OncoAlert

The Hematology Round Up at #ASCO24

Dear Colleagues, Welcome to this Hematology Round Up from  hashtag #ASCO24 . WE have focused on Hematologic malignancies with 3 presentations which were presented on June 2nd, 2024 The first presentation was the Phase 3 study results of isatuximab, bortezomib, lenalidomide, and dexamethasone (Isa-VRd) versus VRd for transplant-ineligible patients with newly diagnosed multiple myeloma (IMROZ) . Presented by Dr. Facon This trial presentation came with a concomitant publication on the New En...

The OncoAlert🚨Weekly Newsletter May 3-9, 2024

✅ TheLancet Commission on #ProstateCancer  ✅DESTINY-PanTumor01 ✅Osimertinib+Local tx for brain🧠mets in EGFRm #NSCLC 🫁 ✅ASCENT in Triple Negative #BreastCancer 🧪 ✅Bilateral Oophorectomy  in BRCA1&2🧬 ✅Racialized inequities in live birth after cancer🤰🏾 ✅MITO END in Endometrial Cancer ✅Tx Patterns Advanced Urothelial Carcinoma🇺🇸 and more‼️

The OncoAlert Weekly Round Up 🚨Covering April 26- May 1st, 2024

The OncoAlert Weekly Round Up 🚨Covering April 26- May 1st, 2024 REGISTER at http://OncoAlert360.com OR https://oncoalert.m-pages.com/nhMpwe/oncoalert-newsletter-registration COVERING DESTINY-Breast06 Monarch E US Preventive S Task force #BreastCancer Screen @US_FDA approval of Tisotumab vedotin NEO predict-Lung Pushing Boundaries in ctDNA StereotactiveRT in oligomet #KidneyCancer Thromboembolic Risk in #ProstateCancer Patients Treated with PARP Inhibitors @CancerCareMASCC -  @ASCO Sta...

The GU Cast, Uromigos, OncoAlert Reunion

What happens when Five Friends initially brought together by oncology meet up in Lugano for #APCCC24..........Magic...thats what! Join Renu, Declan, Brian, Tom and Gil on this insanely casual and fun conversation on the side 

The OncoAlert Weekly Round Up 🚨Covering April 19-25, 2024

The OncoAlert  Weekly Round Up Covering April 19-25, 2024 REGISTER AT http://OncoAlert360.com OR https://oncoalert.m-pages.com/nhMpwe/oncoalert-newsletter-registration Discussing ADCs in #LungCancer & #BreastCancer  Out on  @Annals_Oncology https://annalsofoncology.org/article/S0923-7534(24)00108-X/abstract TILS in #TNBC https://jamanetwork.com/journals/jama/article-abstract/2816923 TROPION in #BreastCancer https://ascopubs.org/doi/full/10.1200/JCO.23.01909 DE-REAL in #BreastCancer h...

The OncoAlert🚨ROUND UP Covering April 12-18, 2024

✅Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma out on @NEJM  https://www.nejm.org/doi/full/10.1056/NEJMoa2312695#ap0 ✅Timing of Radiotherapy (RT) After Radical Prostatectomy (RP): Long-term outcomes in the RADICALS-RT trial  https://www.annalsofoncology.org/article/S0923-7534(24)00105-4/fulltext ✅Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum https://www.cell.com/cell-...

The OncoAlert Round Up April 5th-12th, 2024

The  @OncoAlert RoundUp is Out Covering April 5th-12th, 2024 REGISTER at http://OncoAlert360.com OR https://oncoalert.m-pages.com/nhMpwe/oncoalert-newsletter-registration Discussing:   @US_FDA   approval trastuzumab dx Durvalumab in Small Cell #LungCancer ALINA  #NSCLC out on  @NEJM   CD70 CART in #KidneyCancer Adagrasib Cetux in #colorectalcancer  and more

