The effect of Beta Blockers in Dogs with SAS | VetGirl Veterinary CE Podcasts

In this VETgirl podcast, we review subaortic stenosis (SAS) in dogs, and whether or not the affect of certain cardiac medications (e.g., specifically beta-blockers) affect the overall survival. Subaortic stenosis, more commonly causes SAS, is a common congenital cardiac condition in dogs; it is characterized by a fibrous ring/ridge of tissue below the aortic valve, causing narrowing of this region and secondary pressure overload to the left ventricle. The severity of SAS is determined by the left ventricular-to-aorta pressure gradient (PG), with severe pressure gradients considered to be ≥ 80 mm Hg. In general, the prognosis for mild to moderate SAS is generally considered significantly better than for severe SAS with minimal treatment initiated for the former group. In cases with severe SAS, prior data is limited to a single, small study that reported a 19 month median survival.1,2 As a result, the overall long-term prognosis for severe SAS has been considered to be poor. Treatment of severe SAS has been limited to: