and John Anthony Frank
November 20, 2022 05:00 - 1 hour - 58.2 MBCedric and John join TWiV to discuss their research showing that a human protein derived from an ancient retrovirus infection can protect against infection by other retroviruses. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guest: Cedric Feschotte and John Anthony Frank Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV Cedric ...
TWiV 955: Clinical update with Dr. Daniel Griffin
November 19, 2022 05:00 - 46 minutes - 27.3 MBIn his weekly clinical update Dr. Griffin discusses the four things to know about RSV, the burden of respiratory syncytial virus in healthy term-born infants in Europe, the diagnostic accuracy of rapid diagnostic tests for Ebola virus disease, evaluating the accuracy of self-collected swabs for the diagnosis of monkeypox, tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations, acute and postacute sequelae associated with SARS-CoV-2 reinfection, clinical c...
TWiV 954: Speculating sarbecovirus spillovers with Michael Letko
November 13, 2022 17:00 - 1 hour - 63.5 MBMichael Letko joins TWiV to discuss his research on understanding cell receptors required for sarbecovirus entry, including an ACE2-dependent isolate from Russian bats that is resistant to vaccine-induced antibodies. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Michael Letko Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (V...
TWiV 953: Clinical update with Dr. Daniel Griffin
November 12, 2022 05:00 - 54 minutes - 31.9 MBIn his weekly clinical update Dr. Griffin discusses high demand for Amoxicillin causing shortages amid child RSV surge, epidemiologic and clinical features of children and adolescents aged <18 years with monkeypox, low risk of SARS-Cov-2 transmission by fomites, nucleocapsid antigenemia is a marker of acute SARS-CoV-2 infection, impact of community masking on COVID-19, protection against Omicron from vaccination and previous infection in a prison system, Nirmatrelvir and the risk of post-ac...
TWiV 952: Jake Scott put the ID in COVID-19
November 06, 2022 04:00 - 1 hour - 60.2 MBInfectious Disease physician Jake Scott joins TWiV to provide a west coast clinical perspective on the evolution of the COVID-19 pandemic with respect to the impact of vaccines, antivirals, variants of concern and mortality. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guest: Jake Scott Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with p...
TWiV 951: Clinical update with Dr. Daniel Griffin
November 05, 2022 04:00 - 49 minutes - 28.9 MBIn his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses,...
TWiV 950: Prion diseases with Richard Knight
October 30, 2022 04:00 - 43 minutes - 25.3 MBFrom the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Richard Knight about prion diseases and the outbreak of bovine spongiform encephalitis that led to cases of variant Creutzfeldt-Jakob disease in humans. Host: Vincent Racaniello Guest: Richard Knight Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode National CJD Research and Surveillance Unit Clinical diagnosis of huma...
TWiV 949: Clinical update with Dr. Daniel Griffin
October 29, 2022 04:00 - 45 minutes - 26.3 MBIn his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and rein...
TWiV 948: Breathless with David Quammen
October 23, 2022 04:00 - 1 hour - 63.1 MBDavid Quammen returns to TWiV to discuss how he wrote his new book ‘Breathless’, a story about the science and the scientists behind the race to understand the pandemic coronavirus SARS-CoV-2. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guest: David Quammen Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Boston Quammens (TWiV 408) Breathless by David Quammen Spillover by David Quammen...
TWiV 947: Clinical update with Dr. Daniel Griffin
October 22, 2022 04:00 - 33 minutes - 19.8 MBIn his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWi...
TWiV 946: Poo versus flu
October 16, 2022 04:00 - 1 hour - 63 MBAngela Mingarelli joins TWiV to discuss whether the gut microbiota of bats confers tolerance to influenza virus infection in mice, and primate hemorrhagic fever-causing arteriviruses that can reproduce in human cells and might be capable of infecting humans. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ...
TWiV 945: Clinical update with Dr. Daniel Griffin
October 15, 2022 04:00 - 44 minutes - 25.9 MBIn his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with...
TWiV 944: Hacking through Borneo with Kathryn Hanley
October 09, 2022 04:00 - 1 hour - 65.6 MBKathryn Hanley joins TWiV to discuss her career and the research in her laboratory on the molecular biology, evolution and ecology of emerging RNA viruses and their insect vectors. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guest: Kathryn Hanley Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) One bite is ...
