Latest Crispr Podcast Episodes

Pandemics & Pathogens Past & Present artwork

Stable vs Radioactive Ep. 5

Pandemics & Pathogens Past & Present - February 08, 2022 00:54 ★★★★★ - 3 ratings
Some isotopes are stable. Some are radioactive. What’s the difference? 12 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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What’s an Isotope? Ep. 4

Pandemics & Pathogens Past & Present - February 08, 2022 00:50 ★★★★★ - 3 ratings
How isotopes are defined. Examples. 9 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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Atoms. Ep. 3

Pandemics & Pathogens Past & Present - February 08, 2022 00:47 ★★★★★ - 3 ratings
How atoms are constructed. 6 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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The Standard Model. Ep. 2

Pandemics & Pathogens Past & Present - February 07, 2022 00:57 ★★★★★ - 3 ratings
A review of what particles make up the universe. 6 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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It’s About Isotopes. Ep. 1

Pandemics & Pathogens Past & Present - February 07, 2022 00:07 ★★★★★ - 3 ratings
Why isotopes? An introduction to the series. 4 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

Noah and the Nephilim // Pastor Gene Pensiero artwork

Prophecy Update #661 – Skullduggery

Noah and the Nephilim // Pastor Gene Pensiero - July 04, 2021 20:38 - 5 minutes ★★★★ - 33 ratings
In Genesis 6, fallen angels married and mated with human women. Their offspring were giants called in the Bible Nephilim. (Pastor Gene Pensiero)

Essentials of CRISPR-based Animal Models in Drug Discovery artwork

What is so different about CRISPR Founder breeding?

Essentials of CRISPR-based Animal Models in Drug Discovery - December 16, 2020 20:26 - 28 minutes
Gretchen Kusek, PhD, Associate Director Scientific Services, and Bart Smits, PhD, Manager Genetic Sciences and Compliance, discuss the key considerations when breeding gene-edited animals using CRISPR, particularly in the context of mosaicism. See acast.com/privacy for privacy and opt-out infor...

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Legal Considerations When Choosing a Genetic Modification Technology to Generate an Animal Model

Essentials of CRISPR-based Animal Models in Drug Discovery - December 02, 2020 23:15 - 17 minutes
Gretchen Rice, PhD, JD, Vice President and General Counsel, and Mark Johnson, PhD, Scientific Program Manager, discuss the licensing considerations that go into using CRISPR and other gene editing platforms to create genetically engineered animal models. See acast.com/privacy for privacy and op...

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Choosing the Best Genetic Modification Technology to Generate an Animal Model

Essentials of CRISPR-based Animal Models in Drug Discovery - November 05, 2020 21:48 - 19 minutes
Evert-Jan Uringa and Dominique Bröehl, Scientific Program Managers with Taconic, discuss how to choose the best genetic modification technology to generate an animal model. See acast.com/privacy for privacy and opt-out information.

Pandemics & Pathogens Past & Present artwork

Special Topic: COVID-19 Vaccines. Ep. 34

Pandemics & Pathogens Past & Present - November 04, 2020 01:12 ★★★★★ - 3 ratings
First I discuss the phases of drug or vaccine trials, then discuss the immune system, and finally outline the various approaches to COVID-19 vaccines (which largely applies to vaccines in general), including very recent advances in types of vaccines, and what the COVID-19 vaccine picture looks li...

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Special Topic: The He Jainku Controversy. Ep. 33

Pandemics & Pathogens Past & Present - November 04, 2020 01:09 ★★★★★ - 3 ratings
What did this guy do? Why was it so controversial? Hint: It involves CRISPR (Ep 31) and adeno-associated retroviruses (Ep 10) and making “designer babies.” 13 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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Special Topic: How Pandemics End. Ep. 32

Pandemics & Pathogens Past & Present - November 04, 2020 01:08 ★★★★★ - 3 ratings
First, I revisit the smallpox vaccine. Then I review a Ted Talk by Alex Rosenthal regarding how pandemics can end via three possible strategies. 12 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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Special Topic: CRISPR. Ep. 31

Pandemics & Pathogens Past & Present - November 04, 2020 01:05 ★★★★★ - 3 ratings
What is it and what is it good for? My prediction, on September 3, 2020, that Emmanuelle Charpentier and Jennifer A. Doudna would win the Nobel Prize. They won on October 7, 2020. 16 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith...

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Malaria. Ep. 30

Pandemics & Pathogens Past & Present - November 04, 2020 01:00 ★★★★★ - 3 ratings
What it is. Discovery of malaria. It’s life cycle. Connection to sickle cell anemia. Historical outbreaks. The Vampire of Lugano (vampires again!). Link between malaria and slavery in America? Current situation. World Mosquito Day? 18 min Pandemics & Pathogens Past & Present Podcastchemsmith1@gma...

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Tuberculosis. Ep. 29

Pandemics & Pathogens Past & Present - November 03, 2020 18:48 ★★★★★ - 3 ratings
Deadly stats. What it is. How it works. “Consumption.” Drug-resistant TB. Historical outbreaks. TB and vampires? Sanitariums. Vaccine. The “romantic disease.” Famous people who had TB. 18 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timc...

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Measles. Ep. 28

Pandemics & Pathogens Past & Present - November 03, 2020 01:20 ★★★★★ - 3 ratings
What it is and how it works. The measles vaccine. Anti-vaccination sentiment. The origin of measles and historical outbreaks. 15 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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Typhus & How Bacteria Work. Ep. 27

Pandemics & Pathogens Past & Present - November 03, 2020 01:17 ★★★★★ - 3 ratings
Types of typhus. Symptoms. I then swerve into a discussion of how bacteria work. Then back to typhus: How it works. Is there a vaccine? Historical outbreaks. Typhus in literature and on television. Anne Frank. 12 min Pandemics & Pathogens Past & Present [email protected] ...

