Blood & Cancer
161 episodes - English - Latest episode: about 3 years ago - ★★★★★ - 31 ratingsThe official podcast feed of MDedge Hematology-Oncology, part of the Medscape Professional Network. On Thursdays, Dr. David Henry interviews key opinion leaders and rising stars in hematology and oncology. The information in this podcast is provided for informational and educational purposes only.
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Episodes
Waist size and prostate cancer death, AI is on par with radiologists for mammograms, and "How I Treat" MDS from ASH Hematologic Malignancies
September 22, 2020 08:00 - 13 minutes - 18.9 MBThis week in Hematology and Oncology news: Large waistline linked to higher risk of prostate cancer death (https://bit.ly/3iRxmya) FOLFOXRI tops doublets as bevacizumab backbone for mCRC (https://bit.ly/32QpTKi) AI algorithm on par with radiologists as mammogram reader (https://bit.ly/35WnAXV) How I Treat: For low-risk MDS, treat 'what bugs patients most' (https://bit.ly/2ZU5TEU) * * * Find more Blood & Cancer at https://www.mdedge.com/podcasts/blood-cancer Email the show at ...
Medical school in the COVID era: Two RCSI students explain how the pandemic has affected them
September 17, 2020 08:00 - 29 minutes - 46.6 MBHow has COVID-19 impacted medical students? Two students from Royal College of Surgeons in Ireland (RCSI), Dublin, describe their experiences in this episode. Evani Patel and Sarah Chen, both second-year medical students at RCSI, tell host David H. Henry, MD, how the COVID-19 pandemic has shaped their educational experience thus far. Now, the pandemic has shifted the students’ education to a mix of virtual and in-person learning at RCSI, but COVID-19 also impacted the pair’s summer stude...
Gene testing for all breast cancer patients with second primary malignancy, atezolizumab for TNBC, pralsetinib for NSCLC, and more
September 15, 2020 08:00 - 11 minutes - 16.4 MBHematology/Oncology News: Study supports multigene panel testing for all breast cancer patients with second primary cancers: https://bit.ly/3m6RyOG Source: https://bit.ly/2ZKXund Atezolizumab TNBC indication ‘in jeopardy’ because of phase 3 results: https://bit.ly/35rqzrl Alert: https://bit.ly/2Reh1HM Trial: https://bit.ly/2ZqqIqX Pralsetinib: Second drug for RET+ NSCLC approved in U.S.: https://bit.ly/3bTdGaz Unexpected results in new COVID-19 ‘cytokine storm’ data: https://bit.ly/3k8f...
How I treat MDS: Dr. Shannon McCurdy talks prognostic scoring, ESAs, HMAs, transplant, and more
September 10, 2020 08:00 - 31 minutes - 49.2 MBTreatment strategies for myelodysplastic syndromes (MDS) vary widely depending upon patients’ prognosis. In this episode, Shannon R. McCurdy, MD, of the University of Pennsylvania, Philadelphia, joined host David H. Henry, MD, to discuss how she treats patients with MDS. To start, Dr. McCurdy evaluates patients using the revised International Prognostic Survival Scale (IPSS-R), which can predict the aggressiveness of MDS. Low IPSS-R scores (<1.5) are associated with low-risk MDS, which ha...
Hem-Onc News: Delaying radiotherapy for high-risk prostate cancer; melanoma experts say 'no' to routine gene profile testing
September 08, 2020 21:48 - 11 minutes - 22.3 MBBlood & Cancer News: Delaying RT for higher-risk prostate cancer found safe: https://bit.ly/2F1cKoQ Source: https://bit.ly/2FaaMCr RTOG 9413: https://bit.ly/2DL2FM4 RTOG 9910: https://bit.ly/2F8itJe HOME-PE trial clarifies which pulmonary embolism patients to treat at home: https://bit.ly/3ibNTN9 Melanoma experts say ‘no’ to routine gene profile testing: https://bit.ly/2Zka10p Source: https://bit.ly/2ZkzerB VTE, sepsis risk increased among COVID-19 patients with cancer: https:/...
