We are joined by Dr Matthew Nagra to dive into animal-free nutrition. We take a dive into conditionally essential amino acids, wound healing, depression, vitamin B12, gut health and debunk a few claims along the way. Let's learn

00:00 Intro
00:43 Are conditionally essential amino acids ever essential ?
03:42 Are vegans at risk of reduced wound healing ?
04:17 How much choline do we need per day ?
05:53 Claim: Aim for 2000 mg of choline per day (Dr Andew Huberman)
07:14 Potential polymorphism for considerations
08:16 Is elevated homocysteine a causal risk factor or a just a marker ?
09:14 Claim: Vegan mothers have a placenta of a smoker (CarnivoreMD)
15:46 Are vegans at risk of depression ?
20:08 Can we train our gut to get used to fibre ?
24:07 How long can you survive without B12 ?
25:37 The Blood Type Diet: Science or Fiction ?
28:12 Facts about Dr Matthew Nagra
32:31 Outro

References & Resources Mentioned:

Concept of Conditionally Essential Amino Acids
https://www.cambridge.org/core/books/abs/neonatal-nutrition-and-metabolism/conditionally-essential-nutrients-choline-inositol-taurine-arginine-glutamine-and-nucleotides/0378571060A6F0EEE8034DDA79CAEFF1

Pregnancy
https://link.springer.com/article/10.1007/s00404-020-05689-xhttps://obgyn.onlinelibrary.wiley.com/doi/10.1111/1471-0528.13280https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561836/https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/overall-plantbased-diet-index-during-pregnancy-and-risk-of-gestational-diabetes-mellitus-a-prospective-cohort-study-in-china/B932430D76DCD86FA14C5363AF11893C

VeChi Studies
https://link.springer.com/article/10.1007/s00394-021-02753-3https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157583/

Choline Studies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303951/https://pubmed.ncbi.nlm.nih.gov/35575618/

Facts on Choline
https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/https://www.eatforhealth.gov.au/nutrient-reference-values/nutrients/cholinehttps://pubmed.ncbi.nlm.nih.gov/23193625/https://pubmed.ncbi.nlm.nih.gov/26886842/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637180/

The following paper is where the Choline AI came from:
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.5.7.2010061

Video from Huberman Lab with the claim made on choline
https://www.youtube.com/watch?v=E7W4OQfJWdw

Vegan sources of choline: https://www.pinterest.ch/pin/474426141997872811/

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases
https://pubmed.ncbi.nlm.nih.gov/25449138/#:~:text=The%20Methylenetetrahydrofolate%20reductase%20(MTHFR)%20C677T,on%20the%20geography%20and%20ethnicity.

The Liver King Lie
https://www.youtube.com/watch?v=BKpmAGZQetchttps://pubmed.ncbi.nlm.nih.gov/36841216/

Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis
https://pubmed.ncbi.nlm.nih.gov/29551598/

Paul Salodino & Liver King talking about selling supplements
https://www.youtube.com/watch?v=eLTMuX5wloU


Mental Health & depression
https://www.tandfonline.com/doi/epdf/10.1080/10408398.2020.1741505?src=getftr
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466124/
https://academic.oup.com/nutritionreviews/article/80/2/242/6209457?login=true

Kevin Klatt thread on choline:
https://twitter.com/KCKlatt/status/1626246629941743617?s=20


Gut Health & Fiber
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228670/#:~:text=A%20small%20percentage%20(3%2D11,diets%20without%20flatulence%2Dproducing%20components.
https://www.sciencedirect.com/science/article/pii/S0002916522028131?via%3Dihub

Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504379/

The Blood Type Diet: Science or Fiction?
https://drmatthewnagra.com/the-blood-type-diet-science-or-fiction/
https://pubmed.ncbi.nlm.nih.gov/15229195/
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084749

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