Editors in Conversation
124 episodes - English - Latest episode: about 2 months ago - ★★★★ - 10 ratingsEditors in Conversation is the official podcast of the American Society for Microbiology Journals. Editors in Conversation features discussions between ASM Journals Editors, researchers and clinicians working on the most cutting edge issues in the microbial sciences. Topics include laboratory diagnosis and clinical treatment of infectious diseases, antimicrobial resistance, epidemiology of infections, multidrug-resistant organisms, pharmacology of antimicrobial agents, susceptibility testing, and more.
The podcast is directed to microbiologists, infectious diseases clinicians, pharmacists and basic, clinical and translational researchers interested in the microbial sciences. A particular emphasis is on basic, epidemiological and pharmacological aspects of infectious diseases, including antimicrobial resistance and therapeutics.
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Episodes
Is Lophomonas a Pathogen?
February 23, 2024 21:48 - 34 minutes - 23.8 MBThe protozoan Lophomonas has been reported to be a pathogen of humans in a large number of case reports and case series. Most of these case reports describe infections of the respiratory tract. Editors in Conversation is joined by two experts to discuss this possible parasite. Some of the questions addressed include: What are the characteristics of the species in the genus Lophomonas? What are the laboratory and morphological data that suggest that Lophomonas species cause human infect...
Treatment of Multidrug-resistant Tuberculosis
February 09, 2024 22:55 - 40 minutes - 27.8 MBTuberculosis is one of the most deadly infectious diseases that still causes significant burden of disease, particularly in the developing world. The emergence of resistance to first line agents severely limits the therapeutic options and threaten the ability to control dissemination of this disease. Fortunately, new drugs and regimens are now emerging as important alternatives against these organisms. Today, we will discuss this topic with outstanding experts in the field. Welcome to the ...
New generation B-lactam/B-lactamase inhibitors: Taniborbactam
January 13, 2024 03:46 - 47 minutes - 32.9 MBA new generation of B-lactamase inhibitors is likely to reach the market in the upcoming year. These broad-spectrum inhibitors exhibit activity against the most feared class B metallo-B-lactamases maintaining the inhibition of other enzymes. Recently AAC has published three papers that describe the mechanistic bases of taniborbactam resistance among metallo-enzymes. This knowledge is crucial to understand the limitation of these compounds in clinical practice. Today, we will discuss this top...
Favorite Clinical Microbiology Papers of 2023 (JCM ed.)
December 23, 2023 00:32 - 1 hour - 44.9 MBWe managed to make it through 2023 without a major epidemic or pandemic, and as we get into the holiday spirit and look forward to the new year, some of us took a look back and picked out one of our favorite JCM paper published in 2023, which I will tell you, was no easy task as there were many of good ones to choose from! And personally, after looking through all the issues over the last year, it never ceases to amaze me the variety of topics that we publish on in JCM – including unique thi...
Antimicrobial Resistance in Neisseria Gonorrhoeae (JCM ed.)
December 05, 2023 08:18 - 28 minutes - 19.5 MBGonorrhea remains one of the more common sexually transmitted infections. In North America, the number of reported cases has generally risen for over ten years, with interruptions in the early days of the COVID-19 pandemic, followed by returns to rising rates of infection. Under the selective pressure of antimicrobial treatment, antimicrobial resistance has risen, which has led to limited options for treatment Today, we will be discussing antimicrobial resistance in N. gonorrhoeae, includ...
New Antifungals (AAC ed.)
November 10, 2023 22:15 - 45 minutes - 31.6 MBIn the last few years we have witnessed the rise of very resistant fungal species some of them likely influenced by environmental conditions and climate change. Fortunately, there has been a bit of an explosion in the development of new antifungals and the pipeline has been strengthened in the last decade. We will have the ability to have new molecules with distinct and novel mechanisms of action in the near future that may contribute to combat recalcitrant fungal infections. Topics discus...
A Novel Coccidioides Antibody LFA (JCM ed.)