Best of the 2020 American Society of Clinical Oncology Annual Meeting
September 03, 2020 08:00 - 27 minutes - 37.6 MBEpisode 94 features the best of ASCO 2020, and we'll see you all with new content for episodes 95 and 96. * * * Best of: How did it go? Nick Andrews and David Henry, MD, discuss how Dr. Henry thought the meeting went from episode 73. Top five abstracts. Dr. Henry and Alan Lyss, MD, discuss their top five abstracts each from episode 74. Preview/review. Howard "Skip" Burris, III, MD, joined Dr. Henry to talk about how ASCO was changing amid the COVID-19 pandemic from episode 68. ...
Hem-Onc News: Aspirin linked to cancer progression in older adults, inhibitor could 'alter landscape' of RET+ tumors, and Black-White gap closing
September 01, 2020 08:00 - 14 minutes - 20.3 MBMDedge Hematology-Oncology news for the first week of September 2020. Aspirin may accelerate cancer progression in older adults: https://bit.ly/2ENHRUc ASPREE trial: https://bit.ly/2QAsMYW Meta-analysis: https://bit.ly/2D6rXnl AsCaP: https://bit.ly/2G06X2I Black/White gap gone: ‘The only cancer where this has happened’: https://bit.ly/3jm8PBm Source: https://bit.ly/3lv4u0m Selpercatinib 'poised to alter the landscape' of RET+ cancers: https://bit.ly/34PYSbs Lung cancer results: ht...
SECURE-SCD: A registry of patients with sickle cell disease and COVID-19
August 27, 2020 08:00 - 19 minutes - 32.7 MBThe SECURE-SCD registry was designed to collect and disseminate information on patients with sickle cell disease (SCD) who develop COVID-19. Two of the registry’s organizers are Amanda Brandow, DO, and Julie Panepinto, MD, both of the Medical College of Wisconsin/Children’s Wisconsin in Milwaukee. In this episode, Dr. Brandow and Dr. Panepinto discuss SECURE-SCD and its findings with host David H. Henry, MD. SECURE-SCD is an online registry that was launched in March 2020. On the regi...
Diabetes + weight loss could mean a higher risk of pancreatic cancer, digital breast tomosynthesis vs digital mammography, and adjuvant chemo is beneficial for some with low-grade glioma
August 25, 2020 08:00 - 9 minutes - 12.4 MBNews for the week of August 24, 2020. Beyond baseline, DBT no better than mammography for dense breasts: https://bit.ly/2FTRnpp Study source: https://bit.ly/2FTLkkI Lead author: https://bit.ly/3graAv0 Subgroups predict adjuvant chemoradiotherapy benefits in low-grade glioma: https://bit.ly/31oHkkr Source: https://bit.ly/3aSVe1j Diabetes plus weight loss equals increased risk of pancreatic cancer: https://bit.ly/2Etmbws Source: https://bit.ly/2EyRBkV For more MDedge podcasts: htttp...
Mason Plumlee: NBA star in the Orlando bubble, medical entrepreneur, and COVID-19 survivor
August 20, 2020 08:00 - 22 minutes - 36.3 MBDr. David Henry welcomes NBA power forward Mason Plumlee. Plumlee, who is now participating in the NBA's controlled COVID-19 environment, affectionately referred to as the "bubble," tested positive for COVID-19 before we knew that loss of taste and smell was a symptom. In a wellness and intellectual change-of-pace episode, Plumlee joins Dr. Henry to talk about his background in medicine and biology, his experiences in the NBA bubble, and his time playing for Duke University. Mason Plum...
Hem Onc News: Chemo-free treatment of mesothelioma, FDA approves liquid biopsy for NSCLC, and swallowable device for esophageal cancer
August 18, 2020 08:00 - 13 minutes - 24.7 MBHematology-Oncology news: Chemo-free management of mesothelioma on horizon: https://bit.ly/2CyL6xY CheckMate 743: https://bit.ly/2CBy6HX INITIATE trial: https://bit.ly/3axxdg8 MAPS2: https://bit.ly/32hWCa0 FDA approves first liquid biopsy/NGS test for lung cancer: https://bit.ly/3258jRn Swallowable 'sponge on a string' to diagnose esophageal cancer: https://bit.ly/3iUbLFb Source: https://bit.ly/2Q0T6en COVID-19 impact: Less chemo, immune checkpoint inhibitors, and steroids: https:...