The OncoAlert Round Up March 28- April 4, 2024

The Top News, publications and trials in Oncology for the week of March 28- April 4, 2024 SENOMAC out in NEJM on Breast Cancer ACS & IARC 2022 Cancer Statistics and more

The OncoAlert Podcast: TOP TRIALS IN GU Oncology Feb 23-29, 2024

JAVELIN Renal 101 Out on Cancer Discovery FASTRACK II Out on Lancet Oncology ONE SHOT (in Prostate cancer) Out on the Green Journal

The OncoAlert Round Up ASCO GU 2024 (Day One/ Prostate Cancer)

Contact 02 Embark/ GETUG 18 FORMULA 509 BRCA Away

The OncoAlert Round Up Jan 11-18, 2024 (week in Oncology)

Discussing: Updated Cancer statistics from American Cancer SocietyNORPACT 1 in #PancreaticCancer   FDA approval in Cervical Cancer Immune onc advances in GU Onc from the ASCO Ed bookLow dose SOC Olanzapine in Nausea Genomic Landscape of acquired resistance to PDL1 in #NSCLC and More

The OncoAlert Round Up Jan 5-11, 2024

Discussing:    @ASCO @SocSurgOnc Germline Testing @ASTRO_org Partial Breast Irradiation in early Invasive Breast Cancer or DCIS ERMES in #ColorectalCancer Vision in #ProstateCancer AMPLIFY 201 #Cance #vaccine in CRC NACI study in #CervicalCancer FUTURE-SUPER trial in #TNBC Adj Abemaciclib+ET in HR+HER- HighRisk 

The OncoAlert Round Up Sept 22-28, 2023

Discussing: KeyNote A39 in #BladderCancer CheckMate 77Tin #LungCancer Tropion Breast01 in #BreastCancer Pooled CtDNA analysis of MONALEESA Modulation Microbiota toenhance #Immunotherapy  and more.....

The OncoAlert round Up September 15-21, 2023

The @OncoAlert Newsletter  September 21, 2023 Register at http://OncoAlert360.com Discussing: VP-2023 HRQoL in NATALEE #BreastCancer Oligomets in #ProstateCancer  treated w SBRT EV301: Enfortumab VendotinChemo in Urothelial Ca Targeting Innate immune pathways in Cancer #Immunotherapy Osimertinib early dose reduction as risk to brain mets in EGFR mutant #NSCLC #LungCancer

The OncoAlert BEST of World Conference on Lung Cancer 2023

SPECIAL  LUNG CANCER PODCAST #WCLC23 World Conference #LungCancer TO GET IT REGISTER AT: http://OncoAlert360.com FLAURA MARS TMN Staging DESTINY LUNG Herthena TRIDENT EVOKE ISABR RIOT and more A great way to catch up on all the great Science presented in Singapore

The @oncoAlert Round Up September 1- 7, 2023

The  @oncoAlert  Round Up September 1- 7, 2023 REGISTER TO GET IT at  http://OncoAlert360.com  Discussing:  @fda Breakthrough therapy designations for Trastuzumab deruxtecan Sequencing Endocrine & Targeted Txin Hormone sensitive HER2- #breastcancer Neoadj palbociclib+giredestrant or anastrozole in ER+, HER2- early breast #cancer Exercise& Nutritionon Chemo Completion & pCR in Breast #Cancer Bladder-Sparing Treatment w/ Radical Dose RT Is Effective Alternative to Radical Cystectomy in Node...

