Last Week in Medicine
72 episodes - English - Latest episode: 10 months ago - ★★★★★ - 40 ratingsWouldn't it be nice if someone reviewed all the latest internal medicine literature and distilled it into a brief podcast you could listen to on your way to work? Get updates from the New England Journal of Medicine, JAMA Network, Annals of Internal Medicine, Journal of Hospital Medicine, Journal of General Internal Medicine, Lancet and more.
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Episodes
Long Acting Injectable Therapy for HIV and Pregnenolone for Chronic Low Back Pain
March 10, 2020 23:00 - 25 minutes - 17.3 MBAustin finally returns to the podcast with harrowing tales of almost being eaten by a wolf. Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Long Acting Cabotegravir and Rilpivirine for HIV-1 Pregnenolone vs Placebo for Chronic Low Back Pain in Veterans Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://inco...
Long Acting Injectable Therapy for HIV and Pregnenolone for Chronic Low Back Pain
March 10, 2020 23:00 - 25 minutes - 17.3 MBAustin finally returns to the podcast with harrowing tales of almost being eaten by a wolf. Today we discuss a new NEJM paper about long acting injectable therapy for HIV and a new JAMA paper about pregnenolone, a neurosteroid that may help treat the scourge of primary care: chronic low back pain. Long Acting Cabotegravir and Rilpivirine for HIV-1 Pregnenolone vs Placebo for Chronic Low Back Pain in Veterans Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://inco...
COVID-19, PPI Use and MDRO Colonization, Hospitalist Care of ED Boarders
March 04, 2020 01:00 - 32 minutes - 22.6 MBToday we had Dr. Dani Babbel back on the show to talk about the latest COVID-19 updates, whether gastric acid suppression increases your risk of MDRO colonization, and how to improve care to patients boarding in the emergency department. Check it out! Characteristics of Covid-19 in China Covid-19 Report from CDC of China Gastric Acid Suppression and MDRO Colonization Hospitalist Care of ED Boarders and Length of Stay Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod ...
COVID-19, PPI Use and MDRO Colonization, Hospitalist Care of ED Boarders
March 04, 2020 01:00 - 32 minutes - 22.6 MBToday we had Dr. Dani Babbel back on the show to talk about the latest COVID-19 updates, whether gastric acid suppression increases your risk of MDRO colonization, and how to improve care to patients boarding in the emergency department. Check it out! Characteristics of Covid-19 in China Covid-19 Report from CDC of China Gastric Acid Suppression and MDRO Colonization Hospitalist Care of ED Boarders and Length of Stay Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod ...
Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia, High Consulting Hospitalists, Medicare for All
February 25, 2020 02:00 - 31 minutes - 21.9 MBToday we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy. She gives us a master class in propensity weighted analysis and instrumental variable analysis. We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the U...
Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia, High Consulting Hospitalists, Medicare for All
February 25, 2020 02:00 - 31 minutes - 21.9 MBToday we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy. She gives us a master class in propensity weighted analysis and instrumental variable analysis. We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the U...
Plasma Exchange and Glucocorticoids for ANCA-Vasculitis and Dexamethasone for ARDS, aka the PLEX and DEX episode
February 19, 2020 01:00 - 31 minutes - 21.4 MBToday we have the venerable EBM guru Dr. Brian Locke on the show to talk PLEX and DEX. Does plasma exchange for ANCA-vasculitis really work? Do steroids make any difference in patients with ARDS? Also, have you ever wondered which Hogwarts house your medical specialty belongs to? Plasma Exchange and Glucocorticoids for ANCA-Vasculitis Dexamethasone for Acute Respiratory Distress Syndrome The Sorting Hat of Medicine: Why Hufflepuffs Wear Stethoscopes and Slytherins Carry Scalpels Mus...
Aspirin for VTE Prophylaxis after THA or TKA, Fluid Management for Sepsis in Patients with ESRD, Cirrhosis and CHF
February 11, 2020 22:00 - 29 minutes - 20 MBToday we are joined by the man, the myth, and the legend, Dr. Stacy Johnson, to talk about a new meta-analysis of using aspirin for DVT prophylaxis after a total hip or knee replacement. We also review a new retrospective cohort study from Cleveland Clinic on whether it's safe to give the recommended 30 ml/kg fluid bolus to patients with sepsis who also have CHF, cirrhosis or ESRD. Check it out! Aspirin for VTE Prophylaxis after THA or TKA Fluid Management for Sepsis in Patients with E...