ISTH 2020: Dr. Hanny Al-Samkari talks VTE in COVID-19, bevacizumab in HHT, and predisposition to thrombosis in NSCLC
August 13, 2020 08:00 - 32 minutes - 50.8 MBHanny Al-Samkari, MD, joins the podcast to discuss thrombosis in COVID-19 and lung cancer patients as well as the use of bevacizumab in patients with hereditary hemorrhagic telangiectasia (HHT). Dr. Al-Samkari, of Massachusetts General Hospital, presented three studies on these topics at the virtual ISTH 2020 Congress. In this episode, Dr. Al-Samkari describes these studies to host David H. Henry, MD. Thrombosis, Bleeding, and the Effect of Anticoagulation on Survival in Critically Ill P...
Immunotherapy doesn't impact COVID mortality, breast cancer screening for the developing world, and 2 FDA approvals
August 11, 2020 08:00 - 12 minutes - 23.6 MBSubscribe to Blood & Cancer: Apple Podcasts, Spotify, Google Podcasts This week in HemOnc news: Study: Immune checkpoint inhibitors don't increase risk of death in cancer patients with COVID-19: https://bit.ly/2PEttQa System provides 'faster, less invasive' method for breast cancer detection: https://bit.ly/3achral Source: https://bit.ly/3gN507j FDA approves belantamab in relapsed/refractory multiple myeloma: https://bit.ly/3ksQtQu FDA approves new drug for diffuse large B-cell lym...
How I treat multiple myeloma: Dr. Gustavo Fonseca talks triple-agent therapy, transplant, and treatment failure
August 06, 2020 08:00 - 31 minutes - 43 MBHow does the community oncologist treat multiple myeloma? Gustavo A. Fonseca, MD, of Florida Cancer Specialists, shares his approach to myeloma treatment with host David H. Henry, MD. At the start of this episode, Dr. Fonseca and Dr. Henry discuss their love of podcasts, mentioning shows that have proven useful to them personally and professionally. The pair then move on to discuss hypothetical myeloma cases and advances in treatment. They cover triple-agent therapy, transplant, and bone...
News from EAU20, ISTH, and AACR's COVID-19 & Cancer meeting: Surgery in renal cell cancer, bevacizumab in HHT, and nosocomial COVID-19
August 04, 2020 10:01 - 10 minutes - 20.5 MBSubscribe to Blood & Cancer: Apple Podcasts, Spotify, Google Podcasts This week in HemOnc News: Higher death rate seen in cancer patients with nosocomial COVID-19 Article: https://bit.ly/2XjRLDq Source: https://bit.ly/3goLGgF Robotic renal surgery bests open partial nephrectomy Article: https://bit.ly/2PhHS4M Source: https://bit.ly/3gqXXBd Large cohort study: Bevacizumab safe, effective for severe HHT bleeds Article: https://bit.ly/2XpuZdj Source: https://bit.ly/2BXHVQg Fo...
Beyond the lungs: How COVID-19 affects the blood, brain, gastrointestinal system, and other organ systems
July 30, 2020 08:00 - 37 minutes - 56.7 MBCOVID-19 can have a negative impact on systems throughout the body, beyond just the lungs, according to a review published in Nature Medicine. Two authors of the review joined host David H. Henry, MD, to discuss their article, “Extrapulmonary manifestations of COVID-19.” Aakriti Gupta, MD, of Columbia University Irving Medical Center, and Kartik Sehgal, MD, of Dana Farber Cancer Institute, discussed: ACE2, the entry receptor for SARS-CoV-2 Neurologic and gastrointestinal manifestation...