The OncoAlert Round Up August 25-31, 2023

Discussing: EMAapproval of Pembro+Trastuzumab+Chemo in Gastric Cancer based on KeyNote 811 LUNARin metastatic #NSCLC ASTRRAin #BreastCancer Cannabinioidsin children with #Cancer IO in treatment of Localised GU Cancers LMWH synergistically enhances efficacy of adoptive and anti-PD-1-based #Immunotherapy  .....and more Register at www.oncoalert360.com

The OncoAlert Round Up August 17-24, 2023

LITESPARK005 in #KidneyCancer TBCRC 030 in TN #BreastCancer CONTACT02in #prostatecancer MRIto help diagnose #ProstateCancer LIBRETTO 531in #ThyroidCancer SBRT in HCC #LiverCancer

The OncoAlert Round Up August 4-10, 2023

REGISTERto get it www.OncoAlert360.com Discussing: @US_FDA approval of LONSURF+Bev in CRC selpercatinib in RET+ #NSCLC erdafitinib in Tumor Agnostic setting: RAGNAR Cause Specific Mortalityof Race & Ethnicity Stereotactic Body Reirradiationin Gyn Cancer Depression, anxiety & #Cancer Risk and more

The OncoAlert Round Up July 28 to August 3, 2023

The Top news in Oncology of the week covering July 28 to August 3, 2023

Day Four Round Up ASCO 2023 (THOR, CONTACT03, CLEAR, SONIA)

Day 2 Round Up ASCO 2023 (Keynote 826, Keynote 671, DUO-O)

DAY ONE ROUND UP OF ASCO 2023 (NATALEE, MonarchE)

DAY 3 Round Up ASCO 2023 (ADAURA, PROSPECT, TALAPRO2 and INDIGO

Day 3 Wrap Up of AACR 2023 by OncoAlert (Aegean, KeyNote942, IMBRAVE050)

OncoAlert Podcast AACR23 Day 2 Wrap Up (MoonShot, ROAR, SAMBA101)

Day One of AACR23 and Papers of the week April 15, 2023

The #OncoAlert Tumor Boards in Prostate Cancer

Case Discussion Localised High Risk #ProstateCancer 58yr old male DRE: Hard mass c3 PSA 12.4 Gleasons 4+5=9 Imaging M0 later PSMA M1 in bone Faculty  Dr. Neeraj Agarwal Dr. Eleni Efstathiou Dr. Axel Merseburger Dr. Sean McBride

ASCO22 OncoAlert Round up DAY1

Dear Colleagues, Welcome to the ASCO22 RoundUp for Day one of the congress Starting with with KRYstal1 with a concomitant publication in the New England Phase One report of Adagrasib in Non Small Cell Lung Cancer, targeting KRAS G12C shows promise in  clinical efficacy without new safety signals Large number of response  median follow-up of 12.5 months the median PFS 6.5 months   median OS 12.6 months The EVEREST Trial Adjuvant everolimus improves RFS in resected renal cell carcinom...

The OncoAlert Tumor Boards in Breast Cancer May 12, 2022

41 year female, no past medical history Comes to MedOnc after left breast lumpectomy & SN evaluation Path: 2.1 cm grade 2 tumor ER 100% PR 90% Her2 1+ FISH- 1/2 Sentinel Node positive (4mm tumor deposit w/extranodal extension) Systemic staging- OncotypeDX 20 #BreastCancer #OncoAlertTB Dr. Hamilton Dr. Lustberg Ms. Mapes Dr. Lambertini Dr. Meattini  Moderators Dr. Grainne O'kane Dr. Ben Westphalen Host Dr. Gil Morgan

The OncoAlert Tumor Boards in Non Small Cell Lung Cancer April 13, 2022

The case 42 year old female never smoker Comes to the ER with sudden onset chest pain Radiology finds 4.2cm left-sided lung mass & enlarged mediastinal LN on staging PET/CT and Brain MRI. Staged as cT2bN2 (Stage IIIA) #NSCLC Surgically resectable #lungcancer #LCSM #OncoAlertTB  Experts Dr. Narushka Naidoo Dr. Jack West Dr. Brendon Stiles Dr. Henning Willers Dr. Christian Rolfo Moderators Dr. Grainne O'kane Dr. Ben Westphalen Host Dr. Gil Morgan

The OncoAlert Podcast Recap for the ASCO Plenary Series: CODEBREAK

First data from CODEBREAK Sotorasib in G12C mutant Pancreatic Cancer  Presented Feb 15, 2022 by Dr. John Strickler of Duke Medical Center

