This Week in Evolution
98 episodes - English - Latest episode: 2 months ago - ★★★★★ - 164 ratingsThis Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.
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Episodes
TWiEVO 48: Flipping out with choanos on caffeine
October 31, 2019 01:03 - 1 hour - 54.5 MBNels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Microbial accomplices in multicellularity (TWiEVO 11) Light regulated collective contractility (Science) Image credit Letters read on TWiEVO 48 Time stamps by Jolene. Thanks! Science Picks Nel...
TWiEVO 47: On the origin of beer species
September 19, 2019 21:51 - 1 hour - 53 MBNels and Vincent trace the origins of Saccharomyces cerevisiae strains used to make beer, and find that ales and lagers are made with yeasts that were derived from those used to make European grape wine and Asian rice wine. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Origins of beer yeasts (PLoS Biol) Chateau Jiahu beer Time stamps by Jolene. Thanks! Science Picks Nels - Population fluctuations in 10 ...
TWiEVO 46: Can an old tumor teach us new tricks?
August 31, 2019 18:58 - 1 hour - 53.2 MBNels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Evolution and mutation of canine transmissible cancer (Science) Clam cancers (TWiEVO 17) Sixth modality of infectious disease (PLoS Path) ...
TWiEVO 45: Microbial secrets of mouse-ear cress
July 29, 2019 18:00 - 1 hour - 36 MBAt ASM Microbe in San Francisco, Nels and Vincent meet up with Talia Karasov who reveals that in contrast to agriculture, wild plants are colonized by multiple lineages of pathogenic bacteria. Hosts: Nels Elde and Vincent Racaniello Guest: Talia Karasov Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Talia Karasov in the Bergelson lab Arabidopsis thaliana and Pseudomonas (Cell Host Micr) Time stamps by Jolene. Thanks! Music on TWiEVO is performed...
TWiEVO 44: The enemy of my enemy is my phage
June 27, 2019 16:18 - 1 hour - 37.4 MBAt ASM Microbe in San Francisco, Nels and Vincent meet up with Paul Turner to talk about evolutionary considerations in using bacteriophages to treat infections with antibiotic-resistant bacteria. Hosts: Nels Elde and Vincent Racaniello Guest: Paul Taylor Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Turner Lab at Yale Phage therapy: A renewed approach (Cell Host Microbe) Phage treatment of aortic graft (Evol Med Pub Health) Time stamps by Jol...
TWiEVO 43: Social evolution with a side of shrimp
May 25, 2019 15:05 - 1 hour - 46.6 MBDustin Rubinstein joins Nels and Vincent to discuss coevolution of genome architecture and social behavior, and studying social transitions in sponge-dwelling snapping shrimp. Hosts: Nels Elde and Vincent Racaniello Guest: Dustin Rubinstein Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Co-evolution of genome architecture and social behavior (Trend Ecol Evol) Social transitions in snapping shrimp (Curr Op Insect Sci) Time stamps by Jolene. Than...
TWiEVO 42: Who's who in your genome
April 24, 2019 18:41 - 1 hour - 45.4 MBNels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Denisovan ancestries in Papuans (Cell) Prof Murray Cox Image credit Letters read on TWiEVO 42 Time stamps by Jolene. Thanks! Science Picks Nels- Sydney Brenner - What Genomes Can Tell Us About the Past Vincent- Scientific Communication in a Post-Truth Socie...
TWiEVO 41: Where do baby genes come from?
March 20, 2019 14:56 - 1 hour - 48.6 MBNels and Vincent explore the evolution of new protein-coding genes de novo from nocoding DNA sequences, using the antifreeze protein of northern codfish as a model. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Evolution of antifreeze protein gene in codfish (PNAS) Codfish diversity (Cheng lab) Frankentomatoes (Huff Post) Image credit Time stamps by Jolene. Thanks! Science Picks Nels- Science at Sund...
TWiEVO 40: Eau de bee
February 15, 2019 03:07 - 1 hour - 41.5 MBNels and Vincent move back to reproductive isolation - this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Olfactory receptor gene underlies reproductive isolation (biorXiv) Image credit Time stamps by Jolene. Thanks! Science Picks Nels- Nature Zen: Orchid Bees Are Shiny...