CT Screening for Lung Cancer, Conservative vs Interventional Treatment for Spontaneous Pneumothorax
February 04, 2020 03:00 - 28 minutes - 19.9 MBToday we are joined by the very smart Dr. Jason Carr, a pulmonary/critical care fellow, to talk about two big papers from the wonderful world of lungs. Does CT screening for lung cancer save lives? Do you have to put a chest tube in every patient with a spontaneous pneumothorax? Check it out! CT Screening for Lung Cancer, AKA NELSON Conservative vs Interventional Treatment for Spontaneous Pneumothorax Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompete...
CT Screening for Lung Cancer, Conservative vs Interventional Treatment for Spontaneous Pneumothorax
February 04, 2020 03:00 - 28 minutes - 19.9 MBToday we are joined by the very smart Dr. Jason Carr, a pulmonary/critical care fellow, to talk about two big papers from the wonderful world of lungs. Does CT screening for lung cancer save lives? Do you have to put a chest tube in every patient with a spontaneous pneumothorax? Check it out! CT Screening for Lung Cancer, AKA NELSON Conservative vs Interventional Treatment for Spontaneous Pneumothorax Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompete...
Novel Coronavirus, High Sensitivity Troponins, Hydroxyethyl Starch for Abdominal Surgery and Testosterone Therapy in Men
January 28, 2020 04:00 - 27 minutes - 19 MBIt's our tenth episode! Thanks for getting us this far. Today we discuss the new coronavirus outbreak, what to do with high sensitivity troponins, whether hydroxyethyl starch should be used in abdominal surgery (spoiler alert: it shouldn't) and the appropriate use of testosterone therapy. Novel Coronavirus in China High Sensitivity Troponins and the Fourth Universal Definition of MI Hydroxyethyl Starch versus Saline in Major Abdominal Surgery Efficacy and Safety of Testosterone Treatm...
Factor XIa Inhibition for VTE Prophylaxis, Physician Time Using EHR in Outpatient Encounters, Vitamin C and Thiamine for Septic Shock
January 22, 2020 03:00 - 30 minutes - 21.1 MBToday we are joined by the wonderful Dr. Emily Signor to talk about new therapeutic approaches to DVT prophylaxis, how much time physicians spend using the EHR in clinic, and whether that Vitamin C cocktail works for septic shock. Check it out! Effect of Osocimab in Preventing VTE in Patients Undergoing TKA Physician Time Spent Using the EHR During Outpatient Encounters Vitamin C, Thiamine and Hydrocortisone for Septic Shock Music from https://filmmusic.io "Sneaky Snitch" by Kevin Mac...
Health Care Hotspotting, Valve Replacement in Asymptomatic Very Severe Aortic Stenosis, Free Medications and Treatment Adherence
January 14, 2020 02:00 - 32 minutes - 22 MBToday we try something a little different -- three co-hosts! Dr. Dani Babbel joins Jenkins and Rupp for some lively discussion about hotspotting, very severe aortic stenosis and whether adherence improves when medications are free. Check it out! Health Care Hotspotting Early Surgery for Asymptomatic Aortic Stenosis Effect on Treatment Adherence of Distributing Essential Medicines at No Charge Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) L...
Hospital Care at Home, Adverse Events in “Social" Admissions, NT-ProBNP Before Non-Cardiac Surgery, Alcohol Abstinence in Drinkers with Atrial Fibrillation
January 07, 2020 03:00 - 35 minutes - 24.1 MBHappy New Year and welcome to the first episode of 2020! We've got some great articles to review today. Can we save money by taking care of some acutely ill patients in their own homes? Are patients admitted for "social" reasons at the same risk for adverse events as acutely ill patients? Can NT-ProBNP level predict cardiovascular death and myocardial injury after non-cardiac surgery? Does limiting alcohol intake reduce atrial fibrillation recurrence? Listen to find out! Hospital Lev...