October 20, 2023 23:51 - 44 minutes - 30.3 MBDespite the many advances in diagnostic testing for infectious diseases, detection of Coccidoides infections continues to rely on serologic assessment for anti-fungal antibodies, and what is perhaps more astonishing is that the serologic methods we use today, such as complement fixation and immunodiffusion, were first developed about a century ago. These assays are technically challenging to maintain and perform, and as a result few labs offer this testing, and even if performed on-site, tes...
Climate Change and Antimicrobial Resistance (AAC ed.)
October 07, 2023 07:05 - 29 minutes - 20.3 MBClimate change is possibly the major threat that planet earth is experiencing in this century with potential catastrophic consequences. As the planet warms, the change in weather patterns is affecting the microbial ecology in such a manner that humans are facing new health threats including emerging diseases and facing species of organisms that are more likely to survive these new climatic conditions and resist clinically useful antimicrobials. Topics discussed: The global threat of globa...
Emerging Antifungal-Resistant Dermatophytes (JCM ed.)
September 22, 2023 23:35 - 29 minutes - 20.3 MBFungi that are resistant to antifungal drugs have been very much in the news and even the subject of the hugely popular television program, The Last of Us. We talk with two experts in mycology and fungal susceptibility testing about the recent descriptions of terbinafine-resistant dermatophytes in the United States. Some of the questions we will address include: • What are the manifestations of infections caused by terbinafine-resistant dermatophytes? • What species, including novel sp...
Artificial Intelligence and Infectious Diseases
September 08, 2023 23:12 - 38 minutes - 26.8 MBArtificial intelligence (AI) has the potential to change the way we practice medicine and public health. The tools and AI approaches can substantially impact a broad range of fields from the manner we approach patient care to strategies to discover new antimicrobials, track pandemics and deploy public health measures. AAC recently published a commentary on the impact of AI in infectious diseases and we have a conversation with the lead author of the manuscript and a expert guest who is ap...
Artificial Intelligence and Infectious Diseases (AAC ed.)
September 08, 2023 23:12 - 38 minutes - 26.8 MBArtificial intelligence (AI) has the potential to change the way we practice medicine and public health. The tools and AI approaches can substantially impact a broad range of fields from the manner we approach patient care to strategies to discover new antimicrobials, track pandemics and deploy public health measures. AAC recently published a commentary on the impact of AI in infectious diseases and we have a conversation with the lead author of the manuscript and a expert guest who is ap...
Viral Outbreaks in the Headlines (JCM ed.)
August 18, 2023 23:46 - 26 minutes - 18.6 MBDr. Elli Theel and Dr. Alex McAdam discuss recent viral outbreaks with expert virologists. Recorded before a live audience at ASM Microbe 2023. Topics: What are the recent epidemiologic and diagnostic findings with Mpox? What are the reservoirs for influenza A H5N1 and how is it transmitted to humans? Why was there such a large number of cases of human metapneumovirus this past respiratory virus season? Guests: Dr. Ben Pinsky, Director of the Clinical Virology laboratory and Profes...
AAC Launches a New Section Focused On Antimicrobial Stewardship
August 04, 2023 20:22 - 37 minutes - 25.7 MBIn response to the global burden of antimicrobial resistance (AMR) and the critical role antimicrobial stewardship plays in optimizing antibiotic use and reducing the subsequent emergence of AMR, Antimicrobial Agents and Chemotherapy is excited to add a new section to the journal focused on antimicrobial stewardship studies. Combatting the devastating burden of AMR requires novel, multipronged approaches from clinicians and scientists alike. Launching this new section is an important step in...
AAC Launches a New Section Focused On Antimicrobial Stewardship (AAC ed.)
August 04, 2023 20:22 - 37 minutes - 25.7 MBIn response to the global burden of antimicrobial resistance (AMR) and the critical role antimicrobial stewardship plays in optimizing antibiotic use and reducing the subsequent emergence of AMR, Antimicrobial Agents and Chemotherapy is excited to add a new section to the journal focused on antimicrobial stewardship studies. Combatting the devastating burden of AMR requires novel, multipronged approaches from clinicians and scientists alike. Launching this new section is an important step in...
