Lab Medicine Rounds
124 episodes - English - Latest episode: 13 days ago - ★★★★★ - 15 ratingsA Mayo Clinic podcast for laboratory professionals, physicians, and students, hosted by Justin Kreuter, M.D., assistant professor of laboratory medicine and pathology at Mayo Clinic, featuring educational topics and insightful takeaways to apply in your practice.
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Episodes
Preparing for Lab Week: Celebrating Laboratory Successes
April 15, 2022 05:00 - 23 minutes - 21.7 MBTimestamps: 0:00 Introduction 1:00 Why is it important to look at the past when planning for the future? 4:30 Keeping in mind our audience, we've got laboratorians, we've got pathologists, we have other physicians from the health care team listening, what might be a good resource, or what would you recommend to be aware of these larger trends? 6:50 What are one or two aspects of pathology and laboratory medicines past that you are interested in celebrating this lab week? 8:58 How d...
Magic in Medicine
April 01, 2022 05:00 - 25 minutes - 23.3 MB00:00 Intro 01:02 How did you get started in magic? 03:57 How does this roll into your practice as an Anatomic Pathologist? How do you see this skill translate? 06:29 What is a mentalist? 11:05 How do you approach teaching our residents and fellows about how they might think about and use magic in their practice? 14:20 How can we get better at suspending that belief for our residents without getting caught up in the nitty gritty? 16:15 What would an ACGME milestone on magic...
Wellness: What's Your Why?
March 18, 2022 05:05 - 21 minutes - 19.8 MB00:00 Intro 00:58 Why are wellness efforts a need-to-have, rather than a want-to-have? 04:18 What are we learning about wellness that is important for our audience to understand? 07:44 What are those first steps that our listeners can take and initiate for their own local practice, what would their initial support look like? 14:23 Are there classic struggles with improving wellness that you can help our listeners navigate if there are some pearls to share in that regard? 22:01 ...
The Laboratory’s Role in Health and Equity
March 04, 2022 06:00 - 20 minutes - 18.5 MBTimestamps: 00:00 Intro 01:23 Why is health equity important for laboratory medicine and pathology? 03:13 What are we learning about how as a laboratory we may better advocate for health equity? 05:27 What’s the nuance there that we need to grapple with, not just more testing but better testing? 08:30 Are there examples of how we can do this better from other professions that we can learn from? 09:59 Is that something that you feel with your previous experience as a hematopa...
The Value of Pathology Interest Groups
February 18, 2022 06:00 - 25 minutes - 23 MBTimestamps: 00:00 Intro 01:32 From your points of view, why do you think it’s important to start a pathology interest group? 07:24 What are some important elements that you think are important for a successful interest group in your experience? 11:24 Is there one or two activities that really stands out that’s been perceived as the most valuable and best experiences so far? 13:18 Has there been any challenge with some faculty being able to explain or demonstrate their work, or ...
Six Questions
February 04, 2022 06:00 - 8 minutes - 7.64 MBWe appreciate any feedback you have time to provide, in order to inform the future of the "Lab Medicine Rounds" podcast. No questions are required. Please take the short, anonymous, six question survey here: https://surveys.mayoclinic.org/jfe/form/SV_di0Wjubj6GAce10
The Importance of Interprofessional Education
January 21, 2022 06:05 - 21 minutes - 19.7 MBTimestamps: 00:00 Intro 01:05 From your perspective, why is interprofessional education an important for us clinicians, lab medicine colleagues, and students? 04:18 What are a few of those key lessons that you’ve learned about how to do this interprofessional education? 07:15 How do you think we make it a meaningful experience for the students? 10:37 What sort of approach do you take to feedback, to get that feedback that’s really going to help you meaningfully iterate in a po...
Responding With Grace While Under Pressure
January 07, 2022 06:00 - 17 minutes - 16.4 MBTimestamps: 00:00 Intro 02:00 Why is it important to respond with grace while we’re under pressure? 03:36 How do you think you develop this ability to project poise when in stressful situations? 05:33 Was there a mentor, situation, or experience where it gave you pause and made you think, “Wow, that’s somebody that really showed grace under pressure and leadership abilities.” Is there anybody in your life who comes to mind? 07:15 Did you find yourself having some of these ment...