TWiEVO 39: In a Legionella of their own
January 26, 2019 14:18 - 1 hour - 44.6 MBNels and Vincent look at the intracellular bacteria Legionella from an evolutionary perspective: the role of gene acquisition and reshuffling from plants, animals, fungi, and archaea in the emergence of human pathogens. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Over 18,000 effectors in Legionella genome (PNAS) Carmen Buchrieser lab Howard Shuman Science Picks Nels - Science in Film (twitter) Vincent...
TWiEVO 38: Evolving to evolve
December 24, 2018 15:26 - 1 hour - 46.6 MBNels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Inhibiting evolution of antibiotic resistance (Mol Cell) Pushing viruses over the error threshold (virology blog) Image credit Letters read on TWiEVO 38 Science Picks Nels- Science/nature...
TWiEVO 37: A tangled tree on the Quammens
November 17, 2018 19:14 - 1 hour - 52.6 MBDavid Quammen joins Nels and Vincent to talk about his new book, A Tangled Tree, including evolutionary trees, Carl Woese, Lynn Margulis, horizontal gene transfer, and much more. Hosts: Nels Elde and Vincent Racaniello Guest: David Quammen Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO David's website David on TWiV 408, Boston Quammens Axel Erlandson's trees reimagined - Gilroy Gardens Music on TWiEVO is performed by Trampled by Turtles Send y...
TWiEVO 36: All's not quiet on the telomeric front
October 24, 2018 16:00 - 1 hour - 43.5 MBMia joins Nels and Vincent to unravel their finding that the transposons that maintain the ends of chromosomes in Drosophilahave evolved in conflict with the genome. Hosts: Nels Elde and Vincent Racaniello Guest: Mia Levine Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Levine Lab at U Penn Telomere elongation without telomerase (bioRxiv) Letters read on TWiEVO 36 Science Picks Nels - Cinema Science podcast Vincent - Mastodon bones unearthed ...
TWiEVO 35: Strawberry sex chromosomes forever
September 21, 2018 17:26 - 1 hour - 55.5 MBNels and Vincent reveal that female-specific DNA associated with sex in strawberries has repeatedly changed its genomic location, possibly linking new genes with sex. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Jumping sex genes in strawberries (PLoS Biol) Red Queen by Matt Ridley Image credit Letters read on TWiEVO 35 Science Picks Nels - New snailfish and Cloned crayfish Vincent - A PhD Lab Coat Ceremony Listener Picks Steve - Diversity in sim...
TWiEVO 34: You don’t know what you’ve got ‘til it’s PON
August 16, 2018 14:05 - 1 hour - 47.7 MBNels and Vincent discuss how the loss of an enzyme in marine mammals millions of years ago now makes them at risk for neurotoxicity caused by human-made organophosphorous pesticides. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Ancient lossesof paraoxonase I (Science) Big Yellow Taxi (YouTube) Image credit Letters read on TWiEVO 34 Hey farmer farmer put away the chlor-pyri-fus I don’t care about spots on my apples Leave me the manatee and walruses Science...
TWiEVO 33: Fly by virus
July 25, 2018 00:28 - 1 hour - 46.3 MBNels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Virus in fungus in fly (bioRxiv) On a leaf, no one can hear you scream (TWiV 443) Nels gives Benzer Lecture (YouTube) Domestication of fungal fly pathogen (bioRxiv) Sequencing E. muscae genome (10X genomics) Eisen's twitter stream on new iflavirus (Twitter) Science Picks Nels - Mindsuck...
TWiEVO 32: Never not neutral
June 19, 2018 22:13 - 1 hour - 45.8 MBMatt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data. Hosts: Nels Elde and Vincent Racaniello Guest: Matt Hahn Become a patron of TWiEVO Hahn Lab Molecular Population Genetics by Matt Hahn Neutral theoryin light of natural selection (Mol Biol Evol) Neutral Sequence Fallacy(Assembly of Fragments) Splendor and miseryof adaptation (BMC Biol) Image credit Letters readon TWiEVO 32 Science Picks Nels - Inaugura...