RTL 03 - HemOnc News: New 'gold standard' for prostate cancer screening, pandemic could increase cancer deaths, genetic testing for early cancers
July 28, 2020 08:00 - 12 minutes - 23.3 MBSubscribe to Blood & Cancer: Apple Podcasts, Spotify, Google Podcasts This week in HemOnc News: PSMA PET/CT may be new 'gold standard' for prostate cancer staging Source: https://bit.ly/2CRaq2t Study: https://bit.ly/3f18YHL Analysis of early-onset cancer suggests need for genetic testing Source: https://bit.ly/2WZSIR3 AACR Abstract: https://bit.ly/3f18YHL Early screening may halve breast cancer mortality in childhood cancer survivors Source: https://bit.ly/2WZSIR3 Study: https://b...
MDedge Hematology|Oncology Journal Club 01 - All about breast cancer: Lumpectomy margins, partial vs whole breast irradiation, locoregional management after neoadjuvant chemo
July 23, 2020 08:00 - 24 minutes - 39.9 MBWhile relaxing on the Jersey Shore, host and MDedge Hematology/Oncology Editor-in-Chief, David Henry, MD, dove into the July 10, 2020, issue of the Journal of Clinical Oncology. In episode 82, we do the same. J Clin Oncol. 2020 Jul 10. 38(20). 2217-2361. (https://bit.ly/2ZQEJ27) You can follow along with the following articles: Lumpectomy Margins for Invasive Breast Cancer and Ductal Carcinoma in Situ: Current Guideline Recommendations, Their Implications, and Impact (https...
Hematology|Oncology Journal Club 01 - All about breast cancer: Lumpectomy margins, partial vs whole breast irradiation, locoregional management after neoadjuvant chemo
July 23, 2020 08:00 - 24 minutes - 39.9 MBWhile relaxing on the Jersey Shore, host and MDedge Hematology/Oncology Editor-in-Chief, David Henry, MD, dove into the July 10, 2020, issue of the Journal of Clinical Oncology. In episode 82, we do the same. J Clin Oncol. 2020 Jul 10. 38(20). 2217-2361. (https://bit.ly/2ZQEJ27) You can follow along with the following articles: Lumpectomy Margins for Invasive Breast Cancer and Ductal Carcinoma in Situ: Current Guideline Recommendations, Their Implications, and Impact (https...
RTL 02 -- The latest news from MDedge Hematology/Oncology: MRI IDs significant prostate cancer, drug interactions to avoid in GI cancers, ctDNA clearance tracks with NSCLC survival, COVID symptoms persist
July 21, 2020 08:30 - 12 minutes - 23 MBThe latest news from MDedge Hematology/Oncology: In this episode: MRI reliably identifies significant prostate cancer * Original MDedge article (https://bit.ly/3hgKT1h) * PROMIS analysis (https://bit.ly/3fLOiEN) Drug-drug interactions to avoid in patients with GI cancer * Original MDedge article (https://bit.ly/39eHi0G) ctDNA clearance tracks with PFS in NSCLC subtype * Original MDedge article (https://bit.ly/3eJKm6o) * Abstract from AACR 2020 (https://bit.ly/30uQQ3R) * TATTON...
Cancer and diet: Dr. Dawn Lemanne describes how fasting can suppress the immune system and lower IGF-1 and blood sugar levels
July 16, 2020 08:00 - 23 minutes - 38.3 MBCancer patients often ask what they should eat, but it’s just as important to know when they should eat, according to Dawn Lemanne, MD, of Oregon Integrative Oncology, Ashland, and the University of Arizona, Tucson. Dr. Lemanne tells host David H. Henry, MD, how cancer patients may benefit from fasting. The pair discuss immune system suppression, insulinlike growth factor I (IGF-I), and blood glucose monitoring. Fasting and the immune system Fasting before and after chemotherapy can put...
Introducing Run the List: the latest hem onc news - Earlier lung screening doubles eligibility, lifestyle reduces breast cancer risk regardless of genetics, FDA approves MDS/CMML drug, COVID mask exemptions
July 14, 2020 08:30 - 11 minutes - 21.6 MBThe latest news for hematology and oncology professionals. In this episode: USPSTF: Earlier lung cancer screening can double eligibility * Review and comment on the USPSTF site: https://bit.ly/3fppiD7 * National Lung Screening Trial https://bit.ly/2CvNRQt Lifestyle choices may reduce breast cancer risk regardless of genetics * Read the article on MDedge: https://bit.ly/2ZrsWqN * Read the original research: https://bit.ly/3etRLGx (JAMA Netw Open. 2020;3(4):e203760). FDA approves ...