The ultimate gift: Organ transplantation
December 17, 2021 06:00 - 18 minutes - 16.6 MBTimestamps: 00:00 Intro 01:05 How did you first get interested in supporting organ transplantation? 04:53 What are the organs that we can transplant? 06:00 When we are at the Department of Motor Vehicles, we can register as a donor and make our wishes known to our family, is that right? 07:03 If people are interesting in donating a kidney, for example, do they reach out to their local hospital and let them know they are interested in being a donor? 08:50 How does your work in...
Valley fever testing: Right test, right time, right patient
December 03, 2021 06:00 - 20 minutes - 18.6 MBTimestamps: 00:00 Intro 01:24 Why does clinical context matter for what test clinicians order? 08:41 What determines what kind of test to order? 13:07 How does the communication happen between the lab and the clinician? How should it happen to provide best care for the patient? 18:21 What do you think about for the future of ordering laboratory tests? 21:59 Outro
Pathologist's role in medical education
November 19, 2021 06:05 - 26 minutes - 24.6 MBTimestamps: 00:00 Intro 00:48 What’s your origin story? How did you get interested in medical school education? 06:18 What are we learning about better ways to educate? 13:42 How can faculty make it a safe environment? How can we get students to give it a try? 16:25 How do you bring about and navigate curricular change? 20:15 Was there something that you did that prepared you for this role? Is there some advice for people who are interested in taking a leadership role in educ...
Residency interview process
November 05, 2021 06:00 - 17 minutes - 16.5 MBTimestamps: 00:00 Intro 01:07 Why is it so challenging to ask questions in an interview? 03:19 Can you go over what are a few aspects that somebody can ask about? 04:41 What was your process when you made your list, that cheat sheet, the actual how we’re doing of formulating a question. What was your approach there? 05:54 Are there any interesting questions you’ve gotten from applicants over the years that really stood out to you? Conversely, what are some questions that you th...
Lessons learned: Navigating the COVID-19 pandemic
October 22, 2021 05:00 - 18 minutes - 17.3 MBTimestamps: 00:00 Intro 01:22 Why is it important for labs to learn from their COVID-19 experiences? 05:34 Did you have any other lessons learned from this experience? 8:31 How are these meetings focused on maintaining a high quality? How did you manage the rest of your workload (developing new tests, etc.)? 12:51 Have some of those lessons from the experience of how those meetings were run, is there anything that you’re taking forward that you hadn’t been doing before COVID? ...
Being a professional on social media: Challenges and opportunities
October 08, 2021 05:00 - 18 minutes - 16.6 MBTimestamps: 00:00 Intro 01:02 What are a few of the potential risks and benefits of using social media as a professional? Why should I be doing this and thinking about it? 03:31 People can adjust their privacy settings on social media, so why is it important for healthcare professionals and students to behave professionally on social media? 06:08 Some might say that there are several shades of gray when it comes to professionalism. So, what do we need to understand about profes...
Cytopathology: Cases, challenges, and advancements
September 24, 2021 05:00 - 22 minutes - 21.1 MBIn this episode of Lab Medicine Rounds, Chris Hartley, M.D., Assistant Professor of Laboratory Medicine and Pathology at Mayo Clinic, discusses the topic of cytopathology, and what some of the challenges and advancements are.
Thrombotic thrombocytopenic purpura (TTP): Why it’s important to understand it
September 17, 2021 05:00 - 20 minutes - 18.6 MBDisclosure of relevant financial relationship: Dr. Mazepa received honoraria from Sanofi. Timestamps: 00:00 Intro 00:52 Why is it important for physicians to have some understanding about TTP? 04:26 What’s new in this immune TTP area? 08:57 If you have a new patient show up, you do caplacizumab and plasma exchange together or are there certain patient populations, like certain characteristics who would or would not get this medication? 11:29 I was wondering if you could elabo...
Reversal of DOACs: Making critical advancements
September 10, 2021 05:00 - 23 minutes - 21.2 MBTimestamps: 00:00 Intro 00:43 Why is it important for physicians to understand about the reversal of these direct oral anticoagulants? 03:09 The complications or the bleed rate was a lot less, with these direct oral anticoagulants? 03:57 Although there is less severe bleeding, there was a concern by patients and physicians about, if it is severe, what is the plan? 04:51 What have we learned new? Are we learning more about what patient population to use them in, as well as the ...
