PubReading [304] - What are Biomarkers? - K. Strimbu and J. Tavel
PubReading
English - March 10, 2023 12:00 - 23 minutes - 21.7 MBLife Sciences Science Health & Fitness Medicine Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
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This article provides working definitions and a conceptual framework to understand the roles of biomarkers in clinical research. The definitions of the terms discussed in this article—medical signs, symptoms, biomarkers, surrogate endpoints, clinical endpoints, validation—are still under discussion, as are their relationships to each other, but broad consensus has developed in the past decade and a half about the necessity of distinguishing between, in particular, surrogate and clinical endpoints.
doi:10.1097/COH.0b013e32833ed177. - 2010