TWiEVO 31: Virus archaeology, or when the human genome is the junk
May 19, 2018 22:18 - 1 hour - 47 MBNels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Ancient hepatitis B virus genomes(Nature) Even more ancient HBV genomes(bioRxiv) Image credit Letters readon TWiEVO 31 Science Picks Nels - Sampling whale breathwith drones (Preprint) Vincent - Verge Science Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and...
TWiEVO 30: Driving Miss Maize-y
April 21, 2018 12:14 - 1 hour - 43.5 MBNels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the Cellmeeting Selfishcorn chromosomes (Cell) Dawe Lab- neocentromeres and meiotic drive Image credit Letters readon TWiEVO 30 Science Picks Nels - Craypot stinkhorn mushroom (Colus pusilus) Vincent -Doubts raised over plan to release h...
TWiEVO 29: Evolution on the wing
March 21, 2018 16:03 - 1 hour - 59.1 MBNels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the Cell meeting Mosquito evolution from blood feeding to nonbiting (PNAS) Mosquito blood feeding is not a free lunch (virology blog) Incomplete immunity and evolution of virulence (Science) Image credit Letters rea...
TWiEVO 28: Genetics of skin pigmentation in Africa
February 28, 2018 03:15 - 1 hour - 46 MBSarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans. Hosts: Nels Elde and Vincent Racaniello Guest: Sarah Tishkoff Become a patron of TWiEVO Molecular Evolution and the Cell meeting Sarah AMA on Reddit Genetics of African skin pigmentation (Science) Image credit Science Picks Nels - In Defense of Plants (Shrew Loo) Vincent - Contribution of NIH funding to new drug approvals Music on TWiEVO is perf...
TWiEVO 27: Coldevo
January 13, 2018 15:32 - 1 hour - 45.4 MBTaking a cue from the recent frigid weather, Nels and Vincent explore how modifications of a neuronal cold-sensing channel regulate diminished cold sensitivity in hibernating mammals. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Why ground squirrels and hamsters don't mind the cold (Cell Rep) Image credit Letters read on TWiEVO 27 Science Picks Nels - Undergrad podcasters from Stonehill College Vincent - Viruses at Target Music on TWiEVO is performed by Tr...
TWiEVO 26: My Scientist Vinny
December 07, 2017 15:23 - 1 hour - 42.6 MBVinny Lynch joins Nels and Vincent to discuss how a zombie gene in elephants protects these large, long lived animals from cancer. Hosts: Nels Elde and Vincent Racaniello Guest: Vinny Lynch Become a patron of TWiEVO Lynch Lab Elephant zombie LIF gene induces apoptosis (bioRxiv) Image credit Science Picks Nels - Animalism Vincent - Voyager I fires up thrusters after 37 years Vinny - Rollin' Wild Music on TWiEVO is performed by Trampled by Turtles Send your evolution qu...
TWiEVO 25: Pigeons show the way
November 22, 2017 23:31 - 1 hour - 57.4 MBNels and Vincent discuss a genomic analysis of the passenger pigeon, which shows that species with large and stable populations may be at risk of extinction after a sudden environmental change. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Passenger pigeon genomic diversity (Science) Image credit Letters read on TWiEVO 25 Science Picks Nels - Video of nematophagous fungi Vincent - How should novelty be valued in science? John - Evo-Devo (Despacito Biology Pa...
TWiEVO 24: Good viruses visiting bad neighborhoods
October 26, 2017 17:14 - 1 hour - 54.2 MBMarco Vignuzzi joins Nels and Vincent to discuss recent work from his laboratory on redirecting RNA virus evolution in sequence space. Hosts: Nels Elde and Vincent Racaniello Guest: Marco Vignuzzi Become a patron of TWiEVO Vignuzzi Laboratory Redirecting evolution of RNA viruses in sequence space (Nat Micro) Is quasispecies concept relevant to RNA viruses? (J Virol) This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in ...
TWiEVO 23: The Alus are going to be alright
September 20, 2017 20:25 - 1 hour - 43.2 MBNels and Vincent reveal how the protein DHX9 suppresses RNA processing defects caused by invasion of the Alu retroelement into the human genome. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO DHX9 suppresses Alu defects (Nature) Asifa Akhtar on The Latest Thinking This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your f...