Gadolinium in CKD Stage 4 and 5, Metoprolol and COPD Exacerbations, Vitamin D in Critically Ill Patients, Politics and Mood in Young Physicians
December 17, 2019 04:00 - 25 minutes - 17.3 MBDr. Rupp is back! Today we talk about whether it's safe to give group 2 gadolinium based contrast agents to patients with CKD stage 4 and 5 and whether metoprolol can be used to prevent COPD exacerbations. We also shine some more sunlight on the sunshine vitamin's inability to change any meaningful outcomes, and discuss some interesting data from the Intern Health Study. Risk of Nephrogenic Systemic Fibrosis in Patients with Stage 4 or 5 CKD Receiving Group II Gadolinium Based Contrast Ag...
Upper GI Bleeding Guidelines, E-cigarette and Vaping Associated Lung Injury, Beta Blockers and HFpEF Exacerbations
December 10, 2019 05:00 - 30 minutes - 20.8 MBThis week we have a special guest host, Dr. Dani Babbel. We talk about the new guidelines on upper GI bleeding, a new study on E-VALI, and the possible association of beta blockers with heart failure hospitalizations in heart failure with EF > 50%. Management of Upper GI Bleeding Guidelines Clinical presentation, treatment and short term outcomes of E-VALI Association of Beta-Blocker Use with Heart Failure Hospitalizations in HFpEF Music from https://filmmusic.io "Sneaky Snitch" by Kev...
D-dimer Adjusted for Clinical Probability of PE, Work Schedules of Hospitalists, Inappropriate Fluoroquinolone Prescribing, Utilization and Outcomes of Lytics in Acute PE
December 02, 2019 19:00 - 24 minutes - 16.6 MBCan you get away with a higher d-dimer value in patients with a low pre-test probability for PE? Does working more days in a row improve patient outcomes? How often are people inappropriately prescribing fluoroquinolones? How often are people using systemic lytics vs catheter directed lytics in acute PE, and what are the outcomes? Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (http://creativecommons.org/licenses/by/4.0/)
D-dimer Adjusted for Clinical Probability of PE, Work Schedules of Hospitalists, Inappropriate Fluoroquinolone Prescribing, Utilization and Outcomes of Lytics in Acute PE
December 02, 2019 19:00 - 24 minutes - 16.6 MBCan you get away with a higher d-dimer value in patients with a low pre-test probability for PE? Does working more days in a row improve patient outcomes? How often are people inappropriately prescribing fluoroquinolones? How often are people using systemic lytics vs catheter directed lytics in acute PE, and what are the outcomes? Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (http://creativecommons.org/licenses/by/4.0/)
Vitamin D in Diabetic Kidney Disease and SGLT-2 Inhibitors for Heart Failure Reduced Ejection Fraction
November 26, 2019 03:00 - 23 minutes - 16.4 MBToday we talk about the effects of vitamin D in progression of CKD in people with diabetes, and whether SGLT-2 inhibitors like dapagliflozin can be used to treat heart failure with reduced ejection fraction in people without diabetes. We also talk about ticagrelor monotherapy after three months of DAPT, rivaroxaban for the treatment of APS (don't do it!) and LDL targets for stroke prevention. Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) Licen...
The Apple Heart Study, Colchicine after MI
November 19, 2019 04:00 - 23 minutes - 15.9 MBLots of cardiology to discuss this week with the Apple Heart and COLCOT studies, both published in the New England Journal of Medicine. We also talk about the 3 Wishes Project, the net clinical benefit of oral anticoagulation with aging over 75, the benefits of non-pharmaceutical treatment of agitation, and getting blood cultures before you give antibiotics. Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (http://creativecommons.or...
Intensifying blood pressure therapy, asymptomatic bacteriuria, DRIP score in pneumonia
November 12, 2019 05:00 - 29 minutes - 20.6 MBShould we add blood pressure medications or increase the dose while patients are in the hospital? What are the risk factors and outcomes for people who receive antibiotics for asymptomatic bacteriuria? And how does the DRIP score stack up against previous tools for identifying patients at high risk for drug resistant pneumonia? Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (http://creativecommons.org/licenses/by/4.0/)
Intensifying Blood Pressure Therapy in the Hospital, Asymptomatic Bacteriuria, DRIP score in Pneumonia
November 12, 2019 05:00 - 29 minutes - 20.6 MBShould we add blood pressure medications or increase the dose while patients are in the hospital? What are the risk factors and outcomes for people who receive antibiotics for asymptomatic bacteriuria? And how does the DRIP score stack up against previous tools for identifying patients at high risk for drug resistant pneumonia? Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (http://creativecommons.org/licenses/by/4.0/)