Latest Efficacy Podcast Episodes
Analysis of vertebral augmentation practice patterns update. The farewell to JNIS editor Robert Tarr
JNIS Podcast - January 03, 2017 12:30 - 18 minutes ★★★★★ - 14 ratingsIn this farewell podcast of the JNIS Editor-in-Chief, Robert Tarr talks vertebral augmentation practice with Associate Editor Joshua Hirsch and Ronil Chandra. Dr J A Hirsch, from the Massachusetts General Hospital, Harvard Medical School, USA, and Dr R V Chandra, from the Interventional Neurorad...
Type of general anesthesia effects on endovascular management of acute ischemic stroke
JNIS Podcast - October 27, 2016 17:50 - 14 minutes ★★★★★ - 14 ratingsIn this podcast, Andrew Kofke, from the Departments of Anesthesiology and Critical Care and Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA, reveals the details of his JNIS Editor's Choice paper published in the November 2016 issue. The study concludes th...
Posterior cranial fossa arteriovenous malformations are more prone to feeder vessel aneurysms
JNIS Podcast - October 04, 2016 14:39 - 10 minutes ★★★★★ - 14 ratingsIn this podcast, the Editor-in-Chief of JNIS, Robert Tarr, is joined by Ali Alaraj, the corresponding author of the study, "Increased prevalence and rupture status of feeder vessel aneurysms in posterior fossa arteriovenous malformations". Dr Alaraj, from the Department of Neurosurgery, Neuropsy...
The low-profile visualized intraluminal support device use on wide-necked intracranial aneurysms
JNIS Podcast - September 06, 2016 12:26 - 6 minutes ★★★★★ - 14 ratingsIn this podcast, the Editor-in-Chief of JNIS, Robert Tarr, is joined by David Fiorella, the corresponding author of the study, "Final results of the US humanitarian device exemption study of the low-profile visualized intraluminal support (LVIS) device". Dr Fiorella, from the Department of Neuro...
GRAFT reduces potential flow diverter malapposition and occasional acute thrombus formation
JNIS Podcast - July 14, 2016 17:06 - 10 minutes ★★★★★ - 14 ratingsIn this podcast, Dr Robert Tarr interviews Dr Matthew Gounis and Dr Ajit Puri on their latest study, "Grading of Regional Apposition after Flow-Diverter Treatment (GRAFT): a comparative evaluation of VasoCT and intravascular OCT". GRAFT is a semi-automated image post-processing software, which ...
Arteriovenous malformation embocure score
JNIS Podcast - June 28, 2016 16:03 - 14 minutes ★★★★★ - 14 ratingsIn this podcast, Dr Demetrius Lopes tells Robert Tarr, the Editor of JNIS, the details of the study "Arteriovenous malformation embocure score: AVMES". Demetrius Lopes, a neuroendovascular surgeon at Rush University Medical Center, Chicago, Illinois, USA, is the corresponding author of this stud...
Three-dimensional printing of anatomically accurate patient specific intracranial aneurysm models
JNIS Podcast - June 06, 2016 17:21 - 13 minutes ★★★★★ - 14 ratingsIn this podcast, the Editor of JNIS, Robert Tarr, talks to Christof Karmonik, from the Houston Methodist Research Institute, USA, about the details of the study "Three-dimensional printing of anatomically accurate patient specific intracranial aneurysm models". The research concluded that the 3D...
Endovascular Stroke Therapy: early emergency arrivals effects on collaterals, infarcts and outcomes
JNIS Podcast - May 19, 2016 19:35 - 14 minutes ★★★★★ - 14 ratingsIn this podcast, Dr David Liebeskind, explains the details of the paper "Early arrival at the emergency department is associated with better collaterals, smaller established infarcts and better clinical outcomes with endovascular stroke therapy: SWIFT study". Dr David Liebeskind, from the Neurov...
Stroke treated with mechanical thrombectomy: outcomes of prior use of intravenous thrombolysis
JNIS Podcast - April 19, 2016 16:12 - 38 minutes ★★★★★ - 14 ratingsWith multiple RCTs demonstrating clear benefit of mechanical thrombectomy in ELVO, the question of best approach to patients eligible for simultaneous treatment with IV TPA and mechanical thrombectomy has been debated. Dr. Hirsch interviews Drs. Leslie-Mazwi and Weber after their instructive pap...