TWiV 943: Clinical update with Dr. Daniel Griffin
October 08, 2022 04:00 - 42 minutes - 24.8 MBIn his weekly clinical update Dr. Griffin discusses high points of the multi-national monkeypox outbreaks, monkeypox virus genome mutations, possible occupational infection of healthcare workers with monkeypox virus, rates of monkeypox cases by vaccination status, protection of SARS-CoV-2 infection against reinfection, Paxlovid significantly reduces COVID-19 hospitalizations and deaths, and rebound in COVID19 with and without Paxlovid treatment. Subscribe (free): Apple Podcasts, Google Pod...
Public Health with Laurie Garrett: Wastewater Testing
October 04, 2022 19:40 - 1 hour - 35.2 MBLaurie Garrett discusses the role of wastewater testing in public health and her idea of a device that could be used by anyone to analyze water samples. This podcast is not an episode of TWiV, but I thought it would be of interest to listeners. Laurie Garrett and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Coliform testing of water in Florid...
TWiV 942: Omicron boosters with Paul Offit
October 02, 2022 04:00 - 1 hour - 65.6 MBPaul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position a...
TWiV 941: Clinical update with Dr. Daniel Griffin
October 01, 2022 04:00 - 50 minutes - 29.2 MBIn his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vaccinated and unvaccinated household contacts during replacement of delta with omicron variant, brea...
TWiV 940: Eddie Holmes in on viral origins
September 28, 2022 04:00 - 1 hour - 53.1 MBEddie Holmes joins TWiV to discuss his role in the first release of the SARS-CoV-2 genome sequence, what really happened during the infamous Fauci teleconference, and evidence that the virus came from Nature and not from a lab. Hosts: Vincent Racaniello and Dickson Despommier Guest: Eddie Holmes Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-s...
TWiV 939: From lizards to Lassa with Tom Monath
September 25, 2022 04:00 - 2 hours - 69.7 MBTom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Tom Monath Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t...
TWiV 938: Clinical update with Dr. Daniel Griffin
September 24, 2022 04:00 - 53 minutes - 30.8 MBIn his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b2 against Omicron, awareness and use of SARS-CoV-2 antivirals, comparable outcomes for Bebtelovi...
TWiV 937: Pediatric hepatitis with Emma Thomson
September 18, 2022 04:00 - 1 hour - 35.3 MBFrom the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Emma Thomson about the recent outbreak of pediatric hepatitis of unknown etiology and the finding that it is linked to infection by adenovirus-associated virus 2. Hosts: Vincent Racaniello Guest: Emma Thomson Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Thomson laboratory Emma on TWiV 188 and TWiV 341 AAV2-ass...
TWiV 936: Clinical update with Dr. Daniel Griffin
September 17, 2022 04:00 - 52 minutes - 30.3 MBIn his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, effectiveness of COVID-19 v...
TWiV 935: Mobile DNA with Cedric Feschotte
September 11, 2022 04:00 - 1 hour - 48.1 MBVincent travels to Cornell University to speak with Cedric about his career and his research on mobile genetic elements such as transposons and endogenous viruses and how they have shaped the evolution of nearly all organisms. Hosts: Vincent Racaniello Guest: Cedric Feschotte Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Feschotte laboratory Field guide to transposable elements (Ann Rev Genetics) Timestamps by Jol...
TWiV 934: Clinical update with Dr. Daniel Griffin
September 10, 2022 04:00 - 52 minutes - 30.5 MBIn his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and env...
TWiV 933: Island-hopping bats
September 04, 2022 04:00 - 1 hour - 62.1 MBTWiV discusses a new henipavirus from fruit bats in Madagascar, and attenuation of SARS-CoV-2 Omicron disease in mice caused by genome mutations outside of the spike protein coding region. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Beijerinck virology prize (KNAW) Nipah virus vaccine (TWiV 6...