3 FDA approvals following MonarchE, Impower010 & KEYNOTE826 (Drs. Hamilton, Dizon & Liu)

DESTINY Breast 03 OncoByte with Dr. Javier Cortes of Vall d'Hebron institute

Our OncoAlert Colleague & Breast Cancer faculty Dr. Javier Cortes gives us a break down of DESTINY Breast 03 presented at the presidential symposium as Late Breaking Abstract 1 Trastuzumab Deruxtecan vs Trastuzumab Emtansine in patients with HER2+ metastatic breast cancer. Results of the Phase 3 DESTINY BREAST 03 trial

Tweetorial on KeyNote564 by Dr Toni Choueiri just out on NEJM

NEW episode of the  OncoAlert PodCast featuring the Amazing DrChoueiri of @DanaFarber   A Tweetorial on KeyNote 564 & its latest publication out on  @NEJM  Adj Pembro after nephrectomy in Renal Cell Carcinoma Catch it this Monday August 23

The OncoAlert Podcast TROPHY U 01 & TITAN (GU Oncology)

TROPHY-u-01: A phase II open-label study of sacituzumab govitecan (IMMU-132) in patients with advanced urothelial cancer after progression on platinum-based chemotherapy and/or anti-PD-1/PD-L1 checkpoint inhibitor therapy. with Dr. Scott Agawa and Dr. Petros Grivas https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.7_suppl.TPS495 Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study with D...

The OncoAlert podcast COVID19 & Cancer

A great pleasure to talk to Dr. Vivek Subbiah, Dr. Petros Grivas and Dr. Ali Khaki regarding 2 great papers just out discussing COVID19 and Cancer COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials https://www.nature.com/articles/s41571-021-00487-z Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium https://www.annalsofoncology.org/articl...

The OncoAlert Podcast for ASCO #GU21

Dr Toni Choueiri of Dana Farber  The 4 oral presentations on metastatic Renal Cell Carcinoma Dr. Sumanta Pal of City of Hope Update on CheckMate274 Dr. Tian Zhang of Duke Cancer Center On the two studies presented at GU21 with Enfortumab Vedotin in advanced Urothelial Carcinoma Dr. Neeraj Agarwal The Huntsman Cancer Institute With updates on advanced prostate cancer including the Titan study

The OncoAlert Podcast: Interview with Dr. Fumiko Chino on Financial Toxicity of Cancer Care

As we wrap up our Oncoalert podcasts before the US election. We shift the focus to our patients and how financial toxicity plagues people with cancer.  Our OncoAlert Colleague Dr. Fumiko Chino, Radiation Oncologist at Memorial Sloan Kettering tells us more. 

The OncoAlert Podcast: Conversation with Dr. Henry Henderson Co-Founder of #BlackinCancer

With the US elections coming soon, the OncoAlert Network discusses hot topics in Science and medicine.  This week we have the pleasure of talking to Dr. Henry Henderson of Vanderbilt University and a mentee of Dr. Christine Lovly. Dr. Henderson is a co creator of the #BlackinCancer Movement highlighting talented and inspiring scientists through social media  and works towards getting more African Americans into science and medicine. Its all about representation!

The OncoAlert Podcast: Conversation with Dr. Narjust Duma

A casual Conversation with Dr. Narjust Duma of the University of Wisconsin on being hispanic doctors, feminists and a role model. 