Susceptibility Testing for Aztreonam with Ceftazidime-Avibactam (JCM ed.)
July 13, 2023 20:30 - 38 minutes - 26.8 MBThe combination of aztreonam with ceftazidime-avibactam is increasingly used for treatment of antimicrobial-resistant Gram-negative bacilli. Clinical laboratories are asked to perform susceptibility testing using this combination, but many laboratory directors have been unsure how to approach this. Today, we’ll discuss a recent paper in the Journal of Clinical Microbiology in which the investigators evaluated a promising method for testing this combination of two antimicrobials and a beta-la...
Susceptibility Testing for Aztreonam with Ceftazidime-Avibactam
July 13, 2023 20:30 - 38 minutes - 26.8 MBThe combination of aztreonam with ceftazidime-avibactam is increasingly used for treatment of antimicrobial-resistant Gram-negative bacilli. Clinical laboratories are asked to perform susceptibility testing using this combination, but many laboratory directors have been unsure how to approach this. Today, we’ll discuss a recent paper in the Journal of Clinical Microbiology in which the investigators evaluated a promising method for testing this combination of two antimicrobials and a beta-la...
Hispanic Leadership in Vaccine Sciences With Dr. Maria Elena Bottazzi (AAC ed.)
June 30, 2023 20:49 - 28 minutes - 19.8 MBRecorded at ASM Microbe 2023, Cesar has a conversation with Dr. Maria Elena Bottazzi about the role of minority women in science and discovery, the journey of Hispanic women in science and the current challenges posed by society to deliver science and global health equity. Guest: Dr. Maria Elena Bottazzi - Sr. Associate Dean of the National School of Tropical Medicine at Baylor College of Medicine, Distinguished Professor of Biology at Baylor University, Waco This episode is brought to ...
Updates on Testing for Vaginitis/Vaginosis (JCM ed.)
June 03, 2023 00:13 - 40 minutes - 28 MBAs many of you are likely aware, May is recognized as Women’s Health Care Month by the National Cervical Cancer Coalition, and this year, the CDC has identified the week of May 14th as National Women’s Health Week. So, what better way to recognize these national events on the podcast than to talk about diagnostics for a number of extremely common and uniquely female issues – of course, I’m talking about infectious causes of vaginitis and vaginosis. Classically, diagnosis of these infections ...
Management of Difficult to Treat HSV and CMV Infections (AAC ed.)
May 01, 2023 19:15 - 45 minutes - 31.5 MBAs the number of immunocompromised patients rise in our hospitals, the presentation of severe infections caused by HSV and CMV are rising. Most importantly, lack of response and documented resistance are becoming more frequently observed. Topics discussed: The clinical problems caused by resistant HSV and CMV infections. Mechanisms of resistance in these organisms. Insights into novel therapeutic approaches to treat resistant gonococcal infections. Guests: Christine M. Johnston, MD,...
Susceptibility Testing for Piperacillin-Tazobactam (JCM ed.)
April 08, 2023 07:34 - 49 minutes - 34.1 MBSusceptibility testing for piperacillin-tazobactam has undergone rapid evolution, largely driven by some surprising results from the MERINO trial, which compared the efficacy of piperacillin-tazobactam and meropenem for treatment of patients with ceftriaxone-resistant E. coli or Klebsiella pneumoniae bacteremia. We discuss how the results of the MERINO trial led to reconsideration of breakpoints for pipercillin-tazobactam at the Clinical Laboratory Standards Institute, or CLSI, how the break...
Antimicrobial Resistance in Neisseria gonorrhoeae (AAC ed.)
March 24, 2023 09:00 - 44 minutes - 30.9 MBThe Center of Diseases Control and Prevention (CDC) has categorized emergent resistance in Neisseria gonorrhoeae as an “urgent” public health problem. We discuss the emerging problem of gonorrhea and implications for public health with experts in the field Topics discussed: The clinical implications of resistance to B-lactams and quinolones in Neisseria gonorrhoeae Mechanisms of resistance in these organisms Insights into therapeutic approaches to treat resistant gonococcal infections...