Catheter based selective hypothermia reduces stroke volume during focal cerebral ischemia in swine
JNIS Podcast - April 01, 2016 11:27 - 11 minutes ★★★★★ - 14 ratingsIn this podcast, Dr Thomas Mattingly explains the details of this study conducted in swines and which gives insights into wether endovascular selective hypothermia can provide neuroprotection within time frames relevant to acute ischemic stroke treatment. Read the full article here: http://jnis....
Predictors of poor outcome despite recanalization: a regression analysis of the NASA registry
JNIS Podcast - March 01, 2016 17:36 - 14 minutes ★★★★★ - 14 ratingsIn this podcast, Italo Linfante, Miami Cardiac and Vascular Institute and Neuroscience Center, Baptist Hospital, Miami, USA, tells JNIS’ Editor Robert Tarr, the details of his study “Predictors of poor outcome despite recanalization: a multiple regression analysis of the NASA registry”. To acces...
Raymond-Roy Occlusion Classification of intracranial aneurysms treated with coil embolization
JNIS Podcast - January 29, 2016 17:06 - 10 minutes ★★★★★ - 14 ratingsIn this podcast we find the details of the study "An update to the Raymond-Roy Occlusion Classification of intracranial aneurysms treated with coil embolization". Professor Robert Tarr interviews Justin Mascitelli, the author of the article, which can be read here: http://goo.gl/9IEX8L.
Critical assessment of the morbidity associated with ruptured cerebral arteriovenous malformations
JNIS Podcast - January 12, 2016 11:23 - 13 minutes ★★★★★ - 14 ratingsIn this podcast Dr Robert Tarr talks to Dr Michael Chen about his editors choice paper "Critical assessment of the morbidity associated with ruptured cerebral arteriovenous malformations". They discuss the reasons for undertaking the study, the controversy surrounding the ARUBA trial and the pos...
Healing of aneurysm: a comparison of gene expressions
JNIS Podcast - December 02, 2015 11:49 - 11 minutes ★★★★★ - 14 ratingsWhat understanding do we have of the rupture risk and healing following aneurysm treatment? Robert Tarr interviews Ram Kardivel, of the Neuroradiology Research Laboratory, Mayo Clinic, USA, on the main conclusions of her study "Gene expression comparison of flow diversion and coiling in an expe...
Aneurysm permeability following coil embolization: Packing density and coil distribution
JNIS Podcast - October 08, 2015 11:48 - 12 minutes ★★★★★ - 14 ratingsIn this podcast Dr Robert Tarr talks to Dr Matt Gounis and his team Dr Juyu Chueh and Dr Srinivasan Vedantham about their editors choice paper. In this podcast they discuss their methodology and the drawbacks of this kind of study. Full paper >> http://jnis.bmj.com/content/7/9/676.full
Incidence and morbidity of craniocervical arterial dissections
JNIS Podcast - October 06, 2015 13:40 - 12 minutes ★★★★★ - 14 ratingsIn this podcast Dr Robert Tarr speaks to Dr Ali Seifi about his recent paper that was selected as editors choice. This podcast covers the differences in mortality and patient outcome between endovascular coiling and surgical clipping and discusses possible chances for a future aneurysm registry. ...
The trials and tribulations of peer review
JNIS Podcast - June 30, 2015 16:21 - 30 minutes ★★★★★ - 14 ratingsBias and peer review are of universal importance to all those that produce scholarly work. Fiona Godlee and Rob Tarr, editors in chief of The BMJ and JNIS respectively, share their insights and experience on these highly topical issues with Joshua Hirsch. Read the related paper: http://jnis.bmj...
Value based healthcare and the specialist
JNIS Podcast - May 13, 2015 13:42 - 36 minutes ★★★★★ - 14 ratingsThe system of healthcare delivery in the United States is in the midst of a meaningful transition. Traditional fee for service paradigms are moving towards what has been termed value-based approaches. Doctors Joshua HIrsch, Geraldine Mcginty and Greg Nicola examine recent developments and discus...
The MRClean trial
JNIS Podcast - February 02, 2015 16:48 - 26 minutes ★★★★★ - 14 ratingsOn Dec 17th 2014, the NEJM published the results of MR CLEAN; a Dutch study comparing patients treated with intra-arterial thrombolysis to those of a medically managed cohort. The design of this trial was ingenious; focusing attention on patients who appeared to have failed intravenous thromboly...
Endovascular treatment for large vessel stroke
JNIS Podcast - January 14, 2015 14:52 - 39 minutes ★★★★★ - 14 ratingsWith advances in device design, patient selection paradigms and other elements of treatment, the neuroendovascular approach to acute ischemic stroke has made great strides forward. In this podcast, Dr Joshua Hirsch interviews Dr Brijesh Mehta on how the implementation of operational improvement...