The OncoAlert Podcast for October 11, 2020 (KATE2, COVID19 & EZH2 inh) Drs. Loi, Bakouny & Subbiah

Trastuzumab emtansine plus atezolizumab versus trastuzumab emtansine plus placebo in previously treated, HER2-positive advanced breast cancer https://www.sciencedirect.com/science/article/abs/pii/S1470204520304654 COVID-19 and Cancer:Current Challenges and Perspectives https://www.cell.com/cancer-cell/fulltext/S1535-6108(20)30492-X EZH2 inhibition for epithelioid sarcoma and follicular lymphoma https://t.co/HXkSxs9O5g?amp=1

The OncoAlert Podcast for October 4th, 2020 (PROFOUND, JAVELIN RENAL100, ESMO Fertility Guidelines) Drs. Agarwal, Grivas & Lambertini

The PROFOUND Prostate Cancer trial by Dr. Neeraj Agarwal https://www.nejm.org/doi/full/10.1056/NEJMoa2022485 The ESMO fertility Preservation Clinical Practice Guidelines by Dr. Matteo Lambertini https://www.annalsofoncology.org/article/S0923-7534(20)42448-2/fulltext The JAVELIN Bladder 100 Trial by Dr. Petros Grivas https://www.nejm.org/doi/full/10.1056/NEJMoa2002788

The OncoAlert Podcast for September 27, 2020 (CheckMate9ER, monarchE, ADAURA) with Drs. Choueiri, Hamilton & Liu

https://www.esmo.org/newsroom/press-office/esmo2020-metastatic-kidney-cancer-nivolumab-cabozantinib-checkmate9er .................. https://ascopubs.org/doi/full/10.1200/JCO.20.02514 ................. https://www.nejm.org/doi/full/10.1056/NEJMoa2027071

The OncoAlert Podcast for September 27, 2020 (KeyNote9ER, monarchE, ADAURA) with Drs. Choueiri, Hamilton & Liu

https://www.esmo.org/newsroom/press-office/esmo2020-metastatic-kidney-cancer-nivolumab-cabozantinib-checkmate9er .................. https://ascopubs.org/doi/full/10.1200/JCO.20.02514 ................. https://www.nejm.org/doi/full/10.1056/NEJMoa2027071

The OncoAlert Podcast for September 19, 2020 ( TIVO3 & KEYNOTE 158 with Drs. Pal, Subbiah & Patel)

Welcome to the OncoALert weekly podcast In this podcast we will be discussing two papers The first  “Final Overall Survival Results from a Phase 3 Study to Compare Tivozanib to Sorafenib as Third- or Fourth-line Therapy in Subjects with Metastatic Renal Cell Carcinoma” published at European Urology  by Dr. Sumanta Pal The Second paper Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis...

The OncoAlert Podcast for September 13 ,2020 (Drs. Subbiah, Choueiri & Lambertini)

Thank you for joining us. Here are the 3 top papers of the week for discussion with author commentaries... Precision Targeted Therapy with BLU-667 for RET-Driven Cancers by Vivek Subbiah... https://cancerdiscovery.aacrjournals.org/content/8/7/836. ... Biomarker analysis of the Phase 3 JAVELIN RENAL 101 trial by Toni Choueiri... https://www.nature.com/articles/s41591-020-1044-8.epdf?sharing_token=hCo0HqG6ax_82DLJZZQJzNRgN0jAjWel9jnR3ZoTv0NMzYK0r0tt_kVQk-sdyEPP4S-BbMUmhGyREjbzAtqLRBvc8vD3vV...

The OncoAlert Podcast for September 6, 2020

Welcome to the oncoalert podcast for September 6th, 2020 We start off the week with some great news FDA Approves pralsetinib for the Treatment of Adults With Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer.  This is a once-daily, oral precision therapy that selectively inhibits RET-altered cancers – FDA also granted Priority Review to pralsetinib for the treatment of  advanced or metastatic RET-mutant medullary thyroid cancer and RET fusion-positive thyroid cancer  Paper 1.  Fi...

Welcome to OncoAlert

HI And welcome to the oncoalert Podcast My name is Gil Morgan I am the director of oncoalert Originally from Texas but working in Medical oncology in Sweden  OncoAlert is a worldwide network of oncology professionals and patients advocates who have banded together on social media in order to fight cancer with knowledge and the dissemination of oncology information.  We are made up of Medical, Radiation & Surgical oncologists, oncology nurses, scientist and ofcoufse our amazing patient adv...