Rapid reference laboratory development
September 03, 2021 05:00 - 14 minutes - 13.4 MBTimestamps: 00:00 Intro 01:10 Why is reference laboratory testing important for physicians and laboratorians to understand? 02:00 No lab does all the testing in their own laboratory. Labs can’t really have a whole panel of laboratory tests; it just doesn’t make sense, right? 04:39 What have we learned in the last couple years about reference laboratories, how we can best support clinical practice? 06:10 Do you have an insight for how that communication goes? 8:46 How might a h...
Perspectives from a visiting medical student: Path to success
August 27, 2021 05:00 - 19 minutes - 18.1 MBTimestamps: 00:00 Intro 01:15 Why are external rotations in pathology important from the student perspective? 03:51 Do you get to understand the particulars of a program or maybe what kind of questions you might be asking when you later interview because you do a rotation? 05:03 What is unique from an international perspective? 07:53 Can you compare and contrast the in-person pathology elective, with some of the virtual resources that are available at this point and time? 11...
COVID-19 laboratory innovations: Sequencing and diagnostics
August 20, 2021 05:00 - 14 minutes - 13.4 MBTimestamps: 00:00 Intro 00:44 With this latest outbreak of the Delta variant with COVID-19, are laboratorians still working on new innovations for COVID? 02:23 Could you go into more detail, elaborate for us about this COVID-19 innovation around sequencing? 04:25 Could you help us understand a little bit on what work is being done in those areas? 07:47 Could you help our audience understand what have these conversation been like now that we’re into this pandemic this far, and...
Addressing the national blood shortage: Why blood inventory is so important
August 06, 2021 05:00 - 21 minutes - 20.2 MBTimestamps: 00:00 Intro 01:05 From your perspective, why is the blood inventory important to a hospital? 04:17 What have you learned about managing a hospital’s blood inventory these past 18 months or so? 08:09 I was wondering if you could give us a specific example on how are they trying to bridge that gap? 08:55 Can you explain who the Dream Team is? 12:34 How does PVM look different on the hospital side? How is that being worked? 16:33 How might physicians, non-pathologis...
What should learners focus on during training?
July 23, 2021 05:00 - 24 minutes - 22.6 MBTimestamps: 00:00 Intro 02:15 Why is it not enough for learners just to focus on the curriculum of their program? 04:30 What are two or three things that learners should pay attention to during their training? 07:19 Paying attention to the habits of our mentors and understanding that those habits are what is reassuring them, that is a key source for their confidence in their clinical practice. What’s another thing? 09:50 Do you have a third one that we should pay attention to? ...
Understanding medical ethics
July 09, 2021 05:00 - 26 minutes - 24.2 MBTimestamps: 00:00 Intro 01:19 Could you help us understand, why should I consider getting an ethics consult? What value could this bring to my clinical practice? 07:49 What should our audience understand in order to really work better with our local med ethics team? 13:58 Could you help us understand about organizational ethics? How does that compare and contrast with that hospital ethics committee that you said everybody has and are most used to turning to? 22:24 What would be...
Hereditary oncology: Molecular testing for solid tumors
June 18, 2021 05:00 - 21 minutes - 19.4 MBTimestamps: 00:00 Intro 00:45 Why is it important to perform molecular testing on solid tumors? 02:47 What is the significance of this testing for the patients and physicians? 07:18 Can you share with us, what are some recent examples that have blown this door open about hereditary oncology? 10:28 Can you talk a little bit about the challenge on how do we get the rapid rise in molecular knowledge and testing? What is your perspective? 15:25 Can you elaborate a little bit on ho...
Frozen sections: Value & challenges
June 04, 2021 05:00 - 25 minutes - 23.3 MBTimestamps: 00:00 Intro 01:11 What are frozen sections, and why are they an important part of patient care? 04:50 What are some of the challenges of actually performing a frozen section diagnosis? 07:03 How has frozen section changed in recent years, or over the course of practice? Has it been practiced similarly over the years, and are there differences in frozen section practice in different hospitals? 14:37 Given this uptick in the complexity of cases, how do you mentor peop...