TWiEVO 22: E pluribus cerevisiae
August 30, 2017 21:37 - 1 hour - 47.1 MBMaitreya Dunham joins Nels and Vincent to explain how her laboratory uses experimental evolution to study yeast flocculation, the community-building cell aggregation trait. Hosts: Nels Elde and Vincent Racaniello Guest: Maitreya Dunham Become a patron of TWiEVO Dunham Laboratory Adaptive Routes to Cell Aggregation in Yeast (Genetics) Making the best of a sticky situation (SGD) Yeast Genetics and Genomic Course (Cold Spring Harbor) Genetic basis of biofilm formation (Beacon) ...
TWiEVO 21: A virus with a green thumb
July 13, 2017 01:35 - 1 hour - 60.8 MBRich Condit joins Nels and Vincent to explain how a vaccinia virus protein customizes ribosomes to favor the translation of viral mRNAs with a stretch of A residues in the 5'-untranslated region. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Rich Condit with Harry Noller (scroll down) Trans-Kingdom mimicry? (Nature) More on RACK1 (Nat Struct Mol Biol) Image credit Letters read on TWiEVO 21 This episode is brought to you by Blue Apron. Blue Apron is the #...
TWiEVO 20: In the company of cnidarians
June 20, 2017 00:34 - 1 hour - 59.2 MBNels and Vincent explore the role of TSR proteins during colonization of cnidarians by dinoflagellates. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO TSR domain proteins in cnidarian-dinoflagellate symbiosis A. elegantissima image credit Letters read on TWiEVO 20 Science Picks Nels - CRISPR 5 ways Vincent - The Vital Question by Nick Lane Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to [email protected]
TWiEVO 19: The beauty of the story
May 24, 2017 13:18 - 1 hour - 48.6 MBJonathan Weiner, author of the Pulitzer Prize-winning Beak of the Finch, joins Nels and Vincent to talk about his career and his writing. Hosts: Nels Elde and Vincent Racaniello Guest: Jonathan Weiner Become a patron of TWiEVO Jonathan's Columbia University page Jonathan's author page Science Picks Nels - The Gap by Ira Glass Vincent - EPA removes climate science site Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@mi...
TWiEVO 18: Raiders of the lost orco
April 10, 2017 18:00 - 1 hour - 64.1 MBHosts: Nels Elde and Vincent Racaniello Guests: Ni-Chen 'Sylvia' Chang, Waring 'Buck' Trible, and Sean K. McKenzie Buck and Sean join Vincent in New York, while Sylvia is with Nels in Salt Lake City to discuss the first mutant ant ever made: disruption of orco, a gene required for function of odorant receptors, show defects in social behavior and fitness. Become a patron of TWiEVO First ant mutants link odorant receptors and social behavior (bioRxiv) Kronauer Lab This episode i...
TWiEVO 17: The curious cases of clam cancers
March 13, 2017 17:58 - 1 hour - 44.3 MBHosts: Nels Elde and Vincent Racaniello Guest: Stephen Goff Nels joins Vincent in New York City to speak with Stephen Goff about transmissible clam cancers and the silencing of integrated retroviral genomes. Become a patron of TWiEVO A sixth modality of infectious disease (PLoS Path) Horizontal transmission of clam cancer (Cell) Transmissible bivalve cancers (Nature) Retrovirus transcriptional silencing (J Virol) Histones on retroviral DNA (Cell Host Micr) Image credit This...
TWiEVO 16: Breaking in the making of genes
February 25, 2017 13:40 - 1 hour - 44.7 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent reveal how introns - the parts of pre-mRNAs that are removed by splicing - were generated by DNA transposons in two different picoeukaryotes. Become a patron of TWiEVO Introns from DNA transposons (Nature) Reverse transcription and integration lecture Image: Elde Lab Mobile Studios on location in Santa Fe, NM Letters read on TWiEVO 16 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient an...