Avoiding HIV False Positives (JCM ed.)
February 24, 2023 12:00 - 29 minutes - 20.4 MBWe can probably all agree that any false positive test result is bad, but I think it’s safe to say that some false positives, like a false positive HIV test for example, is much more anxiety provoking than others. And when it comes to HIV, there have been a number of key advances in the field over the past decade, include the development of improved diagnostics and optimized algorithmic approaches, all of which have allowed for earlier detection of infected patients, and particularly those w...
Discussing β-lactamase/β-lactamase inhibitors (AAC ed.)
February 10, 2023 11:00 - 51 minutes - 35.2 MBNovel β-lactamase/β-lactamase inhibitors have become critical drugs to combat the most resistant Gram-negative infections. A series of new compounds with even more broad and potent activity are in the horizon to add to the therapeutic armamentarium. Today, we will discuss these drugs with experts in the field. Topics discussed: BL/BLI combinations that are currently available in clinical practice. Future perspectives of BL/BLI armamentarium. Resistance developing for this class of ant...
Discussing β-lactamase/β-lactamase inhibitors (AAC Ed.)
February 10, 2023 11:00 - 51 minutes - 35.2 MBNovel β-lactamase/β-lactamase inhibitors have become critical drugs to combat the most resistant Gram-negative infections. A series of new compounds with even more broad and potent activity are in the horizon to add to the therapeutic armamentarium. Today, we will discuss these drugs with experts in the field. Topics discussed: BL/BLI combinations that are currently available in clinical practice. Future perspectives of BL/BLI armamentarium. Resistance developing for this class of ant...
Molecular Testing for Periprosthetic Joint Infections (JCM ed.)
January 14, 2023 00:28 - 38 minutes - 26.3 MBThe applications of large multiplex panels for detection of pathogens have greatly expanded in the past several years. Initial tests were for detection of respiratory viruses, and the first such test was labor intensive and vulnerable to frequent contamination. Since then, additional sample types have been added, such as cerebrospinal fluid and positive blood culture broths, and tests are easier to perform and reasonably reliable. We discuss a research use only multiplex PCR assay for detect...
An Update on COVID-19 Therapeutics (AAC ed.)
December 23, 2022 09:00 - 37 minutes - 25.8 MBCOVID-19 continues to pose major problems in the winter in the USA. Infections and hospitalizations are increasing and there is a fear of emergence of new variants. Therapeutic tools are also evolving. We discuss these new developments! Watch the video version via: https://youtu.be/ElnahBl53e8 Topics discussed: The latest facts on COVID Current therapeutic approaches including antivirals and monoclonal antibodies Future perspectives for the coming year on COVID-19. Guests: Adarsh ...
The Best Clinical Microbiology Papers of 2022 (JCM Ed.)
December 07, 2022 05:56 - 1 hour - 46 MBAs we enter into the holiday season, many of us look forward to celebrating long-standing traditions with family and friends, which is no different from us here on the podcast! While not necessarily as long-standing as some of the other classic holiday traditions, after 2.5 years on air, we on this podcast have established our own end-of-year tradition, which is to take a look back at some of our favorite papers or more intriguing manuscripts published in the Journal of Clinical Microbiology...
How Can Clinical Microbiology Labs Contribute to Antimicrobial Stewardship? (JCM ed.)
November 18, 2022 23:02 - 42 minutes - 29.4 MBDeciding how extensively to work up and report respiratory cultures is the worst. There are useful guidelines on how to approach this. But, in my experience, very few laboratories strictly follow these guidelines. That can be because of concerns about under-reporting pathogens or about over-reporting microbiota, or it can be the result of pressure from clinical staff to report more organisms than the guidelines suggest. Today, we’ll be talking with two guests about their study on how over-re...
Research Careers in Antimicrobial Resistance (AAC ed.)