Cardiovascular laboratory: Biomarkers, testing, & clinical implications
May 21, 2021 05:00 - 18 minutes - 17.2 MBTimestamps: 00:00 Intro 01:00 How does the cardiovascular laboratory support patient care? 01:47 Can you tell us a bit about ceramides? What are they? 04:14 When should ceramides be tested? 06:04 Can you modify someone’s ceramides such that the test can be repeated and monitored, or is it once in a lifetime because ceramides or more static? 08:05 What is the controversary around ceramides? 09:52 Could you give our listeners an introduction to Lipoprotein(a)? 11:45 Who shou...
Sustainable bridges: Lab medicine & cardiology
May 07, 2021 05:00 - 19 minutes - 17.7 MBTimestamps: 00:00 Intro 01:00 Can you give us the lay of the land and explain how does the cardiovascular laboratory provide patient care? 03:24 Can you elaborate for us what it looks like when you have clinical chemists, cardiologists, and other professionals with different backgrounds working together? 05:56 Can you talk about bringing these people into the laboratory and developing a test that provides a lot of value to patients? How is that blended and what’s the output? 07...
Forensic pathology 101
April 16, 2021 06:00 - 21 minutes - 19.7 MB00:00 Intro 01:15 What’s your origin story? How did you become a forensic pathologist? 03:53 What are some of the misconceptions about forensic pathology? 06:15 Is there a big public health component to forensic pathology? 07:29 Covid is a nice example on how you have partnered with public health, can you elaborate more on that? 10:15 What other types of physicians are you interacting with periodically and what are those conversations about? 13:10 Do you approach autopsies d...
Cultivating quality in the clinical practice
April 02, 2021 05:00 - 24 minutes - 22.4 MBTimestamps: 00:00 Intro 01:29 Why is it really important for leaders in our practice to really understand quality for clinical practice? 03:13 What are the latest developments in your area of clinical laboratory medicine? 06:01 In recent years, what have we learned about quality and how we do quality in the hospital? 11:19 How do we actually implement this in clinical practice for success, for sustainability? You talked about putting together an interdisciplinary team. What’s t...
Toxicology testing for patient care
March 19, 2021 05:00 - 23 minutes - 21.3 MB00:00 Intro 00:40 Can you tell us how your roles in these different laboratories support testing for patient care? 03:13 What are the latest developments in your area of clinical laboratory medicine? 07:22 Can you elaborate a little bit about this new approach that you have developed is able to bring both sensitivity and specificity along? 10:55 Putting the interpretation on the form, you are probably experiencing quite a few phone calls with our clinical colleges. Can you talk ...
Transfusion support of ECMO patients
March 05, 2021 06:00 - 17 minutes - 16.3 MBTimestamps: 00:00 Intro 01:07 Why is transfusion support an especially important component of patient care for patients that are on ECMO support? 03:24 Are there some principles that we can think about that will help us better understand transfusion decisions in these patients? 05:52 Can you take us through some specific situations that might help our listeners get our hands around (DO2 and VO2) from a practical standpoint? 10:31 How can laboratory professionals add value to t...
Laboratory & critical care: Opportunities for collaboration
February 19, 2021 06:00 - 17 minutes - 16.1 MBTimestamps: 00:00 Intro 01:11 As a critical care physician, why is laboratory testing important for your practice? 04:09 What do you wish lab medicine folks understood better about critical care medicine? 08:19 What would be your advice to a laboratory medical professional that’s interested in developing a better understanding of critical care medicine? 14:51 What do you see for the future collaboration between laboratory medicine and critical care practice? 16:44 Outro
Let's talk cellular therapy
February 05, 2021 06:00 - 16 minutes - 14.8 MB00:00 Intro 01:15 From your perspective, why is cellular therapy an important topic for our listeners? 02:55 What is your origin story into this world of cellular therapy? 06:20 Working in such a fast-paced area, what has been a unique challenge you have had to navigate and how have you done that? 08:05 Keeping up with the literature can be a challenge, and once you are out of training you don’t have those deadlines of “have you read your recent articles for the month.” How h...
Cellular therapy: Responding to COVID-19
January 22, 2021 06:00 - 16 minutes - 15.2 MBTimestamps: 00:00 Intro 00:58 How is cellular therapy contributing to the COVID effort? 04:42 Can you give us a little bit of an introduction about what’s so important about the cell (mesenchymal stem cell) or where it comes from? 08:19 What sort of work are you and your lab doing for patient care? 11:14 Once you figure out a successful cellular therapy, is there then opportunity for that to get brought to scale for a given patient population, or does cellular therapy need to ...
