In this episode of the "Over 40 Fitness Hacks" podcast, host Brad Williams interviews Dr. Carl Giordano, an aging expert, to discuss the latest research and experiments on longevity. Dr. Carl provides insights on supplements and lifestyle changes that can help individuals reach the century mark and beyond. He emphasizes the importance of vitamin D and B12 for bone health, immune function, and brain health, while also discussing the role of omega-3 fatty acids and the potential risks of an excessive omega-6 intake.

The conversation then shifts to the concept of signal molecules, which stimulate specific genetic pathways related to healthspan and lifespan. Dr. Carl highlights five key signal molecules: NMN (nicotinamide mononucleotide), berberine, resveratrol, glutathione, and quercetin. He explains how each of these molecules works on different longevity gene pathways and exhibits powerful antioxidant and anti-inflammatory properties. Dr. Carl shares his personal experience with these molecules and their impact on biological age.

To simplify the intake of these molecules, Dr. Carl introduces Revana, a supplement that combines all five signal molecules in convenient doses. He emphasizes the need to take them with food or a fatty substance to ensure proper absorption. Brad and Dr. Carl also discuss the importance of timing and personalizing supplement intake, particularly for individuals following intermittent fasting protocols.

Listeners are encouraged to explore these supplements and consider their potential benefits for improving health and slowing down the aging process. Dr. Carl concludes the episode by reiterating the belief that aging is malleable and that by optimizing cellular pathways, individuals can decelerate the aging process and promote better overall well-being.

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