Acute Kidney Injury with Dr. Archana Dhar and Dr. Molly McGetrick--Part 3

Acute Kidney Injury (AKI) with Dr. Archana Dhar and Dr. Molly McGetrick 

About our guests:

Dr. Dhar is a is an associate Professor of Pediatrics and practicing pediatric intensivist at Children’s Medical Center and UT Southwestern in Dallas.

Dr. McGetrick recently completed her pediatric critical care fellowship training at UT Southwestern and is a current pediatric cardiovascular ICU fellow at Texas Children’s. 

Learning Objectives: 
After listening to this series of episodes, learners should be able to:

Define AKI.Discuss incident and epidemiology of AKI in the pediatric critical care setting.Know how to diagnose AKI according to the KDIGO guidelines.Recall the role of biomarkers and renal angina index in risk stratification and early identification of AKI.Discuss a clinical approach to managing a patient with acute kidney injury.

Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at [email protected]. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates

Thanks again for listening! 

References/Further Reading: 

Sethi SK, Bunchman T, Chakraborty R, Raina R. Pediatric acute kidney injury: new advances in the last decade. Kidney Res Clin Pract. 2021 Mar;40(1):40-51. doi: 10.23876/j.krcp.20.074. Epub 2021 Mar 3. PMID: 33663033; PMCID: PMC8041642.

Alobaidi R, Anton N, Burkholder S, Garros D, Garcia Guerra G, Ulrich EH, Bagshaw SM. Association Between Acute Kidney Injury Duration and Outcomes in Critically Ill Children. Pediatr Crit Care Med. 2021 Feb 26. doi: 10.1097/PCC.0000000000002679. Epub ahead of print. PMID: 33729733.

Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL; AWARE Investigators. Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults. N Engl J Med. 2017;376(1):11-20. doi:10.1056/NEJMoa1611391 

Hessey E, Melhem N, Alobaidi R, Ulrich E, Morgan C, Bagshaw SM, Sinha MD. Acute Kidney Injury in Critically Ill Children Is Not all Acute: Lessons Over the Last 5 Years. Front Pediatr. 2021 Mar 15;9:648587. doi: 10.3389/fped.2021.648587. PMID: 33791260; PMCID: PMC8005629.

Basu RK, Kaddourah A, Terrell T, et al. Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study. BMC Nephrol. 2015;16:24.

Schneider J, Khemani R, Grushkin C, Bart R. Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med. 2010;38:933–9. doi: 10.1097/CCM.0b013e3181cd12e1.

Villarreal EG, Rausa J, Chapel AC, Loomba RS, Flores S. Effects of Fenoldopam in the Pediatric Population: Fluid Status, Serum Biomarkers, and Hemodynamics: A Systematic Review and Meta-Analysis. J Pediatr Intensive Care. 2021 Jun;10(2):118-125. doi: 10.1055/s-0040-1714704. Epub 2020 Aug 10. PMID: 33884212; PMCID: PMC8052110.