COVID-19 vaccinations and laboratory testing
January 08, 2021 06:00 - 12 minutes - 11.4 MB00:00 Intro 00:45 Can you let our listeners know what we know about the vaccines at this point (December 2020)? 02:00 With using the mRNA approach, do these vaccines have similar performance characteristics? 03:00 What does this mean for people after they get vaccinated? Hearing this high numbers of efficacy that is protecting me from the virus, what does this mean for how I should be behaving after I get vaccinated? 04:25 What are your thoughts on if there should be post-vaccin...
The mentoring relationship: It’s a two-way street
December 04, 2020 06:00 - 11 minutes - 11 MBTimestamps: 00:00 Intro 01:00 As Pathologists, we have a lot of competing priorities. Why is mentoring residents and fellows consistently a high priority for you? 03:27 Often what we are trying to do as educators is not transparent to our learners, for a variety of reasons. What do you wish that all residents, fellows, and learners understood about the process of their training? 05:00 How do you address someone who started out on the right food and then started a slip a little a...
Advances in the diagnosis of heparin-induced thrombocytopenia
November 13, 2020 06:00 - 16 minutes - 15 MBTimestamps: 00:00 Intro 01:00 What is HIT and why is it important for clinicians to correctly diagnose HIT? 03:30 What do we know about how laboratory testing may help clinicians get the diagnosis right? 07:25 How could the process of diagnosing HIT be updated or made better? 10:45 What does the future hold for HIT testing? In five years’ time what do you think HIT testing is going to look like in this country? 12:45 How has your relationship with your clinical colleagues ...
Preparing for your pathology residency interview
November 06, 2020 06:00 - 25 minutes - 23.8 MBTimestamps: 00:00 Intro 01:00 Why is it important for medical students to prepare for their residency interviews? 3:00 What do recommend that students do to prepare for those interviews? Is it looking at websites online or going to PubMed? 05:35 Assuming many interviews will be virtual, is it fair game for an applicant to reach out to the program interviewers ahead of time to ask them if they can test out the system if they are unfamiliar with it? 08:45 Do you have any thoughts...
Update: Convalescent Plasma
October 02, 2020 05:00 - 24 minutes - 22.6 MBTime Stamps 00:00 Podcast Intro 00:35 Now that the EAP is closed, how are doctors getting convalescent plasma for their patients? 08:50 What new information have we learned about convalescent plasma in recent months? 13:28 If we are in a period of shortage and there is only low titer available, is it ideal to transfer two units of convalescent plasma in that context? 15:30 What remaining questions about convalescent plasma are you most curious about? 18:52 How can study ...
Laboratory Detection of Opioids
September 11, 2020 05:00 - 13 minutes - 12 MBTime Stamps 00:00 Podcast Intro 00:40 Why is it important for a laboratory to detect or quantify opioids? 02:00 What are the challenges you have had to navigate in the laboratory specific to opioids? 04:47 Is it like a pregnancy test or is it important to quantify as well? 05:19 Can you help us understand how you collaborate with other health care professionals? 07:07 In terms of new or illicit street drugs, are you having to constantly design new tests to detect these things...
Addressing Diversity & Inclusion in Pathology
August 21, 2020 05:00 - 17 minutes - 16 MBTimestamps 00:00 Podcast Intro 00:45 Why is it important for laboratory medicine and pathology to be deliberate about diversity and inclusion? 03:11 How do you recommend we transform the question “will they fit?” or “do I fit?” so that it invites diversity? 05:33 So, it’s not so much of transforming the question but putting it ahead of the interview and thinking about what you are trying to recruit for? 06:22 What information have we recently learned about diversity and inclus...
COVID-19 Testing Update
August 07, 2020 05:00 - 19 minutes - 18.3 MBTime Stamps 00:00 Podcast Intro 00:50 Why does this landscape of COVID testing seem so dynamic? 03:47 So it sounds like we have two sort of rapid tests that are on the market now. Can we dive into that so that we can appreciate a little bit of the compare and contrast between those two rapid assays? 07:17 What are these unique challenges with regards to sensitivity and specificity when it comes to these rapidly evolving tests? 11:08 Highlighting the connection between laborato...