ASPECTS decay during inter-facility transfer predicts patient outcomes
JNIS Podcast - January 02, 2015 14:52 - 8 minutes ★★★★★ - 14 ratingsPretreatment Alberta Stroke Program Early CT Scores (ASPECTS) is associated with clinical outcomes. The rate of decline between subsequent images, however, may be more predictive of outcomes as it integrates time and physiology. A paper published in the January issue of JNIS retrospectively look...
Unruptured intracranial aneurysms conservatively followed with serial CT angiography
JNIS Podcast - December 17, 2014 12:11 - 13 minutes ★★★★★ - 14 ratingsCould morphology and growth predict rupture? Despite several landmark studies, the natural history of unruptured intracranial aneurysms (UIA) remains uncertain. Rob Tarr talks to William Mehan, Division of Neuroradiology, Massachusetts General Hospital, about his paper which aimed to identify o...
Admission neutrophil–lymphocyte ratio predicts 90 day outcome after endovascular stroke therapy
JNIS Podcast - November 05, 2014 14:23 - 11 minutes ★★★★★ - 14 ratingsImmune dysregulation influences outcome following acute ischemic stroke (AIS). Admission white blood cell counts are routinely obtained, making the neutrophil–lymphocyte ratio (NLR) a readily available biomarker of the immune response to stroke. With colleagues Taura Barr, WVU Prevention Resear...
Endovascular recanalization of complete subacute to chronic atherosclerotic occlusions
JNIS Podcast - October 10, 2014 14:21 - 16 minutes ★★★★★ - 14 ratingsSymptomatic subacute/chronic large artery intracranial occlusive disease represents a common medical dilemma. A recent JNIS paper reports a multicenter experience of endovascular recanalization of intracranial atherosclerotic occlusions refractory to medical therapy. Robb Tarr talks to co-author...
Safety and predictors of aneurysm retreatment for remnant intracranial aneurysm
JNIS Podcast - October 01, 2014 12:47 - 19 minutes ★★★★★ - 14 ratingsAneurysmal subarachnoid hemorrhage (SAH) is a rare but devastating form of stroke. Endovascular therapy has been criticized for its higher rate of recanalization and retreatment. The safety and predictors of retreatment are unknown. A recent study in JNIS reports the clinical outcomes, imaging ...
Affordable care 2014: A tale of two boards
JNIS Podcast - August 12, 2014 16:37 - 36 minutes ★★★★★ - 14 ratingsThe Patient Protection and Affordable Care Act (ACA) became law on 23 March 2010. As part of the law, two independent boards were established. The Patient-Centered Outcomes Research Institute embodies national aspirations for employing comparative effectiveness research in healthcare decision-ma...
Flat detector derived parenchymal blood volume maps to estimate cerebral blood volume
JNIS Podcast - July 28, 2014 13:23 - 8 minutes ★★★★★ - 14 ratingsNewer flat panel angiographic detector (FD) systems have the capability to generate parenchymal blood volume (PBV) maps. The ability to generate these maps in the angiographic suite has the potential to markedly expedite the triage and treatment of patients with acute ischemic stroke. David Fi...
Current Procedural Terminology
JNIS Podcast - April 09, 2014 10:05 - 30 minutes ★★★★★ - 14 ratingsUS physicians nearly universally use the CPT coding system. This code set communicates medical, procedural, surgical and diagnostic services and is a critical component of describing the work we do. Drs. Josh Hirsch, Jackie Bello and Raymond Tu are actively involved in the world of physician re...
The ADAPT technique in the clinic: A direct aspiration first pass technique for stroke thrombectomy
JNIS Podcast - April 07, 2014 16:27 - 17 minutes ★★★★★ - 14 ratingsThe development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. In a paper in May's JNIS, Aquilla Turk, Department of Radiology, Medical University of South Carolina, ad colleagues, report their initial results with a new technique utilizing...
Evidence based neurointervention
JNIS Podcast - March 20, 2014 14:47 - 30 minutes ★★★★★ - 14 ratingsDrs. Hirsch, Meyers and Jayaraman discuss the evolving and at times complex role of Evidence Based Medicine (EBM) in contemporary neurointerventional practice. The discussants contrast EBM with Comparative Effectiveness Research and the role it plays in coverage decisions. The podcast directly...
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