November 05, 2022 00:00 - 42 minutes - 29.4 MBAntimicrobial resistance is the ‘silent pandemic’ and to tackle this challenging public health problem we need to attract the best and brightest. Today we will discuss pathways to work on this field with trainees who will be the next generation of outstanding researchers in the field, currently as part of different T32 training programs in the United States. Welcome to Editors in Conversation Topics discussed: Different pathways to follow careers in antimicrobial research The challenges...
Machine Learning and Artificial Intelligence in the Clinical Microbiology Laboratory (JCM ed.)
October 08, 2022 00:22 - 29 minutes - 20.2 MBThe idea of applying machine learning and digital pathology platforms to everyday workflows in the clinical microbiology laboratory has become increasing intriguing and appealing, especially as labs continue to optimize efficiency in the midst of workforce shortages. The promise of this new digital frontier is multifold, including decreasing turnaround time and potentially cost, and freeing up technologist time to focus on higher yield activities in the lab. Many labs have now taken the init...
How Proposed Change to US Regulation Could Impact Clinical Microbiology Labs (JCM ed.)
September 16, 2022 19:15 - 51 minutes - 35.2 MBThere are a number of regulatory proposals under consideration which could have important effects on clinical microbiology labs, and clinical labs more generally. First, the VALID act would change how clinical tests are regulated with particularly important implications for laboratory-developed tests. Second, the Centers for Medicare and Medicaid Services has proposed changes to the educational requirements for lab directors under CLIA and additional changes that would increase the fees that...
How Proposed Change to US Regulation Could Impact Clinical Microbiology Labs
September 16, 2022 19:15 - 51 minutes - 35.2 MBThere are a number of regulatory proposals under consideration which could have important effects on clinical microbiology labs, and clinical labs more generally. First, the VALID act would change how clinical tests are regulated with particularly important implications for laboratory-developed tests. Second, the Centers for Medicare and Medicaid Services has proposed changes to the educational requirements for lab directors under CLIA and additional changes that would increase the fees that...
Management of Mycobacterium Abscessus Infections: The Rise of a Superbug (AAC ed.)
September 02, 2022 09:00 - 42 minutes - 29.2 MBInfections caused by Mycobacterium abscessus appear to be increasing in frequency among the immunocompromised population and are challenging to treat. Antibiotic options in these cases are scarce, prolonged therapy is required and new options are needed. We will discuss this important topic with experts in the field. Topics discussed: Define M. abscessus as an opportunistic pathoge The intrinsic phenotypic characteristics of M. abscessus, including resistance to common antimicrobials ...
Management of Mycobacterium Abscessus Infections: The Rise of a Superbug
September 02, 2022 09:00 - 42 minutes - 29.2 MBInfections caused by Mycobacterium abscessus appear to be increasing in frequency among the immunocompromised population and are challenging to treat. Antibiotic options in these cases are scarce, prolonged therapy is required and new options are needed. We will discuss this important topic with experts in the field. Topics discussed: Define M. abscessus as an opportunistic pathoge The intrinsic phenotypic characteristics of M. abscessus, including resistance to common antimicrobials ...
The Inoculum Effect of Antibiotic Susceptibility Testing
August 20, 2022 00:47 - 25 minutes - 17.4 MBThe inoculum effect of antibiotic susceptibility testing is often discussed at playgrounds and infectious diseases conferences, but many of us don’t really have a clear definition of what it is or a good understanding of its importance. We’ll be talking about the inoculum effect and susceptibility testing of Staphylococcus aureus with cefazolin. Some of the questions we’ll discuss are: • What exactly is the inoculum effect and how is it measured? • Does the inoculum effect have clinica...
The Inoculum Effect of Antibiotic Susceptibility Testing (JCM ed.)
August 20, 2022 00:47 - 25 minutes - 17.4 MBThe inoculum effect of antibiotic susceptibility testing is often discussed at playgrounds and infectious diseases conferences, but many of us don’t really have a clear definition of what it is or a good understanding of its importance. We’ll be talking about the inoculum effect and susceptibility testing of Staphylococcus aureus with cefazolin. Some of the questions we’ll discuss are: • What exactly is the inoculum effect and how is it measured? • Does the inoculum effect have clinica...
