Pittsburgh Steelers vs Seattle Seahawks betting picks, predictions and odds for their NFL Week 6 showdown on Sunday, October 17 2021 at 8:15pm ET from Heinz Field in Pittsburgh, Pennsylvania. For the first time in almost a decade, the Seattle Seahawks will start a game without Russell Wilson under center. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert NFL betting analysis on this Sunday Night Football clash between the Steelers and Seahawks. At the time of posting, the WagerTalk Live Odds screen is showing Pittsburgh as a -5 home favorite over Seattle with the over/under sitting at 43 points.