Personal and professional impact of COVID-19 - diary of an oncologist and vacation on the shore
July 09, 2020 08:00 - 19 minutes - 32.7 MBOncologist Don S. Dizon, MD, joins the podcast to discuss how the COVID-19 pandemic has affected him personally and professionally. Dr. Dizon is the director of women’s cancers at Lifespan Cancer Institute and director of medical oncology at Rhode Island Hospital, both in Providence. Dr. Dizon tells host David H. Henry, MD, how COVID-19 affected his patients, colleagues, and research as well as his personal life. Dr. Dizon chronicled some of these developments in a series of columns publis...
Patient anxiety, social support, optimism bias, and 'How long do I have left?': The best-of Dr. Ilana Yurkiewicz
July 02, 2020 08:00 - 29 minutes - 46.7 MBIlana Yurkiewicz, MD, recorded dozens of Clinical Correlation segments for Blood & Cancer for more than a year. She also hosted a three-part series on difficult conversations that trainees have with their patients. In this episode, we revisit the best of Dr. Yurkiewicz. 'How long do I have left?' 02:59 Anxiety 17:02 Optimism Bias 20:21 Social Support 23:51 Family Dynamics 26:07 For more MDedge Podcasts, go to mdedge.com/podcasts Email the show: [email protected] Interac...
EHA25: AML, myeloma, polycythemia vera, and COVID-19 with EHA President John Gribben
June 25, 2020 08:00 - 28 minutes - 39 MBEHA25 highlights: EHA President John Gribben talks AML, myeloma, polycythemia vera, and COVID-19 What were the late-breaking and practice-changing presentations at EHA25 Virtual? John Gribben, MD, DSc, president of the European Hematology Association, highlighted some of them in this podcast. Dr. Gribben and host David H. Henry, MD, discussed presentations on acute myeloid leukemia (AML), multiple myeloma, polycythemia vera (PV), and COVID-19. Videos of these and other presentations wi...
Drugs FDA-approved for hematology / oncology in 2020: ‘Game-changing’ and ‘niche’ indications
June 18, 2020 08:00 - 29 minutes - 46.1 MBThe Food and Drug Administration has approved dozens of drugs for new hematology/oncology indications this year. Host David Henry, MD, was joined by David Mintzer, MD, and other colleagues at Penn Medicine in Philadelphia – Justine Cohen, DO, and Ingrid Kohut, DO – to discuss some of these approvals. Dr. Mintzer reviewed: The “game-changing” approval of niraparib (Zejula) in advanced ovarian, fallopian tube, or primary peritoneal cancer. The “exciting” approval of sacituzumab goviteca...
ASCO 2020: Practice-changing studies in breast, lung, colorectal, and other cancers
June 11, 2020 08:00 - 41 minutes - 63 MBWhat were the practice-changing studies presented at the 2020 ASCO Annual Meeting? Podcast host David H. Henry, MD, and retired oncologist Alan P. Lyss, MD, reviewed 12 studies and assessed their potential impact on treatment. Breast cancer Three-year follow-up of neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2-blockade for HER2-positive breast cancer (TRAIN-2): A randomized phase III trial. (Abstract 501) The addition of anthracyclines did not impr...
Non–small cell lung cancer: How to choose the best therapy and reviewing the first virtual ASCO
June 04, 2020 08:00 - 35 minutes - 54.8 MBJack West, MD, joins the podcast to discuss how he chooses first-line treatment in new patients with non–small cell lung cancer (NSCLC). Dr. West is an associate clinical professor in medical oncology at City of Hope Comprehensive Cancer Center in Duarte, Calif., and a thought leader in thoracic oncology. Dr. West also explores how the COVID-19 pandemic influences treatment approaches, the usefulness of liquid biopsy, and how he weighs the potentially higher risk for COVID-19 complications f...