Diagnosis and Treatment of Monkeypox (AAC ed.)
August 05, 2022 06:05 - 39 minutes - 27 MBAs July 26, the world has documented 19,188 cases of monkeypox, with 3,591 cases in the US alone, making the US the country with the most known infections amid the global outbreak. The WHO has declared monkeypox a public health emergency. Although this disease has been known for years, certain features suggest that we are facing a unique outbreak of monkeypox with the potential for worldwide spreading. In this special podcast edition of Editors in Conversation we will discuss the diagnosis...
Diagnosis and Treatment of Monkeypox
August 05, 2022 06:05 - 39 minutes - 27 MBAs July 26, the world has documented 19,188 cases of monkeypox, with 3,591 cases in the US alone, making the US the country with the most known infections amid the global outbreak. The WHO has declared monkeypox a public health emergency. Although this disease has been known for years, certain features suggest that we are facing a unique outbreak of monkeypox with the potential for worldwide spreading. In this special podcast edition of Editors in Conversation we will discuss the diagnosis...
Dynamite Parasites, with Dr. Bobbi Pritt (JCM ed.)
July 02, 2022 03:22 - 23 minutes - 21.4 MBDr. Bobbi Pritt aka @parasitegal, creator of the blog Creepy Dreadful Wonderful Parasites, is a pathologist and clinical microbiologist with specialty interests in parasitic and vector-borne infections, and the pathology of infectious diseases. Dr. Pritt discusses her career and how she became an expert in clinical parasitology, her work internationally and how others can participate in global health work and how technology (digital pathology, AI, automation, etc.) will affect the lab and...
Stenotrophomonas maltophilia: The Silent Rise of a Superbug (AAC ed.)
June 18, 2022 04:17 - 28 minutes - 19.4 MBInfections caused by Stenotrophomonas maltophilia appear to be increasing in frequency among the immunocompromised population and are challenging to treat. Moreover, resistance to traditional drugs used against these organisms is now becoming more common. Antibiotic options in these circumstances are scarce and new options are needed. We discuss this important topic with experts in the field. Recorded live in Washington DC at ASM Microbe 2022. Topics • Stenotrophomas maltophilia as an op...
What’s New in Molecular Virology? (JCM ed.)
May 28, 2022 06:22 - 41 minutes - 28.6 MBWe are just back from the Molecular Virology Workshop in West Palm Beach. This is a terrific meeting that is organized by the Pan-American Society for Clinical Virology or PASCV. The workshop immediately precedes the Clinical Virology Symposium that ASM organizes and many of us like to attend both. Today we’ll be talking about some of the high points of the Molecular Virology Workshop, with two members of the organizing committee from PASCV. Guests: Dr. Erin Graf, Director, Clinical Micro...
What’s New in Molecular Virology?
May 28, 2022 06:22 - 41 minutes - 28.6 MBWe are just back from the Molecular Virology Workshop in West Palm Beach. This is a terrific meeting that is organized by the Pan-American Society for Clinical Virology or PASCV. The workshop immediately precedes the Clinical Virology Symposium that ASM organizes and many of us like to attend both. Today we’ll be talking about some of the high points of the Molecular Virology Workshop, with two members of the organizing committee from PASCV. Guests: Dr. Erin Graf, Director, Clinical Micro...
Treatment of Resistant Pseudomonas Aeruginosa Infections (AAC ed.)
May 14, 2022 06:08 - 52 minutes - 36 MBInfections caused by multidrug-resistant Pseudomonas aeruginosa are considered a major public health problem. Antibiotic options are scarce but new drugs are emerging and more maybe available in the near future. Topics discussed: Pseudomonas aeruginosa as an important pathogen capable of developing resistance to multiple antibiotics Common mechanisms of resistance in Pseudomonas aeruginosa The current and future approaches for these MDR organisms. Guests: Michael Satlin, MD, Associa...