TWiV 932: Clinical update with Dr. Daniel Griffin
September 03, 2022 04:00 - 49 minutes - 28.9 MBIn his weekly clinical update Dr. Griffin discusses vaccine effectiveness against influenza illness in children, clinical manifestations of infection with poliovirus, spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice, concordance of SARS-CoV-2 results in self-collected nasal swabs vs swabs collected by health care workers in children and adolescents, probable animal-to-human transmission of SARS-CoV-2 causing a pet shop-related outbreak, laboratory-confir...
TWiV 931: Driven to immunodistraction
August 28, 2022 04:00 - 2 hours - 69.9 MBTWiV reviews the genetic characterization of a new strain of type 2 oral polio vaccine and its implications for eradication, and how a polymorphism in humans comprising a single amino acid change in an antibody molecule regulates vaccine elicitation of broadly neutralizing antibodies against influenza virus HA. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWi...
TWiV 930: Clinical update with Dr. Daniel Griffin
August 27, 2022 04:00 - 48 minutes - 28.1 MBIn his weekly clinical update Dr. Griffin discusses antibody response against nonpoliovirus enteroviruses, clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain, object and surface contamination with monkeypox virus, monkeypox virus infection in humans across 16 countries, clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection, compassionate use of Tecovirimat for the treatment of monkeypox infection, monit...
TWiV 929: Empathyology with Andy Slavitt
August 21, 2022 04:00 - 2 hours - 69.3 MBAndy Slavitt joins TWiV to discuss his book, Preventable and how failures in leadership, politics, and selfishness doomed the U.S. response to SARS-CoV-2. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Guest: Andy Slavitt Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode In the Bubble podcast Preventable (Amazon) Letters read on TWiV 929 Timestamps by Jolene. Thanks! Weekly Pick...
TWiV 928: Clinical update with Dr. Daniel Griffin
August 20, 2022 04:00 - 41 minutes - 24.2 MBIn his weekly clinical update Dr. Griffin discusses the public health response to a polio case in a unvaccinated NY state resident, human to dog transmission of monkeypox virus, Tecovirimat and the treatment of monkeypox, detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium, what to do if you are exposed to SARS-CoV-2 and isolation and precautions for people with COVID-19, risk of SARS-CoV-2 infection in health care workers, effectiveness ...
TWiV 927: Merchlinsky vs monkeypox
August 14, 2022 04:00 - 1 hour - 63.6 MBMichael Merchlinsky joins TWiV to discuss the development of two smallpox antiviral drugs and two smallpox vaccines and their uses during the monkeypox outbreak. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Michael Merchlinsky Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Michael on Anything but academic (TWiM 145) Development of Tecoviromat (TPOXX) (Antiviral Res) Use of J...
TWiV 926: Clinical update with Dr. Daniel Griffin
August 13, 2022 04:00 - 40 minutes - 23.7 MBIn his weekly clinical update Dr. Griffin discusses guidance for prevention and treatment of monkeypox, post-infectious symptoms among children and adolescents, profiling post-infectious syndromes of different variants, comparison of vaccine Ankara vs intradermal routes of administration, infection in vaccinated individuals treated with or without PAXLOVID, duration of symptoms with positive rapid antigen after infection, epidemiologic characteristics of monkeypox, and sequelae of post-acute...
TWiV 925: First kisses and second doses
August 07, 2022 04:00 - 1 hour - 59.4 MBTWiV discusses monkeypox virus, poliovirus in NY, Marburg virus in Ghana, ancient herpes simplex virus type 1 genomes, and immunogenicity of different combinations of SARS-CoV-2 vaccines. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode How monkeypox virus spreads (CDC) Vaccination against monkeypox virus (CDC) Monkeypox case trends...
TWiV 924: TWiV clinical update with Dr. Daniel Griffin
August 06, 2022 04:00 - 46 minutes - 27 MBIn his weekly clinical update Dr. Griffin discusses Tecovirimat for treatment of monkeypox, the safety and acceptance of vaccination after multisystem inflammatory syndrome, variants in solid organ transplant recipients, masks for prevention of respiratory virus infections, pre-exposure prophylaxis with Evusheld, the association between Evusheld administration and infection, if repeat administration of casirivimab and imdevimab is well-tolerated, viral and symptom rebound in untreated infec...