Non small-cell lung cancer: How to choose the best therapy and reviewing the first virtual ASCO
June 04, 2020 08:00 - 35 minutes - 54.8 MBJack West, MD, joins the podcast to discuss how he chooses first-line treatment in new patients with non–small cell lung cancer (NSCLC). Dr. West is an associate clinical professor in medical oncology at City of Hope Comprehensive Cancer Center in Duarte, Calif., and a thought leader in thoracic oncology. Dr. West also explores how the COVID-19 pandemic influences treatment approaches, the usefulness of liquid biopsy, and how he weighs the potentially higher risk for COVID-19 complications f...
Would you choose oncology again? Plus, breast cancer research: HER2CLIMB, KEYNOTE 522, and DESTINY BREAST01 with Dr. Bill Gradishar
May 28, 2020 08:00 - 27 minutes - 43.5 MBDavid H. Henry, MD, answers the question, "Would you choose oncology again?" This question was asked of oncologists surveyed for the Medscape Oncologist Compensation Report 2020, and 96% of oncologists said they would still choose oncology as their specialty. Later, William J. Gradishar, MD, of Northwestern University in Chicago, joined Dr. Henry to discuss recent developments in breast cancer. Dr. Gradishar reviewed three trials presented at the 2019 San Antonio Breast Cancer Symposium ...
VTE rate, 'COVID toes,' and Virchow's triad: What you need to know about COVID and coagulation
May 21, 2020 08:00 - 32 minutes - 50.9 MBAdam C. Cuker, MD, joins host David H. Henry, MD, to discuss recent findings regarding coagulation in COVID-19 patients. Both Dr. Cuker and Dr. Henry both practice at the Hospital of the University of Pennsylvania in Philadelphia. Dr. Cuker cited data suggesting at least 25%-30% of patients with COVID-19 develop venous thromboembolism (VTE), despite receiving prophylactic anticoagulation. Furthermore, COVID-19 patients have presented with “lots of different thrombotic manifestations,” he s...
VTE rate, "COVID toes," and Virchow's triad: What you need to know about COVID and coagulation
May 21, 2020 08:00 - 32 minutes - 50.9 MBAdam C. Cuker, MD, joins host David H. Henry, MD, to discuss recent findings regarding coagulation in COVID-19 patients. Both Dr. Cuker and Dr. Henry both practice at the Hospital of the University of Pennsylvania in Philadelphia. Dr. Cuker cited data suggesting at least 25%-30% of patients with COVID-19 develop venous thromboembolism (VTE), despite receiving prophylactic anticoagulation. Furthermore, COVID-19 patients have presented with “lots of different thrombotic manifestations,” he s...
An internist’s experience with COVID-19
May 14, 2020 08:00 - 31 minutes - 49 MBIn this episode, Matthew Watto, MD, an internist at Pennsylvania Hospital in Philadelphia, tells host David H. Henry, MD, also of Pennsylvania Hospital, how the COVID-19 pandemic has affected him personally and professionally. Dr. Watto recounts how COVID-19 has impacted patient volume, shifts, teaching, and interactions between patients and staff. Dr. Watto also discusses his internal medicine podcast, The Curbsiders, which, he says, provides listeners with “clinical pearls, practice-chan...
Dr. Matt Watto of The Curbsiders on being an internist in the COVID-19 pandemic
May 14, 2020 08:00 - 31 minutes - 49 MBIn this episode, Matthew Watto, MD, an internist at Pennsylvania Hospital in Philadelphia, tells host David H. Henry, MD, also of Pennsylvania Hospital, how the COVID-19 pandemic has affected him personally and professionally. Dr. Watto recounts how COVID-19 has impacted patient volume, shifts, teaching, and interactions between patients and staff. Dr. Watto also discusses his internal medicine podcast, The Curbsiders, which, he says, provides listeners with “clinical pearls, practice-chan...
