The use of ILE for naproxen toxicosis | VETgirl Veterinary CE Podcasts

In today's VETgirl online veterinary CE podcast, we review Herring et al's recent publication in Journal of Veterinary Emergency Critical Care called "Intravenous lipid emulsion therapy in three cases of canine naproxen overdose." Naproxen, an OTC or prescription human NSAID, has a narrow margin of safety in dogs and cats. As little as 5 mg/kg can result in gastrointestinal distress (e.g., vomiting, diarrhea, etc.) while doses > 10-25 mg/kg can result in acute kidney injury (AKI). Doses > 50 mg/kg can result in central nervous system signs (e.g., tremors, coma, etc.).