TWiEVO 15: From cockroaches to grizzly bears
January 22, 2017 19:07 - 1 hour - 61 MBHosts: Nels Elde and Vincent Racaniello Guest: Hopi Hoekstra Nels and Vincent speak with Hopi Hoekstra about her career and the work of her laboratory on developmental mechanisms of stripe patterns in rodents. Become a patron of TWiEVO Hoekstra Laboratory Hopi on Twitter Mechanisms of stripe patterns in rodents (Nature) Image credit Letters read on TWiEVO 15 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the...
TWiEVO 14: TWi-light on the Wasatch Front
December 22, 2016 02:56 - 1 hour - 63.1 MBHosts: Nels Elde and Vincent Racaniello Guests: Jessica Brown, Michael Kay, Wayne Potts, June Round, and Janis Weis From the Microbial Pathogenesis Retreat of the University of Utah School of Medicine, held at the Utah Museum of Natural History, Nels and Vincent speak with faculty members about their work on bacteria, fungi, viruses, and mirror-image biochemistry. Watch video of this episode at YouTube Become a patron of TWiEVO This episode is sponsored by CuriosityStream, a su...
TWiEVO 13: This week in ants
November 16, 2016 02:22 - 1 hour - 53.2 MBHosts: Nels Elde and Vincent Racaniello Guest: Corrie Moreau Corrie joins Nels and Vincent to talk about her comparative analysis of the genomes of mutualist ants that nest in plants, and non-symbiotic species. Become a patron of TWiEVO Links for this episode Moreau Laboratory Different rates of evolution in ant-plant mutualisms (Nat Commun) Image credit This episode is sponsored by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and n...
TWiEVO 12: Take a left at the goats
October 19, 2016 11:30 - 1 hour - 66.7 MBHosts: Nels Elde and Vincent Racaniello Guest: Josh Drew Josh joins Nels and Vincent to talk about his research on the evolution and conservation of aquatic tropical biodiversity, and the historical ecology of 19th century American Whalers. Become a patron of TWiEVO Links for this episode Drew Laboratory at Columbia University American Whalers by Ed Yong Karen Bao Sea cucumber genome Sea cucumber population connectivity (Nature) This episode is sponsored by CuriosityStream...
TWiEVO 11: Microbial accomplices in multicellularity
September 27, 2016 19:27 - 1 hour - 60.9 MBHosts: Nels Elde and Vincent Racaniello Guest: Nicole King Nicole joins Nels and Vincent to discuss the finding of her laboratory that multicellular development of choanoflagellates, the closest living relatives of animals, is regulated by bacterial lipids. Become a patron of TWiEVO Links for this episode Nicole King on Twitter Choanoflagellate workshop Bacterial lipids regulate Salpingoeca development (PNAS) Image credit Letters read on TWiEVO 11 This episode is sponso...
TWiEVO 10: Spicing up peppered moths with a selfish gene
August 13, 2016 14:17 - 1 hour - 66.5 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent review experiments showing that the replacement of a pale moth with a black one during the industrial revolution was caused by a transposable element. Links for this episode Last experiment of Michael Majerus (Biol Lett) Moth melanism mutation is transposon (Nature) Image credit Letters read on TWiEVO 10 Science Picks Nels - Is Pokémon Go good for science? (one, two, three) Vincent - Seven Brief Lessons on Physics by...
TWiEVO 9: How to crash your gene drive
July 05, 2016 12:30 - 1 hour - 69.1 MBHosts: Nels Elde and Vincent Racaniello Guest: Jim Bull Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve. Links for this episode Lethal gene drive selects inbreeding (bioRxiv) Panel endorses gene drive technology (NY Times) Genes in Conflict by Austin Burt Letters read on TWiEVO 9 Science Picks Nels - Fertilization with...
TWiEVO 8: Everyone's a little bit Neanderthal
June 08, 2016 15:35 - 1 hour - 68.8 MBHosts: Nels Elde and Vincent Racaniello Nels visits Vincent in the MicrobeTV studio in New York and talks about how key genes of the Homo sapiens innate immune response were acquired from Neanderthals. Links for this episode Introgressed Neanderthal haplotype at OAS locus (biorXiv) Genetic time travel (Genetics) Genetic history of Ice Age Europe (Nature) Letters read on TWiEVO 8 Science Picks Nels - DNA Clues to our Inner Neanderthal Vincent - Blockhead Music on TWiEVO i...