Curbsiders Host Dr. Matt Watto on being an internist in the COVID-19 pandemic
May 14, 2020 08:00 - 31 minutes - 49 MBIn this episode, Matthew Watto, MD, an internist at Pennsylvania Hospital in Philadelphia, tells host David H. Henry, MD, also of Pennsylvania Hospital, how the COVID-19 pandemic has affected him personally and professionally. Dr. Watto recounts how COVID-19 has impacted patient volume, shifts, teaching, and interactions between patients and staff. Dr. Watto also discusses his internal medicine podcast, The Curbsiders, which, he says, provides listeners with “clinical pearls, practice-chan...
Treating genitourinary malignancies in the COVID-19 era
May 07, 2020 08:00 - 34 minutes - 52.8 MBHow should oncologists be treating genitourinary malignancies during the COVID-19 pandemic? Aly-Khan A. Lalani, MD, of McMaster University in Hamilton, Ontario, and colleagues recently published recommendations that help answer that question (Can Urol Assoc J. 2020 May;14[5]:e154-8). In this episode, Dr. Lalani reviews some of these recommendations with podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia. The pair discuss when and how to use androgen receptor axis-tar...
The first virtual ASCO meeting; plus Part 2 of tech tools for docs
April 30, 2020 08:00 - 37 minutes - 57 MBThe American Society of Clinical Oncology is gearing up for its first-ever virtual meeting at the end of May 2020. ASCO’s president Howard A. “Skip” Burris, III, MD, joins David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to explain how the virtual meeting will work, from releasing research to earning continuing medical education credits. Dr. Burris also explores how the society is responding to COVID-19. Later in the podcast, Bernard A. Mason, MD, an oncologist with Pennsylvani...
Treating colorectal cancer in the COVID-19 era
April 23, 2020 08:00 - 39 minutes - 59.9 MBOncologists are now weighing the benefits of treating cancer patients against the risk of exposing them to SARS-CoV-2. David Kerr, MD, DSc, of University of Oxford (England) talks with podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, about how to treat colorectal cancer patients in the COVID-19 era. Dr. Kerr cowrote an article on MDedge Hematology/Oncology that outlined recommendations for treating colorectal cancer patients during the pandemic. In this episode, ...
COVID-19 and the community oncologist
April 16, 2020 08:00 - 38 minutes - 53.4 MBHow are community oncologists adapting to the COVID-19 pandemic? Podcast host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, explores this question with Matthew Lonergan, MD, of Willamette Valley Cancer Institute (WVCI) and Research Center in Eugene, Ore. Dr. Lonergan explains how WVCI is attempting to minimize staff exposure to COVID-19, how physicians there are dealing with the transition to telemedicine, and how a lack of resources has affected WVCI. Dr. Lonergan and Dr. ...
COVID-19 and lung cancer: The decision to delay treatment
April 09, 2020 08:00 - 33 minutes - 52 MBIn the “new normal” of treating cancer patients during COVID-19, when do you decide to start treatment or pause it? Narjust Duma, MD, a thoracic oncologist at the University of Wisconsin, Madison, shares how she makes those decisions in partnership with her lung cancer patients and how the discussions are complicated by the fear and uncertainty around the pandemic. Later in the podcast, Dr. Duma and podcast host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, explore how telehe...
Bonus: COVID-19 critical-care lessons from Seattle
April 07, 2020 08:00 - 26 minutes - 23.9 MBAs the nation’s health care system braces for COVID-19 cases, physicians who’ve faced the pandemic first have critical lessons for everyone. In this bonus episode, two Seattle-area critical care leaders explain how their medical centers are preparing for and responding to their region’s early outbreaks. And they share some creative approaches that are uniting Seattle’s critical care departments.
COVID-19: ‘The world has changed’
April 02, 2020 08:00 - 31 minutes - 48.5 MBZainab Shahid, MD, medical director of bone marrow transplant infectious diseases at the Levine Cancer Institute/Atrium Health in Charlotte, N.C., breaks down when cancer patients should seek testing for COVID-19 and how they should be treated. Dr. Shahid also compares notes with Blood & Cancer host David H. Henry, MD, of Pennsylvania Hospital in Philadelphia, on how the COVID-19 pandemic has changed the world of medical education. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford...