Being Deliberate when Starting Your Career in Pathology
July 24, 2020 05:00 - 28 minutes - 26.2 MBTime Stamps 00:00 Podcast Intro 00:51 This is a nice time of year for the academic calendar with new trainees starting residency, and new faculty starting their jobs, and people still in their first couple of years of being an academic pathologist. Why is it important for these individuals to be deliberate about how they begin their career? 04:18 When somebody is in training, there is a lot that is decided for them and things are predetermined. In residency that opens up quite a ...
Our Opportunity: Helping Patients Understand Laboratory Testing
July 01, 2020 05:00 - 34 minutes - 31.8 MBTime Stamps 00:00 Podcast Intro 01:05 Why is it important to explain the laboratory to patients? How important it is to have open/honest communication with patients? 07:05 With your experience in talking with children and their families is your focus on the child and the parents picks up on your efforts? Or are you addressing the child separately from their parents? 11:10 What tips would you have for pathologists as they approach certain situations (approaching the bedside, en...
Our opportunity: Helping patients understand laboratory testing
July 01, 2020 05:00 - 34 minutes - 31.8 MBTime Stamps 00:00 Podcast Intro 01:05 Why is it important to explain the laboratory to patients? How important it is to have open/honest communication with patients? 07:05 With your experience in talking with children and their families is your focus on the child and the parents picks up on your efforts? Or are you addressing the child separately from their parents? 11:10 What tips would you have for pathologists as they approach certain situations (approaching the bedside, en...
Stop—Collaborate and Listen
June 05, 2020 05:00 - 23 minutes - 21.2 MB00:00 Podcast Intro 00:53 There seems to be a lot of buzz around the need for interprofessional education and interprofessional collaboration. Can you kind of take us through these concepts? How are they the same, or how are they different? 02:37 What’s the why here? Why should health care institutions, us as individuals, why should we prioritize this interprofessional education or collaboration in practice? 05:34 I imagine there are a lot of people listening who have meetings…fo...
The Littlest Things in Life - From Dust to Dust: Microbiology and the Medical Autopsy
May 27, 2020 05:00 - 26 minutes - 24.1 MBTime Stamps 00:00 Podcast Intro 03:19 How did you choose forensic pathology as a career? 04:30 Where did you train and where were you prior to Mayo? 05:08 Can you discuss in general the practice of forensic pathology, and the difference between hospital and medicolegal autopsies? 06:37 How often do forensic pathology and microbiology intersect? 07:57 What are the challenges of performing microbiology studies in your practice? 08:54 What types of interest...
From Dust to Dust: Microbiology and the Medical Autopsy
May 27, 2020 05:00 - 26 minutes - 24.1 MBTime Stamps 00:00 Podcast Intro 03:19 How did you choose forensic pathology as a career? 04:30 Where did you train and where were you prior to Mayo? 05:08 Can you discuss in general the practice of forensic pathology, and the difference between hospital and medicolegal autopsies? 06:37 How often do forensic pathology and microbiology intersect? 07:57 What are the challenges of performing microbiology studies in your practice? 08:54 What types of interesting microbiology cases have y...
Understanding COVID-Associated Coagulopathy
May 06, 2020 05:00 - 18 minutes - 16.8 MBTime Stamps 00:00 Podcast Intro 00:40 What is COVID-associated coagulopathy and why is it important to recognize this? 02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice? 04:30 Is there recommended testing for COVID-associated coagulopathy? 06:30 Can you explain what the soluble fibrin monomer test is? 08:09 How is COVID-associated coagulopathy managed in terms on prophylactic anticoagula...
Convalescent Plasma: Why, How, and Lessons Learned
May 01, 2020 05:00 - 23 minutes - 21.6 MBTime Stamps 00:00 Podcast Intro 00:39 What is they ‘why’ behind starting up a convalescent plasma program? 04:00 If physicians are taking care of a patient and wanting to get this product how do they go about it? 11:23 With the Expanded Access Protocol and Emergency IND, how many products does that get for the given patient? 13:00 Where should we direct people who are interested in being a donor? 14:51 Can you give us an idea on who would be eligible to don...