Pandemics & Pathogens Past & Present artwork

2014-2016 West African Ebola Epidemic. Ep. 26

Pandemics & Pathogens Past & Present - November 03, 2020 01:15 ★★★★★ - 3 ratings
It’s origin. Stats. Ebola in the US and political ramifications. About the virus: symptoms & how it works. Vaccine development. 14 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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2009 “Swine Flu” and the Evolution of Flu Strains. Ep. 25

Pandemics & Pathogens Past & Present - November 03, 2020 01:13 ★★★★★ - 3 ratings
Swine flu details & stats. Why called Swine Flu? Barack Obama’s response & criticism. Also, how did flu viruses evolve? What flu strains existed over the decades & where did they come from? How do new strains come about? Finally, I go through the whole evolution of flu strains from 1918 Spanish F...

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SARS and MERS. Introduction to Coronaviruses. Ep. 24

Pandemics & Pathogens Past & Present - November 03, 2020 01:11 ★★★★★ - 3 ratings
The facts of the SARS & MERS outbreaks. Responses to the threats. What are coronaviruses? 17 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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HIV/AIDS Part 2. Ep. 23

Pandemics & Pathogens Past & Present - November 03, 2020 00:12 ★★★★★ - 3 ratings
Virology of AIDS (how it infects). G. W. Bush’s AIDS relief program. HIV drugs. ART (anti-retroviral therapy). Work on HIV vaccines – why so difficult. “Cured” patients. HIV-denialist Peter Duesberg. The work of Robert Gallo and Luc Montagnier. 15 min Pandemics & Pathogens Past & Present Podcastc...

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HIV/AIDS Part 1. Ep. 22

Pandemics & Pathogens Past & Present - November 01, 2020 00:46 ★★★★★ - 3 ratings
Symptoms. Treatment. Origin. History of cases from the 1970’s. Politics/Ronald Reagan. AIDS organizations. Ryan White. Other famous victims. Statistics. 15 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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1968 “Hong Kong Flu.” Ep. 21

Pandemics & Pathogens Past & Present - November 01, 2020 00:41 ★★★★★ - 3 ratings
First I mention a 1348 plague-related riot in Germany. Then I talk about how the 1918 flu might have changed history when President Woodrow Wilson came down with it. Then I turn to the 1968 flu. How did it arise? Who was affected? What about Woodstock? 11 min Pandemics & Pathogens Past & Present ...

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1957 “Asian Flu.” Ep. 20

Pandemics & Pathogens Past & Present - November 01, 2020 00:37 ★★★★★ - 3 ratings
First I try to guess at what pathogens killed the most people in all of history. (I revise this in a later episode.) Also a little cholera story. Then the story of the Asian Flu. About flu subtypes and the origin of the Asian Flu. 13 min Pandemics & Pathogens Past & Present Podcastchemsmith1@gmai...

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Polio Part 2. Vaccines. Ep. 19

Pandemics & Pathogens Past & Present - November 01, 2020 00:26 ★★★★★ - 3 ratings
The development of them (drama!). Koprowski’s live attenuated vaccine vs. Salk’s dead-virus injectable vaccine. How Koprowski’s vaccine was made (wild science). Experimenting on disabled or prison poluations (not cool). Roosevelt and the March of Dimes. The Koprowski/Sabin sugar cube vaccine. Leg...

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Polio Part 1. Ep. 18

Pandemics & Pathogens Past & Present - November 01, 2020 00:22 ★★★★★ - 3 ratings
What is it? How long has it been around? Polio in the 1900’s. President Franklin Roosevelt. Weird early treatments. The Iron Lung. 1950’s outbreaks. 16 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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The 1918 “Spanish Flu.” Ep. 17

Pandemics & Pathogens Past & Present - November 01, 2020 00:13 ★★★★★ - 3 ratings
Why was it called that? How it happened. Who was affected and theories about why. Masks! Social distancing! Snake oil cures. Yes, literally snake oil. 17 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Direct Link to episode

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Pre-1918 Influenza Epidemics. Ep. 16

Pandemics & Pathogens Past & Present - November 01, 2020 00:08 ★★★★★ - 3 ratings
From 5000 B.C. to the 1889 “Russian Flu.” Including the role of Christopher Columbus, and the arrival of the flu in the Americas. Early theories of the causes of flu, and early flu treatments. 17 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagr...

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Smallpox Wrap-up. Ep. 15

Pandemics & Pathogens Past & Present - November 01, 2020 00:04 ★★★★★ - 3 ratings
Where did smallpox come from? How does it infect? What is chickenpox? What is shingles? Timeline of smallpox outbreaks. The end of smallpox. Then again, is it really gone? 16 min Pandemics & Pathogens Past & Present [email protected] @chemsmithInstagram @timcsmith1961 Dir...

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Cholera epidemics from 1817. Ep. 14

Pandemics & Pathogens Past & Present - October 31, 2020 23:40 ★★★★★ - 3 ratings
First, second, and third cholera epidemics. In India, Europe, Russia, and the Americas. What is cholera & how does it work? Its symptoms. Current situation. Miasma, germ theory and the importance of the epidemiological work of John Snow’s observations of the Broad Street epidemic of 1854. 15 min ...

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