Grands rounds in the age of COVID-19; cardiotoxicity in breast cancer
March 26, 2020 08:00 - 32 minutes - 50 MBSusan Dent, MD, codirector of the cardio-oncology program at Duke University in Durham, N.C., reflects on virtual grand rounds, telehealth, the screening of patients before clinic visits, and other new realities of cancer care in the age of COVID-19. Dr. Dent also discusses the importance of assessing breast cancer patients for cardiotoxicity. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about the importance of advance directives. * * * Card...
Tech tools for docs: Apps, sites, and software in the virtual world
March 19, 2020 08:00 - 32 minutes - 50.7 MBDavid Henry, MD, welcomes Bernard A. Mason, MD, to discuss Dr. Mason's favorite digital tools for working as a physician in part 1 of 2. Dr. Mason is an oncologist with the Pennsylvania Hospital and the University of Pennsylvania, both in Philadelphia. Dr. Mason explains the actual benefits for doctors and health care providers for popular apps and services from storage to maps. He and Dr. Henry explore the following: One drive Google Drive Google Photos Google Maps Offline H...
Common bleeding and coagulation issues
March 12, 2020 08:00 - 30 minutes - 47.6 MBThere’s an art to taking a thorough bleeding history. In this episode, Adam Cuker, MD, director of the Hemophilia and Thrombosis Center at the University of Pennsylvania, Philadelphia, shares the most important questions to ask and the challenges in assessing risk in patients about to undergo surgery and those with active bleeding. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about delivering good news to patients. Practice points: Always take...
Is this a good study? The statistics tell the story
March 05, 2020 09:00 - 31 minutes - 49.7 MBEver read through a study and wondered how to apply the hazard ratio, or if you should change your practice because of a secondary endpoint finding? In this episode, Lauren M. Catalano, MD, of the University of Pennsylvania, Philadelphia, explains all the common terms and why they matter in the context of the KEYNOTE-024 trial. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University, talks about how to prepare for an unexpected bad outcome. Practice points: Don’t...
Treatment approaches in AML
February 27, 2020 09:00 - 32 minutes - 51 MBA diagnosis of acute myeloid leukemia (AML) was once an emergency, requiring immediate treatment. Today, the need to start treatment is still urgent, but many patients can benefit by waiting a few days for testing to reveal a fuller picture of the disease. That’s the advice of James M. Foran, MD, of the Mayo Clinic. He joins Blood & Cancer host David H. Henry, MD, of the Pennsylvania Hospital, Philadelphia, to walk through some patient scenarios and the newest treatment options. In Clinica...
Treatment tips in CLL
February 20, 2020 09:00 - 22 minutes - 36.1 MBThe million-dollar question in the treatment of chronic lymphocytic leukemia (CLL) is what to do after a patient relapses following treatment with venetoclax. Anthony Mato, MD, and Lindsey Roeker, MD, both of Memorial Sloan Kettering in New York, join podcast host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to explore the evidence about this question and to review the initial patient work-up and treatment strategies. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanfo...
When to refer for CAR T-cell therapy
February 13, 2020 09:00 - 21 minutes - 34.9 MBChimeric antigen receptor (CAR) T-cell therapy is one of the hottest advances in lymphoma treatment, but who should get it and what does the process look like? Allison Winter, MD, of the Cleveland Clinic helps answer those questions on the podcast. She joins Blood & Cancer host David H. Henry, MD, of the Pennsylvania Hospital, Philadelphia, to break down the side effects and look ahead to possible off-the-shelf products. In Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) ...
Understanding biosimilars
February 06, 2020 09:00 - 19 minutes - 32.7 MBThink of biosimilars as your mother’s minestrone soup: It’s the same recipe and ingredients every time, but not every batch is chemically identical, even if it tastes about the same. That’s how Brian T. Hill, MD, PhD, of the Cleveland Clinic, describes biosimilars. He joins Blood & Cancer host David H. Henry, MD, of Pennsylvania Hospital, Philadelphia, to discuss how biosimilars are made and approved, and how they differ from generic drugs. In Clinical Correlation, Ilana Yurkiewicz, MD, o...