Dr. Asaf Hellman: Methylation of DNA, Relationship to Disease
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English - June 18, 2022 05:00 - 44 minutes - 40.6 MB - ★★★★★ - 239 ratingsNatural Sciences Science Education biotech science life science plant biology agriculture agtech biology Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
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Epigenetic regulation of gene expression occurs via many mechanisms. One method is the methylation of regulatory sequences that control the expression of specific genes. Methylation is the addition of a small methyl group to specific bases of the DNA helix. Addition of a methyl group can change how the DNA blueprint is accessed and expressed. Today's guest is Prof. Asaf Hellman. His group has found relationships between the methylation state of DNA and expression of genes associated with diabetes and cancers. Understanding these patterns may help inform predisposition to disease, as well as eventually causal factors and drug targets.