Conrad Keating, the medical historian, opens his series with an interview with Sir David Weatherall to mark World Malaria Day on April 25th 2010. Sir David was appointed Nuffield Professor of Clinical Medicine in 1974, and in 1989 he founded the Institute of Molecular Medicine (in 2000 it was renamed The Weatherall Institute of Molecular Medicine). Sir David tells the story of the evolution of tropical medicine in Oxford from its inception in the late 1970s to its unrivaled standing in the developing world today.