PubReading [303] - The Epigenomics of Cancer - P. Jones and S. Baylin
PubReading
English - March 09, 2023 12:00 - 41 minutes - 37.8 MBLife Sciences Science Health & Fitness Medicine Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Aberrant gene function and altered patterns of gene expression are key features of cancer. Growing evidence shows that acquired epigenetic abnormalities participate with genetic alterations to cause this dysregulation. Here, we review recent advances in understanding how epigenetic alterations participate in the earliest stages of neoplasia, including stem/ precursor cell contributions, and discuss the growing implications of these advances for strategies to control cancer.
DOI 10.1016/j.cell.2007.01.029 -2007