Prevalence and Mortality Associated with Bloodstream Infections (JCM ed.)
April 29, 2022 17:47 - 29 minutes - 20.4 MBIt is estimated that anywhere from 575,000 to 677,000 bloodstream infections occur annually in North America, with approximately 40,000 of those directly linked to patient mortality in the United States, making bloodstream infections the 11th most common cause of death in the US according to the Centers for Disease Control and Prevention. The detection of bloodstream infections and subsequent identification of the etiologic agent or agents is an essential role played by all clinical microbio...
Consensus on B-lactamases (AAC ed.)
April 05, 2022 13:00 - 41 minutes - 28.8 MBThis episode is dedicated to the memory of the late George A. Jacoby, who was a pillar in the B-lactamase research community and a leader in the field of antimicrobial resistance. Assigning names to b-lactamase variants has been inconsistent and has led to confusion in the published literature. The common availability of whole genome sequencing has resulted in an exponential growth in the number of new b-lactamase genes. In November 2021 an international group of b-lactamase experts met v...
Multiplex PCR for Predicting Antibiotic Susceptibility (JCM ed.)
March 19, 2022 02:59 - 40 minutes - 28 MBAntibiotic susceptibility testing is too slow. Faster identification of microorganisms is now common, as many laboratories use MALDI-TOF or molecular technologies for quick and definitive identification of bacteria. Improvements in susceptibility testing have lagged, as we continue to use tests that take a day for results, and which have not significantly changed in decades. Rapid phenotypic testing has can only be done on limited sample types, using a dedicated platform, and it has not been...
Phages as Therapeutic Tools Against Multidrug Resistant Bacteria (AAC ed.)
March 05, 2022 00:40 - 43 minutes - 30 MBBacteriophages are interesting viruses that target bacteria and have been used for therapeutic purposes. Recently, the emergence of antibiotic resistance has spurred a renewed interest in using these viruses or their products as therapeutic tools against recalcitrant human pathogens. AAC has also published a recent manuscript from ARLG to guide the use of phages in clinical practice. We will discuss with experts in the field the state-of-the-art in phage therapy. Objectives: • Understand...
COVID-19 Associated Pulmonary Aspergillosis - The Other CAPA (JCM ed.)
February 18, 2022 12:00 - 46 minutes - 31.9 MBWhen most of us hear the word ‘CAPA’, these days we more than likely immediately start thinking about SARS-CoV-2 variants, trying to remember how important this particular one was in the grand scheme of the COVID-19 pandemic. But, that is not the ‘kappa’ we will be talking about today. Instead, we’ll be discussing the other CAPA, or COVID-19 Associated Pulmonary Aspergillosis, and we will cover a few areas on this topic, including: - Defining what CAPA is and how prevalent it is among ICU ...
WHO, Critical Review, of the Antibacterial Pipeline (AAC ed.)
January 28, 2022 23:16 - 42 minutes - 28.9 MBAAC just published a review from the WHO advisory panel on the antibacterial pipeline analyzing ‘traditional’ and ‘non-traditional’ antibacterial agents and modulators in clinical development current on 30 June 2021 with activity against the WHO priority pathogens, mycobacteria and Clostridioides difficile. Today, we will dissect this important publication Objectives: • Understand the role of the WHO in antimicrobial resistance • Discuss the analysis of the antibacterial pipeline • Del...
WHO Critical Review of the Antibacterial Pipeline (AAC ed.)
January 28, 2022 23:16 - 42 minutes - 28.9 MBAAC just published a review from the WHO advisory panel on the antibacterial pipeline analyzing ‘traditional’ and ‘non-traditional’ antibacterial agents and modulators in clinical development current on 30 June 2021 with activity against the WHO priority pathogens, mycobacteria and Clostridioides difficile. Today, we will dissect this important publication Objectives: • Understand the role of the WHO in antimicrobial resistance • Discuss the analysis of the antibacterial pipeline • Del...