TWiEVO 7: Pigeon fashion week, feathery boots edition
April 23, 2016 14:48 - 1 hour - 58.1 MBHosts: Nels Elde and Vincent Racaniello Guest: Mike Shapiro Mike joins Nels and Vincent to talk about his work on what controls whether pigeons have scaly or feathered feet, and reveals that the hindlimbs of domestic birds with feathery feet are more like wings at the molecular level. Links for this episode Shapiro Laboratory Shifts in limb identity underlie development of feathered feet (eLife) Photo of Muffed Fairy Swallow by Sydney Stringham Science Picks Mike - Pigeon exhibit...
TWiEVO 6: Butterflies are free to shuffle
March 19, 2016 02:16 - 1 hour - 71 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent continue with an emerging sub-theme of TWiEVO - organisms with wings - as they reveal how enhancer shuffling produces diverse butterfly wing patterns. Links for this episode Enhancer shuffling for butterfly wing patterns (PLoS Biol) Batesian mimicry (Wikipedia) Müllerian mimicry (Wikipedia) Image credit Letters read on TWiEVO 6 Science Picks Nels - Hill Country Science Mill Vincent - The Butterfly Conservatory Listener Pic...
TWiEVO 5: Looking at straw colored fruit bats through a straw
February 20, 2016 20:22 - 1 hour - 69.1 MBHosts: Nels Elde and Vincent Racaniello Guests: Kartik Chandran and Sara Sawyer Sara and Kartik join Nels and Vincent to talk about the filovirus receptor NPC1 regulates Ebolavirus susceptibility in bats. Links for this episode Sara on TWiV #193 Kartik on TWiV #314 NPC1 and bat susceptibility to Ebolaviruses (eLife) Science Picks Nels - Sundance Film Festival and Meru Vincent - Quanta podcast (iTunes) Sara - Isolation of Marburg viruses from fruit bats Music on TWiEVO is performe...
TWiEVO 4: Taking the mystery out of the mystery of mysteries
January 23, 2016 15:29 - 1 hour - 67.1 MBHosts: Nels Elde and Vincent Racaniello Guest: Nitin Phadnis Nitin joins Nels and Vincent to explain how he identified a gene that is responsible for male inviability in hybrids from a cross between two species of fruit flies. Links for this episode Cell cycle regulation gene causes hybrid inviability in fruit fly (Science) Phadnis laboratory Phadnis laboratory on Facebook Gene for new species discovered (UNews) Tardigrade HGT disputed (bioRxiv) Photo credit: Lee J. Siegel, ...
TWiEVO 3: Recombination is for the birds
January 09, 2016 16:14 - 1 hour - 58.1 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent discuss the evolution of recombination in the genomes of birds and yeast. Links for this episode Stable recombination hotspots in birds (Science) Putting the breaks on meiosis (Science) Evolutionary stability of recombination in yeast (Science) Image credit Science Picks Nels - Tardigrade horizontal gene transfer (The Atlantic article) Vincent - Einstein's theory of relativity changed everything Music on TWiEVO is perfo...
TWiEVO 2: Faster than a speeding virus
December 26, 2015 16:54 - 1 hour - 51 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent talk about how a cellular enzyme contributes to the very high mutation rate of human immunodeficiency virus type 1. Links for this episode Cell defense enzyme drives high HIV mutation rate (PLoS Biol) High mutation rate of HIV in vivo (PLoS Biol) High viral mutation rates are beneficial (virology blog) Image credit Science Picks Nels - Antelope Island State Park (Bison herders wanted) Vincent - Processed meats cause cance...
TWiEVO 1: When (scientific) worlds collide
December 12, 2015 14:30 - 1 hour - 52.3 MBHosts: Nels Elde and Vincent Racaniello Nels and Vincent launch a new podcast on evolution, and start by discussing how the field has changed through recent mergers of evolutionary and experimental biology in the post-genome era. Links for this episode Elde Laboratory Nels on TWiV 234 Mechanistic approaches to the study of evolution (Nat Rev Gen) Australian sheep blowfly (Wikipedia) Hopi Hoekstra Science Picks Nels - Your inner fish (video stream, Shubin website) Vincent - Pr...